scholarly journals Correlation of minimally invasive imaging techniques to assess intestinal mucosal perfusion with established markers of chronic inflammatory enteropathy in dogs

2020 ◽  
Author(s):  
Mazdak Salavati ◽  
Jorge Pérez‐Accino ◽  
Yi Lin Tan ◽  
Tiziana Liuti ◽  
Sionagh Smith ◽  
...  
Keyword(s):  
Minimally Invasive ◽  
Imaging Techniques ◽  
Mucosal Perfusion

scholarly journals Holistic description of new deep sea megafauna (Cephalopoda: Cirrata) using a minimally invasive approach

BMC Biology ◽  
2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Alexander Ziegler ◽  
Christina Sagorny
Keyword(s):  
Minimally Invasive ◽  
Dna Barcoding ◽  
Deep Sea ◽  
Imaging Techniques ◽  
Structural Complexity ◽  
Micro Computed Tomography ◽  
Invasive Approach ◽  
Non Invasive ◽  
Additional Support ◽  
Holistic Description

Abstract Background In zoology, species descriptions conventionally rely on invasive morphological techniques, frequently leading to damage of the specimens and thus only a partial understanding of their structural complexity. More recently, non-destructive imaging techniques have successfully been used to describe smaller fauna, but this approach has so far not been applied to identify or describe larger animal species. Here, we present a combination of entirely non-invasive as well as minimally invasive methods that permit taxonomic descriptions of large zoological specimens in a more comprehensive manner. Results Using the single available representative of an allegedly novel species of deep-sea cephalopod (Mollusca: Cephalopoda), digital photography, standardized external measurements, high-field magnetic resonance imaging, micro-computed tomography, and DNA barcoding were combined to gather all morphological and molecular characters relevant for a full species description. The results show that this specimen belongs to the cirrate octopod (Octopoda: Cirrata) genus Grimpoteuthis Robson, 1932. Based on the number of suckers, position of web nodules, cirrus length, presence of a radula, and various shell characters, the specimen is designated as the holotype of a new species of dumbo octopus, G. imperator sp. nov. The digital nature of the acquired data permits a seamless online deposition of raw as well as derived morphological and molecular datasets in publicly accessible repositories. Conclusions Using high-resolution, non-invasive imaging systems intended for the analysis of larger biological objects, all external as well as internal morphological character states relevant for the identification of a new megafaunal species were obtained. Potentially harmful effects on this unique deep-sea cephalopod specimen were avoided by scanning the fixed animal without admixture of a contrast agent. Additional support for the taxonomic placement of the new dumbo octopus species was obtained through DNA barcoding, further underlining the importance of combining morphological and molecular datasets for a holistic description of zoological specimens.

Minimally Invasive Palliative Tumor Therapy Guided by Imaging Techniques: The UCLA Experience

1994 ◽  
Vol 12 (2) ◽  
pp. 65-73 ◽  
Author(s):  
DAN J. CASTRO ◽  
ROMAINE E. SAXTON ◽  
JACQUES SOUDANT ◽  
THOMAS CALCATERRA ◽  
ROBERT LUFKIN ◽  
...  
Keyword(s):  
Minimally Invasive ◽  
Imaging Techniques ◽  
Tumor Therapy

scholarly journals Miniature low-cost γ-radiation sensor for localization of radioactively marked lymph nodes

2021 ◽  
pp. 095441192110589
Author(s):  
Merlin Behling ◽  
Felix Wezel ◽  
Peter P Pott
Keyword(s):  
Minimally Invasive ◽  
Lymph Nodes ◽  
Early Stage ◽  
Imaging Techniques ◽  
Low Cost ◽  
In Vitro Tests ◽  
Γ Radiation ◽  
Sensor Head ◽  
Radiation Sensor ◽  
Validation Experiment

Detection of metastasis spread at an early stage of disease in lymph nodes can be achieved by imaging techniques, such as PET and fluoride-marked tumor cells. Intraoperative detection of small metastasis can be problematic especially in minimally invasive surgical settings. A γ-radiation sensor can be inserted in the situs to facilitate intraoperative localization of the lymph nodes. In the minimally invasive setting, the sensor must fit through the trocar and for robot-aided interventions, a small, capsule-like device is favorable. Size reduction could be achieved by using only a few simple electronic parts packed in a single-use sensor-head also leading to a low-cost device. This paper first describes the selection of an appropriate low-cost diode, which is placed in a sensor head (Ø 12 mm) and characterized in a validation experiment. Finally, the sensor and its performance during a detection experiment with nine subjects is evaluated. The subjects had to locate a 137Cs source (138 kBq activity, 612 keV) below a wooden plate seven times. Time to accomplish this task and error rate were recorded and evaluated. The time needed by the subjects to complete each run was 95 ± 68.1 s for the first trial down to 40 ± 23.9 s for the last. All subjects managed to locate the 137Cs source precisely. Further reduction in size and a sterilizable housing are prerequisites for in vitro tests on explanted human lymph nodes and finally in vivo testing.

