scholarly journals Comparison of in Vitro Young and Old Lumbar Vertebrae of Ewes Related to Bone Density and Compression Strength

2017 ◽  
Vol 11 (4) ◽  
pp. 65 ◽  
Author(s):  
Sahar Ahmed Abdalbary ◽  
Sherif Mamdouh Amr

An animal model (the ewe) was used to study the mechanical properties of lumbar vertebrae and to compare these properties with the bone mineral density. We measured the bone mineral density for lumbar vertebrae of 10 ewes for L2 & L5 for5 young ewes mean age 2 years and 5 old ewes mean age 8 years old. Compression test was conducted on ewes lumbar vertebrae L2 & l5 for young ewes and old ewes.There was significance differences between both group related to bone mineral density , compressive force , and young’s modulus. There was strong correlation between the mechanical properties and bone mineral density.Bone mineral density correlated with the mechanical properties and it is not surprising that an orthopedic device used with poorly mineralized bone can have lower mechanical fixation strength than the same device with well-mineralized bone.

2017 ◽  
Vol 20 (2) ◽  
pp. 205-215 ◽  
Author(s):  
Louise V. Coutts ◽  
Thomas Jenkins ◽  
Richard O.C. Oreffo ◽  
Doug G. Dunlop ◽  
Cyrus Cooper ◽  
...  

Author(s):  
Harry A. Hogan ◽  
H. Wayne Sampson

Alcohol consumption is a known risk factor exacerbating postmenopausal osteoporosis [1,2]. The current study was undertaken to investigate these effects using the rat animal model. Recent studies with rats have shown deleterious effects due to alcohol [3,4], but no significant effects when combined estrogen deficiency induced by ovariectomy (OVX) [5]. This last study did not report mechanical properties, however. The objective of the current study was to investigate the effects of alcohol and OVX on trabecular bone mechanical properties and bone mineral density (BMD) in adult female rats. An important issue in evaluating osteoporosis and related bone maladies clinically is the relation between bone mineral density (BMD) and fracture risk or incidence. Thus, an additional goal of the current study was to examine the relationships (correlations) between trabecular bone BMD and mechanical properties.


2017 ◽  
Vol 28 (4) ◽  
pp. 1461-1471 ◽  
Author(s):  
R . Okubo ◽  
L. S. Sanada ◽  
V. A. Castania ◽  
M. J. Q. Louzada ◽  
F. J. A. de Paula ◽  
...  

Author(s):  
Yener N. Yeni ◽  
Laila M. Poisson ◽  
Michael J. Flynn

Bone qualities that are measurable via clinically available modalities and that can explain fracture risk beyond what is explainable by bone mineral density (BMD) are of significant interest. Evidence from literature suggests that the heterogeneity of BMD within a vertebra, in addition to the average BMD, may be an important determinant of the mechanical properties of a vertebra 1–3 and risk of a clinical vertebral fracture 4. Much of the experimental evidence comes from tests, in which vertebrae are monotonically loaded and relates BMD heterogeneity to the quasi-static properties of a vertebra 1, 3. The appearance of clinical vertebral fractures is in the form of progressive deformities indicating that fatigue processes are involved. However, the relationships between BMD heterogeneity and fatigue properties of a vertebra are not well-understood.


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