Iron deficiency among blood donors: experience from the Danish Blood Donor Study and from the Copenhagen ferritin monitoring scheme

AbstractObjectiveThe objective of this study is to determine the prevalence of iron deficiency (ID) and iron deficiency anaemia (IDA) as well as general anaemia in male blood donors and their association with ageing process.Methodology and ResultsA total of two hundred and one (201) serum samples were analysed for ferritin in male Gambian blood donors. The ferritin measurement was achieved with COBAS® INTEGRA 400 plus. At the same time, haemoglobin values were retrospectively obtained from the archived haematological full blood count result in the GARIS database. IDA was defined as (Haemoglobin <13.0g/dL+ Ferritin<15ng/ml) whilst ID was defined as (Haemoglobin ≥13.0g/dL+ Ferritin<15ng/ml) and general anaemia was defined as haemoglobin <13.0g/dL in males. The prevalence of anaemia (20%, n=41), ID (22%, n=44) and IDA (10%, n=21), were recorded in male donors. The results show no relationship between ferritin and haemoglobin among the blood donors (collection coefficient (r) = 0.04). Besides, no linear association of having anaemia and ID with ageing was reported among the blood donor population.Conclusion and potential application of findingsID and IDA as well as general anaemia are highly prevalent among blood donors in the Gambia. Besides, no predisposition to ID and anaemia was observed in term of age, thus all blood donors from 18-60 should be considered for blood donation without any age preference.

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Physiological Parameters to Identify Suitable Blood Donor Cows for Preparation of Platelet Rich Plasma

Animals ◽

10.3390/ani11082296 ◽

2021 ◽

Vol 11 (8) ◽

pp. 2296

Author(s):

Anna Lange-Consiglio ◽

Rosangela Garlappi ◽

Chiara Spelta ◽

Antonella Idda ◽

Stefano Comazzi ◽

...

Keyword(s):

Blood Donor ◽

Blood Donors ◽

Platelet Rich Plasma ◽

Bovine Mastitis ◽

Field Conditions ◽

Blood Collection ◽

Experimental Conditions ◽

Acute Mastitis ◽

Donor Cows ◽

The Ideal

Platelet rich plasma (PRP) has been shown to be beneficial in the treatment of bovine mastitis, with an action comparable to that of antibiotics. Autologous treatment is feasible in experimental conditions but is difficult to apply in field conditions, particularly in acute mastitis. The ideal scenario would be to have heterologous PRP stored on every farm so that it is readily available when needed. In this paper, we analysed data collected during bovine mastitis treatment with heterologous PRP produced by casual donor cows on several farms. We tried to identify parameters which might be useful to identify the most suitable cows to be used as blood donors, to obtain the highest yield of PRP. Variables considered for each animal were the age, the parity, the date of the last parturition, the season of blood collection, the site of blood collection (jugular or mammary vein) and the reproductive status e.g., pregnant or not pregnant. There were statistically significant differences for all the variables considered from the 135 blood cows, except for the blood collection season. The highest yield of PRP was associated with nonpregnancy blood collection within three months of parturition, parity 3 or 4, and blood collection from the mammary vein.

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A randomized, blinded, placebo-controlled trial of education and iron supplementation for mitigation of iron deficiency in regular blood donors

Transfusion ◽

10.1111/trf.13469 ◽

2016 ◽

Vol 56 (6pt2) ◽

pp. 1588-1597 ◽

Cited By ~ 33

Author(s):

Alan E. Mast ◽

Walter Bialkowski ◽

Barbara J. Bryant ◽

David J. Wright ◽

Rebecca Birch ◽

...

Keyword(s):

Iron Deficiency ◽

Iron Supplementation ◽

Blood Donors ◽

Controlled Trial

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Seroprevalence of transfusion transmissible infections (TTI) in voluntary blood donor(VD) and replacement blood donors(RD): Two years retrospective study in a tribal hamlet in rural Telangana

Medpusle International Journal of Pathology ◽

10.26611/1051935 ◽

2021 ◽

Vol 19 (3) ◽

pp. 77-79

Author(s):

Sylvester Noel ◽

Keyword(s):

Retrospective Study ◽

Blood Donor ◽

Blood Donors ◽

Voluntary Blood Donor

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Reduction of exposure to blood donors in preterm infants submitted to red blood cell transfusions using pediatric satellite packs

Revista Paulista de Pediatria ◽

10.1590/s0103-05822013000300003 ◽

2013 ◽

Vol 31 (3) ◽

pp. 285-292 ◽

Cited By ~ 1

Author(s):

Cristina Lika Uezima ◽

Ariane Moreira Barreto ◽

Ruth Guinsburg ◽

Akemi Kuroda Chiba ◽

José Orlando Bordin ◽

...

Keyword(s):

Birth Weight ◽

Preterm Infants ◽

Blood Donor ◽

Blood Donors ◽

Newborn Infants ◽

Median Number ◽

Erythrocyte Transfusion ◽

Factors Associated ◽

Group 2 ◽

Group 1

OBJECTIVE: In preterm newborn infants transfused with erythrocytes stored up to 28 days, to compare the reduction of blood donor exposure in two groups of infants classified according to birth weight. METHODS: A prospective study was conducted with preterm infants with birth weight <1000g (Group 1) and 1000-1499g (Group 2), born between April, 2008 and December, 2009. Neonates submitted to exchange transfusions, emergency erythrocyte transfusion, or those who died in the first 24 hours of life were excluded. Transfusions were indicated according to the local guideline using pediatric transfusion satellite bags. Demographic and clinical data, besides number of transfusions and donors were assessed. . Logistic regression analysis was performed to determine factors associated with multiple transfusions. RESULTS: 30 and 48 neonates were included in Groups 1 and 2, respectively. The percentage of newborns with more than one erythrocyte transfusion (90 versus 11%), the median number of transfusions (3 versus 1) and the median of blood donors (2 versus 1) were higher in Group 1 (p<0.001), compared to Group 2. Among those with multiple transfusions, 14 (82%) and one (50%) presented 50% reduction in the number of blood donors, respectively in Groups 1 and 2. Factors associated with multiple transfusions were: birth weight <1000g (OR 11.91; 95%CI 2.14-66.27) and presence of arterial umbilical catheter (OR 8.59; 95%CI 1.94-38.13), adjusted for confounders. CONCLUSIONS: The efficacy of pediatrics satellites bags on blood donor reduction was higher in preterm infants with birth weight <1000g.

