scholarly journals The cross-sectional association of sitting time with carotid artery stiffness in young adults

BMJ Open ◽  
2014 ◽  
Vol 4 (3) ◽  
pp. e004384 ◽  
Author(s):  
Quan L Huynh ◽  
Christopher L Blizzard ◽  
James E Sharman ◽  
Costan G Magnussen ◽  
Terence Dwyer ◽  
...  
Keyword(s):  
Young Adults ◽  
Carotid Artery ◽  
Sitting Time ◽  
Cross Sectional ◽  
Artery Stiffness ◽  
The Cross

Abstract 081: Obesity-related Reductions in Cardiac Baroreflex Sensitivity and Higher 24-hour Blood Pressure Variability Are Not Related to Carotid Artery and Aortic Stiffness in Young And Middle-aged Adults

Hypertension ◽  
2016 ◽  
Vol 68 (suppl_1) ◽  
Author(s):  
Seth Holwerda ◽  
Jess Fiedorowicz ◽  
Lyndsey DuBose ◽  
Amy Stroud ◽  
Tiwa Ajibewa ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Carotid Artery ◽  
Blood Pressure Variability ◽  
Aortic Stiffness ◽  
Baroreflex Sensitivity ◽  
Normal Weight ◽  
Middle Aged ◽  
Cvd Risk ◽  
Cross Sectional ◽  
Artery Stiffness

Alterations in cardiac baroreflex sensitivity (BRS) and 24-hr blood pressure variability (24-hr BPV) are independent predictors of increased cardiovascular disease (CVD) risk, and occur in individuals with obesity. Obese humans are also likely to have a higher large elastic artery stiffness compared with normal-weight individuals. While an increase in stiffness of carotid and aortic arteries, the anatomical sites where baroreceptors reside, may likely be responsible in part for the decline in cardiac BRS with advancing age in adults, it remains unclear whether 1) elevated carotid and aortic stiffness are also directly associated with obesity-associated reductions in cardiac BRS in young/middle-aged individuals, and 2) if reduced BRS with obesity is associated with elevated 24hr BPV. We tested the hypothesis that lower BRS would be associated with higher carotid and aortic stiffness and 24hr BPV in young and middle-aged individuals with obesity. In a cross-sectional design, 22 normal-weight (body mass index, BMI 24.5 ± 0.6 kg/m 2 ; age 35±2 yrs; 8M/14F) and 22 obese (BMI 34.2 ± 1.1 kg/m 2 ; age 39 ± 2 yrs; 8M/14F) individuals underwent measures of spontaneous cardiac BRS (sequence technique), carotid artery β-stiffness (carotid tonometry and B-mode ultrasound of common carotid artery), aortic stiffness (carotid-femoral pulse wave velocity, CFPWV), and 24-hr-systolic BPV (24 hr ambulatory BP monitoring). A significant relation between cardiac BRS and 24-hr systolic BPV (r=-0.42, P<0.01) was corroborated by lower cardiac BRS (11.7±1.2 vs. 16.8±1.7 ms/mmHg, P<0.05) and higher 24-hr BPV (12.4±0.6 vs. 10.1±0.4 mmHg SD, P<0.05) among obese compared with normal-weight subjects. In contrast, carotid β-stiffness (7.8±0.6 vs. 6.9±0.4 U, P>0.05) and CFPWV (745±71 vs. 611±19 cm/s, P=0.07) were not significantly different between groups despite greater average 24-hr systolic BP in the obese vs. normal weight subjects (127±2 vs. 118±1 mmHg, P<0.05). These preliminary data suggest that an increase in carotid artery and aortic stiffness may not precede the decline in cardiac BRS and increase in 24hr BPV in young and middle-aged obese individuals, suggesting non-arterial stiffness related mechanisms for obesity-related reductions in cardiac BRS.

Correlates of carotid artery stiffness in young adults: The Bogalusa Heart Study

2004 ◽  
Vol 176 (1) ◽  
pp. 157-164 ◽  
Author(s):  
E.M Urbina ◽  
S.R Srinivasan ◽  
R.L Kieltyka ◽  
R Tang ◽  
M.G Bond ◽  
...  
Keyword(s):  
Young Adults ◽  
Carotid Artery ◽  
Bogalusa Heart Study ◽  
Heart Study ◽  
Artery Stiffness

Common Carotid Artery Flow Parameters Predict the Incidence of Hypertension

Hypertension ◽  
2021 ◽  
Vol 78 (6) ◽  
pp. 1711-1718
Author(s):  
Nobuo Sasaki ◽  
Ryo Maeda ◽  
Ryoji Ozono ◽  
Yukiko Nakano ◽  
Yukihito Higashi
Keyword(s):  
Carotid Artery ◽  
Common Carotid Artery ◽  
Cohort Analysis ◽  
Resistance Index ◽  
Cross Sectional ◽  
Incident Hypertension ◽  
Cross Sectional Analysis ◽  
Flow Parameters ◽  
The Cross ◽  
Sectional Analysis

