Characterization of Transition to Turbulence for Blood in a Straight Pipe Under Steady Flow Conditions

2016 ◽  
Vol 138 (7) ◽  
Author(s):  
Dipankar Biswas ◽  
David M. Casey ◽  
Douglas C. Crowder ◽  
David A. Steinman ◽  
Yang H. Yun ◽  
...  

Blood is a complex fluid that, among other things, has been established to behave as a shear thinning, non-Newtonian fluid when exposed to low shear rates (SR). Many hemodynamic investigations use a Newtonian fluid to represent blood when the flow field of study has relatively high SR (>200 s−1). Shear thinning fluids have been shown to exhibit differences in transition to turbulence (TT) compared to that of Newtonian fluids. Incorrect prediction of the transition point in a simulation could result in erroneous hemodynamic force predictions. The goal of the present study was to compare velocity profiles near TT of whole blood and Newtonian blood analogs in a straight rigid pipe with a diameter 6.35 mm under steady flow conditions. Rheology was measured for six samples of whole porcine blood and three samples of a Newtonian fluid, and the results show blood acts as a shear thinning non-Newtonian fluid. Measurements also revealed that blood viscosity at SR = 200 s−1 is significantly larger than at SR = 1000 s−1 (13.8%, p < 0.001). Doppler ultrasound (DUS) was used to measure velocity profiles for blood and Newtonian samples at different flow rates to produce Reynolds numbers (Re) ranging from 1000 to 3300 (based on viscosity at SR = 1000 s−1). Two mathematically defined methods, based on the velocity profile shape change and turbulent kinetic energy (TKE), were used to detect TT. Results show similar parabolic velocity profiles for both blood and the Newtonian fluid for Re < 2200. However, differences were observed between blood and Newtonian fluid velocity profiles for larger Re. The Newtonian fluid had blunt-like velocity profiles starting at Re = 2403 ± 8 which indicated transition. In contrast, blood did not show this velocity profile change until Re = 2871 ± 104. The Newtonian fluid had large velocity fluctuations (root mean square (RMS) > 20%) with a maximum TKE near the pipe center at Re = 2316 ± 34 which indicated transition. In contrast, blood results showed the maximum TKE at Re = 2806 ± 109. Overall, the critical Re was delayed by ∼20% (p < 0.001) for blood compared to the Newtonian fluid. Thus, a Newtonian assumption for blood at flow conditions near transition could lead to large errors in velocity prediction for steady flow in a straight pipe. However, these results are specific to this pipe diameter and not generalizable since SR is highly dependent on pipe diameter. Further research is necessary to understand this relation in different pipe sizes, more complex geometries, and under pulsatile flow conditions.

2000 ◽  
Author(s):  
Paul F. Fischer ◽  
Seung Lee ◽  
Francis Loth ◽  
Hisham S. Bassiouny ◽  
Nurullah Arslan

Abstract This was a study to compare computational and experimental results of flow field inside the venous anastomosis of an arteriovenous (AV) graft. Laser Doppler anemometry (LDA) measurements were conducted inside an upscaled end-to-side graft model under steady flow conditions at Reynolds number 1820 which is representative of the in vivo flow conditions inside a human AV graft. The distribution of the velocity and turbulence intensity was measured at several locations in the plane of the bifurcation. This flow field was simulated using computation fluid dynamics (CFD) and shown to be in good agreement. Under steady flow conditions, the flow field demonstrated an unsteady character (transition to turbulence).


2013 ◽  
Vol 724 ◽  
pp. 95-122 ◽  
Author(s):  
C. Ancey ◽  
N. Andreini ◽  
G. Epely-Chauvin

AbstractThis paper addresses the dam-break problem for particle suspensions, that is, the flow of a finite volume of suspension released suddenly down an inclined flume. We were concerned with concentrated suspensions made up of neutrally buoyant non-colloidal particles within a Newtonian fluid. Experiments were conducted over wide ranges of slope, concentration and mass. The major contributions of our experimental study are the simultaneous measurement of local flow properties far from the sidewalls (velocity profile and, with lower accuracy, particle concentration) and macroscopic features (front position, flow depth profile). To that end, the refractive index of the fluid was adapted to closely match that of the particles, enabling data acquisition up to particle volume fractions of 60 %. Particle migration resulted in the blunting of the velocity profile, in contrast to the parabolic profile observed in homogeneous Newtonian fluids. The experimental results were compared with predictions from lubrication theory and particle migration theory. For solids fractions as large as 45 %, the flow behaviour did not differ much from that of a homogeneous Newtonian fluid. More specifically, we observed that the velocity profiles were closely approximated by a parabolic form and there was little evidence of particle migration throughout the depth. For particle concentrations in the 52–56 % range, the flow depth and front position were fairly well predicted by lubrication theory, but taking a closer look at the velocity profiles revealed that particle migration had noticeable effects on the shape of the velocity profile (blunting), but had little impact on its strength, which explained why lubrication theory performed well. Particle migration theories (such as the shear-induced diffusion model) successfully captured the slow evolution of the velocity profiles. For particle concentrations in excess of 56 %, the macroscopic flow features were grossly predicted by lubrication theory (to within 20 % for the flow depth, 50 % for the front position). The flows seemed to reach a steady state, i.e. the shape of the velocity profile showed little time dependence.


