scholarly journals Device-measured physical activity, adiposity and mortality: a harmonised meta-analysis of eight prospective cohort studies

2021 ◽  
pp. bjsports-2021-104827
Author(s):  
Jakob Tarp ◽  
Morten W Fagerland ◽  
Knut Eirik Dalene ◽  
Jostein Steene Johannessen ◽  
Bjørge H Hansen ◽  
...  
Keyword(s):  
Physical Activity ◽  
Mortality Risk ◽  
Sedentary Time ◽  
Meta Analysis ◽  
Vigorous Physical Activity ◽  
Total Activity ◽  
Normal Weight ◽  
Total Physical Activity ◽  
Risk Of Mortality

BackgroundThe joint associations of total and intensity-specific physical activity with obesity in relation to all-cause mortality risk are unclear.MethodsWe included 34 492 adults (72% women, median age 62.1 years, 2034 deaths during follow-up) in a harmonised meta-analysis of eight population-based prospective cohort studies with mean follow-up ranging from 6.0 to 14.5 years. Standard body mass index categories were cross-classified with sample tertiles of device-measured total, light-to-vigorous and moderate-to-vigorous physical activity and sedentary time. In five cohorts with waist circumference available, high and low waist circumference was combined with tertiles of moderate-to-vigorous physical activity.ResultsThere was an inverse dose–response relationship between higher levels of total and intensity-specific physical activity and mortality risk in those who were normal weight and overweight. In individuals with obesity, the inverse dose–response relationship was only observed for total physical activity. Similarly, lower levels of sedentary time were associated with lower mortality risk in normal weight and overweight individuals but there was no association between sedentary time and risk of mortality in those who were obese. Compared with the obese-low total physical activity reference, the HRs were 0.59 (95% CI 0.44 to 0.79) for normal weight-high total activity and 0.67 (95% CI 0.48 to 0.94) for obese-high total activity. In contrast, normal weight-low total physical activity was associated with a higher risk of mortality compared with the obese-low total physical activity reference (1.28; 95% CI 0.99 to 1.67).ConclusionsHigher levels of physical activity were associated with lower risk of mortality irrespective of weight status. Compared with obesity-low physical activity, there was no survival benefit of being normal weight if physical activity levels were low.

scholarly journals The Relationship of Accelerometer-Assessed Standing Time With and Without Ambulation and Mortality: The WHI OPACH Study

2020 ◽  
Vol 76 (1) ◽  
pp. 77-84
Author(s):  
Purva Jain ◽  
John Bellettiere ◽  
Nicole Glass ◽  
Michael J LaMonte ◽  
Chongzhi Di ◽  
...  
Keyword(s):  
Physical Activity ◽  
Mortality Risk ◽  
Sedentary Time ◽  
Vigorous Physical Activity ◽  
Community Dwelling ◽  
Machine Learning Algorithms ◽  
Cardiovascular Health Study ◽  
Accelerometer Data ◽  
All Cause Mortality

Abstract Background Self-reported time spent standing has been associated with lower risk of mortality. No previous studies have examined this association using device-measured standing. Method This was a prospective cohort study of 5878 older (median age = 80 years), racial/ethnically diverse, community-dwelling women in the WHI Objective Physical Activity and Cardiovascular Health Study (OPACH). Women wore accelerometers for 1 week and were followed for mortality. The study applied previously validated machine learning algorithms to ActiGraph GT3X+ accelerometer data to separately measure time spent standing with and without ambulation. Cox proportional hazards models were used to estimate mortality risk adjusting for potential confounders. Effect modification by age, body mass index, moderate-to-vigorous physical activity, sedentary time, physical functioning, and race/ethnicity was evaluated. Results There were 691 deaths during 26 649 person-years of follow-up through March 31, 2018 (mean follow-up = 4.8 years). In fully adjusted models, all-cause mortality risk was lower among those with more standing without ambulation (quartile [Q] 4 vs Q1 HR = 0.63; 95% CI = 0.49–0.81, p-trend = .003) and more standing with ambulation (Q4 vs Q1 HR = 0.50; 95% CI = 0.35–0.71, p-trend < .001). Associations of standing with ambulation and mortality were stronger among women with above-median sedentary time (HR = 0.51; 95% CI = 0.38–0.68) compared to women with below-median sedentary time (HR = 0.80; 95% CI = 0.59–1.07; p-interaction = .02). Conclusions In this prospective study among older women, higher levels of accelerometer-measured standing were associated with lower risks of all-cause mortality. Standing is an achievable approach to interrupting prolonged sedentary time, and if not contraindicated, is a safe and feasible behavior that appears to benefit health in older ages.

