Chronic uterine inversion with malignancy mimicking carcinoma cervix

Chronic non-puerperal uterine inversion is a rare event, with only a handful of cases reported in literature. We report a case of a 64-year-old postmenopausal woman who presented with complaints of mass per vaginam and postmenopausal bleeding. On examination, she appeared to have third-degree cervical descent with an irregular growth seen over what appeared to be the cervix, biopsy of which showed keratinising squamous cell carcinoma. Subsequently, an inverted uterus was diagnosed at laparotomy with an irregular growth seen over the inverted portion of the uterine fundus, histopathology of which revealed squamous cell carcinoma of endometrium.

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A PROSPECTIVE RANDOMIZED STUDY TO COMPARE THE CONCURRENT CHEMO-RADIATION VERSUS HYPO-FRACTIONATED CHEMO-RADIATION IN LOCALLY ADVANCED CERVICAL CANCER.

10.36106/ijar/8001653 ◽

2021 ◽

pp. 40-42

Author(s):

Arpan Jana ◽

Pabitra Das ◽

Poulami Gupta ◽

Phalguni Gupta

Keyword(s):

Cervical Cancer ◽

Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Squamous Cell ◽

External Beam Radiotherapy ◽

Locally Advanced ◽

Intracavitary Brachytherapy ◽

External Beam ◽

Carcinoma Cervix ◽

Advanced Carcinoma

Background: Concurrent chemo-radiation is the standard treatment worldwide for locally advanced squamous Cell carcinoma cervix. However, conventional chemo-radiotherapy is also associated with unacceptable local and systemic failure rates for locally advanced disease. Biologically squamous cell carcinoma of head- neck cancer and cervical cancer behaves quite similarly in response to radiotherapy. So, it can be expected that, altered fractionation can increase the local control in case of squamous cell carcinoma cervix than conventional radiotherapy. There is no randomised control trial for carcinoma cervix till date, which compares conventional chemo-radiation with hypo-fractionated chemo-radiation. Aims And Objectives: The present study was planned to compare local disease control and acute toxicity of conventional chemo-radiation with hypo-fractionated chemo-radiation in locally advanced carcinoma cervix. Materials And Methods: In Conventional Chemo-radiation Arm A patients (n=30) received external beam radiotherapy 50 Gy in 25 fractions in 5 weeks accompanied by weekly intravenous Cisplatin 40mg/m2 followed by intracavitary brachytherapy 7 Gy per fraction once in a week for 3 weeks. The second group of hypo-fractionated Arm B received external beam radiotherapy 45 Gy in 20 fractions in 4 weeks accompanied by weekly intravenous Cisplatin 40mg/m2 followed by intracavitary brachytherapy 9 Gy per fraction once in a week for 2 weeks. Results: Grade II diarrhea were seen more in Arm B 17 (56.66%) compare to Arm A 12(40%) and grade III diarrhea was seen 4 (3.33%) in Arm B and 2(6.66%) in Arm A. At 2 months and 6 months after completion of treatment Complete response were 25 (83.4%) in Arm A compare to 22 (73.3%) in Arm B and 20 (74.1%) in Arm A and 18 (72%) in Arm B respectively. Conclusion: Hypo-fractioned radiotherapy may be used as an alternate protocol for treatment of locally advanced carcinoma cervix with acceptable toxicities.

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Synchronous squamous cell carcinoma and papillary thyroid carcinoma arising from the thyroglossal duct remnant: Case report and a review of the literature

SAGE Open Medical Case Reports ◽

10.1177/2050313x20917846 ◽

2020 ◽

Vol 8 ◽

pp. 2050313X2091784

Author(s):

Marco Puccini ◽

Nicolò Roffi ◽

Valentina Pucci ◽

Giacomo Fiacchini ◽

Clara Ugolini ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Papillary Thyroid Carcinoma ◽

