Changes in Bone Mineral Density and Mechanical Properties Due to Alcohol and Ovariectomy in Trabecular Bone of Female Rats

2002 ◽  
Author(s):  
Harry A. Hogan ◽  
H. Wayne Sampson
Keyword(s):  
Mechanical Properties ◽  
Bone Mineral Density ◽  
Animal Model ◽  
Risk Factor ◽  
Alcohol Consumption ◽  
Trabecular Bone ◽  
Bone Mineral ◽  
Female Rats ◽  
Mineral Density ◽  
Rat Animal Model

Alcohol consumption is a known risk factor exacerbating postmenopausal osteoporosis [1,2]. The current study was undertaken to investigate these effects using the rat animal model. Recent studies with rats have shown deleterious effects due to alcohol [3,4], but no significant effects when combined estrogen deficiency induced by ovariectomy (OVX) [5]. This last study did not report mechanical properties, however. The objective of the current study was to investigate the effects of alcohol and OVX on trabecular bone mechanical properties and bone mineral density (BMD) in adult female rats. An important issue in evaluating osteoporosis and related bone maladies clinically is the relation between bone mineral density (BMD) and fracture risk or incidence. Thus, an additional goal of the current study was to examine the relationships (correlations) between trabecular bone BMD and mechanical properties.

scholarly journals Evaluation of association of fragility fracture and bone mineral density in Nepalese population

2013 ◽  
Vol 2 (2) ◽  
pp. 130-134
Author(s):  
Md. Farid Amanullah ◽  
BP Shrestha ◽  
GP Khanal ◽  
NK Karna ◽  
S Ansari ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Risk Factor ◽  
Alcohol Consumption ◽  
Bone Mineral ◽  
Fragility Fracture ◽  
High Energy ◽  
Medical Illness ◽  
Mineral Density ◽  
T Score ◽  
Study Results

Background: Fragility fractures are one of the major health problems. Many factors are associated with it some of which are modifiable and some are not. If we know the value of T-score at which fragility fracture occurs and associated factors responsible for fragility fracture than we will be able to control this burden to the society. The objective of this study is to determine association between fragility fracture and bone mineral density (BMD) using bone densitometry and to know the value of T-score at which fragility fracture occurs. Methods: Patients presenting to B.P. Koirala Institute of Health Sciences with fragility fracture of distal end of radius, fracture around hip and vertebral fractures were included in the study to know the value of T-score at which fragility fracture occurs and their associated risk factor. Patients less than 50 years of age, high energy trauma fracture and pathological fractures were excluded from the study. Results: We found that being multipara, smoking, alcohol consumption, post-hysterectomized patients and steroid intake had significant association with fragility fracture. There was no association with religion, geographic location, associated medical illness, age, sex, associated injury and site of injury. Conclusion: The patients with risk factor for fragility fracture like smoking, alcohol consumption, multipara women, post-hysterectomized women and those who are on long term steroid therapy should undergo BMD test and the value at -3.254 are prone to fragility fracture and should be treated accordingly. Nepal Journal of Medical Sciences | Volume 02 | Number 02 | July-December 2013 | Page 130-134 DOI: http://dx.doi.org/10.3126/njms.v2i2.8956

scholarly journals Comparison of in Vitro Young and Old Lumbar Vertebrae of Ewes Related to Bone Density and Compression Strength

2017 ◽  
Vol 11 (4) ◽  
pp. 65 ◽  
Author(s):  
Sahar Ahmed Abdalbary ◽  
Sherif Mamdouh Amr
Keyword(s):  
Mechanical Properties ◽  
Bone Mineral Density ◽  
Animal Model ◽  
Bone Mineral ◽  
Lumbar Vertebrae ◽  
Compressive Force ◽  
Fixation Strength ◽  
Mineral Density ◽  
Orthopedic Device

An animal model (the ewe) was used to study the mechanical properties of lumbar vertebrae and to compare these properties with the bone mineral density. We measured the bone mineral density for lumbar vertebrae of 10 ewes for L2 & L5 for5 young ewes mean age 2 years and 5 old ewes mean age 8 years old. Compression test was conducted on ewes lumbar vertebrae L2 & l5 for young ewes and old ewes.There was significance differences between both group related to bone mineral density , compressive force , and young’s modulus. There was strong correlation between the mechanical properties and bone mineral density.Bone mineral density correlated with the mechanical properties and it is not surprising that an orthopedic device used with poorly mineralized bone can have lower mechanical fixation strength than the same device with well-mineralized bone.