scholarly journals Accelerometry-assessed physical activity and sedentary time and associations with chronic disease and hospital visits - a prospective cohort study with 15 years follow-up

2019 ◽  
Vol 16 (1) ◽  
Author(s):  
Ing-Mari Dohrn ◽  
Anna-Karin Welmer ◽  
Maria Hagströmer
Keyword(s):  
Physical Activity ◽  
Cardiovascular Disease ◽  
Chronic Disease ◽  
Hospital Care ◽  
Sedentary Time ◽  
Vigorous Physical Activity ◽  
Population Based ◽  
Hospital Visits ◽  
Hospital Days

Abstract Background Associations of objectively assessed physical activity in different intensities and risk of developing chronic disease that requires hospital care have not yet been examined in long term population-based studies. Studies addressing the link between physical activity and sedentary time and subsequent hospital admissions are lacking. Objective To examine the prospective associations between physical activity and sedentary time with morbidity defined as: 1) a registered main diagnosis of cardiovascular disease, cancer, type-2 diabetes, dementia, obesity or depression; 2) number of in- and outpatient hospital visits; and 3) number of in-hospital days. Methods In total, 1220 women and men, 18–75 years, from the population-based Sweden Attitude Behaviour and Change study 2000–2001 were included. Time spent sedentary, in light-intensity physical activity and in moderate-to-vigorous physical activity, and total accelerometer counts were assessed using the ActiGraph 7164 accelerometer. Morbidity data were obtained 2016 from Swedish registers. Cox proportional hazards models estimated hazard ratios (HR) of morbidity with 95% confidence intervals (CI) and negative binomial regression estimated incidence rate ratio (IRR) with 95% CI for number of hospital visits, and length of hospital stay. Results Over a follow-up of 14.4 years (SD = 1.6), 342 persons had at least one registered hospital visit due to any of the included diagnoses. Higher moderate-to-vigorous physical activity was associated with significant risk reductions for combined morbidity (all included diagnoses) (HR: 0.65, 95% CI: 0.48–0.88) and cardiovascular disease (HR: 0.52, 95% CI: 0.33–0.82). Higher total counts showed similar results, and was also associated with fewer hospital visits (IRR = 0.56, 95% CI: 0.37–0.85). Higher sedentary time increased the risk of in-hospital days. (IRR = 2.38, 95% CI: 1.20–4.74). Conclusion This study supports the importance of moderate-to-vigorous physical activity for preventing chronic disease that requires hospital care, especially cardiovascular disease. High volumes of sedentary behavior may increase the risk of future hospitalization. Our results support the public health message “sit less and move more”.

scholarly journals Associations Between Home Environment and After-School Physical Activity and Sedentary Time Among 6th Grade Children

2015 ◽  
Vol 27 (2) ◽  
pp. 226-233 ◽  
Author(s):  
Erica Y. Lau ◽  
Daheia J. Barr-Anderson ◽  
Marsha Dowda ◽  
Melinda Forthofer ◽  
Ruth P. Saunders ◽  
...  
Keyword(s):  
Physical Activity ◽  
Home Environment ◽  
Parental Support ◽  
Physical Environment ◽  
Mixed Model ◽  
Sedentary Time ◽  
Vigorous Physical Activity ◽  
Total Physical Activity ◽  
After School ◽  
Time Availability

This study examined associations of various elements of the home environment with after-school physical activity and sedentary time in 671 6th-grade children (Mage = 11.49 ± 0.5 years). Children’s after-school total physical activity, moderate-to-vigorous physical activity, and sedentary time were measured by accelerometry. Parents completed surveys assessing elements of the home social and physical environment. Mixed-model regression analyses were used to examine the associations between each element of the home environment and children’s after-school physical activity and sedentary time. Availability of home physical activity resources was associated positively with after-school total physical activity and negatively with after-school sedentary time in boys. Parental support was associated positively with after-school total physical activity and MVPA and negatively with after-school sedentary time in girls. The home physical environment was associated with boys’ after-school physical activity and sedentary time, whereas the home social environment was associated with girls’ after-school physical activity and sedentary time.

