Parent-reported health status of preterm survivors in a Canadian cohort

2021 ◽  
pp. fetalneonatal-2021-321635
Author(s):  
Satvinder Ghotra ◽  
David Feeny ◽  
Ronald Barr ◽  
Junmin Yang ◽  
Saroj Saigal ◽  
...  
Keyword(s):  
Health Status ◽  
Age Groups ◽  
Severity Of Illness ◽  
Preschool Age ◽  
Health Concern ◽  
Health Concerns ◽  
Related Quality ◽  
National Cohort ◽  
Reported Health ◽  
Prospective Longitudinal

ObjectivesHealth status (HS)/ health-related quality of life measures, completed by self or proxy, are important outcome indicators. Most HS literature on children born preterm includes adolescents and adults with limited data at preschool age. This study aimed to describe parent-reported HS in a large national cohort of extreme preterm children at preschool age and to identify clinical and sociodemographic variables associated with HS.MethodsInfants born before 29 weeks’ gestation between 2009 and 2011 were enrolled in a prospective longitudinal national cohort study through the Canadian Neonatal Network (CNN) and the Canadian Neonatal Follow-Up Network (CNFUN). HS, at 36 months’ corrected age (CA), was measured with the Health Status Classification System for Pre-School Children tool completed by parents. Information about HS predictors was extracted from the CNN and CNFUN databases.ResultsOf 811 children included, there were 79, 309 and 423 participants in 23–24, 25–26 and 27–28 weeks’ gestational age groups, respectively. At 36 months’ CA, 78% had a parent-reported health concern, mild in >50% and severe in 7%. Most affected HS attributes were speech (52.1%) and self-care (41.4%). Independent predictors of HS included substance use during pregnancy, infant male sex, Score for Neonatal Acute Physiology-II, bronchopulmonary dysplasia, severe retinopathy of prematurity, caregiver employment and single caregiver.ConclusionMost parents expressed no or mild health concerns for their children at 36 months’ CA. Factors associated with health concerns included initial severity of illness, complications of prematurity and social factors.

scholarly journals Effect of Inotropes on Patient-Reported Health Status in End-Stage Heart Failure

2021 ◽  
Vol 14 (2) ◽  
Author(s):  
John-Ross D. Clarke ◽  
Ralph Riello ◽  
Larry A. Allen ◽  
Mitchell A. Psotka ◽  
John R. Teerlink ◽  
...  
Keyword(s):  
Health Status ◽  
Health Related Quality ◽  
Reduced Ejection Fraction ◽  
Randomized Controlled ◽  
Patient Reported ◽  
Related Quality ◽  
Health Related ◽  
Reported Health ◽  
End Stage

Background: A growing population of patients with end-stage heart failure (HF) with reduced ejection fraction has limited treatment options to improve their quality and quantity of life. Although positive inotropes have failed to show survival benefit, these agents may enhance patient-reported health status, that is, symptoms, functional status, and health-related quality of life. We sought to review the available clinical trial data on positive inotrope use in patients with end-stage HF and to summarize evidence supporting the use of these agents to improve health status of patients with end-stage HF. Methods: A literature review of randomized controlled trials examining the use of positive inotropy in HF with reduced ejection fraction was conducted. We searched MEDLINE, SCOPUS, and Web of Science between January 1980 to December 2018 for randomized controlled trials that used as their main outcome measures the effects of inotrope therapy on (1) morbidity/mortality, (2) symptoms, (3) functional status, or (4) health-related quality of life. Inotropes of interest included adrenergic agents, phosphodiesterase inhibitors, calcium sensitizers, myosin activators, and SERCA2a (sarcoplasmic reticulum Ca 2+ -ATPase) modulators. Results: Twenty-two out of 26 inotrope randomized controlled trials measured the effect of inotropes on at least one patient-reported health status domain. Among the 22 studies with patient-related health status outcomes, 11 (50%) gauged symptom response, 15 (68%) reported functional capacity changes, and 12 (54%) reported health-related quality of life measures. Fourteen (64%) of these trials noted positive outcomes in at least one health status domain measured; 11 (79%) of these positive studies used agents that worked through phosphodiesterase inhibition. Conclusions: There has been a lack of standardization surrounding measurement of patient-centered outcomes in studies of inotropes for end-stage HF with reduced ejection fraction. The degree to which positive inotropes can improve patient-reported health status and the adverse risk they pose remains unknown.

scholarly journals Living with Migraine in Canada – A National Community-Based Study

2019 ◽  
Vol 46 (2) ◽  
pp. 216-223
Author(s):  
Kristianne Chelsea Altura ◽  
Scott B. Patten ◽  
Jeanne V. A. Williams ◽  
Kirsten M. Fiest ◽  
Nathalie Jetté
Keyword(s):  
Health Status ◽  
Age Groups ◽  
Health Utility Index ◽  
Health Utility ◽  
Community Based ◽  
Cross Sectional ◽  
Utility Index ◽  
Related Quality ◽  
Health Related ◽  
The Impact

