Prevalence of Specific Antibodies to Chlamydia pneumoniae in Korea

To clarify the endemic status of Chlamydia pneumoniaein Korea, the incidence of antibodies in 564 serum samples from healthy individuals, patients with respiratory infection, and cord blood specimens was evaluated. We conclude that C. pneumoniaeinfection is highly endemic in Korea and that this infection is associated with acute respiratory diseases.

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Seroepidemiology of Chlamydia Pneumoniae in Northern Greece

European Journal of Inflammation ◽

10.1177/1721727x0900700303 ◽

2009 ◽

Vol 7 (3) ◽

pp. 139-144

Author(s):

D. Chatzidimitriou ◽

M. Exidari ◽

G. Gioula ◽

P. Papakonstantinou ◽

A. Melidou ◽

...

Keyword(s):

Chlamydia Pneumoniae ◽

The Elderly ◽

Healthy Population ◽

Serum Samples ◽

Igg Antibody ◽

Northern Greece ◽

Specific Antibodies ◽

High Prevalence ◽

Iga Antibodies ◽

One Year

The prevalence of IgG and IgA antibodies to Chlamydia pneumoniae was evaluated in a group of an apparently healthy population in northern Greece. Serum samples were obtained over a period of one year (June 2006 to May 2007) from 530 individuals (300 males and 230 females, aged from 1 month to 90 years). The sera were tested for specific antibodies to C. pneumoniae by two commercial methods, an ELISA and a micro-IF assay based on the principles of MIF. The prevalence of IgG and IgA antibodies to C. pneumoniae was 53.2% and 45.9%, respectively, and was found to be unrelated to gender, even in the elderly >61 years old. The IgG antibody prevalence was low in children under 5 years old (7.7%), sharply increased by the age of 20 (40%) and continued to increase, gradually, to reach 80.1% in the elderly. IgA antibodies also increased with similar kinetics to IgG, although at a lower level (3.8–66.1%). Our results show that infection with C. pneumoniae is common in northern Greece. The high prevalence of IgA specific antibodies reported in the present study is due to primary infection at a young age, while in the elderly is probably due to infection or reinfection, although the option of persistence cannot be excluded.

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TT Virus Loads and Lymphocyte Subpopulations in Children with Acute Respiratory Diseases

Journal of Virology ◽

10.1128/jvi.77.16.9081-9083.2003 ◽

2003 ◽

Vol 77 (16) ◽

pp. 9081-9083 ◽

Cited By ~ 40

Author(s):

Fabrizio Maggi ◽

Massimo Pifferi ◽

Elena Tempestini ◽

Claudia Fornai ◽

Letizia Lanini ◽

...

Keyword(s):

T Cells ◽

Respiratory Diseases ◽

Inverse Correlation ◽

Lymphocyte Subpopulations ◽

Helper T Cells ◽

Plasma Viremia ◽

Healthy Individuals ◽

Human Virus ◽

Tt Virus ◽

Acute Respiratory Diseases

ABSTRACT TT virus (TTV) produces chronic plasma viremia in around 90% of healthy individuals of all ages and has, therefore, been proposed as a commensal human virus. We recently demonstrated that in children hospitalized for acute respiratory diseases high TTV loads were associated with severe forms of disease. Here, we report that in such children TTV loads showed an inverse correlation with the percentage of circulating total T and helper T cells and a direct correlation with the percentage of B cells. Thus, florid TTV replication might contribute to lymphocyte imbalances and, possibly, immunosuppressive effects, thus resembling related animal viruses.

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Seasonal fluctuations C. pneumonia and M. pneumoniae infections among children with acute respiratory diseases

Sanitarnyj vrač (Sanitary Inspector) ◽

10.33920/med-08-2106-01 ◽

2021 ◽

pp. 8-16

Author(s):

Vera A. Kebak ◽

Sergey А. Krotov ◽

Natalia V. Kukhtinova

Keyword(s):

Respiratory Diseases ◽

Community Acquired Pneumonia ◽

School Age Children ◽

School Age ◽

Seasonal Fluctuations ◽

Serum Samples ◽

Epidemic Process ◽

Acute Respiratory Diseases ◽

Peak Increase ◽

Chlamydial Infections

The article presents the results of the analysis of the main trends in the epidemic process for mycoplasmal and chlamydial infections among children with respiratory diseases over several seasons from November 2018 to July 2020 based on the results of testing 617 serum samples. The data obtained indicate that, along with seasonal fluctuations in seropositivity, there is an epidemiological season from December 2019 to January 2020, characterized by a peak increase in the number of seropositive cases, the largest number of which was detected among school-age children hospitalized for community-acquired pneumonia.

