scholarly journals Prevalence of neurological problems in a community-based sample of paediatric coeliac disease: a cross-sectional study

2021 ◽  
pp. archdischild-2021-321770
Author(s):  
Thom O'Neill ◽  
Peter M Gillett ◽  
Philippa Wood ◽  
David Beattie ◽  
Deepa J Patil ◽  
...  

BackgroundThe prevalence of and risk factors for neurological problems in childhood coeliac disease (CD) are unclear.MethodsWe performed a cross-sectional, community-based audit of CD in children diagnosed from January 2010 to December 2016 in Lothian.Results79 (28%) of 284 children with CD (201, 70.8% female) (mean age 8.3 years, range of 1–16) had neurological problems. Fifteen (5%) had headaches/migraine, 3 (1%) seizures, 32 (11%) ASD (autistic spectrum disorder), 5 (2%) ADD (attention deficit disorder) and 4 (1%) had ADHD (attention deficit hyperactivity disorder). Fifteen (5%) had anxiety (n=10, 3.5%) or low mood (n=5, 2%). Neurological problems were more common with later age at CD diagnosis (OR 1.07, 95% CI 1.01 to 1.14) and male gender (OR 1.69, 95% CI 0.96 to 2.95).ConclusionPrevalence of neurological problems in children with CD in Lothian is lower than published adult CD studies and similar or lower to the reported prevalence in the general childhood population.

2019 ◽  
pp. 85-91
Author(s):  
Dinh Duong Le ◽  
Van Thang Vo ◽  
Thi Mai Nguyen ◽  
Thi Han Vo ◽  
Huu Chau Duc Nguyen ◽  
...  

Objectives: The study aims to explore the prevalence of attention deficit hyperactivity disorder and to examine the associated factors with ADHD among primary students by Vanderbilt ADHD rating scale for teacher and parents. Methods: A cross-sectional study design was conducted in 564 students who selected randomly in 4 primary schools in Hue city. Vanderbilt ADHD rating scale for parents and teachers were applied to evaluate the ADHD of children over 6 months ago. Results: The overall prevalence of children who had high risk with ADHD was 4.1% (95%CI: 2.44 - 5.72), including 4.6% and 4.8% in the rating of teachers and parents, respectively. Male was more likely to have ADHD than female (OR adj: 4.64 (95%CI: 1.53 - 14.05) and lack of closely friend (OR adj: 5.11 (95% CI: 2.13 - 12.24). Conclusion: Vanderbilt ADHD diagnosis rating scale for teachers and parents can be used to early recognization children with a high risk of ADHD. Key words: ADHD, Vanderbilt, ratings scale, teacher, parent, children


2018 ◽  
Vol 11 (1) ◽  
pp. 58-69 ◽  
Author(s):  
Ana Carolina Sierra Montoya ◽  
Sandra Catalina Mesa Restrepo ◽  
Jorge Mauricio Cuartas Arias ◽  
William Cornejo Ochoa

Introduction: Attention Deficit Hyperactivity Disorder (ADHD) is the most common behavioral issue for children. One of the sleeping disorders most frequently related to ADHD is the Restless Legs Syndrome (RLS), characterized by an irresistible urge to move the legs, something that is generally associated with paresthesias and motor restlessness. The prevalence rate of RLS in children diagnosed with ADHD is close to 18%, but in Colombia, these cases have been hardly studied. Objective: To determine the frequency of RLS, in children with ADHD. Methods: A cross-sectional study, filled out by parents of children diagnosed with ADHD, were analyzed. This questionnaire contained clinical criteria for classifying ADHD according to the DSM-IV, as well as diagnostic criteria for RLS by the National Institutes of Health (2003). Results: A predominance rate of 65.6% in combined ADHD was observed in children with RLS criteria. Upon carrying out an exploratory data analysis, it was found that having a family history of RLS and belonging to the middle or low socioeconomic strata are conditions associated with the presence of RLS in children with ADHD, with a significant p (p < 0.000) and a PR of 4.47 (3.16-6.32). Conclusions: The prevalence of RLS was similar to the findings of other clinical investigations. However, it highlights new prevalence values in relation to the comorbidity between ADHD and RLS, suggesting the need for new clinical and therapeutic alternatives amidst the presence of both syndromes.