ABSTRACT:Objective: To develop a detailed profile of individuals living with migraine in Canada. Such a profile is important for planning and administration of services. Methods: The 2011–2012 Survey of Living with Neurological Conditions in Canada (SLNCC), a cross-sectional community-based survey, was used to examine a representative sample of migraineurs (N = 949) aged 15 years and older. Several health-related variables were examined (e.g., general health, health utility index (HUI) [a measure of health status and health-related quality of life, where dead = 0.00 and perfect health = 1.00], stigma, depression, and social support). Respondents were further stratified by sex, age, and age of migraine onset. Weighted overall and stratified prevalence estimates and odds ratios, both with 95% CIs, were used to estimate associations. Results: Overall, males had poorer health status compared with females (e.g., mean HUI was 0.67 in males vs. 0.82 in females; men had over two times the odds of their migraine limiting educational and job opportunities compared with females). Poorer health-related variables were seen in the older age groups (35–64 years/≥65 years) compared with the 15–34-year age group. There were no differences between those whose migraine symptoms began before versus after the age of 20 years. Conclusions: In this Canadian sample, migraine was associated with worse health-related variables in men compared with women. However, both men and women were significantly affected by migraine across various health-related variables. Thus, it is important to improve clinical and public health interventions addressing the impact of migraine across individuals of all ages, sexes, and sociodemographic backgrounds.

scholarly journals Population-based Data at Ages 31 and 46 Show Decreased HRQoL and Life Satisfaction in Women with PCOS Symptoms

2020 ◽  
Vol 105 (6) ◽  
pp. 1814-1826 ◽  
Author(s):  
Salla Karjula ◽  
Laure Morin-Papunen ◽  
Stephen Franks ◽  
Juha Auvinen ◽  
Marjo-Riitta Järvelin ◽  
...  
Keyword(s):  
Life Satisfaction ◽  
Health Status ◽  
Polycystic Ovary ◽  
Population Based ◽  
Longitudinal Assessment ◽  
Related Quality ◽  
Health Related ◽  
Reported Health ◽  
Self Reported Health Status ◽  
The Impact

Abstract Context Polycystic ovary syndrome (PCOS) is associated with decreased health-related quality of life (HRQoL), but longitudinal data beyond the reproductive years are lacking, and the impact of isolated PCOS symptoms is unclear. Objective To study generic HRQoL using the 15D questionnaire, life satisfaction, and self-reported health status in women with PCOS symptoms at ages 31 and 46 years. Design A longitudinal assessment using the Northern Finland Birth Cohort 1966. Setting General community. Participants The 15D data were available for women reporting isolated oligo-amenorrhea (OA; at age 31 years, 214; and 46 years, 211), isolated hirsutism (H; 31 years, 211; and 46 years, 216), OA + H (PCOS; 31 years, 74; and 46 years, 75), or no PCOS symptoms (controls; 31 years, 1382; and 46 years, 1412). Data for life satisfaction and current health status were available for OA (31 years, 329; and 46 years, 247), H (31 years, 323; and 46 years, 238), PCOS (31 years, 125; and 46 years, 86), control (31 years, 2182; and 46 years, 1613) groups. Intervention(s) None. Main Outcome Measure(s) 15D HRQoL, questionnaires on life satisfaction, and self-reported health status. Results HRQoL was lower at ages 31 and 46 in women with PCOS or H than in the controls. PCOS was an independent risk factor for low HRQoL, and the decrease in HRQoL in PCOS was similar to that of women with other chronic conditions, such as asthma, migraine, rheumatoid arthritis, and depression. The risk for low HRQoL in PCOS remained significant after adjusting for body mass index, hyperandrogenism, and socioeconomic status. Mental distress was the strongest contributing factor to HRQoL. PCOS was also associated with a risk for low life satisfaction and a 4-fold risk for reporting a poor health status. Conclusions Women with PCOS present with low HRQoL, decreased life satisfaction, and a poorer self-reported health status up to their late reproductive years. Assessments and interventions aiming to improve HRQoL in PCOS should be targeted beyond the fertile age.

EUROQoL-5D as a valid patient-reported outcome measurement (PROM) tool to predict health-related quality of life (HRQoL) and survival in patients with hematological malignancies.

2020 ◽  
Vol 38 (15_suppl) ◽  
pp. e19141-e19141
Author(s):  
Raul Cordoba ◽  
Adriana Pascual ◽  
Javier Martinez-Peromingo ◽  
Ana-Isabel Hormigo ◽  
Elham Askari ◽  
...  
Keyword(s):  
Health Status ◽  
Outcome Measurement ◽  
Patient Reported Outcome ◽  
Patient Reported ◽  
Related Quality ◽  
Health Related ◽  
Euroqol 5D ◽  
Reported Health ◽  
Self Reported Health Status

