scholarly journals Efficacy of colistimethate sodium as local application in necrotising fasciitis

2019 ◽  
Vol 12 (11) ◽  
pp. e232354
Author(s):  
Sreedutt Murali ◽  
Anoop V Pillai ◽  
Riju Ramachandran
Keyword(s):  
Subcutaneous Tissue ◽  
Cost Effective ◽  
Multidrug Resistant ◽  
Necrotising Fasciitis ◽  
Deep Fascia ◽  
Effective Treatment Modality ◽  
Cost Effective Treatment ◽  
Colistimethate Sodium ◽  
Local Use ◽  
Economic Constraints

Necrotising fasciitis (NF) is a rapidly progressive severe soft tissue infection of the deep fascia resulting in the destruction of overlying subcutaneous tissue and skin. We report the case of NF of the lower limb with a poor prognosis due to multidrug-resistant (MDR) Klebsiella pneumoniae (K.pneumoniae) sensitive only to colistin. In view of the worsening condition of the wound, risk of deterioration of renal function and economic constraints, it was decided to start on colistin therapy locally by colistimethate sodium (CMS). The patient responded well to the treatment and got clinically better. Subsequent culture sent for post-treatment showed no growth of the organism. The wound healed with regular dressings by 8 weeks. This was found to be a very cost-effective treatment modality. Local use of CMS was found to be a novel method of achieving infection-free wound especially against MDR K.pneumoniae.

Management of dental fluorosis by amodified treatment strategy amidst a global pandemic

2020 ◽  
Vol 12 (2) ◽  
pp. 46-49
Author(s):  
Dr Nileena Mary Cherian ◽  
Dr K. C Ponnappa ◽  
Dr SalinNanjappa ◽  
Dr K. K Nanjamma
Keyword(s):  
Case Report ◽  
Treatment Strategy ◽  
Treatment Modality ◽  
Dental Treatment ◽  
Dental Fluorosis ◽  
Cost Effective ◽  
Treatment Scenario ◽  
Global Pandemic ◽  
Effective Treatment Modality ◽  
Cost Effective Treatment

In recent months, the dental treatment scenario has changed due to the outbreak of the Covid 19 pandemic. Most of the aerosol generating procedures have been avoided. This case report, describes a conservative, less aerosol generating and cost-effective treatment modality, for the immediate aesthetic management of moderate fluorosis using enamel microabrasion technique.

The Patients’ Experiences of Telemedicine for their skin problems: A qualitative study in Singapore (Preprint)

2020 ◽  
Author(s):  
Aloysius Chow ◽  
Sok Huang Teo ◽  
Jing Wen Kong ◽  
Simon Biing Ming Lee ◽  
Yee Kiat Heng ◽  
...  
Keyword(s):  
Qualitative Study ◽  
Cost Effective ◽  
Management Plan ◽  
Dermatology Clinic ◽  
Effective Treatment Modality ◽  
Cost Effective Treatment ◽  
Rich Data ◽  
Patients Experience ◽  
Depth Interviews

BACKGROUND Teledermatology is a cost-effective treatment modality for the management of skin disorders. Most evaluations use quantitative data and far less is understood about the patients’ experience. OBJECTIVE This qualitative study explores patients’ perceptions of a teledermatology service linking public primary care clinics to the national specialist dermatology clinic in Singapore. A better understanding of patients’ experiences can help refine and develop the care provided. METHODS Semi-structured in-depth interviews were conducted with patients who had been referred to the teledermatology service. Interviews were digitally recorded and transcribed before undergoing thematic content analysis. RESULTS Twenty-one patients aged between 22 and 72 years were recruited. Three themes were identified from the data of patients’ experiences: positive perceptions of teledermatology, concerns about teledermatology, and ideas for improving the teledermatology service. Patients found the teledermatology service convenient, saving them time, expense and liberating them from the stresses incurred when making an in-person visit to a specialist facility. They valued the confidence and reassurance they gained from having a dermatologist involved in their management plan. Their concerns included data security and the quality of the images shared. Nonetheless, they were keen to see the service expanded beyond the polyclinics. Their experiences and perceptions will inform future service refinement and development. CONCLUSIONS This narrative exploration of users’ experiences of teledermatology produced rich data enabling a better understanding of the patient’s journey, the way they understand and interpret their experiences, and ideas for service refinement. Telemedicine reduces travelling and enables safe distancing, factors that are much needed during pandemics.