Cephalalgia ◽  
2018 ◽  
Vol 39 (6) ◽  
pp. 711-721 ◽  
Author(s):  
Claire Carpenet ◽  
Elie Guichard ◽  
Christophe Tzourio ◽  
Tobias Kurth

Objectives The aim was to evaluate the association of self-perceived levels of attention deficit and hyperactivity symptoms with non-migraine and migraine headaches among university students. We also evaluated their association with migraine aura. Methods Study subjects were all participants in the internet-based Students Health Research Enterprise. Scores were built to evaluate global attention and hyperactivity symptom levels, self-perceived attention deficit levels and self-perceived hyperactivity symptom levels based on the Adult Attention Deficit and Hyperactivity Disorder Self-Report Scale (ASRS v1.1.). We used standardised questions to classify headache and group participants into “no headache,” “non-migraine headache,” “migraine without aura” or “migraine with aura”. Results A total of 4816 students were included (mean age 20.3 ± 2.8 years; 75.5% women). Compared with participants without headache, we found significant associations between global ADHD scores and migraine. Students in the highest quintile of global ASRS scores had adjusted odds ratio (aOR) of 1.95 (95% CI 1.56–2.45) when compared to the lowest. This association was mainly driven by an association between self-perceived hyperactivity and migraine with aura. The aOR for migraine with aura was 2.83 (95% CI 2.23–3.61) for students in the highest quintile of hyperactivity. No significant association was found for any attention and hyperactivity symptom level measure and non-migraine headache and between self-perceived levels of attention deficit and migraine. Conclusions Among students in higher education in France, self-perceived levels of attention deficit and hyperactivity symptoms were selectively associated with migraine. The association was strongest for the hyperactivity domain and migraine with aura.


2017 ◽  
Vol 21 (9) ◽  
pp. 641-647 ◽  
Author(s):  
Ismael San Mauro Martín ◽  
Javier Andrés Blumenfeld Olivares ◽  
Elena Garicano Vilar ◽  
Manuela Echeverry López ◽  
Marta García Bernat ◽  
...  

2021 ◽  
Vol 12 ◽  
Author(s):  
Felippe Mendonca ◽  
Felipe Kenji Sudo ◽  
Gustavo Santiago-Bravo ◽  
Natalia Oliveira ◽  
Naima Assuncao ◽  
...  

Background: Attention-Deficit/Hyperactivity Disorder (ADHD) is a highly prevalent neurodevelopmental condition, which may be associated with life-enduring cognitive dysfunction. It has been hypothesized that age-related cognitive decline may overlap with preexisting deficits in older ADHD patients, leading to increased problems to manage everyday-life activities. This phenomenon may mimic neurodegenerative disorders, in particular Mild Cognitive Impairment (MCI). This cross-sectional study aims to assess cognitive and behavioral differences between older subjects with ADHD and MCI.Methods: A total of 107 older participants (41 controls; 40 MCI and 26 ADHD; mean age = 67.60 ± 7.50 years; mean schooling = 15.14 ± 2.77 years; 65.4% females) underwent clinical, cognitive, and behavioral assessments by a multidisciplinary team at the Memory Clinic, D'Or Institute for Research and Education, Rio de Janeiro, Brazil. Mean scores in neuropsychological tasks and behavioral scales were compared across groups.Results: Participants with ADHD showed poorer performances than controls in episodic memory and executive function with large effect-sizes. Performances were comparable between MCI and ADHD for all domains.Discussion: MCI and ADHD in older individuals are dissociated clinical entities with overlapping cognitive profiles. Clinicians ought to be aware of these converging phenotypes to avoid misdiagnosis.