Prediction of lymph node metastases in vulvar cancer: a review

2006 ◽  
Vol 16 (3) ◽  
pp. 963-971 ◽  
Author(s):  
M. H.M. Oonk ◽  
H. Hollema ◽  
J. A. De Hullu ◽  
A. G.J. Van Der Zee
Keyword(s):  
Lymph Node ◽  
Minimally Invasive ◽  
Negative Predictive Value ◽  
Lymph Node Metastases ◽  
Predictive Value ◽  
Imaging Techniques ◽  
Diagnostic Methods ◽  
Depth Of Invasion ◽  
Sentinel Node Procedure ◽  
Node Metastases

The aim of this study was to review the literature on currently available non- and minimally-invasive diagnostic methods and analysis of primary tumor characteristics for prediction of inguinofemoral lymph node metastases in patients with primary squamous cell carcinoma of the vulva. We used the English language literature in Pubmed and reference lists from selected articles. Search terms included vulvar carcinoma, prognosis, lymph node metastases, ultrasound, computer tomography, magnetic resonance imaging, positron emission tomography, and sentinel lymph node. No study type restrictions were imposed. Currently no noninvasive imaging techniques exist that are able to predict lymph node metastases with a high enough negative predictive value. A depth of invasion ≤1 mm is the only histopathologic parameter that can exclude patients for complete inguinofemoral lymphadenectomy. No other clinicopathologic parameter allows exclusion of lymph node metastases with a high enough negative predictive value. The minimally invasive sentinel node procedure is a promising technique for selecting patients for complete lymphadenectomy, but its safety has not been proven yet.

scholarly journals Cryoablation for Small Renal Masses

2008 ◽  
Vol 2008 ◽  
pp. 1-10 ◽  
Author(s):  
J. L. Dominguez-Escrig ◽  
K. Sahadevan ◽  
P. Johnson
Keyword(s):  
Minimally Invasive ◽  
Partial Nephrectomy ◽  
Imaging Techniques ◽  
Rapid Development ◽  
High Intensity Focused Ultrasound ◽  
Small Renal Masses ◽  
Renal Masses ◽  
Invasive Approach ◽  
Open Partial Nephrectomy ◽  
Ablative Techniques

Advances in imaging techniques (CT and MRI) and widespread use of imaging especially ultrasound scanning have resulted in a dramatic increase in the detection of small renal masses. While open partial nephrectomy is still the reference standard for the management of these small renal masses, its associated morbidity has encouraged clinicians to exploit the advancements in minimally invasive ablative techniques. The last decade has seen the rapid development of laparoscopic partial nephrectomy and novel ablative techniques such as, radiofrequency ablation (RFA), high-intensity focused ultrasound (HIFU), and cryoablation (CA). In particular, CA for small renal masses has gained popularity as it combines nephron-sparing surgery with a minimally invasive approach. Studies with up to 5-year followup have shown an overall and cancer-specific 5-year survival of 82% and 100%, respectively. This manuscript will focus on the principles and clinical applications of cryoablation of small renal masses, with detailed review of relevant literature.

Minimally Invasive Radioguided Parathyroidectomy

2008 ◽  
Vol 139 (2_suppl) ◽  
pp. P40-P41
Author(s):  
David Goldenberg ◽  
Eelam Adil ◽  
Fred G Fedok ◽  
Tabrez Adil
Keyword(s):  
Minimally Invasive ◽  
Imaging Techniques ◽  
Case Series ◽  
Retrospective Chart Review ◽  
Accurate Localization ◽  
Parathyroid Adenomas ◽  
Significant Difference ◽  
Radioguided Parathyroidectomy ◽  
Sestamibi Scanning ◽  
The Mean