Thyroid Carcinoma ◽

Cell Carcinoma ◽

Squamous Cell ◽

Rare Event ◽

Papillary Thyroid ◽

Review Of The Literature ◽

Thyroglossal Duct ◽

Thyroglossal Duct Remnant

Squamous cell carcinoma and papillary thyroid carcinoma simultaneously spreading from the thyroglossal duct remnant (TGDR) is a very rare event. The recognition of this condition allows a correct management and treatment, offering the best chances of cure to the patient. We describe the case of a 42-year-old woman who noticed a right-sided lump in her neck. An ultrasound scan confirmed multiple clusters of enlarged lymph nodes on the right side associated to a pre-hyoidal solid nodule. The thyroid gland was normal. Fine-needle aspiration cytology on two nodes revealed distinct metastases from squamous cell carcinoma and from papillary thyroid carcinoma. A careful screening for other head and neck tumors was negative. She underwent a Sistrunk procedure, total thyroidectomy and right lateral lymphadenectomy with en bloc jugular vein resection. On histology, a 2 cm papillary and a small squamous cell carcinoma of the TGDR were documented, with nodal metastases from both primaries. We report the overall management strategy, treatment and outcome at 26-month follow-up, and a review of the literature.

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Postmenopausal bleeding: squamous cell carcinoma of cervix with coexisting endometrial tuberculosis

Archives of Gynecology and Obstetrics ◽

10.1007/s00404-003-0558-x ◽

2003 ◽

Vol 269 (3) ◽

pp. 221-223 ◽

Cited By ~ 6

Author(s):

Shalini Rajaram ◽

Geeta Dev ◽

Nirupma Panikar ◽

Kishor Chandra Singh ◽

Neerja Goel

Keyword(s):

Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Squamous Cell ◽

Postmenopausal Bleeding ◽

Carcinoma Of Cervix

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Unexpected Malignant Diagnosis in Colonic Biopsies: Malignant Transformation of Ovarian Mature Teratomas—Two Case Reports and Review of the Literature

Case Reports in Pathology ◽

10.1155/2015/905462 ◽

2015 ◽

Vol 2015 ◽

pp. 1-5 ◽

Cited By ~ 1

Author(s):

Claudia P. Rojas ◽

Parvin Ganjei-Azar ◽

Monica T. Garcia-Buitrago

Keyword(s):

Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Malignant Transformation ◽

Squamous Cell ◽

Case Reports ◽

Rare Event ◽

Cystic Teratoma ◽

The United States ◽

Colonic Biopsy ◽

Malignant Diagnosis

Colorectal adenocarcinoma is the second cause of cancer-related deaths in the United States. The occurrence of squamous cell carcinoma in the colorectum is extremely unusual. Malignant transformation from mature cystic teratoma of the ovary is a rare event. The most common transformation is squamous cell carcinoma, followed by adenocarcinoma. It occurs more often in elderly patients, who usually present with advance disease. We report two unusual cases of postmenopausal women diagnosed with squamous cell carcinoma in colon biopsies. After surgical resections, the carcinoma was proven to be the result of malignant transformation of ovarian mature cystic teratomas. Since squamous cell carcinoma of the colorectum is extremely rare, the presence of squamous cell carcinoma in a colonic biopsy in a female patient should alert the clinicians to other possible primary sites, as seen in these cases.

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Cisplatin versus gemcitabine as concurrent chemoradiotherapy in squamous cell carcinoma cervix: A comparative study of clinical response and toxicities

Journal of Cancer Research and Therapeutics ◽

10.4103/jcrt.jcrt_1184_20 ◽

2021 ◽

Vol 0 (0) ◽

pp. 0

Author(s):

Ramandeep Singh ◽

RajaParamjeet Singh Banipal ◽

LajyaDevi Goyal

Keyword(s):

Squamous Cell Carcinoma ◽

Comparative Study ◽

Cell Carcinoma ◽

Clinical Response ◽

Squamous Cell ◽

Concurrent Chemoradiotherapy ◽

Carcinoma Cervix

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Role of histopathological differentiation as a prognostic factor for treatment response in locally advanced squamous cell carcinoma cervix patients

