PRE-BONNEVILLE LAKES IN CACHE VALLEY AND EXCAVATION OF CUTLER NARROWS ACROSS THE CACHE BUTTE DIVIDE IN THE WEST, NORTH-CENTRAL UTAH AND SOUTHEASTERN IDAHO

2020 ◽  
Author(s):  
Robert Q. Oaks ◽  
◽  
Susanne U. Janecke ◽  
Tammy M. Rittenour ◽  
Thad L. Erickson ◽  
...  
Circulation ◽  
2018 ◽  
Vol 137 (suppl_1) ◽  
Author(s):  
Inmaculada Hernandez ◽  
Samir Saba ◽  
Yuting Zhang

Background: Recent studies have shown strong geographic variation in oral anticoagulation (OAC) use in atrial fibrillation (AF); however, it remains unknown how this contributes to the geographic variation in ischemic stroke observed across the US. The objective of the present study was to evaluate the relationship between the geographic variation in the initiation of OAC and the incidence of ischemic stroke in a cohort of Medicare beneficiaries newly diagnosed with AF. Methods: Using 2013-2014 claims data from a 5% random sample of Medicare beneficiaries, we identified patients newly diagnosed with AF in 2013-2014 and categorized them according to their initiation of OAC. Our sample included 21,226 OAC initiators and 20,068 patients who did not initiate OAC therapy. We assigned each patient to one of the 9 US Census Divisions using the zip code, and collected their medical claims with a diagnosis of ischemic stroke. We constructed logistic regression models to estimate the average adjusted probability of OAC initiation and Poisson models to estimate the average adjusted rate of ischemic stroke, in each Census Division. Both estimates were adjusted for demographics, eligibility for Medicaid coverage and for low-income subsidy, enrollment in a Medicare Advantage Part D plan, and a comprehensive list of clinical characteristics. We computed the correlation between the average adjusted probability of OAC initiation and the average adjusted rate of ischemic stroke at the Census Division level. Results: The probability of OAC initiation was lowest in the West South Central (0.47) and highest in the West North Central (0.54) and New England (0.54). The average adjusted rate of ischemic stroke was lowest in the West North Central (0.09) and highest in the South Atlantic (0.14) and South West Central (0.14). The average adjusted probability of OAC initiation at the Census Division level and the average adjusted rate of ischemic stroke were inversely correlated, with R=-0.576, p-value=0.10. This suggests that variation in OAC initiation likely explains at least a third of geographic variation in ischemic stroke [R 2 =(-0.576) 2 =0.332]. Conclusions: Our results suggest that geographic variations in OAC initiation within the U.S. explain, in part, variations in the incidence of ischemic stroke among AF patients. Further mechanistic research using advanced causal mediation models is warranted.


PEDIATRICS ◽  
1948 ◽  
Vol 2 (1) ◽  
pp. 138-140

THE accompanying table summarizes the incidence of nine important communicable diseases, based on weekly telegraphic reports from State health departments. The reports from each State for each week are published in PUBLIC HEALTH REPORTS under the section "Incidence of Disease." [See Table in Source Pdf]. Diseases Above Median Incidence Measles—The number of cases of measles rose from 102,680 during the preceding 4 weeks to 114,983 during the 4 weeks ended May 22. The incidence was 3.4 times the number of cases reported for the corresponding period in 1947, which was, however, a comparatively low measles year, but it was only about 10 percent above the 1943-47 median. In the New England and East South Central sections the incidence was below the normal expectancy and in the South Atlantic section the number of cases was only slightly higher than the median for the preceding 5 years, but in the other 6 sections the increases over the median expectancy ranged from 1.1 times the median in the West North Central section to 3.4 times the median in the West South Central section. Poliomyelitis.— The number of cases of poliomyelitis rose from 126 during the preceding 4-week period to 440 during the current 4 weeks. The incidence was 3.5 times that reported for these weeks in 1947, which number (126 cases) also represents the 1943-47 median. An increase of this disease is expected at this season of the year, but the current number of cases represents a larger increase at this time than has normally occurred in preceding years. While each section of the country except New England contributed to the relatively high incidence, the greatest excesses over the 5-year medians were reported from the West North Central and West South Central sections. Of the total cases Texas reported 179, California 62, South Carolina 46, New Jersey 16, Iowa 14, Florida 12, Alabama 11, and Illinois, South Dakota, and Louisiana 10 each; 85 percent of the reported cases occurred in those 10 states which represent every section of the country except the New England and Mountain sections. Since the beginning of the year there have been 947 cases of poliomyelitis reported as compared with 894 and 810 for the corresponding period in 1947 and 1946, respectively.


