“Because I know It will!”: Placebo Effects of an Ergogenic Aid on Athletic Performance

2007 ◽  
Vol 29 (3) ◽  
pp. 382-394 ◽  
Author(s):  
Mary McClung ◽  
Dave Collins
Keyword(s):  
Drug Use ◽  
Sodium Bicarbonate ◽  
Athletic Performance ◽  
High Performance ◽  
Ergogenic Aids ◽  
Placebo Effects ◽  
Expectancy Effects ◽  
Diverse Range ◽  
Significant Performance ◽  
The Impact

In the perpetual quest for better performance, athletes are using an increasingly diverse range of ergogenic aids. Some are permitted; however, this “drug” use is often seen as an ethically questionable behavior. A variety of research suggests that much of the impact of such aids may be due to expectancy—the belief that the substance will aid performance. It would be useful to demonstrate this to athletes considering such usage, especially as a pillar of antidrug education. Accordingly, this investigation used sodium bicarbonate and placebo additives in a double disassociation design, with athletes completing a series of 1,000-m time trials. Results showed that believing one had taken the substance resulted in times almost as fast as those associated with consuming the drug itself. In contrast, taking the drug without knowledge yielded no significant performance increment. Results are discussed against the backdrop of applying expectancy effects in high-performance sport, including dissuading athletes from using illegal aids.

scholarly journals Expectancy effects threaten the inferential validity of synchrony-prosociality research

2020 ◽  
Author(s):  
S. Atwood ◽  
Samuel A Mehr ◽  
Adena Schachner
Keyword(s):  
A Priori ◽  
Large Body ◽  
Placebo Effects ◽  
Expectancy Effects ◽  
Original Experiment ◽  
Prosocial Attitudes ◽  
Experimenter Expectancy ◽  
And Behavior ◽  
Attitudes And Behavior ◽  
The Impact

A large body of theoretical and experimental work has argued that synchronized movement among people increases prosocial attitudes and behavior. Here we review prior and new evidence that reported effects of synchrony may be driven by experimenter expectancy, leading to experimenter bias; and participant expectancy, otherwise known as placebo effects. To test for the possibility of placebo effects, we asked whether participants have a priori expectations about synchrony and prosociality that match the findings in published literature. In a preregistered experiment, we asked undergraduates (N = 216) to imagine they participated in a synchrony experiment and then predict how they would feel and act afterward. The imagined experiment and the measures of their feelings and actions were taken from a highly cited experiment on synchrony. Even without experiencing an actual synchrony manipulation, participants’ expectations about the effects of synchrony on prosocial attitudes closely matched the actual effects of synchrony reported in the original experiment. The participants who imagined synchronizing expected to feel greater levels of connection, trust, same team feeling, and similarity to their partner, but not greater happiness, than the participants who imagined action that was not synchronized. These expectations (both positive and null) directly mirror reported effects of synchrony, raising the possibility that the synchrony-prosociality literature is vulnerable to placebo effects. Previously reported effects may reflect participants’ top-down expectations about synchrony, rather than the impact of experience with synchrony itself.

Dietary Vitamin and Stability of Oral Anticoagulation: Proposal of a Diet with Constant Vitamin K1 Content

1997 ◽  
Vol 77 (03) ◽  
pp. 504-509 ◽  
Author(s):  
Sarah L Booth ◽  
Jacqueline M Charnley ◽  
James A Sadowski ◽  
Edward Saltzman ◽  
Edwin G Bovill ◽  
...  
Keyword(s):  
Dietary Intake ◽  
Vitamin K ◽  
High Performance ◽  
Case Reports ◽  
Food Composition ◽  
Dietary Guidelines ◽  
Dietary Vitamin ◽  
Vitamin K1 ◽  
The Stability ◽  
The Impact

SummaryCase reports cited in Medline or Biological Abstracts (1966-1996) were reviewed to evaluate the impact of vitamin K1 dietary intake on the stability of anticoagulant control in patients using coumarin derivatives. Reported nutrient-drug interactions cannot always be explained by the vitamin K1 content of the food items. However, metabolic data indicate that a consistent dietary intake of vitamin K is important to attain a daily equilibrium in vitamin K status. We report a diet that provides a stable intake of vitamin K1, equivalent to the current U.S. Recommended Dietary Allowance, using food composition data derived from high-performance liquid chromatography. Inconsistencies in the published literature indicate that prospective clinical studies should be undertaken to clarify the putative dietary vitamin K1-coumarin interaction. The dietary guidelines reported here may be used in such studies.

Alpha Tocopherol Loaded in Liposome: Preparation, Optimization, Characterization and Sperm Motility Protection

2020 ◽  
Vol 10 (3) ◽  
pp. 228-236 ◽  
Author(s):  
Lamia Taouzinet ◽  
Sofiane Fatmi ◽  
Allaeddine Khellouf ◽  
Mohamed Skiba ◽  
Mokrane Iguer-ouada
Keyword(s):  
Vitamin E ◽  
Sperm Motility ◽  
High Performance ◽  
Positive Impact ◽  
Alpha Tocopherol ◽  
Ethanol Injection ◽  
Liposome Preparation ◽  
Liposome Size ◽  
Optimum Solution ◽  
The Impact

Background: Alpha-tocopherol is a potent antioxidant involved in sperm protection particularly during cryopreservation. However, its poor solubility limits the optimal protection in aqueous solutions. Objective: The aim of this study was to enhance the solubility of α-tocopherol by the use of liposomes. Methods: The experimental approach consisted to load vitamin E in liposomes prepared by ethanol injection method and the optimization carried out by an experimental design. The optimum solution was characterized by high performance liquid chromatography and scanning electron microscope. Finely, the impact on sperm motility protection was studied by the freezing technic of bovine sperm. Results: The optimum solution was obtained when using 10.9 mg/ml of phospholipids, 1.7 mg/ml of cholesterol and 2 mg/ml of vitamin E. The liposome size was 99.86 nm, providing 78.47% of loaded efficiency. The results showed also a significant positive impact on sperm motility after hours of preservation. Conclusion: In conclusion, the current results showed the interest of liposome preparation as an alternative to enhance vitamin E solubility and to protect spermatozoa during cryopreservation.

