scholarly journals Outbreak of OXA-48-Positive Carbapenem-Resistant Klebsiella pneumoniae Isolates in France

2011 ◽  
Vol 55 (5) ◽  
pp. 2420-2423 ◽  
Author(s):  
Gaelle Cuzon ◽  
Jocelyne Ouanich ◽  
Remy Gondret ◽  
Thierry Naas ◽  
Patrice Nordmann
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Klebsiella Pneumoniae ◽  
Molecular Analysis ◽  
Medical Intensive Care Unit ◽  
Content Type ◽  
Carbapenem Resistant ◽  
Single Clone ◽  
Medical Intensive Care

ABSTRACTSeventeenKlebsiella pneumoniaeisolates producing the OXA-48 carbapenemase, obtained from 10 patients hospitalized from April to June 2010, mostly in the medical intensive care unit of the Villeneuve-Saint-Georges Hospital in a suburb of Paris, France, were analyzed. Seven patients were infected, of whom five were treated at least with a carbapenem, and five patients died. Molecular analysis showed that the isolates belonged to a single clone that harbored a 70-kb plasmid carrying theblaOXA-48gene and coproduced CTX-M-15 and TEM-1 β-lactamases. This is the first reported outbreak of OXA-48-producingK. pneumoniaeisolates in France.

scholarly journals Nosocomial Outbreak of Klebsiella pneumoniae Carbapenemase-Producing Klebsiella oxytoca in Austria

2012 ◽  
Vol 56 (4) ◽  
pp. 2158-2161 ◽  
Author(s):  
Martin Hoenigl ◽  
Thomas Valentin ◽  
Gernot Zarfel ◽  
Benjamin Wuerstl ◽  
Eva Leitner ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Klebsiella Pneumoniae ◽  
Medical Intensive Care Unit ◽  
Klebsiella Oxytoca ◽  
Nosocomial Outbreak ◽  
Content Type ◽  
Klebsiella Pneumoniae Carbapenemase ◽  
Medical Intensive Care

ABSTRACTTo date, no outbreak of carbapenemase-producing bacteria has been reported for Austria. While outbreaks ofKlebsiella pneumoniaecarbapenemase (KPC)-producingK. pneumoniaehave been increasingly reported, no outbreak caused by KPC-producingKlebsiella oxytocahas been described yet, to the best of our knowledge. We report an outbreak of KPC-producingK. oxytoca. In 5 months, 31 KPC-producingKlebsiella oxytocastrains were isolated from five patients. All patients were admitted to the same medical intensive care unit in Austria.

scholarly journals Spread of Carbapenem-Resistant Klebsiella pneumoniae in an Intensive Care Unit: A Whole-Genome Sequence-Based Prospective Observational Study

2021 ◽  
Author(s):  
Li Wei ◽  
Linfei Wu ◽  
Hongxia Wen ◽  
Yu Feng ◽  
Shichao Zhu ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Klebsiella Pneumoniae ◽  
Prospective Observational Study ◽  
Opportunistic Pathogen ◽  
Whole Genome Sequence ◽  
Whole Genome ◽  
Content Type ◽  
Carbapenem Resistant ◽  
Human Infections

Klebsiella pneumoniae can be an opportunistic pathogen with the oral cavity and gut the main origin. However, carbapenem-resistant Klebsiella pneumoniae (CRKP) can be found in patient surroundings and is a serious threat for human infections.

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