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Acute respiratory infection: separating the wheat from the chaff

Medical Council ◽

10.21518/2079-701x-2019-11-166-170 ◽

2019 ◽

pp. 166-170

Author(s):

Article Editorial

Keyword(s):

Antibiotic Therapy ◽

Respiratory Infection ◽

Acute Respiratory Infection ◽

Respiratory Diseases ◽

Recurrent Infections ◽

Acute Respiratory Diseases ◽

Principles Of Treatment ◽

International Participation ◽

The Impact

In the framework of the XXI Congress of Pediatricians of Russia with international participation «Actual problems of pediatrics», held in early 2019, an interdisciplinary symposium on modern principles of treatment of children with acute respiratory diseases took place. In their reports, foreign and Russian experts highlighted the most discussed topics of pediatrics: the choice and application of immunostimulating therapy in the management of children with recurrent infections, the tactics of cough treatment in children, the impact of antibiotic therapy on microbiome and rational approaches to antibiotic therapy in childhood.

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TT Virus in the Nasal Secretions of Children with Acute Respiratory Diseases: Relations to Viremia and Disease Severity

Journal of Virology ◽

10.1128/jvi.77.4.2418-2425.2003 ◽

2003 ◽

Vol 77 (4) ◽

pp. 2418-2425 ◽

Cited By ~ 120

Author(s):

Fabrizio Maggi ◽

Massimo Pifferi ◽

Claudia Fornai ◽

Elisabetta Andreoli ◽

Elena Tempestini ◽

...

Keyword(s):

Respiratory Diseases ◽

Pathogenic Potential ◽

Genetic Characteristics ◽

Tt Virus ◽

Group 4 ◽

Acute Respiratory Diseases ◽

Nasal Secretions ◽

Intensive Investigation ◽

Blood Specimens ◽

A Site

ABSTRACT The natural history and pathogenic potential of the recently identified TT virus (TTV) are currently a matter of intensive investigation. In an attempt to shed some light on these issues, nasal and blood specimens of 1- to 24-month-old children hospitalized with a clinical diagnosis of acute respiratory disease (ARD) were examined for the presence, load, and genetic characteristics of TTV. The results have indicated that at least in young children, the respiratory tract not only represents a route by which abundant TTV can be shed into the environment but also may be a site of primary infection and continual replication. Although we found no compelling evidence that TTV was the direct cause of ARD in some of the children studied, the average loads of TTV were considerably higher in patients with bronchopneumonia (BP) than in those with milder ARD, raising interesting questions about the pathophysiological significance of TTV at this site. Furthermore, group 4 TTV was detected almost exclusively in children with BP.

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Evaluation of clinical efficacy of Derinat® in form of spray in practice of district therapist

Medical alphabet ◽

10.33667/2078-5631-2019-1-9(384)-38-46 ◽

2019 ◽

Vol 1 (9) ◽

pp. 38-46

Author(s):

A. P. Babkin ◽

A. A. Zuikova ◽

O. N. Krasnorutskaya ◽

Yu. A. Kotova ◽

D. Yu. Bugrimov ◽

...

Keyword(s):

Clinical Efficacy ◽

Respiratory Diseases ◽

Viral Infections ◽

Pharmacological Action ◽

The Body ◽

Natural Resistance ◽

Acute Respiratory Diseases ◽

T Helpers ◽

T Killers ◽

Stimulation Of

The widespread worldwide spread of acute respiratory diseases is an urgent problem in health care. Expressed polyetiology of respiratory diseases does not allow to limit the use of specific vaccine preparations and dictates the need to use to combat them a variety of non-specific means that stimulate the natural resistance of the human body. The main pharmacological action of sodium deoxyribonucleate is the stimulation of phagocytic activity of T-helpers and T-killers, increasing the functional activity of neutrophils and monocytes/ macrophages, providing regeneration and repair processes in the epithelial component of antiviral protection of the body. Based on the above, the study of the clinical efficacy of Derinat® in the form of spray in the treatment of acute respiratory viral infections is relevant.

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