scholarly journals The Role of Experimental Work

1962 ◽  
Vol 30 (3) ◽  
pp. 186-190 ◽  
Author(s):  
H. V. Neher
Keyword(s):  
2019 ◽  
Vol 7 (1) ◽  
pp. 10-18
Author(s):  
Tsvetanka Tsenova

This article focuses on the relationship between literacy methods applied at school and the emergence of serious difficulties in mastering reading and writing skills that shape the developmental dyslexia. The problem was analyzed theoretically and subjected to empirical verification. Experimental work was presented which aims to study the phonological and global reading skills of 4- th grade students with and without dyslexia. Better global reading skills have been demonstrated in all tested children, and this is much more pronounced in those with dyslexia than their peers without disorders. Hence, the need to develop a special, corrective methodology for literacy of students with developmental dyslexia consistent with their psychopathological characteristics.


2004 ◽  
Vol 14 (02) ◽  
pp. 453-491 ◽  
Author(s):  
EROL BAŞAR ◽  
MURAT ÖZGÖREN ◽  
SIREL KARAKAŞ ◽  
CANAN BAŞAR-EROĞLU

The present report describes the dynamic foundations of long-standing experimental work in the field of oscillatory dynamics in the human and animal brain. It aims to show the role of multiple oscillations in the integrative brain function, memory, and complex perception by a recently introduced conceptional framework: the super-synergy in the whole brain. Results of recent experiments related to the percept of the grandmother-face support our concept of super-synergy in the whole brain in order to explain manifestation of Gestalts and Memory-Stages. This report may also provide new research avenues in macrodynamics of the brain.


2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Oliver Zimmermann ◽  
Kefei Li ◽  
Myron Zaczkiewicz ◽  
Matthias Graf ◽  
Zhongmin Liu ◽  
...  

The role of C-reactive protein (CRP) in atherosclerosis is controversially discussed. Whereas initial experimental studies suggested a pathogenic role for CRP in atherogenesis, more recent genetic data from Mendelian randomization trials failed to provide evidence for a causative role of CRP in cardiovascular disease. Also, experimental results from laboratories all over the world were indeed contradictory, partly because of species differences in CRP biology and partly because data were not accurately evaluated. Here we summarize the published data from experimental work with mainly human material in order to avoid confusion based on species differences in CRP biology. Experimental work needs to be reevaluated after reconsideration of some traditional rules in research: (1) in order to understand a molecule’s role in disease it may be helpful to be aware of its role in physiology; (2) it is necessary to define the disease entity that experimental CRP research deals with; (3) the scientific consensus is as follows: do not try to prove your hypothesis. Specific CRP inhibition followed by use of CRP inhibitors in controlled clinical trials may be the only way to prove or disprove a causative role for CRP in cardiovascular disease.


2021 ◽  
Author(s):  
Shivansh Shrivastava ◽  
Michael Stewardson ◽  
Meenakshi Arora

<p>In-stream faunal organisms constantly interact with their habitat to modify its physical and hydraulic properties. However, little is known about how sediment-organism interactions could modify the hyporheic exchange. Previous experimental work investigating the effects of the activities of faunal organisms on exchange across the sediment-water interface has been largely conducted in small mesocosms or infiltration columns that do not represent the lotic environment adequately. Therefore, the experimental findings from these studies may not be transferable to flowing water environments (e.g., streams). Our previous experimental work demonstrated that sediment reworking by macroinvertebrates could significantly alter the hyporheic flux, mean residence times, and depth of exchange in streambeds. In this work, we explore how sediment-organism contact time influence the effect of the activities of model organisms, Lumbriculus variegatus, on the hyporheic flow regime. We conduct laboratory experiments in re-circulating flumes subject to different sediment reworking times (5 and 10 days). The hyporheic flow characteristics in these flumes were studied by conducting dye tracer tests after the bed sediments were reworked. Deposition of fecal pellets and holes/burrows dug by sample organisms were visible at the bed surface in both the experimental flumes. The flume reworked for a longer time exhibited higher hyporheic flux, longer median/mean residence times, and deeper depth of solute penetration compared to the flume reworked for a shorter period. The modification of hyporheic flow regime to different degrees depending on the sediment reworking times has direct relevance to the biogeochemistry in hyporheic zones, and thus on the overall quality of surface and sub-surface waters. We advocate that more intensive laboratory experiments and field investigations must be conducted to support the findings from our study and advance our understanding of the role of the activities of faunal organisms on fluvial ecosystem functioning.</p>


