Leptospira noguchii associated to reproductive disease in ruminants

2021 ◽  
Author(s):  
Luiza Aymée ◽  
Maria Isabel Nogueira Di Azevedo ◽  
Juliana dos Santos Loria Melo ◽  
Mario Felipe Alvarez Balaro ◽  
Gabriel Mendes de Souza Martins ◽  
...  
Keyword(s):  
Reproductive Disease

scholarly journals Sneathia: an emerging pathogen in female reproductive disease and adverse perinatal outcomes

2021 ◽  
pp. 1-26
Author(s):  
Kevin R. Theis ◽  
Violetta Florova ◽  
Roberto Romero ◽  
Andrei B. Borisov ◽  
Andrew D. Winters ◽  
...  
Keyword(s):  
Perinatal Outcomes ◽  
Emerging Pathogen ◽  
Reproductive Disease ◽  
Adverse Perinatal Outcomes

scholarly journals Nanotechnology and Reproductive Management of Farm Animals: Challenges and Advances

Animals ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1932
Author(s):  
Nesrein M. Hashem ◽  
Antonio Gonzalez-Bulnes
Keyword(s):  
Management Strategies ◽  
Farming Systems ◽  
Biological Molecules ◽  
Farm Animals ◽  
Physiological Status ◽  
Livestock Farming ◽  
Reproductive Management ◽  
Livestock Farming Systems ◽  
Reproductive Disease ◽  
Nutritional Strategies

Reproductive efficiency of farm animals has central consequences on productivity and profitability of livestock farming systems. Optimal reproductive management is based on applying different strategies, including biological, hormonal, nutritional strategies, as well as reproductive disease control. These strategies should not only guarantee sufficient reproductive outcomes but should also comply with practical and ethical aspects. For example, the efficiency of the biological- and hormonal-based reproductive strategies is mainly related to several biological factors and physiological status of animals, and of nutritional strategies, additional factors, such as digestion and absorption, can contribute. In addition, the management of reproductive-related diseases is challenged by the concerns regarding the intensive use of antibiotics and the development of antimicrobial resistant strains. The emergence of nanotechnology applications in livestock farming systems may present innovative and new solutions for overcoming reproductive management challenges. Many drugs (hormones and antibiotics), biological molecules, and nutrients can acquire novel physicochemical properties using nanotechnology; the main ones are improved bioavailability, higher cellular uptake, controlled sustained release, and lower toxicity compared with ordinary forms. In this review, we illustrate advances in the most common reproductive management strategies by applying nanotechnology, considering the current challenges of each strategy.

scholarly journals Genetic Causes of Human Reproductive Disease

2002 ◽  
Vol 87 (6) ◽  
pp. 2447-2454 ◽  
Author(s):  
John C. Achermann ◽  
Gokhan Ozisik ◽  
Joshua J. Meeks ◽  
J. Larry Jameson
Keyword(s):  
Genetic Causes ◽  
Human Reproductive ◽  
Reproductive Disease

scholarly journals Emerging roles for nucleoporins in reproductive cellular physiology

2019 ◽  
Vol 97 (4) ◽  
pp. 257-264
Author(s):  
Claudia C. Preston ◽  
Emily C. Storm ◽  
Riley J. Leonard ◽  
Randolph S. Faustino
Keyword(s):  
Next Generation Sequencing ◽  
Nucleocytoplasmic Transport ◽  
Human Reproduction ◽  
Nuclear Pore ◽  
Next Generation ◽  
Nuclear Trafficking ◽  
Next Generation Sequencing Technology ◽  
Powerful Approach ◽  
Reproductive Disease ◽  
Generation Sequencing

Nucleoporins are a specialized subset of nuclear proteins that comprise the nuclear pore complex and regulate nucleocytoplasmic transport. Recent demonstrations of roles for individual nucleoporins in multiple paradigms of differentiation via mechanisms independent of nuclear trafficking represent conceptual advances in understanding the contributions of nucleoporins to cellular development. Among these, a functional role for nucleoporins in reproductive fitness and gametogenesis has been identified, supported by robust models and clinical studies that leverage the power of next generation sequencing technology to identify reproductive-disease-associated mutations in specific nucleoporins. Proper nucleoporin function manifests in different ways during oogenesis and spermatogenesis. However, nonhuman models of gametogenesis may not recapitulate human mechanisms, which may confound translational interpretation and relevance. To circumvent these limitations, identification of reproductive pathologies in patients, combined with next generation sequencing approaches and advanced in silico tools, offers a powerful approach to investigate the potential function of nucleoporins in human reproduction. Ultimately, elucidating the role of nucleoporins in reproductive biology will provide opportunities for predictive, diagnostic, and therapeutic strategies to address reproductive disorders.