e19141 Background: Patient-Reported Outcome Measurement (PROM) is the way to collect not only Health-Related Quality of Life (HRQoL) but also symptoms. EUROQOL-5D is a PROM tool explored widely in patients with cancer, although is not specific for cancer patients. The primary end-point of this project is to analyse the significance of impairments in EUROQOL-5D domains in overall survival of patients with hematological malignances, and the utility to incorporate as a PROM tool in a daily clinical practice. Methods: Patients with hematologic malignancies attended at Fundacion Jimenez Diaz University Hospital were assessed with EUROQOL-5D prior to receive any therapy. Self-reported health status stated as better, equal or worse was recorded at the time of assessment. Other variables such as age, sex, diagnosis and ECOG was collected to analyze their impact in survival. Results: From January 1, 2017 to December 31, 2019, 390 consecutive patients were included. Median age was 72 years (range 18-92), 194 (49.7%) were female, with a diagnosis of lymphoma in 257 (65.9%) and myeloma in 70 (17.9%), and ECOG 0-1 in 78.2% of patients. With a median follow-up of 10.5 months (range 0-32 months), we registered 72 events for overall survival. In the univariate analysis, age > 76 years (AUC 0.739, Likelyhood Ratio 3.321, p < 0.0001), ECOG 2-4 (OR 11.161, 95% CI 5.276-23.610, p < 0.0001), impairment in EUROQOL-5D domains such us mobility (OR 2.896, 95%CI 1.406-5.967, p = 0.003), self-care (OR 3.959, 95%CI 1.732-9.050, p = 0.001) and usual activities (OR 3.190, 95%CI 1.573-6.467, p = 0.001), but not pain/disconfort nor anxiety/depression were identified as prognostic factors for shorter survival. Self-reported health status (OR 3.975, 95%CI 1.845-8.565, p < 0.0001) was also a prognostic factor for survival. Impairments in EUROQOL-5D were also prognostic in patients with ECOG 0-1 (p < 0.001). In the multivariate analysis, only ECOG 2-4 and self-reported health status remained with statistical significance. Conclusions: EUROQOL-5D is a valid tool to be incorporated as a PROM tool in pacients with hematological malignancies. Impairments in mobility, self-care and usual activities will identify a poorer prognosis group that would need closer monitoring.

scholarly journals Determination of the Impact Between Varying Lifestyle Factors and Health Status Concerns Among College-Age Students (P04-100-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Lisa Dalrymple ◽  
Prudence Pollard
Keyword(s):  
Physical Activity ◽  
Health Status ◽  
Health Behavior ◽  
Intervention Program ◽  
Health Concern ◽  
Health Concerns ◽  
College Age ◽  
Funding Sources ◽  
Lifestyle Choices ◽  
The Impact

Abstract Objectives The significance and objective of this study is to (1) investigate the influence current health concerns have on lifestyle choices using self-reporting assessment surveys, and (2) determine the correlation and/or impact between the stated variables on overall health status of college-age students. Methods A Health Behavior Study was conducted by the office of Healthy Campus 2020(R)(HC2020(R)), a campus-wide comprehensive wellness intervention program. IRB approved surveys were disseminated to students, (N = 59), to investigate student's health status, health behavior, possible changes in health status after one-year exposure to HC2020(R) principles, and relationships between health variables and behavior. Coded responses were obtained and analyzed. Results Descriptive analysis and correlation coefficient are used to analyze data responses. Among 14 significant ongoing health concerns listed as options, diabetes ranked highest as a health concern at 34%. Heart disease & stroke (29%), asthma and/or lung disease (24%), and both cancer and obesity at 20% followed, respectively. Consequently, 64% of students indicated they engaged in exercise or physical activity daily, emphasizing their awareness of the importance of physical activity and living a healthy lifestyle. Conclusions Results indicate health concerns among college-age students conducting self-reporting assessment surveys may influence positive lifestyle choices. Seventy-eight % (%) of students who participated in the study, ages 17–20, reported at least 4 of the same concerns of the CDC's top 10 public health problems and leading cause of death in the US. Funding Sources Funding sources for the research conducted through the office of HC2020(R) at Oakwood University was provided by The Department of Education, Title III.

Age, Anxiety, and Self-Reported Health

1976 ◽  
Vol 7 (1) ◽  
pp. 49-58 ◽  
Author(s):  
Robert R. Mc Crae ◽  
Paul T. Bartone ◽  
Paul T. Costa
Keyword(s):  
Middle Age ◽  
Age Groups ◽  
Health Problems ◽  
Self Report ◽  
Health Concern ◽  
Physical Health Status ◽  
Reported Health ◽  
Normal Males ◽  
Anxious Group ◽  
Report Measure

A sample of 472 normal males ranging in age from twenty-five to eighty-two was divided into anxious and adjusted groups on the basis of a cluster analysis of the Cattell 16PF test, and compared for scores on a self-report measure of health. While the anxious men reported more symptoms than the adjusted in the young and middle age groups, there was no difference in the old group. Although anxiety was found to be unrelated to health as evaluated by physicians' examinations, the anxious men indeed reported more health problems in eight major areas of health concern than was warranted by their actual physical health status. This relation also did not hold in the old group. Anxious men seemed to be more vigilant about their health in young and middle age groups, but not in the old group. This was interpreted as a defensive denial of symptoms in the old anxious group; for a person with trait anxiety, anxiety about approaching death and increasing health problems is just too much to bear, and he resorts to denying symptoms in an effort to diminish his anxiety.

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