Indian Journal of Medical and Paediatric Oncology ◽

10.4103/ijmpo.ijmpo_152_16 ◽

2018 ◽

Vol 39 (3) ◽

pp. 282 ◽

Cited By ~ 1

Author(s):

Pragya Shukla ◽

Afsana Shah ◽

NiharKanta Jena

Keyword(s):

Squamous Cell Carcinoma ◽

Prognostic Factor ◽

Cell Carcinoma ◽

Treatment Response ◽

Squamous Cell ◽

Locally Advanced ◽

Advanced Squamous Cell Carcinoma ◽

Carcinoma Cervix

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Pancreatic Squamous Cell Carcinoma

Case Reports in Gastroenterology ◽

10.1159/000448069 ◽

2017 ◽

Vol 11 (1) ◽

pp. 219-224 ◽

Cited By ~ 4

Author(s):

Seyed Hassan Abedi ◽

Alireza Ahmadzadeh ◽

Amir Houshang Mohammad Alizadeh

Keyword(s):

Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Squamous Cell ◽

Endoscopic Ultrasound ◽

Locally Advanced ◽

Survival Rates ◽

Rare Event ◽

Celiac Trunk ◽

Needle Aspiration ◽

Poor Survival

Pancreatic squamous cell carcinoma (SCC) is a rare event. Here, we present a 56-year-old man with pancreatic SCC. Imaging methods demonstrated a hypodense mass at the head and trunk of the pancreas. Also, some lymphadenopathy has been seen around the pancreas and para-aorta. The mass created pressure and encasement on the celiac trunk, portal vein, and arteries of the liver and spleen. Endoscopic ultrasound showed a mass lesion of 45–37 mm (mixed echoic) at the trunk of the pancreas. Histological examination of the endoscopic ultrasound-guided fine needle aspiration specimen confirmed the diagnosis of SCC. The disease is highly aggressive, most often locally advanced or metastatic at diagnosis, and poorly responsive to treatment. It also has generally poor survival rates.

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A CASE REPORT AND LITERATURE REVIEW: METACHRONOUS TUMOUR IN SINGLE PATIENT (CARCINOMA CERVIX AND CARCINOMA LUNG)

10.36106/ijsr/1501236 ◽

2021 ◽

pp. 33-34

Author(s):

Thamizholi S ◽

Ranu Chourasia ◽

Pearly Daimari ◽

Balakyntiew Kharshandi

Keyword(s):

Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Squamous Cell ◽

Systemic Chemotherapy ◽

Time Interval ◽

Lung Mass ◽

Single Patient ◽

Carcinoma Cervix ◽

Primary Tumors ◽

Ct Guided

INTRODUCTION: - Multiple primary tumors can be synchronous when detected simultaneously (or) metachronous when detected after a variable time interval. Association of two cancer in same patient is unusual but has been widely reported in the literature. CASE PRESENTAION: - A 55-year-old women was diagnosed in December 2018 as squamous cell carcinoma cervix FIGO STAGE IIIB & she received denitive chemoradiation 46GY/23# for 5 weeks with 5 cycles weekly injection carboplatin under AUC 2 followed by Brachytherapy and completed treatment in February 2019. She was on regular follow up till December 2020. Later she presented with upper back pain. She was evaluated for the same. CT Thorax suggestive of right upper lobe lung mass and PET- CT S/O Right Lung mass lesion with extension into spinal rd th canal & lytic destruction of D2/D3 Vertebrae and Right 3 , 4 rib. CT guided Biopsy s/o squamous cell carcinoma with IHC- p16 & p40-Positive, nd TTF-Negative and diagnosed as 2 primary carcinoma lung Stage IV. She received 6 cycles systemic chemotherapy completed in May 2021. She improved clinically & radiologically with systemic chemotherapy paclitaxel & carboplatin. CONCLUSION: - Metachronous tumor in single patient is unusual & management depends on stage of presentation.

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