RSC Advances ◽  
2015 ◽  
Vol 5 (82) ◽  
pp. 66727-66737 ◽  
Author(s):  
O. Ershova ◽  
J. Kanervo ◽  
S. Hellsten ◽  
H. Sixta

An experimental work has been performed to study the relevance of xylulose as an intermediate during non-catalyzed and acid-catalyzed xylose conversions to furfural in aqueous solution at the temperature range from 180 to 220 °C.


1991 ◽  
Vol 7 (2) ◽  
pp. 89-102 ◽  
Author(s):  
Jacquelyn Schachter

In this paper, pedagogical, linguistic theoretical, and psychological perspec tives on corrective feedback are discussed and an attempt is made to inte grate these different perspectives. To a large extent, researchers in these three approaches have been isolated from one another, each ignorant of the others' stands on the issues. Herein, we attempt to overcome the isolation, interweaving the similarities and pointing out the differences of the three approaches. It is argued that the answers to questions raised here and elsewhere concerning the role of corrective feedback in language learning will not come in the form of sweeping affirmative or negative generalizations. They will come from the careful teasing apart of the components of language and experimental work on these components. We need to ascertain whether some components can in fact be acquired on the basis of positive evidence alone, and whether negative evidence (feedback) is required for successful mastery of some other components.


1978 ◽  
Vol 42 (321) ◽  
pp. 1-17 ◽  
Author(s):  
Ian Parsons

SummaryAlkali feldspars in plutonic igneous rocks vary both in their exsolution textures and in the structural state of their components. The primary factor leading to this diversity is the availability of hydrothermal fluids during their cooling history. In many plutons feldspar variation is related to degree of fractionation as indicated by rock chemistry. The variation reflects build-up of water with magmatic evolution and implies that fluids did not circulate freely in the intrusives in the temperature range of unmixing and ordering. Experimental work bearing on the role of fluids in subsolidus changes in feldspars is reviewed, and points of overlap between crystallographic studies of feldspars and stable isotope studies are discussed.


Author(s):  
Catherine M Jackson

Historians have generally confined Liebig's students and assistants to a peripheral role in the development of his Giessen laboratory. This paper argues that these young chemists were essential to Liebig's early success, fulfilling his need for experimental work and producing the apparently independent publications which established the credibility of his new method of organic analysis. Liebig's students and assistants embodied a particular solution to the provision of technician labour and they show us that the technician's role vastly transcends the merely manipulative. The technician, just as much as the scientist, has a history—albeit one that remains largely untold.


2005 ◽  
Vol 39 (7) ◽  
pp. 558-564 ◽  
Author(s):  
Sean D. Hood ◽  
Caroline J. Bell ◽  
David J. Nutt

Objective: Acute tryptophan depletion (ATD) is an experimental technique that has been widely used over the last decade to investigate the role of serotonin (5-HT) in a variety of disorders. This review, the first of two articles, describes the rationale behind this technique and provides detail on how it is applied in research settings. Method: The authors outline the development of this technique with reference to the seminal literature and more recent findings from neuroimaging and neuroendocrine studies. This is supplemented by the authors' clinical experience of over 5 years of continuous experimental work with this paradigm in over 50 subjects. Results: Acute tryptophan depletion is a method that significantly reduces central 5-HT in human subjects. Non-serotonergic explanations of the effects of ATD have not been confirmed, supporting the specificity of this method. Conclusions: The ATD technique is a valid method of manipulating central 5-HT levels. The second article in this series will review the application of ATD in depression, anxiety and other psychiatric conditions.


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