A Relationship Between Pressure Fields and Flow Patterns During Left Ventricular Diastolic Dysfunction Using 2D Phase Contrast MRI

2010 ◽  
Author(s):  
John J. Charonko ◽  
Rahul Kumar ◽  
Kelley Stewart ◽  
William C. Little ◽  
Pavlos P. Vlachos
Keyword(s):  
Diastolic Dysfunction ◽  
Phase Contrast ◽  
Early Stage ◽  
The United States ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
The Body ◽  
Compensatory Mechanisms ◽  
Pressure Fields ◽  
Ventricular Diastolic Dysfunction

Left Ventricular Diastolic Dysfunction (LVDD) is a disease in which the heart is unable to properly fill the left ventricle before the systolic contraction pushes the blood out of the chamber into the rest of the body [1]. It is frequently characterized by elevated filling pressures within the heart. Over 70 million people in the United States with high blood pressure are at risk for LVDD [2], and numerous studies have shown a link between LVDD and heart failure. However, due to compensatory mechanisms early stage dysfunction can be difficult to diagnose.

Investigation of the Relationship Between Color M-Mode Early Diastolic Propagation Velocity and Left Ventricular Adverse Pressure Gradients

2010 ◽  
Author(s):  
Kelley C. Stewart ◽  
Rahul Kumar ◽  
John J. Charonko ◽  
Pavlos P. Vlachos ◽  
William C. Little
Keyword(s):  
Heart Failure ◽  
Diastolic Dysfunction ◽  
Diastolic Heart Failure ◽  
Diagnostic Techniques ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
Pressure Gradients ◽  
Compensatory Mechanisms ◽  
Ventricular Diastolic Dysfunction ◽  
The Relationship

Left ventricular diastolic dysfunction (LVDD) and diastolic heart failure are conditions that affect the filling dynamics of the heart and affect 36% of patients diagnosed with congestive heart failure [1]. Although this condition is very prevalent, it currently remains difficult to diagnose due to inherent atrio-ventricular compensatory mechanisms including increased heart rate, increased left ventricular (LV) contractility, and increased left atrial pressure (LA). A greater comprehension of the governing flow physics in the left ventricle throughout the introduction of the heart’s compensatory mechanisms has great potential to substantially increase the understanding of the progression of diastolic dysfunction and in turn advance the diagnostic techniques.

Left Ventricular Vortex Ring Dynamics and Their Association to Early Diastolic Filling

2011 ◽  
Author(s):  
Kelley C. Stewart ◽  
John J. Charonko ◽  
Takahiro Ohara ◽  
William C. Little ◽  
Pavlos P. Vlachos
Keyword(s):  
Diastolic Dysfunction ◽  
Left Atrial ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
Diastolic Filling ◽  
Compensatory Mechanisms ◽  
Ring Dynamics ◽  
Ventricular Diastolic Dysfunction ◽  
Ventricular Filling ◽  
Early Filling

Diastolic dysfunction is the impairment of the filling in the left ventricle. Patients with left ventricular diastolic dysfunction (LVDD) lose the ability to adjust left ventricular filling properties without increasing left atrial pressure [1]. Although LVDD is very prevalent, it currently remains difficult to diagnose due to inherent atrioventricular compensatory mechanisms including increased heart rate, increased left ventricular (LV) contractility, and increased left atrial (LA) pressure. Although variations within the early diastolic filling velocity have been previously observed [2], the physical mechanism for the deceleration of the early filling wave is not understood.

1175: Left Ventricular Diastolic Dysfunction in the Early Stage of Chronic Kidney Disease

2009 ◽  
Vol 35 (8) ◽  
pp. S146
Author(s):  
Takenori Otsuka ◽  
Makoto Suzuki ◽  
Hisao Yoshikawa ◽  
Tsukasa Osaki ◽  
Takako Tsuchida ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Diastolic Dysfunction ◽  
Early Stage ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
Ventricular Diastolic Dysfunction

scholarly journals Detection of Left Ventriculer Diastolic Dysfunction (LVDD) in Asymptomatic, Normotensive, ETT Negative Newly Detected Type-2 Diabetic Patients by Doppler Echocardiography

2004 ◽  
Vol 3 (3) ◽  
pp. 36-37
Author(s):  
SK Banerjee ◽  
MA Siddique ◽  
MA Siddique ◽  
CM Ahmed ◽  
AA Jamil ◽  
...  
Keyword(s):  
Diastolic Dysfunction ◽  
Early Stage ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Ventricular Diastolic Dysfunction ◽  
Type 2 Diabetic ◽  
Early Manifestation

Left ventricular diastolic dysfunction (LVDD) is the early manifestation of diabetic Cardiomyopathy, which is most often asymptomatic in early stage.

A Novel Break Point Parameter as a Diagnostic Tool for Left Ventricular Diastolic Dysfunction

2008 ◽  
Author(s):  
Kelley C. Stewart ◽  
Rahul Kumar ◽  
John J. Charonko ◽  
Pavlos P. Vlachos ◽  
William C. Little
Keyword(s):  
Cardiovascular Disease ◽  
Diastolic Dysfunction ◽  
Causes Of Death ◽  
Break Point ◽  
The United States ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
Diagnostic Tools ◽  
Ventricular Diastolic Dysfunction ◽  
Point Parameter

Cardiovascular disease is one of the leading causes of death worldwide and claims one out of every three deaths in the United States [1]. There is a greater need than ever for more accurate and robust diagnostic tools with the increasing number of deaths caused by this disease. Color M-mode echocardiography is a technique that is commonly used in the diagnosis of Left Ventricular Diastolic Dysfunction (LVDD).

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