2019 ◽  
Vol 22 (5) ◽  
pp. 1378-1394 ◽  
Author(s):  
Isabela Birs ◽  
Cristina Muresan ◽  
Dana Copot ◽  
Ioan Nascu ◽  
Clara Ionescu

Abstract This paper proposes a framework for modelling velocity profiles and suspended objects in non-Newtonian fluid environment. A setup is proposed to allow mimicking blood properties and arterial to venous dynamic flow changes. Navier-Stokes relations are employed followed by fractional constitutive equations for velocity profiles and flow. The theoretical analysis is performed under assumptions of steady and pulsatile flow conditions, with incompressible properties. The fractional derivative model for velocity and friction drag effect upon a suspended object are determined. Experimental data from such an object is then recorded in real-time and identification of a fractional order model performed. The model is determined from step input changes during pulsatile flow for velocity in the direction of the flow. Further on, this model can be employed for controller design purposes for velocity and position in pulsatile non-Newtonian fluid flow.


Author(s):  
Rayanne Pinto Costa ◽  
Blaise Simplice Talla Nwotchouang ◽  
Junyao Yao ◽  
Dipankar Biswas ◽  
David Casey ◽  
...  

Abstract Blood, a multiphase fluid comprised of plasma, blood cells, and platelets, is known to exhibit a shear-thinning behavior at low shear rates and near-Newtonian behavior at higher shear rates. However, less is known about the impact of its multiphase nature on the transition to turbulence. In this study, we experimentally determined the critical Reynolds number at which the flow began to transition to turbulence downstream of an eccentric stenosis for whole porcine blood and a Newtonian blood analog (water-glycerin mixture). Velocity profiles for both fluids were measured under steady-state flow conditions using an ultrasound Doppler probe placed 12 diameters downstream of an eccentric stenosis. Velocity was recorded at 21 locations along the diameter at 11 different flow rates. Normalized turbulent kinetic energy was used to determine the critical Reynolds number for each fluid. Blood rheology was measured before and after each experiment. Tests were conducted on five samples of each fluid inside a temperature-controlled in-vitro flow system. The viscosity at shear rate 1000 s 1 was used to define the Reynolds number for each fluid. The mean critical Reynolds numbers for blood and water-glycerin were 470 ± 27.5 and 395 ± 10, respectively, indicating a ~19% delay in transition to turbulence for whole blood compared to the Newtonian fluid. This finding is consistent with a previous report for steady flow in a straight pipe, suggesting some aspect of blood rheology may serve to suppress, or at least delay, the onset of turbulence in vivo.


2021 ◽  
Vol 16 (2) ◽  
Author(s):  
Jiangfeng Guo ◽  
Michael M. B. Ross ◽  
Benedict Newling ◽  
Bruce J. Balcom

1990 ◽  
Vol 112 (4) ◽  
pp. 464-472 ◽  
Author(s):  
D. N. Ku ◽  
C. L. Biancheri ◽  
R. I. Pettigrew ◽  
J. W. Peifer ◽  
C. P. Markou ◽  
...  

Whole body magnetic resonance (MR) imaging has recently become an important diagnostic tool for cardiovascular diseases. The technique of magnetic resonance phase velocity encoding allows the quantitative measurement of velocity for an arbitrary component direction. A study was initiated to determine the ability and accuracy of MR velocimetry to measure a wide range of flow conditions including flow separation, three-dimensional secondary flow, high velocity gradients, and turbulence. A steady flow system pumped water doped with manganese chloride through a variety of test sections. Images were produced using gradient echo sequences on test sections including a straight tube, a curved tube, a smoothly converging-diverging nozzle, and an orifice. Magnetic resonance measurements of laminar and turbulent flows were depicted as cross-sectional velocity profiles. MR velocity measurements revealed such flow behavior as spatially varying velocity, recirculation and secondary flows over a wide range of conditions. Comparisons made with published experimental laser Doppler anemometry measurements and theoretical calculations for similar flow conditions revealed excellent accuracy and precision levels. The successful measurement of velocity profiles for a variety of flow conditions and geometries indicate that magnetic resonance imaging is an accurate, non-contacting velocimeter.