Light-Intensity Physical Activity and All-Cause Mortality

2016 ◽  
Vol 31 (4) ◽  
pp. 340-342 ◽  
Author(s):  
Paul D. Loprinzi
Keyword(s):  
Physical Activity ◽  
Light Intensity ◽  
Mortality Risk ◽  
Weight Status ◽  
Vigorous Physical Activity ◽  
National Sample ◽  
Poverty Level ◽  
All Cause Mortality ◽  
Intensity Physical Activity

Purpose. Research demonstrates that moderate-to-vigorous physical activity (MVPA) is associated with a reduced risk of all-cause mortality. Few studies have examined the effects of light-intensity physical activity on mortality. Therefore, the purpose of this study was to examine the association between objectively measured light-intensity physical activity and all-cause mortality risk. Design. Longitudinal. Setting. National Health and Nutrition Examination Survey 2003–2006 with follow-up through December 31, 2011. Subjects. Five thousand five hundred seventy-five U.S. adults. Measures. Participants wore an accelerometer for at least 4 days and completed questionnaires to assess sociodemographics and chronic disease information, with blood samples taken to assess biological markers. Follow-up mortality status was assessed via death certificate data from the National Death Index. Analysis. Cox proportional hazard model. Results. After adjusting for accelerometer-determined MVPA, age, gender, race-ethnicity, cotinine, weight status, poverty level, C-reactive protein, and comorbid illness, for every 60-minute increase in accelerometer-determined light-intensity physical activity, participants had a 16% reduced hazard of all-cause mortality (hazard ratio = .84; 95% confidence interval: .78–.91; p < .001). Conclusion. In this national sample of U.S. adults, light-intensity physical activity was inversely associated with all-cause mortality risk, independent of age, MVPA, and other potential confounders. In addition to MVPA, promotion of light-intensity physical activity is warranted.

scholarly journals Cross-Sectional and Longitudinal Associations between Non-School Time Physical Activity, Sedentary Time, and Adiposity among Boys and Girls: An Isotemporal Substitution Approach

2021 ◽  
Vol 18 (9) ◽  
pp. 4671
Author(s):  
Kelsey L. McAlister ◽  
Jennifer Zink ◽  
Daniel Chu ◽  
Britni R. Belcher ◽  
Genevieve F. Dunton
Keyword(s):  
Physical Activity ◽  
Sedentary Time ◽  
Vigorous Physical Activity ◽  
Behavioral Approach ◽  
Cross Sectional ◽  
Time Activity ◽  
School Time ◽  
Longitudinal Associations ◽  
The Cross

This study investigated the cross-sectional and longitudinal associations of the substitution of non-school time light physical activity (LPA), moderate-to-vigorous physical activity (MVPA), and sedentary time (ST) with adiposity in boys and girls. Boys (n = 65, baseline Mage= 9.93 ± 0.86 years) and girls (n = 77, baseline Mage = 10.17 ± 0.95 years) wore waist-worn accelerometers (ActiGraph GT3X) at baseline and at a 30-month follow-up, from which non-school time LPA, MVPA, ST, and total device wear were quantified. Body mass index (BMI) and waist-to-height-ratio (WHR) were measured at baseline and follow-up. Body fat percent (BF%) was obtained at follow-up only. Isotemporal substitution models assessed the cross-sectional and longitudinal associations of reallocating non-school time activity with BMI, WHR and BF%. In boys, replacing 30 min/day of LPA with MVPA was cross-sectionally (β = −8.26, p < 0.05) associated with a lower BF%. Replacing 30 min/day of ST with MVPA was cross-sectionally (β = −6.02, p < 0.05) associated with a lower BF% in boys. Longitudinally in boys, replacing 30 min of change in LPA with MVPA (β = −7.42, p < 0.10) and replacing 30 min of change in MVPA with ST (β = 5.78, p < 0.10) over 30 months was marginally associated with less BF%. Associations were null in girls (p > 0.05). These results may support targeting activity reallocation during non-school time for the purposes of adiposity improvement in boys. A multi-behavioral approach may be more appropriate for girls, as non-school time activity may not be driving adiposity status.

scholarly journals Long-Term Correlates of Objectively Measured Physical Activity and Sedentary Time in Norwegian Men and Women

2015 ◽  
Vol 12 (11) ◽  
pp. 1500-1507 ◽  
Author(s):  
Ane Kristiansen Solbraa ◽  
Ulf Ekelund ◽  
Ingar M. Holme ◽  
Sidsel Graff-Iversen ◽  
Jostein Steene-Johannessen ◽  
...  
Keyword(s):  
Physical Activity ◽  
Sedentary Time ◽  
Vigorous Physical Activity ◽  
Perceived Health ◽  
Cross Sectional ◽  
Negatively Associated ◽  
Objectively Measured ◽  
Objectively Measured Physical Activity