2019 ◽  
Vol 64 (2) ◽  
Author(s):  
Mariana Castanheira ◽  
Timothy B. Doyle ◽  
Valerie Kantro ◽  
Rodrigo E. Mendes ◽  
Dee Shortridge

The activities of meropenem-vaborbactam and comparators against 152 (1.1%) carbapenem-resistant Enterobacterales (CRE) isolates identified among 13,929 Enterobacterales isolates collected from U.S. hospitals during 2016 to 2018 were evaluated. CRE rates were higher in the Middle Atlantic census division (3.5%) than in the other divisions (range, 0.0% for the West North Central division to 1.4% for the West South Central division).


2018 ◽  
Vol 5 (suppl_1) ◽  
pp. S360-S360 ◽  
Author(s):  
Thomas P Lodise ◽  
Roger Echols ◽  
Weiying Wang ◽  
Frank Corvino ◽  
Bin Cai

Abstract Background Carbapenem resistance (CR) is a growing threat in hospitals in the United States and worldwide. We evaluated the prevalence and geographic distribution of CR among six most common Gram-negative (GN) bloodstream infection (BSI) pathogens in US hospitals. Methods We analyzed microbiology data in a cohort of adults (≥18 years) hospitalized in 181 US hospitals contributing microbiology data to the Premier Healthcare Database (October 2010–September 2015) with blood cultures positive for six most common GN pathogens (S. maltophilia assumed 100% CR). We report CR prevalence by pathogen, hospital ward (ICU vs. floor), and census region. Results Of the 43,095 GN BSIs included, 1,513 (3.5%) were caused by the six most common CR pathogens (Figure 1). CR was more frequently isolated from patients with an ICU stay (4.7%) vs. those without (2.7%). Nearly 75% (n = 1,100) of CR occurred in nonfermenters (S. maltophilia, P. aeruginosa, and A. baumannii). Among individual organisms, the prevalence of CR—outside of S. maltophilia—was highest among A. baumannii, 35.1%, and lowest among E. coli, 0.2% (Figure 2). Geographically, CR prevalence ranged from highest in the Mountain region (7.1%) to lowest in the West North Central (2.3%) (Figure 3). The maximum CR prevalence occurred in A. baumannii from the East North Central (55.7%), and the minimum in E. coli from the West North Central (0.05%) regions. Conclusion Among six most frequently isolated pathogens in BSI, the overall CR prevalence is 3.5%. The wide variations in prevalence based on organism, location in the hospital, and geography emphasize the clinical importance of knowing local pathogen and resistance patterns in order to optimize empiric treatment. Disclosures A. F. Shorr, Astellas: Consultant and Speaker’s Bureau, Consulting fee, Research support and Speaker honorarium. Cidara: Consultant, Consulting fee. Merck & Co.: Consultant and Speaker’s Bureau, Consulting fee, Research support and Speaker honorarium. T. P. Lodise Jr., Motif BioSciences: Board Member, Consulting fee.


Circular ◽  
1952 ◽  
Author(s):  
E.W. Lohr ◽  
P.C. Benedict ◽  
H.A. Swenson ◽  
T.B. Dover

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