2012 ◽  
Vol 79 (4) ◽  
Author(s):  
Swati Mukhopadhyay ◽  
Kuppalapalle Vajravelu

The effect of transpiration on unsteady two-dimensional flow of an MHD non-Newtonian Maxwell fluid over a stretching surface in the presence of a heat source/sink is investigated. The upper convected Maxwell fluid model is used to characterize the non-Newtonian fluid behavior. Using a similarity transformation the governing partial differential equations of the problem are reduced to a system of ordinary differential equations (ODEs), and the ODEs are solved numerically by a shooting method. The flow features and the heat transfer characteristics are analyzed and discussed in detail for several sets of values of the governing parameters. Though the velocity of the fluid initially decreases with increasing unsteady parameter but it increases finally. Quite the opposite is true with the temperature. Furthermore, the velocity of the fluid decreases with an increasing magnetic or Maxwell parameter. But the temperature is enhanced with an increasing Maxwell parameter. It is observed that the effect of the transpiration is to decrease the fluid velocity as well as the temperature. The results obtained reveal many interesting behaviors that warrant further study of the equations related to non-Newtonian fluid phenomena, especially the shear-thinning phenomena. Shear thinning reduces the wall shear stress.


2012 ◽  
Vol 2012 ◽  
pp. 1-12 ◽  
Author(s):  
Sanehiro Wada ◽  
Kenichi Tezuka ◽  
Weerachon Treenuson ◽  
Nobuyushi Tsuzuki ◽  
Hiroshige Kikura

This paper presents a new estimation method to determine the optimal number of transducers using an Ultrasonic Velocity Profile (UVP) for accurate flow rate measurement downstream of a single elbow. Since UVP can measure velocity profiles over a pipe diameter and calculate the flow rate by integrating these velocity profiles, it is also expected to obtain an accurate flow rate using multiple transducers under nondeveloped flow conditions formed downstream of an elbow. The new estimation method employs a wave number of velocity profile fluctuations along a circle on a pipe cross-section using Fast Fourier Transform (FFT). The optimal number of transducers is estimated based on the sampling theorem. To evaluate this method, a preliminary experiment and numerical simulations using Computational Fluid Dynamics (CFD) are conducted. The evaluating regions of velocity profiles are located at 3 times of a pipe diameter () for the experiment, and 1 and for the simulations downstream of an elbow, respectively. Reynolds numbers for the experiment and simulations are set at and , respectively. These results indicate the efficiency of this new method.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Tiziana Ciano ◽  
Massimiliano Ferrara ◽  
Meisam Babanezhad ◽  
Afrasyab Khan ◽  
Azam Marjani

AbstractThe heat transfer improvements by simultaneous usage of the nanofluids and metallic porous foams are still an attractive research area. The Computational fluid dynamics (CFD) methods are widely used for thermal and hydrodynamic investigations of the nanofluids flow inside the porous media. Almost all studies dedicated to the accurate prediction of the CFD approach. However, there are not sufficient investigations on the CFD approach optimization. The mesh increment in the CFD approach is one of the challenging concepts especially in turbulent flows and complex geometries. This study, for the first time, introduces a type of artificial intelligence algorithm (AIA) as a supplementary tool for helping the CFD. According to the idea of this study, the CFD simulation is done for a case with low mesh density. The artificial intelligence algorithm uses learns the CFD driven data. After the intelligence achievement, the AIA could predict the fluid parameters for the infinite number of nodes or dense mesh without any limitations. So, there is no need to solve the CFD models for further nodes. This study is specifically focused on the genetic algorithm-based fuzzy inference system (GAFIS) to predict the velocity profile of the water-based copper nanofluid turbulent flow in a porous tube. The most intelligent GAFIS could perform the most accurate prediction of the velocity. Hence, the intelligence of GAFIS is tested for different values of cluster influence range (CIR), squash factor(SF), accept ratio (AR) and reject ratio (RR), the population size (PS), and the percentage of crossover (PC). The maximum coefficient of determination (~ 0.97) was related to the PS of 30, the AR of 0.6, the PC of 0.4, CIR of 0.15, the SF 1.15, and the RR of 0.05. The GAFIS prediction of the fluid velocity was in great agreement with the CFD. In the most intelligent condition, the velocity profile predicted by GAFIS was similar to the CFD. The nodes increment from 537 to 7671 was made by the GAFIS. The new predictions of the GAFIS covered all CFD results.


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