Antileishmanial Activities of Stearylamine-Bearing Liposomes
2000 ◽
Vol 44
(6)
◽
pp. 1739-1742
◽
Keyword(s):
ABSTRACT Here we report the activity of liposomes comprising egg phosphatidylcholine (PC) and stearylamine (SA) against Leishmania donovani parasites. Both promastigotes and intracellular amastigotes in vitro and in vivo were susceptible to SA-PC liposomes. A single dose of 55 mg of SA-PC liposomes/animal could significantly reduce the hepatic parasite burden by 85 and 68% against recent and established experimental visceral leishmaniasis, respectively, suggesting their strong therapeutic potential.
2016 ◽
Vol 8
(12)
◽
pp. 102
Keyword(s):
2011 ◽
Vol 53
(3)
◽
pp. 129-132
◽
Keyword(s):
2010 ◽
Vol 54
(6)
◽
pp. 2507-2516
◽
1998 ◽
Vol 66
(3)
◽
pp. 1233-1236
◽
2011 ◽
Vol 56
(1)
◽
pp. 432-445
◽