Graphical Hopf Bifurcation of a Filippov HTLV-1 Model With Delay in Cytotoxic T Cells Response

2018 ◽  
Vol 140 (9) ◽  
Author(s):  
Elham Shamsara ◽  
Zahra Afsharnezhad ◽  
Elham Javidmanesh

In this paper, we present a discontinuous cytotoxic T cells (CTLs) response for HTLV-1. Moreover, a delay parameter for the activation of CTLs is considered. In fact, a system of differential equation with discontinuous right-hand side with delay is defined for HTLV-1. For analyzing the dynamical behavior of the system, graphical Hopf bifurcation is used. In general, Hopf bifurcation theory will help to obtain the periodic solutions of a system as parameter varies. Therefore, by applying the frequency domain approach and analyzing the associated characteristic equation, the existence of Hopf bifurcation by using delay immune response as a bifurcation parameter is determined. The stability of Hopf bifurcation periodic solutions is obtained by the Nyquist criterion and the graphical Hopf bifurcation theorem. At the end, numerical simulations demonstrated our results for the system of HTLV-1.

2007 ◽  
Vol 17 (04) ◽  
pp. 1355-1366 ◽  
Author(s):  
WENWU YU ◽  
JINDE CAO

In this paper, a general two-neuron model with time delay is considered, where the time delay is regarded as a parameter. It is found that Hopf bifurcation occurs when this delay passes through a sequence of critical value. By analyzing the characteristic equation and using the frequency domain approach, the existence of Hopf bifurcation is determined. The stability of bifurcating periodic solutions are determined by the harmonic balance approach, Nyquist criterion and the graphic Hopf bifurcation theorem. Numerical results are given to justify the theoretical analysis.


2014 ◽  
Vol 2014 ◽  
pp. 1-12 ◽  
Author(s):  
Qingsong Liu ◽  
Yiping Lin ◽  
Jingnan Cao

A modified Leslie-Gower predator-prey system with two delays is investigated. By choosingτ1andτ2as bifurcation parameters, we show that the Hopf bifurcations occur when time delay crosses some critical values. Moreover, we derive the equation describing the flow on the center manifold; then we give the formula for determining the direction of the Hopf bifurcation and the stability of bifurcating periodic solutions. Numerical simulations are carried out to illustrate the theoretical results and chaotic behaviors are observed. Finally, using a global Hopf bifurcation theorem for functional differential equations, we show the global existence of the periodic solutions.


2014 ◽  
Vol 2014 ◽  
pp. 1-12 ◽  
Author(s):  
Xue Zhang ◽  
Qing-ling Zhang ◽  
Zhongyi Xiang

A singular prey-predator model with time delays is formulated and analyzed. Allee effect is considered on the growth of the prey population. The singular prey-predator model is transformed into its normal form by using differential-algebraic system theory. We study its dynamics in terms of local analysis and Hopf bifurcation. The existence of periodic solutions via Hopf bifurcation with respect to two delays is established. In particular, we study the direction of Hopf bifurcation and the stability of bifurcated periodic solutions by applying the normal form theory and the center manifold argument. Finally, numerical simulations are included supporting the theoretical analysis and displaying the complex dynamical behavior of the model outside the domain of stability.


2005 ◽  
Vol 15 (05) ◽  
pp. 1589-1601 ◽  
Author(s):  
SHAOWEN LI ◽  
XIAOFENG LIAO ◽  
CHUNGUANG LI ◽  
KWOK-WO WONG

In this paper, a two-neuron network with different time delays is investigated. By analyzing the associated characteristic equation, we obtain the conditions for delay-dependent and delay-independent asymptotic stability, respectively. Furthermore, we find that if the delay is used as a bifurcation parameter, Hopf bifurcation would occur. The direction and stability of the bifurcating periodic solutions are determined by using the Nyquist criterion and the graphical Hopf bifurcation theorem. Some examples are included to illustrate our results.