scholarly journals Faktor Usia Ibu dan Paritas Meningkatkan Kejadian Mioma Uteri

2018 ◽  
Vol 11 (1) ◽  
pp. 21
Author(s):  
Army Novitasari ◽  
Gangsar Indah Lestari ◽  
Martini Fairus
Keyword(s):  
Maternal Age ◽  
Uterine Myoma ◽  
Bivariate Analysis ◽  
Chi Square ◽  
Cross Sectional ◽  
Chi Square Test ◽  
Reproductive Disease ◽  
Independent Variable ◽  
Cross Sectional Design ◽  
The Relationship

<p><strong><em>Background:</em></strong><strong><em> </em></strong><em>The most common reproductive disease among Indonesian women is uterine myoma. The number of occurrences of this disease in Indonesia ranks second after cervical cancer. </em><strong><em>Purpose:</em></strong><em> </em><em>This study aims to determine the relationship between maternal age and parity with the incidence of uterine myoma at Mardi Waluyo Metro Hospital in 2016.</em><em> </em><strong><em>Methods:</em></strong><em> </em><em>This study uses a cross sectional design. The study sample was 141 respondents. The independent variable of the study was maternal age and parity, while the dependent variable was uterine myoma. Data analysis using univariate and bivariate analysis. Bivariate analysis using chi square test.</em><em> </em><strong><em>Results:</em></strong><em> </em><em>The results showed that there was a relationship between maternal age (p = 0,000) and parity (p = 0,000) with the incidence of uterine myoma at Mardi Waluyo Metro Hospital.</em><em> </em><strong><em>Conclusion:</em></strong><em> </em><em>The conclusions of this study are maternal age and parity are factors that increase the incidence of uterine myoma. Prevention efforts and reducing the incidence of uterine myoma need to be improved by early detection of women with age and risky parity.</em><em></em></p>

scholarly journals Intratracheal Inoculation with Brucella melitensis in the Pregnant Guinea Pig Is an Improved Model for Reproductive Pathogenesis and Vaccine Studies

2020 ◽  
Vol 88 (10) ◽  
Author(s):  
Martha E. Hensel ◽  
Sankar P. Chaki ◽  
Lauren Stranahan ◽  
Anthony E. Gregory ◽  
Erin J. van Schaik ◽  
...  
Keyword(s):  
Guinea Pig ◽  
Guinea Pigs ◽  
Pregnancy Loss ◽  
Brucella Melitensis ◽  
Reproductive Failure ◽  
Content Type ◽  
Spontaneous Pregnancy ◽  
Important Complication ◽  
Reproductive Disease ◽  
Improved Model

ABSTRACT Reproductive failure is the hallmark of brucellosis in animals. An uncommon but important complication in pregnant women who become acutely infected with Brucella melitensis is spontaneous pregnancy loss or vertical transmission to the fetus. Unfortunately, the mechanism behind reproductive failure is still obscure, partially due to the lack of a proper study model. Recently, it was demonstrated that intratracheal (IT) inoculation of nonpregnant guinea pigs would replicate features of clinical disease in humans. To determine if IT inoculation would induce reproductive disease, guinea pigs were infected at mid-gestation and monitored daily for fever and abortions. Fever developed between day 14 to 18 postinoculation, and by 3 weeks postinoculation, 75% of pregnant guinea pigs experienced stillbirths or spontaneous abortions mimicking natural disease. Next, to investigate the guinea pig as a model for evaluating vaccine efficacy during pregnancy, nonpregnant guinea pigs were vaccinated with S19, 16MΔvjbR + Quil-A, or 100 μl PBS + Quil-A (as control). Guinea pigs were bred and vaccinated guinea pigs were challenged at mid-gestation with B. melitensis IT inoculation and monitored for fever and abortions. Vaccination with both vaccines prevented fever and protected against abortion. Together, this study indicates that pregnant guinea pigs are an appropriate animal model to study reproductive disease and offer an improved model to evaluate the ability of vaccine candidates to protect against a serious manifestation of disease.

Veterinary care of green iguanas (Iguana iguana) part 2

2019 ◽  
Vol 24 (8) ◽  
pp. 432-441
Author(s):  
Marie Kubiak
Keyword(s):  
Infectious Disease ◽  
Renal Disease ◽  
Treatment Options ◽  
Sample Collection ◽  
Health Concerns ◽  
Clinical Procedures ◽  
Associated Conditions ◽  
Reproductive Disease ◽  
The Common ◽  
Green Iguanas

Part one of this series discussed husbandry. This article (part 2) covers clinical procedures including sample collection, fluid therapy and anaesthesia and common presenting health concerns. These can be subdivided into non-infectious or husbandry associated conditions, and infectious disease. Nutritional secondary hyperparathyroidism, reproductive disease in females and renal disease are common reasons for seeking veterinary care. Presentation, diagnosis and treatment options are discussed for the common conditions.

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