2021 ◽  
Author(s):  
Haregewoin Mulat Sebhat ◽  
Niguse Muluneh ◽  
Tewodros Eyasu

Abstract BackgroundWhen attention deficit Hyperactivity Disorder (ADHD) presents in epileptic children, it makes the treatment complicated and the prognosis poor. Hence, understanding the magnitude of ADHD and associated factors would be important to have a policy intention towards these people and to design appropriate interventions. Therefore, the current study was conducted to determine co-morbidity of attention deficit hyperactivity disorder (ADHD) and associated factors in children with seizure disorders.Methods A hospital based cross-sectional study was conducted by taking 260children who had follow ups in the pediatric seizure clinic. The systematic random sampling technique was used to recruit participants. A structured, pretested and interviewer administered questionnaire which included questions on associated factors and standard disruptive behavioural disorder (DBD) rating scale was used to collect data. Data were coded, entered and cleaned by using the Epi-Data version 3.1 and exported to SPSS version 20 for further analysis. The multivariate binary logistic regression was used to cheek the association between independent and dependent variables. Variables with significant associations were identified on the basis of OR, with a 95%CI and p-value of < 0.05 and considered as statistically significant.ResultThe prevalence of ADHD among epileptic children was found to be 115(44.2%),with a confidence interval of (38.1-50.5),out of which only 3(2.6%) were detected as having mental health problems by the clinician. The predominant subtype was inattentive type 96(61.1%). Factors significantly associated with ADHD were male sex (AOR = 2.70 CI: 1.46-4.97), family history of seizure disorder (AOR=2.42CI:1.26-4.65), family history mental illnesses (AOR=4.14 CI: 1.76-9.68), sudden onset of seizure (AOR=2.37 CI: 1.32-4.27) and uncontrolled seizure (AOR=2.55 CI: 1.41-4.61). Conclusion Attention deficit hyperactivity disorder was common among children with seizure disorders in the study area. Therefore, interventions that would address such factors would help to overcome further complications.


BJPsych Open ◽  
2021 ◽  
Vol 7 (6) ◽  
Author(s):  
Indermeet Sawhney ◽  
Bhathika Perera ◽  
Paul Bassett ◽  
Asif Zia ◽  
Regi T Alexander ◽  
...  

Background Attention-deficit hyperactivity disorder (ADHD) is common among people with intellectual disability. Diagnosing ADHD in this clinically and cognitively complex and diverse group is difficult, given the overlapping psychiatric and behavioural presentations. Underdiagnoses and misdiagnoses leading to irrational polypharmacy and worse health and social outcomes are common. Diagnostic interviews exist, but are cumbersome and not in regular clinical use. Aims We aimed to develop a screening tool to help identify people with intellectual disability and ADHD. Method A prospective cross-sectional study, using STROBE guidance, invited all carers of people with intellectual disability aged 18–50 years open to the review of the psychiatric team in a single UK intellectual disability service (catchment population: 150 000). A ten-item questionnaire based on the DSM-V ADHD criteria was circulated. All respondents’ baseline clinical characteristics were recorded, and the DIVA-5-ID was administered blinded to the individual questionnaire result. Fisher exact and multiple logistic regressions were conducted to identify relevant questionnaire items and the combinations that afforded best sensitivity and specificity for predicting ADHD. Results Of 78 people invited, 39 responded (26 men, 13 women), of whom 30 had moderate-to-profound intellectual disability and 38 had associated comorbidities and on were medication, including 22 on psychotropics. Thirty-six screened positive for ADHD, and 24 were diagnosed (16 men, eight women). Analysis showed two positive responses on three specific questions to have 88% sensitivity and 87% specificity, and be the best predictor of ADHD. Conclusions The three-question screening is an important development for identifying ADHD in people with intellectual disability. It needs larger-scale replication to generate generalisable results.


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