Background:Sex, age, body mass index (BMI), perceived health and health behavior are correlates known to affect physical activity and sedentary time. However, studies have often been cross-sectional, and less is known about long-term correlates. Thus, the aims were to investigate 1) the associations between a set of characteristics (demographic, biological, psychological, and behavioral) and objectively measured physical activity and sedentary time at 13-year follow-up, and 2) the association between changes in these characteristics over time and physical activity and sedentary time.Methods:Baseline characteristics were collected in 40-year-olds in 1996, and follow-up data on objectively measured physical activity and sedentary time were obtained in 2009 (n = 240). Data were analyzed by multiple linear regressions.Results:Self-reported physical activity (P < .001) and improved perceived health (P = .046) were positively associated with moderate-to-vigorous physical activity (MVPA) whereas BMI (P = .034) and increased BMI (P = .014) were negatively associated with MVPA at follow-up. Women spent less time being sedentary than men (P = .019). Education (P < .001) was positively associated and improved perceived health (P = .010) was negatively associated with sedentary time at follow-up.Conclusions:MVPA and sedentary time at follow-up were associated with behavioral, biological and demographic correlates. However, the nature of our analyses prevents us from inferring causality.

scholarly journals Associations of vigorous physical activity with all-cause, cardiovascular and cancer mortality among 64 913 adults

2019 ◽  
Vol 5 (1) ◽  
pp. e000596 ◽  
Author(s):  
Juan Pablo Rey Lopez ◽  
Klaus Gebel ◽  
Debbie Chia ◽  
Emmanuel Stamatakis
Keyword(s):  
Physical Activity ◽  
Health Survey ◽  
Mortality Risk ◽  
Cancer Mortality ◽  
Vigorous Physical Activity ◽  
Epidemiological Studies ◽  
Moderate Intensity ◽  
Vigorous Activity ◽  
Scottish Health Survey

BackgroundPhysical activity recommendations state that for the same energy expenditure, moderate-to-vigorous physical activities (MVPAs) produce similar health benefits. However, few epidemiological studies have tested this hypothesis.DesignWe examined whether, compared with moderate, vigorous activity was associated with larger mortality risk reductions.MethodsData from 11 cohorts of the Health Survey for England and the Scottish Health Survey, collected from 1994 to 2011 (mean (SD) follow-up, 9.0 (3.6) years). Adults aged ≥30 years reported MVPA and linkage to mortality records. Exposure was the proportion of self-reported weighted MVPA through vigorous activity. Outcomes were all-cause, cardiovascular disease (CVD) and cancer mortality.ResultsAmong 64 913 adult respondents (44% men, 56% women, mean (SD) age, 49.8 (13.6) years), there were 5064 deaths from all-causes, 1393 from CVD and 1602 from cancer during 435 743 person-years of follow-up. Compared with those who reported no vigorous physical activity, and holding constant the volume of weighted MVPA, vigorous activity was associated with additional reductions in mortality risk. For all-cause mortality, the adjusted HR was HR=0.84 (95% CI 0.71, 0.99) and HR=0.84 (95% CI 0.76, 0.94) among those who reported between >0% and<30%, or ≥30% of their activity as vigorous, respectively. For CVD and cancer mortality, point estimates showed similar beneficial associations yet CIs were wider and crossed unity.ConclusionVigorous activities were associated with larger reductions in mortality risk than activities of moderate intensity, but no evidence of dose–response effects was found.

Replacing Sedentary Time With Light or Moderate–Vigorous Physical Activity Across Levels of Frailty

2020 ◽  
Vol 28 (1) ◽  
pp. 18-23 ◽  
Author(s):  
Judith Godin ◽  
Joanna M. Blodgett ◽  
Kenneth Rockwood ◽  
Olga Theou
Keyword(s):  
Physical Activity ◽  
Sedentary Behavior ◽  
Mortality Risk ◽  
Sedentary Time ◽  
Vigorous Physical Activity ◽  
Frailty Index ◽  
Lower Mortality ◽  
Vigorous Exercise ◽  
Light Activity ◽  
Lower Mortality Risk

The authors sought to examine how much sedentary time needs to be replaced by light or moderate–vigorous physical activity in order to reduce frailty and protect against mortality. The authors built isotemporal substitution models to assess the theoretical effect of replacing sedentary behavior with an equal amount of light or moderate–vigorous activity on frailty and mortality in community-based adults aged 50 years and older. Controlling for age, sex, body mass index, marital status, race, education, employment status, and National Health and Nutrition Examination Study cycle, replacing 1 hr of sedentary time with moderate–vigorous or light physical activity daily was associated with a lower frailty index. For mortality, results varied based on frailty level. Replacing sedentary behavior with moderate–vigorous exercise was associated with lower mortality risk in vulnerable individuals; however, replacing sedentary behavior with light activity was associated with lower mortality risk in frailer individuals.

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