The Oxford Handbook of Adult Cognitive Disorders

2019 ◽  
Keyword(s):  
Cognitive Impairment ◽  
Cognitive Function ◽  
Neurodevelopmental Disorders ◽  
Brain Aging ◽  
Cognitive Disorders ◽  
Diverse Range ◽  
Medical Specialties ◽  
Psychiatric Illnesses ◽  
Medical Disorders ◽  
The Impact

The prevalence of cognitive impairment caused by neurodegenerative diseases and other neurologic disorders associated with aging is expected to rise dramatically between now and year 2050, when the population of Americans aged 65 or older will nearly double. Cognitive impairment also commonly occurs in other neurologic conditions, as well as in non-neurologic medical disorders (and their treatments), idiopathic psychiatric illnesses, and adult neurodevelopmental disorders. Cognitive impairment can thus infiltrate all aspects of healthcare, making it necessary for clinicians and clinical researchers to have an integrated knowledge of the spectrum of adult cognitive disorders. The Oxford Handbook of Adult Cognitive Disorders is meant to serve as an up-to-date, scholarly, and comprehensive volume covering most diseases, conditions, and injuries resulting in impairments in cognitive function in adults. Topics covered include normal cognitive and brain aging, the impact of medical disorders (e.g., cardiovascular, liver, pulmonary) and psychiatric illnesses (e.g., depression and bipolar disorder) on cognitive function, adult neurodevelopmental disorders (e.g., Down Syndrome, Attention Deficit/Hyperactivity Disorder), as well as the various neurological conditions (e.g., Alzheimer’s disease, chronic traumatic encephalopathy, concussion). A section of the Handbook is also dedicated to unique perspectives and special considerations for the clinicians and clinical researchers, covering topics such as cognitive reserve, genetics, diversity, and neuroethics. The target audience of this Handbook includes: (1) clinicians, particularly psychologists, neuropsychologists, neurologists (including behavioral and cognitive neurologists), geriatricians, and psychiatrists (including neuropsychiatrists), who provide clinical care and management for adults with a diverse range of cognitive disorders; (2) clinical researchers who investigate cognitive outcomes and functioning in adult populations; and (3) graduate level students and post-doctoral trainees studying psychology, clinical neuroscience, and various medical specialties.

scholarly journals Does parental permissiveness toward cigarette smoking and alcohol use influence illicit drug use among adolescents? A longitudinal study in seven European countries

2021 ◽  
Author(s):  
Emina Mehanović ◽  
Federica Vigna-Taglianti ◽  
Fabrizio Faggiano ◽  
Maria Rosaria Galanti ◽  
Barbara Zunino ◽  
...  
Keyword(s):  
Alcohol Use ◽  
Drug Use ◽  
Cigarette Smoking ◽  
Longitudinal Data ◽  
Illicit Drug ◽  
Large Population ◽  
Illicit Drug Use ◽  
European Countries ◽  
The Impact

Abstract Purpose Adolescents’ perceptions of parental norms may influence their substance use. The relationship between parental norms toward cigarette and alcohol use, and the use of illicit substances among their adolescent children is not sufficiently investigated. The purpose of this study was to analyze this relationship, including gender differences, using longitudinal data from a large population-based study. Methods The present study analyzed longitudinal data from 3171 12- to 14-year-old students in 7 European countries allocated to the control arm of the European Drug Addiction Prevention trial. The impact of parental permissiveness toward cigarettes and alcohol use reported by the students at baseline on illicit drug use at 6-month follow-up was analyzed through multilevel logistic regression models, stratified by gender. Whether adolescents’ own use of cigarette and alcohol mediated the association between parental norms and illicit drug use was tested through mediation models. Results Parental permissive norms toward cigarette smoking and alcohol use at baseline predicted adolescents’ illicit drug use at follow-up. The association was stronger among boys than among girls and was mediated by adolescents’ own cigarette and alcohol use. Conclusion Perceived parental permissiveness toward the use of legal drugs predicted adolescents’ use of illicit drugs, especially among boys. Parents should be made aware of the importance of norm setting, and supported in conveying clear messages of disapproval of all substances.

Drug Use in Prison: Patterns, Processes, and Implications for Treatment

1993 ◽  
Vol 23 (1) ◽  
pp. 119-129 ◽  
Author(s):  
James A. Inciardi ◽  
Dorothy Lockwood ◽  
Judith A. Quintan
Keyword(s):  
Drug Use ◽  
Drug Testing ◽  
Research Literature ◽  
Prison Violence ◽  
Patterns Of Use ◽  
Correctional Settings ◽  
Correctional System ◽  
The Impact

Although there seems to be a consensus that “drugs are in every prison,” and that “prison drug use is widespread,” little is really known about the prevalence and patterns of drug use in prison. What appears in the academic and research literature is at best anecdotal, suggesting only that drug use and trafficking exist in correctional settings, and that the control of drugs by inmates is in part related to prison violence. Similarly, press reports descriptive of drug use in prison typically focus on trafficking networks and the complicity of prison personnel, rather than on prevalence and patterns of use. Within this context, this article addresses the nature of drug use in prison, based on systematic interviewing and drug testing in the Delaware correctional system. Some conclusions and implications are offered relative to the impact of prison drug use on corrections-based therapeutic initiatives.

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