Drug utilisation among Dutch adolescents: a pharmacy prescription records study

2018 ◽  
Vol 104 (8) ◽  
pp. 745-748 ◽  
Author(s):  
Richelle C Kosse ◽  
Ellen S Koster ◽  
Tjalling W de Vries ◽  
Marcel L Bouvy
Keyword(s):  
Drug Use ◽  
Retrospective Cohort ◽  
Drug Utilisation ◽  
Healthcare Use ◽  
Adolescent Drug Use ◽  
Medication Prescription ◽  
Dutch Trial ◽  
Trial Register ◽  
Registration Number ◽  
Study Population

BackgroundStudies on adolescent drug use are scarce as most studies do not distinguish between children and adolescents. Therefore, we assessed overall drug use in adolescents.MethodsA retrospective cohort study was conducted using pharmacy dispensing records from 62 community pharmacies in the Netherlands. Dispensing records of the previous 5 years were extracted for adolescents (12–18 years).ResultsThe study population consisted of 47 421 adolescents who collected at least one medication prescription during adolescence (mean age 15.5±1.8 years; 48.9% males). Half of them collected dermatologicals (46.2% males; 52.3% females), followed by drugs for the respiratory system (43.4% males; 40.3% females) and anti-infectives for systemic use (31.3% males; 39.1% females). The percentage of males using dermatologicals slightly increased, while the percentage of female users decreased with age. The most prescribed active ingredient was methylphenidate.ConclusionsThese insights into adolescent drug use help us to better understand adolescent healthcare use.Trial registration numberDutch trial register NTR5061.

scholarly journals Use of Serotonergic Drugs in Canada for Gastrointestinal Motility Disorders: Results of a Retrospective Cohort Study

Scientifica ◽  
2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Biniam Kidane ◽  
Farouq Manji ◽  
Jennifer Lam ◽  
Brian M. Taylor
Keyword(s):  
Cohort Study ◽  
Drug Use ◽  
Surgical Management ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Tertiary Hospital ◽  
Study Population ◽  
Considerable Morbidity ◽  
Serotonergic Drugs ◽  
Effective Use

Background.Surgery for GI dysmotility is limited to those with severe refractory disease. Though effective, use of serotonergic promotility drugs has been restricted in Canada due to adverse events. We aimed to investigate utilization of promotility serotonergic drugs in patients under consideration for surgical management.Methods.A retrospective cohort study was conducted using prospectively collected data. The study population included consecutive patients referred to a motility clinic for consideration of bowel resection at a Canadian tertiary hospital (1996–2011). Univariable tests and multivariable logistic regression analyses were used to assess predictors of serotonergic drug use.Results.Of 128 patients, the majority (n=98, 76.6%) had constipation-dominant symptoms. Only 25% (n=32) had tried serotonergic promotility drugs. There was no association between use of these drugs and severity of constipation nor was there an association between serotonergic drug use and presence of diffuse dysmotility (allp>0.05). The majority of patients (n=97, 75.8%) underwent some type of surgical resection, which was associated with considerable morbidity (n=13, 13.4%).Conclusions.Surgical management of GI dysmotility results in serious morbidity. Serotonergic promotility drugs may allow patients to avoid surgery but disease severity does not predict use of these drugs.

Perceptions of Harmfulness, Drug Prevention Education, and Adolescent Drug Use

2007 ◽  
Author(s):  
Lydia Odenat ◽  
Joel Meyers ◽  
Jeffrey S. Ashby ◽  
Courtney B. Chambless ◽  
Megan Marshall ◽  
...  
Keyword(s):  
Drug Use ◽  
Drug Prevention ◽  
Prevention Education ◽  
Adolescent Drug Use

scholarly journals Can a Difference in Gestational Age According to Biparietal Diameter and Abdominal Circumference Predict Intrapartum Placental Abruption?

2021 ◽  
Vol 10 (11) ◽  
pp. 2413
Author(s):  
Jee-Youn Hong ◽  
Jin-Ha Kim ◽  
Seo-yeon Kim ◽  
Ji-Hee Sung ◽  
Suk-Joo Choi ◽  
...  
Keyword(s):  
Gestational Age ◽  
Odds Ratio ◽  
Retrospective Cohort ◽  
Maternal Age ◽  
Placental Abruption ◽  
Independent Predictor ◽  
Abdominal Circumference ◽  
Biparietal Diameter ◽  
Study Population ◽  
Independent Risk Factors