scholarly journals Trabecular Bone Score Could Not Predict the Bone Mineral Density of Proximal Humerus

2021 ◽  
Vol 28 (3) ◽  
pp. 239-247
Author(s):  
Hyeon Jang Jeong ◽  
Joong Mo Ahn ◽  
Joo Han Oh
Keyword(s):  
Bone Mineral Density ◽  
Risk Factor ◽  
Trabecular Bone ◽  
Direct Measurement ◽  
Bone Mineral ◽  
Proximal Humerus ◽  
Trabecular Bone Score ◽  
Tendon Healing ◽  
Mineral Density ◽  
Clinical Factor

Background: Osteoporosis is an important clinical factor for tendon healing after arthroscopic rotator cuff repair (ARCR). Conventional dual energy X-ray absorptiometry (DXA) of the hip and lumbar spine (LS) does not represent proximal humeral bone mineral density (BMD). Theoretically, direct measurement of the BMD of the proximal humerus is the best method; however, it is not popular and is non-standardized. Therefore, we evaluate whether the trabecular bone score (TBS) using LS DXA would represent proximal humeral BMD.Methods: Conventional hip and LS DXA and proximal humeral BMD were measured in 212 consecutive ARCR patients, and TBS was calculated using LS DXA. Comparative analysis between the affected and contralateral asymptomatic shoulders was done; moreover, correlation analysis was conducted to evaluate the representativity of TBS for proximal humeral BMD. Regression analysis was performed to elucidate the risk factor of intraoperative suture anchor failure (ISAF).Results: BMDs of the affected shoulder were significantly lower than those of the contralateral side (all P<0.05). TBS failed to present a strong correlation with proximal humeral BMD (correlation coefficients 0.155-0.506, all P<0.05), and the BMD of the greater tuberosity (GT) of the proximal humerus was revealed to be a sole risk factor for ISAF (odds ratio, 0.01, P=0.020).Conclusions: TBS and conventional hip and LS DXA did not represent proximal humeral BMD. Furthermore, among the various radiological measurements, the BMD of the GT was a sole risk factor of ISAF. Therefore, further research for the direct measurement of proximal humeral BMD is mandatory to predict proximal humeral focal osteoporosis.

VALIDATION OF THE USE OF FRACTIONAL QUANTITATIVE COMPUTED TOMOGRAPHY BASED ON THE MECHANICAL PROPERTIES OF TRABECULAR BONE

2010 ◽  
Vol 24 (15n16) ◽  
pp. 2670-2675
Author(s):  
JONG MIN LEE ◽  
YONG MIN CHANG ◽  
GUANG HU JIN ◽  
JONG HYOUNG KIM ◽  
CHANG MIN SUH
Keyword(s):  
Computed Tomography ◽  
Mechanical Properties ◽  
Bone Mineral Density ◽  
Compressive Strength ◽  
Trabecular Bone ◽  
Bone Mineral ◽  
Quantitative Computed Tomography ◽  
Mineral Density

The fractional quantitative computed tomography (fQCT) to determine both quantity and distribution of bone mineral was evaluated based on the mechanical properties of trabecular bone. Using quantitative computed tomography (QCT), bone mineral density was measured at 46 areas from 5 bovine tibias. Subsequently, fQCT was measured by the proportion of pixels showing a bone mineral density greater than 290 mg/ml. Based on the mechanical properties of the bone specimens, the QCT and the fQCT were compared. The fQCT showed a significant correlation with the compressive strength with superiority to the QCT.

Abstract #225 Trabecular Bone Score is Lower in Patients on Permanent Hemodialysis Compared to Controls Matched for Bone Mineral Density

2019 ◽  
Vol 25 ◽  
pp. 77-78
Author(s):  
Roxana Dusceac ◽  
Dan Niculescu ◽  
Madalina Sorohan ◽  
Ramona Dobre ◽  
Catalina Poiana
Keyword(s):  
Bone Mineral Density ◽  
Trabecular Bone ◽  
Bone Mineral ◽  
Trabecular Bone Score ◽  
Mineral Density

Inadequate vitamin D status adversely affects trabecular bone mineral density in 14-18 year old adolescents

2017 ◽  
Author(s):  
Taryn Smith ◽  
Laura Tripkovic ◽  
Camilla Damsgaard ◽  
Christian Molgaard ◽  
Aine Hennessy ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Vitamin D ◽  
Trabecular Bone ◽  
Bone Mineral ◽  
Vitamin D Status ◽  
Mineral Density ◽  
Trabecular Bone Mineral Density
Sign in / Sign up

Export Citation Format

Share Document