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Effects of Iron Dietary Supplements to Prevent Iron Deficiency in Repeat Blood Donors

The Korean Journal of Blood Transfusion ◽

10.17945/kjbt.2021.32.2.102 ◽

2021 ◽

Vol 32 (2) ◽

pp. 102-111

Author(s):

Ja Young Lee ◽

Jae Sook Lee ◽

Deuk Yeong Ko ◽

Ji Yeong Seon ◽

Jin Hyuk Yang ◽

...

Keyword(s):

Iron Deficiency ◽

Dietary Supplements ◽

Blood Donors

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TO ANALYSE THE DEFERRAL INCIDENCE AND ITS PATTERN AMONG THE BLOOD DONORS IN A TERTIARY CARE CENTRE IN NORTH INDIA.

International Journal of Medical and Biomedical Studies ◽

10.32553/ijmbs.v3i8.445 ◽

2019 ◽

Vol 3 (8) ◽

Author(s):

Dr. Surbhi Jain

Keyword(s):

Blood Donor ◽

Blood Donors ◽

Blood Donation ◽

Selection Process ◽

Tertiary Care ◽

Clinical History ◽

North India ◽

Tertiary Care Centre ◽

One Year ◽

Donor Deferral

Background: Blood donor programme is vital to any transfusion service. This process of blood donation involves voluntary and non remunerated blood donors. The objective of donor screening is to minimize the chances of transmitting infectious agents to recipients. Material and Method: The study was conducted during one year duration from 2017-2018. A total of 700 donors are deferred against 9556 blood donors recruited on the basis of clinical history and brief medical examination in blood bank and voluntary blood donation camps. Donors were deferred temporarily or permanently. Result: Out of 700 deferred donors; 546 were voluntary and 154 were replacement blood donors. Male (601) outnumbered female (99). There were 682 temporary and 18 permanent deferral. Most common age group for deferral was 17-30 yrs (490). Common causes included anemia(142), on medication(108), underweight(83) and high blood pressure(72). Conclusion: Donor selection process is a most important preliminary step in blood banking and should follow stringent medical and regulatory rules. Studying and analysing the profile of blood donors will help to identify sections of the population which could be targeted to increase the pool of voluntary blood donors. Every attempt should be made to decrease the donor deferral keeping in view the safety of both donor and recipients. Keywords: Blood donor, Deferral, Voluntary, Temporary, Permanent.

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Detection of Toxoplasma Gondii Antibodies and DNA Among Renal Transplant Recipient and blood donor in Khartoum State, Sudan

International Journal of Scientific Research in Science and Technology ◽

10.32628/ijsrst218525 ◽

2021 ◽

pp. 135-141

Author(s):

Elghazali Mohammed ◽

Mustafa Yassin ◽

Khalid Anan ◽

Dina N Abdelrahman ◽

Abdelrahim M. ElHussein ◽

...

Keyword(s):

Toxoplasma Gondii ◽

Renal Transplant ◽

Transplant Recipient ◽

Renal Transplant Recipient ◽

Blood Donor ◽

Blood Donors ◽

Solid Organ ◽

Renal Transplant Recipients ◽

Transplant Recipients ◽

Toxoplasma Gondii Infection

Background and Aim: Toxoplasma gondii infection arises in transplant recipient groups, but at varying frequencies. Reactivation of latent T. gondii infection in transplant patients is uncommon, but does occur. The incidence of reactivation is greater in patient groups receiving more aggressive immunosuppressive therapy. Early diagnosis and treatment should be considered in T. gondii-antibody-positive patients subjected to solid organ transplantation. The aim of this study was to estimate the seroprevalence of Toxoplasma gondii infection in renal transplant recipients in Khartoum, Sudan, using serological and molecular methods. Methods: This was a descriptive cross sectional, hospital based study, blood sample were collected from 108 participants; out of them 58 renal transplant recipient individuals and 50 healthy Blood donor attending Sudanese Kidney Association Hospital and Sudan Heart Center Blood Bank. Demographic data were collected by structured questionnaire. All samples were tested for anti-Toxoplasma IgG and IgM antibodies using ELISA, and PCR for detection of Toxoplasma DNA was performed. Results: The seropositivity of IgG anti-T. gondii antibodies was higher in renal transplant recipients than in blood donors (36.2% vs 32.0%). Anti-toxoplasma IgM was positive in one renal transplant recipient individual (1.70%), and no samples exhibit reactive IgM antibody for blood donors. None of the samples exhibited positivity to T.gondii DNA. Conclusion: the study showed a relatively high seroprevalence of T.gondii antibodies in renal transplant recipients and blood donor volunteers, on the other hand, the prevalence was much higher in the study conducted in pregnant woman in Sudan. Our study highlighted that asymptomatic blood donors, may constitute a significant risk of transmitting toxoplasmosis to susceptible recipients.

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