Objective Parathyroid surgery is often challenging due to considerable variability in anatomy. Minimally invasive radioguided parathyroidectomy (MIRP) is a surgical option that has been made possible by the advent of new imaging techniques, specifically Sestamibi scanning. In this study, we review our experience, methods, and outcomes with MIRP in one of the largest case series reported in the literature. Methods A retrospective chart review was performed on 365 patients who underwent MIRP between 1997 and 2007. Data including symptoms, pre- and postoperative calcium levels, and PTH levels were collected. Analyses were performed using Excel AnaylsisPak. Results Intraoperatively, an average of 20mCi Tc-99m was injected for Sestamibi scanning. The mean pre-op calcium was 10.9, whereas the mean post-op level was 9.8. There was a significant difference between pre-op and post-op calcium levels (both ionized and total) (p<.01). Mean pre- and post-op PTH levels were 277 and 46 respectively. Rapid PTH levels were therefore significantly lower post-operatively (p<.01). Conclusions MIRP is an effective method for removal of parathyroid adenomas. The benefits of MIRP include more accurate localization, shorter operative and recovery time, a shorter hospital stay, and better cosmetic results.

scholarly journals Multi-View 3D Skin Feature Recognition and Localization for Patient Tracking in Spinal Surgery Applications

2020 ◽  
Author(s):  
Francesca Manni ◽  
Marco Mamprin ◽  
Ronald Holthuizen ◽  
Caifeng Shan ◽  
Gustav Burstöm ◽  
...  
Keyword(s):  
Minimally Invasive ◽  
Feature Detection ◽  
Feature Recognition ◽  
Imaging Techniques ◽  
Ground Truth ◽  
Computer Assisted ◽  
Clinical Workflow ◽  
Localization Accuracy ◽  
Patient Tracking ◽  
Assisted Navigation

Abstract Background: Minimally invasive spine surgery is dependent on accurate navigation. Computer-assisted navigation is increasingly used in minimally invasive surgery (MIS), but current solutions require the use of reference markers in the surgical field for both patient and instruments tracking. Purpose: To improve reliability and facilitate clinical workflow, this study proposes a new marker-free tracking framework based on skin feature recognition. Methods: Maximally Stable Extremal Regions (MSER) and Speeded Up Robust Feature (SURF) algorithms are applied for skin feature detection. The proposed tracking framework is based on a multi-camera setup for obtaining multi-view acquisitions of the surgical area. Features can then be accurately detected using MSER and SURF and afterwards localized by triangulation. The triangulation error is used for assessing the localization quality in 3D. Results: The framework was tested on a cadaver dataset and in eight clinical cases. The detected features for the entire patient datasets were found to have an overall triangulation error of 0.207 mm for MSER and 0.204 mm for SURF. The localization accuracy was compared to a system with conventional markers, serving as a ground truth. An average accuracy of 0.627 and 0.622 mm was achieved for MSER and SURF, respectively. Conclusions: This study demonstrates that skin feature localization for patient tracking in a surgical setting is feasible. The technology shows promising results in terms of detected features and localization accuracy. In the future, the framework may be further improved by exploiting extended feature processing using modern optical imaging techniques for clinical applications where patient tracking is crucial.

scholarly journals Imaging techniques as a method of sectional examination in forensic veterinary medicine

2018 ◽  
Vol 74 (1) ◽  
pp. 6005-2018
Author(s):  
MAŁGORZATA GRELA ◽  
PIOTR LISTOS ◽  
MAGDALENA GRYZIŃSKA ◽  
WOJCIECH CHAGOWSKI ◽  
GRZEGORZ BUSZEWICZ ◽  
...  
Keyword(s):  
Veterinary Medicine ◽  
Minimally Invasive ◽  
Imaging Techniques ◽  
Comprehensive Analysis ◽  
The Body ◽  
Minimally Invasive Techniques ◽  
Pathological Changes ◽  
Body Scanning ◽  
Non Invasive ◽  
Invasive Techniques

An autopsy or necropsy can be performed only once; therefore, its proper execution is of fundamental importance in explaining the cause of death. The protocol with photographic documentation is an integral part of the autopsy, but sometimes it does not fully reflect the state of the body and the pathological changes observed at each stage of the procedure. These shortcomings are addressed by modern imaging techniques, which are increasingly used during the autopsy of human bodies, but quite rarely during necropsy of animals. Non-invasive techniques (CT, MRI, or photogrammetry with laser body scanning), or in some cases also minimally invasive techniques (biopsy), enable comprehensive analysis of the carcass, but Virtopsy is only a supplement to the classical autopsy, especially in veterinary forensic medicine..

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