scholarly journals Challenging retrovesical mass in men: report of a rare liposarcoma case with concurrent COVID-19 infection

2021 ◽  
Vol 14 (3) ◽  
pp. e241466
Author(s):  
Indah Jamtani ◽  
Adianto Nugroho ◽  
Nur Rahadiani ◽  
R Semuel W Manangka

We describe a case of retrovesical liposarcoma in a male patient with concurrent COVID-19. A 50-year-old man had lower urinary tract symptoms and dull pain along his right gluteus. Due to COVID-19 infection, management was delayed. During self-isolation, the patient developed urinary retention and his pain level was an eight on the Visual Analogue Scale. A urinary catheter and an epidural catheter were inserted without any difficulty. Abdominal-pelvic MRI revealed a retrovesical mass suspected of liposarcoma with clear borders from surrounding organs. Following two consecutive negative SARS-CoV-2 PCR tests, we proceeded with surgery. Histopathology was dedifferentiated liposarcoma. Postoperatively, the patient suffered reactivation of COVID-19, and he was eventually discharged after two consecutive negative results on the PCR test on Post Operative Day (POD)-10. Retrovesical dedifferentiated liposarcoma is rare and considered as high-grade liposarcoma. Although surgery may exacerbate COVID-19 infection, surgical resection of symptomatic high-grade sarcoma is prioritised and performed as soon as no infection detected.

2020 ◽  
Vol 29 (2) ◽  
pp. 84-90
Author(s):  
Karen Logan

Intermittent self-catheterisation (ISC) is the method of choice for men with lower urinary tract symptoms who need to drain retained urine from the bladder. It is preferred to using an indwelling urinary catheter as it has lower risks of complications and catheter-associated urinary tract infection. Learning ISC can be challenging for men initially but, with the support of knowledgeable nurses experienced in teaching ISC, the technique can be learned, accepted and normalised, improving symptom control and quality of life. This paper discusses the results of a survey exploring men's experiences of learning ISC with the Hydrosil Go™ (C.R. Bard Inc—now part of Becton, Dickinson and Company) silicone catheter and to highlight issues important to men when learning and living with ISC. The survey collected data from four countries: UK, France, Netherlands and Italy. It aims to help nurses who teach ISC and inform them to discuss what matters to men when learning and living with ISC.


2005 ◽  
Vol 09 (01) ◽  
pp. 9-20 ◽  
Author(s):  
Meera R. Hameed ◽  
Tao-Zhen Lin ◽  
Frederick Coffman ◽  
Marion C. Cohen ◽  
Helen Fernandes ◽  
...  

The phenomenon of dedifferentiation typically occurs in soft tissue sarcomas where a low grade or well-differentiated tumor shows an abrupt transformation to a high-grade sarcoma without lineage specificity. The biological behavior and metastatic potential of these tumors is dictated by the dedifferentiated phenotype. Tumor material was available from two dedifferentiated liposarcomas. We performed cDNA microarray analysis of a dedifferentiated liposarcoma in which the atypical lipomatous/well-differentiated and dedifferentiated portions were grossly distinct, to find differentially expressed genes in the dedifferentiated component compared to the well-differentiated component. There were 100 differentially expressed genes, both up- and down-regulated in the high grade sarcoma. In addition, we performed RT-PCR on selected genes in both cases to confirm the microarray findings. We discuss the expression patterns of these genes in comparison to other studies in the literature.


2017 ◽  
Vol 26 (2) ◽  
pp. 174-179 ◽  
Author(s):  
Blake Hollowoa ◽  
Laura W. Lamps ◽  
Jason S. Mizell ◽  
George W. English ◽  
Julia A. Bridge ◽  
...  

Dedifferentiated liposarcoma is typically a nonlipogenic high-grade sarcoma that arises from well-differentiated liposarcoma. It most commonly presents as a large mass in the retroperitoneum. Significant involvement of the gastrointestinal tract by dedifferentiated liposarcoma is uncommon. We present a unique case of dedifferentiated liposarcoma radiographically mimicking a primary colon mass with resulting intussusception; stranding of the adjacent adipose tissue was presumed to be a secondary reactive change. On histopathologic analysis of the hemicolectomy specimen, a high-grade sarcoma was seen growing through the colonic wall, and the majority of the surrounding pericolonic adipose tissue was actually composed of well-differentiated liposarcoma with characteristic fibrous bands rather than benign fat with reactive fibrosis. This case raises awareness that well-differentiated liposarcoma and dedifferentiated liposarcoma can rarely present as a primary intestinal mass mimicking colon cancer or other more common entities. When radiographic examination shows a perigastrointestinal or retroperitoneal fatty mass and/or stranding of the fat adjacent to a solid gastrointestinal mass, this unusual scenario should be considered in the radiologic differential diagnosis. Pathologists should keep dedifferentiated liposarcoma in the initial histologic differential diagnosis for any high-grade spindle cell tumor of the retroperitoneum or intra-abdominal visceral organs.


2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Tarun Pradhan ◽  
Amit Deo ◽  
Raj Deb Mahato R ◽  
Tulasha Basnet

Aims: To study the pattern of LUTS during diagnostic cystoscopy and to evaluate patient’s satisfaction using rigid cystoscopy with intra-urethral lignocaine gel. Methods: Hospital based cross-sectional observational study done in all patients attending Department of Obstetrics and Gynecology with LUTS. Diagnostic cystoscopy was performed after using intra-urethral lignocaine gel. Patients profile and indications for cystoscopy were recorded; and VAS (Visual Analogue Scale) was used to assess procedure related pain. Data stored in MS Excel and descriptive analysis performed using SPSS 21. Result: Forty-three patients were included in the study. The mean age of presentation was 45.77 years. Majority of the patients were pre-menstrual and with symptoms less than 5 year duration. Twenty-seven (62.8%) patients had urgency as indication for cystoscopy followed by cystitis and recurrent urinary infection each (16.3%). Only 2 patients had mixed urinary incontinence. Thirty- one (72.1%) had mild discomfort, seven (18.7%) moderate and 5(9.2%)severe in visual analogue scale. Conclusions: Urgency was found to be a frequent indication for diagnostic cystoscopy and use of rigid cystoscope using inra-urethral gel showed only mild discomfort to majority of patients.


Sign in / Sign up

Export Citation Format

Share Document