Patients with Sacroiliac Joint Pain and Arthritis

2016 ◽  
Author(s):  
Jianguo Cheng
Keyword(s):  
Sacroiliac Joint ◽  
Multimodal Therapy ◽  
Cost Effective ◽  
Surgical Approaches ◽  
Low Back ◽  
Multiple Modalities ◽  
Effective Treatment Modality ◽  
Cost Effective Treatment ◽  
Radiofrequency Denervation ◽  
Effectiveness Studies

Chronic pain originating from the sacroiliac joint (SIJ) is common. Pathophysiology is often related to biomechanical derangement affecting the SIJ or traumatic, degenerative, arthritic, and idiopathic changes of the SIJ. Diagnosis of SIJ pain is suggested by typical patterns of distribution, pain characteristics, and a combination of provocative tests, confirmed by diagnostic block of the SIJ, and differentiated from several other causes of low back pain. Multimodal therapy includes educational, physical, pharmacologic, interventional, and surgical approaches and should be individualized. The efficacy and safety of radiofrequency denervation of the sacroiliac joint have been demonstrated in randomized controlled trials. Multiple modalities of radiofrequency treatment exist, and comparative effectiveness studies are required to determine the most efficacious and cost-effective treatment modality. 

Patients with Sacroiliac Joint Pain and Arthritis

2016 ◽  
Author(s):  
Jianguo Cheng
Keyword(s):  
Sacroiliac Joint ◽  
Multimodal Therapy ◽  
Cost Effective ◽  
Surgical Approaches ◽  
Low Back ◽  
Multiple Modalities ◽  
Effective Treatment Modality ◽  
Cost Effective Treatment ◽  
Radiofrequency Denervation ◽  
Effectiveness Studies

Chronic pain originating from the sacroiliac joint (SIJ) is common. Pathophysiology is often related to biomechanical derangement affecting the SIJ or traumatic, degenerative, arthritic, and idiopathic changes of the SIJ. Diagnosis of SIJ pain is suggested by typical patterns of distribution, pain characteristics, and a combination of provocative tests, confirmed by diagnostic block of the SIJ, and differentiated from several other causes of low back pain. Multimodal therapy includes educational, physical, pharmacologic, interventional, and surgical approaches and should be individualized. The efficacy and safety of radiofrequency denervation of the sacroiliac joint have been demonstrated in randomized controlled trials. Multiple modalities of radiofrequency treatment exist, and comparative effectiveness studies are required to determine the most efficacious and cost-effective treatment modality. This review contains 1 highly rendered figure and 33 references.

scholarly journals Proposal for Establishing a New Radiotherapy Facility

2021 ◽  
pp. 41-55
Author(s):  
Mohamed Aldehaim ◽  
Jack Phan
Keyword(s):  
Cost Effective ◽  
Technical Aspect ◽  
Clinical Aspect ◽  
Patient Treatment ◽  
Treatment Needs ◽  
High Quality ◽  
Middle Income ◽  
Middle Income Countries ◽  
Effective Treatment Modality ◽  
Cost Effective Treatment

AbstractCancer is a growing burden globally. Radiotherapy has proven to be a critical and cost-effective treatment modality for a cure in greater than 50% of cancer patients. There are numerous obstacles and challenges in establishing new radiotherapy facilities and programs, especially in low- and middle-income countries. It is known that the clinical aspect, as well as procedure related to the physical and technical aspect of patient treatment, needs to be subjected to careful planning in order to ensure safe and high-quality radiotherapy. This process required the engagement of various professionals from different backgrounds.This chapter aims to define radiotherapy value, assessing a radiation facility’s clinical, infrastructure, and resources need to establish a new radiotherapy facility.