This study aimed to investigate whether a difference in gestational age according to biparietal diameter (BPD) and abdominal circumference (AC) could be a clinically useful predictor of placental abruption during the intrapartum period. This retrospective cohort study was based on singletons who were delivered after 32 + 0 weeks between July 2015 and July 2020. We only included cases with at least two antepartum sonographies available within 4 weeks of delivery (n = 2790). We divided the study population into two groups according to the presence or absence of placental abruption and compared the clinical variables. The incidence of placental abruption was 2.0% (56/2790) and was associated with an older maternal age, a higher rate of preeclampsia, and being small for the gestational age. A difference of >2 weeks in gestational age according to BPD and AC occurred at a higher rate in the placental abruption group compared to the no abruption group (>2 weeks, 21.4% (12/56) vs. 7.5% (205/2734), p < 0.001; >3 weeks, 12.5% (7/56) vs. 2.0% (56/2734), p < 0.001). Logistic regression analysis revealed that the differences of >2 weeks and >3 weeks were both independent risk factors for placental abruption (odds ratio (OR) (95% confidence interval), 2.289 (1.140–4.600) and 3.918 (1.517–9.771), respectively) after adjusting for maternal age, preeclampsia, and small for gestational age births. We identified that a difference in gestational age of >2 weeks between BPD and AC could be an independent predictor of placental abruption.

Personality, Motivation, and Adolescent Drug Use Patterns

1976 ◽  
Vol 5 (2) ◽  
pp. 17-23
Author(s):  
Samuel E. Krug ◽  
Thomas J. Henry
Keyword(s):  
Drug Use ◽  
Adolescent Drug Use ◽  
Use Patterns ◽  
Drug Use Patterns

scholarly journals Healthcare cost associations of patients who use illicit drugs in Florida: a retrospective analysis

2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Jessica L. Ryan ◽  
Veronica R. Rosa
Keyword(s):  
Drug Use ◽  
Patient Care ◽  
Healthcare Cost ◽  
Healthcare Costs ◽  
Illicit Drugs ◽  
Illicit Drug ◽  
Multiple Drug ◽  
Study Population ◽  
Multiple Drugs ◽  
Hospital Research

Abstract Background Illicit drug use increases visits to the hospital. Research is limited on the costs of these healthcare visits by illicit drug. Methods Florida’s Agency for Health Care Administration’s emergency department and inpatient datasets from 2016 to 2018 were analyzed. Adults who used an illicit drug were included in the study population resulting in 709,658 observations. Cost-to-charge ratios were used to estimate healthcare costs. Linear regression analyzed associations of illicit drugs with total healthcare cost. Results Total healthcare costs are estimated at $6.4 billion over the 3 year period. Medicare paid for the most patient care ($2.16 billion) with Medicaid and commercial insurance each estimated at $1.36 billion. Cocaine (9.25%) and multiple drug use (6.12%) increased the costs of an ED visit compared to a patient with cannabis SUD. Opioids (23.40%) and inhalants use (16.30%) increased the costs of inpatient compared to cannabis SUD. Conclusion Healthcare costs are high of patients with illicit drug SUD and poisoning, over half of which are paid for with tax payer dollars and to an unknown degree hospital write-offs. Injuries and illness of patients using cocaine and multiple drugs are associated with more expensive ED patient care and opioids and inhalants are associated with more expensive inpatient care.

scholarly journals Healthcare use prior to suicide in the Stockholm County population 2011-2016

2019 ◽  
Vol 29 (Supplement_4) ◽  
Author(s):  
J Narusyte ◽  
K Kosidou ◽  
C Dalman
Keyword(s):  
Age Groups ◽  
Public Health Problem ◽  
Major Public Health Problem ◽  
Healthcare Use ◽  
Stockholm County ◽  
Suicide Death ◽  
Death Registry ◽  
County Population ◽  
Study Population ◽  
One Year

Abstract Background Suicide is a major public health problem. A detailed description of healthcare use prior to suicide can serve to improve prevention strategies. The aim of the study was to describe the patterns of primary, specialized outpatient, and inpatient healthcare use from two weeks and up to one year prior to suicide in Stockholm County. Methods The study population included all 15 year or older suicide victims who died in Stockholm County 2011-2016 (n = 1950) identified through National Cause of Death Registry. Data on number of visits and contacts with healthcare among suicide victims were obtained from VAL healthcare use registry in Stockholm County. Healthcare use was depicted from one year to up to two weeks prior to suicide death. Results Preliminary results showed that there were 65% and 57% of women and men, respectively, who had at least one contact with healthcare during the last two weeks before suicide death. Measured one year prior to suicide, there were 93% of women and 85% of men who had at least one contact with healthcare. Among those who had at least one contact with healthcare two weeks prior to suicide, there were 16% of women and 12% of men who were hospitalized, 55% of women and 47% of men who had a contact with specialized outpatient care, and 32% of women and 27% of men who had a contact with primary healthcare. The proportion of those who did not have any contact with healthcare during the six months prior to suicide decreased gradually with increasing age among men (23% at ages of 15-24 years old and 7% at ages of 65 and older). There were on average 7% of women in all age groups who did not have any contact with healthcare during the six months prior to suicide. Conclusions The majority of the suicide victims had a contact with healthcare during the last year prior to suicide death. The findings suggest that suicide prevention efforts may target improved tools for clinically-based risk assessment. Key messages The majority of the suicide victims had at least one contact with healthcare during the last year prior to suicide death. Those who did not have any contact with healthcare during six months prior to suicide were more likely to be young men.

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