2017 ◽  
Vol 2017 ◽  
pp. 1-14
Author(s):  
Hongwei Luo ◽  
Jiangang Zhang ◽  
Wenju Du ◽  
Jiarong Lu ◽  
Xinlei An

A PI hydroturbine governing system with saturation and double delays is generated in small perturbation. The nonlinear dynamic behavior of the system is investigated. More precisely, at first, we analyze the stability and Hopf bifurcation of the PI hydroturbine governing system with double delays under the four different cases. Corresponding stability theorem and Hopf bifurcation theorem of the system are obtained at equilibrium points. And then the stability of periodic solution and the direction of the Hopf bifurcation are illustrated by using the normal form method and center manifold theorem. We find out that the stability and direction of the Hopf bifurcation are determined by three parameters. The results have great realistic significance to guarantee the power system frequency stability and improve the stability of the hydropower system. At last, some numerical examples are given to verify the correctness of the theoretical results.


2021 ◽  
Vol 31 (08) ◽  
pp. 2150143
Author(s):  
Zunxian Li ◽  
Chengyi Xia

In this paper, we explore the dynamical behaviors of the 1D two-grid coupled cellular neural networks. Assuming the boundary conditions of zero-flux type, the stability of the zero equilibrium is discussed by analyzing the relevant eigenvalue problem with the aid of the decoupling method, and the conditions for the occurrence of Turing instability and Hopf bifurcation at the zero equilibrium are derived. Furthermore, the approximate expressions of the bifurcating periodic solutions are also obtained by using the Hopf bifurcation theorem. Finally, numerical simulations are provided to demonstrate the theoretical results.


2018 ◽  
Vol 28 (09) ◽  
pp. 1850109 ◽  
Author(s):  
Xiangming Zhang ◽  
Zhihua Liu

We make a mathematical analysis of an age structured HIV infection model with both virus-to-cell and cell-to-cell transmissions to understand the dynamical behavior of HIV infection in vivo. In the model, we consider the proliferation of uninfected CD[Formula: see text] T cells by a logistic function and the infected CD[Formula: see text] T cells are assumed to have an infection-age structure. Our main results concern the Hopf bifurcation of the model by using the theory of integrated semigroup and the Hopf bifurcation theory for semilinear equations with nondense domain. Bifurcation analysis indicates that there exist some parameter values such that this HIV infection model has a nontrivial periodic solution which bifurcates from the positive equilibrium. The numerical simulations are also carried out.


2018 ◽  
Vol 28 (11) ◽  
pp. 1850136 ◽  
Author(s):  
Ben Niu ◽  
Yuxiao Guo ◽  
Yanfei Du

Tumor-immune interaction plays an important role in the tumor treatment. We analyze the stability of steady states in a diffusive tumor-immune model with response and proliferation delay [Formula: see text] of immune system where the immune cell has a probability [Formula: see text] in killing tumor cells. We find increasing time delay [Formula: see text] destabilizes the positive steady state and induces Hopf bifurcations. The criticality of Hopf bifurcation is investigated by deriving normal forms on the center manifold, then the direction of bifurcation and stability of bifurcating periodic solutions are determined. Using a group of parameters to simulate the system, stable periodic solutions are found near the Hopf bifurcation. The effect of killing probability [Formula: see text] on Hopf bifurcation values is also discussed.


2014 ◽  
Vol 2014 ◽  
pp. 1-8
Author(s):  
Yuanyuan Chen ◽  
Ya-Qing Bi

A delay-differential modelling of vector-borne is investigated. Its dynamics are studied in terms of local analysis and Hopf bifurcation theory, and its linear stability and Hopf bifurcation are demonstrated by studying the characteristic equation. The stability and direction of Hopf bifurcation are determined by applying the normal form theory and the center manifold argument.


2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Jianming Zhang ◽  
Lijun Zhang ◽  
Chaudry Masood Khalique

The dynamics of a prey-predator system with a finite delay is investigated. We show that a sequence of Hopf bifurcations occurs at the positive equilibrium as the delay increases. By using the theory of normal form and center manifold, explicit expressions for determining the direction of the Hopf bifurcations and the stability of the bifurcating periodic solutions are derived.


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