Compliance and long-term effect of azathioprine in 65 rheumatoid arthritis cases.

Abstract Objective The study objective was to evaluate the long-term effect of radiosynoviorthesis (RSO) on the progression of radiological and nuclear-medical osteoarthritic features of hip and ankle joint in patients with osteoarthritis and rheumatoid arthritis. Patients and Methods The study included 89 hip joints of 81 patients, of which 48 had osteoarthritis (OA) and 33 had rheumatoid arthritis (RA). In terms of ankle joints, 64 patients were included of which 43 suffered from OA and 21 from RA. The mean follow-up time was 9.2 years for OA and 8.9 years for RA patients. Patients with RA were the active control group. Structural alterations of the hip joints were evaluated following Kellgren-Lawrence score and of ankle joint following Takakura score for both disease entities. For the evaluation of synovitis 2-phase bone scintigraphy was performed. Results RSO could prevent radiologic status deterioration among 70.6 % of hip osteoarthritic patients and 73.7 % among the hip RA patients. No structural progression was observed in 79.1 % of the treated ankle joints in patients with OA and in 85.7 % of the ankle joints in patients with RA.The scintigraphic response rate for the hip joints of OA patients was 68.6 %, 76.3 % for hip joints of RA patients, 83.1 %, ankle joints of OA patients, and 90.4 % ankle joints of RA patients.The radiographic and scintigraphic RSO response rates were not significantly higher for both joints in RA than OA patients. Conclusion RSO can be a good alternative in the treatment of synovitis and prevention of deterioration of inflammatory and radiographic features even in patients suffering from osteoarthritis and rheumatoid arthritis. RSO may have also a long-term effect to stop or delay progression of both diseases.

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An observation on the severity of periodontal disease in past cigarette smokers suffering from rheumatoid arthritis- evidence for a long-term effect of cigarette smoke exposure?

BMC Oral Health ◽

10.1186/s12903-018-0531-5 ◽

2018 ◽

Vol 18 (1) ◽

Cited By ~ 3

Author(s):

Márk Antal ◽

Emese Battancs ◽

Márta Bocskai ◽

Gábor Braunitzer ◽

László Kovács

Keyword(s):

Rheumatoid Arthritis ◽

Periodontal Disease ◽

Cigarette Smoke ◽

Smoke Exposure ◽

Term Effect ◽

Cigarette Smoke Exposure ◽

Cigarette Smokers ◽

Long Term Effect

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Long-Term Effect of Gold Therapy on Rheumatoid Arthritis. Comparison between Injectable and Oral Gold Therapy.

Orthopedics & Traumatology ◽

10.5035/nishiseisai.43.733 ◽

1994 ◽

Vol 43 (2) ◽

pp. 733-738

Author(s):

Hisakata Yamada ◽

Masakazu Kondo ◽

Tatsuoki Mashima ◽

Norio Shinohara ◽

Koichiro Yokoyama ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Term Effect ◽

Gold Therapy ◽

Long Term Effect

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Case Report on Steroid Induced Cushing Syndrome

Journal of Drug Delivery and Therapeutics ◽

10.22270/jddt.v9i4-s.3269 ◽

2019 ◽

Vol 9 (4-s) ◽

pp. 598-600

Author(s):

Shaik Salma

Keyword(s):

Rheumatoid Arthritis ◽

Case Report ◽

Cushing Syndrome ◽

Allergic Diseases ◽

Term Effect ◽

Long Term Effect ◽

Oral Hypoglycemics ◽

Steroid Drugs ◽

Buffalo Hump

Glucocorticoids are the effective steroid drugs which reduce the inflammation & most commonly glucocorticoids are used in diseases such as asthma, allergic diseases such as psoriasis, eczema and rheumatoid arthritis. Long term effect of corticosteroids leads to the symptoms of moon face, buffalo hump, pink stretch marks, and weight gain. In this we are going to report a case of 30 yrs female patient with representing the long term use of corticosteroids; Prednisolone leads to cushing syndrome. Eventually she was treated with oral hypoglycemics and diuretics and the use of steroid had stopped temporarily and the dose of prednisolone was tapered. Keywords: glucocorticoids, prednisolone, Cushing syndrome

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