Regeneration and Repair of Skin Wounds: Various Strategies for Treatment

2019 ◽  
Vol 18 (3) ◽  
pp. 247-261 ◽  
Author(s):  
Fahimeh Rezaie ◽  
Madjid Momeni-Moghaddam ◽  
Hojjat Naderi-Meshkin
Keyword(s):  
Chronic Wounds ◽  
Cost Effective ◽  
Therapeutic Strategies ◽  
Skin Substitutes ◽  
Effective Treatment Modality ◽  
Cost Effective Treatment ◽  
Electrolyte Loss ◽  
Complex Wounds ◽  
Mechanical Barrier ◽  
Outer Environment

Skin as a mechanical barrier between the inner and outer environment of our body protects us against infection and electrolyte loss. This organ consists of 3 layers: the epidermis, dermis, and hypodermis. Any disruption in the integrity of skin leads to the formation of wounds, which are divided into 2 main categories: acute wounds and chronic wounds. Generally, acute wounds heal relatively faster. In contrast to acute wounds, closure of chronic wounds is delayed by 3 months after the initial insult. Treatment of chronic wounds has been one of the most challenging issues in the field of regenerative medicine, promoting scientists to develop various therapeutic strategies for a fast, qualified, and most cost-effective treatment modality. Here, we reviewed more recent approaches, including the development of stem cell therapy, tissue-engineered skin substitutes, and skin equivalents, for the healing of complex wounds.

scholarly journals Necrotising fasciitis after laparoscopic rectal cancer surgery

2017 ◽  
Vol 99 (4) ◽  
pp. e123-e124
Author(s):  
M Yiasemidou ◽  
S Majumder ◽  
M Basheer
Keyword(s):  
Rectal Cancer ◽  
Subcutaneous Tissue ◽  
Cancer Surgery ◽  
Necrotising Fasciitis ◽  
Deep Fascia ◽  
Rectal Cancer Surgery ◽  
First Case ◽  
Serious Infection ◽  
Low Threshold ◽  
Significant Mortality

Necrotising fasciitis is a rare, serious infection of the deep fascia leading to subcutaneous tissue necrosis. It is extremely important for this condition to be identified and treated promptly as it bears significant mortality. We describe a case of necrotising fasciitis after laparoscopic rectal cancer surgery. To our knowledge, this is the first case reported after the specific procedure. This case report aims to encourage surgeons to have a low threshold in recognising necrotising fasciitis postoperatively, especially for patients with possible risk factors.

Physical and Psychological Benefits of Written Emotional Expression

2015 ◽  
Vol 20 (4) ◽  
pp. 242-251 ◽  
Author(s):  
Éva Kállay
Keyword(s):  
Mental Health ◽  
Expressive Writing ◽  
Mental Health Problems ◽  
Cost Effective ◽  
Health Problems ◽  
Future Research ◽  
Psychological Benefits ◽  
Cost Effective Treatment ◽  
Meta Analyses

Abstract. The last several decades have witnessed a substantial increase in the number of individuals suffering from both diagnosable and subsyndromal mental health problems. Consequently, the development of cost-effective treatment methods, accessible to large populations suffering from different forms of mental health problems, became imperative. A very promising intervention is the method of expressive writing (EW), which may be used in both clinically diagnosable cases and subthreshold symptomatology. This method, in which people express their feelings and thoughts related to stressful situations in writing, has been found to improve participants’ long-term psychological, physiological, behavioral, and social functioning. Based on a thorough analysis and synthesis of the published literature (also including most recent meta-analyses), the present paper presents the expressive writing method, its short- and long-term, intra-and interpersonal effects, different situations and conditions in which it has been proven to be effective, the most important mechanisms implied in the process of recovery, advantages, disadvantages, and possible pitfalls of the method, as well as variants of the original technique and future research directions.

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