The resistance index (RI) and pulsatility index (PI) in the common carotid artery (CCA) reflect vascular resistance and aortic stiffness. We investigated the association of these CCA flow parameters with the prevalence and incidence of hypertension, with comparison to the intima-media thickness (IMT). The cross-sectional analysis included 2660 participants who underwent carotid artery ultrasonography. Of those, 1249 normotensive participants at baseline were enrolled in the retrospective cohort analysis. A high RI, high PI, and increased IMT were indicated based on the optimal cutoff values in a receiver operating characteristic curve analysis. RI (β=0.158, P <0.001) and PI (β=0.130, P <0.001) were significantly associated with systolic blood pressure in the cross-sectional analysis. Over a mean 5.1-year follow-up period, 524 participants developed hypertension. A high RI (odds ratio [OR], 1.65; P <0.001), high PI (OR, 1.63; P <0.001), and increased IMT (OR, 1.40; P =0.017) were significant predicators for incident hypertension. Combining IMT and the PI, a high PI alone (OR, 1.52; P =0.008) was a significant predicator for incident hypertension, whereas increased IMT alone was not significantly associated with the risk of hypertension. The group with both increased IMT and a high PI had the highest risk of hypertension (OR, 2.24; P <0.001). Similar results were obtained from the analysis of IMT and RI, suggesting that CCA parameters evaluated by ultrasonography may help identify individuals at high risk of hypertension. In particular, CCA flow parameters are better predictors.

scholarly journals Carotid artery stiffness in rural adult Chinese: a cross-sectional analysis of the community-based China stroke cohort study

BMJ Open ◽  
2020 ◽  
Vol 10 (10) ◽  
pp. e036398
Author(s):  
Yao Wei ◽  
Ming Wang ◽  
Yang Gui ◽  
Xuemei Piao ◽  
Conghui Sun ◽  
...  
Keyword(s):  
Cohort Study ◽  
Carotid Artery ◽  
Arterial Stiffness ◽  
Secondary Outcome ◽  
Community Based ◽  
Cross Sectional ◽  
Cross Sectional Analysis ◽  
Physical Measurements ◽  
Artery Stiffness ◽  
Sectional Analysis

ObjectivesTo derive normative carotid artery stiffness data in rural adult Chinese population-based study of ultrasound measurements of carotid elasticity by using quality arterial stiffness (QAS), and to assess the changes of relevant parameters in Chinese adults 40 years of age and older.DesignA China stroke cohort study (total number: 1586) in the northern countryside were carried out between June 2013 and April 2016, designed to investigate the risk factors of cardiovascular and age-related diseases.SettingThe present study was a cross-sectional analysis of an ongoing community-based Shunyi cohort study in China.ParticipantsA total of 583 participants (227 men and 356 women; aged 40–80 years) with ultrasound carotid QAS examination were retrieved from the study to analyse.Primary and secondary outcome measuresArterial stiffness parameters included diastolic diameter (Dd), pulse wave velocity (PWV), stiffness indices α and β were calculated by QAS. Other clinical indicators included physical measurements, medical histories and blood biochemical test.ResultsIn the entire study sample, mean Dd was 7.93±0.88 mm, mean PWV was 9.4±2.4 m/s, mean α was 7.65±5.13 and mean β was 15.53±10.29. PWV was significant higher in participants with hypertension (9.9 m/s vs 9.2 m/s in those without, p=0.002), and with diabetes (10.3 m/s vs 9.2 m/s in those without, p=0.003). PWV were significantly higher in participants with HbA1c at 5.8%–6.4% versus <5.8%, but no difference was found between subjects with glycohaemoglobin (HbA1c) at 5.8%–6.4% versus >6.4% (p=0.005, p=0.955, respectively). Age increase by every 10 years was associated with Dd increased by 0.27 mm, PWV increased by 1.2 m/s, α increased by 1.34 and β increased by 2.71. Systolic blood pressure (SBP) increase by every 10 mm Hg was associated with Dd increased by 0.15 mm, PWV increased by 0.35 m/s, α increased by 0.13 and β increased by 0.15.ConclusionAmong the participants older than 40 years, stiffness of the carotid artery had differences between hypertension and non-hypertension adults, as well as between diabetes and non-diabetes adults. Stiffness of the carotid artery also have differences between adults with HbA1c at 5.8%–6.4% versus <5.8%. Stiffness of the carotid artery increases with increasing age and increasing SBP at a range from 40 and up.

scholarly journals Distribution and Cross-Sectional Age-Related Increases of Carotid Artery Intima-Media Thickness in Young Adults

Stroke ◽  
2004 ◽  
Vol 35 (12) ◽  
pp. 2782-2787 ◽  
Author(s):  
James H. Stein ◽  
Pamela S. Douglas ◽  
Sathanur R. Srinivasan ◽  
M. Gene Bond ◽  
Rong Tang ◽  
...  
Keyword(s):  
Young Adults ◽  
Carotid Artery ◽  
Intima Media Thickness ◽  
Cross Sectional ◽  
Media Thickness ◽  
Age Related

Analysis of the positional relationship between the left brachiocephalic vein and its surrounding vessels via computed tomography scan: A retrospective study

2020 ◽  
Vol 35 (6) ◽  
pp. 416-423
Author(s):  
Hiroki Mitsuoka ◽  
Takahiro Arima ◽  
Yusuke Ohmichi ◽  
Munekazu Naito ◽  
Makiyo Hagihara ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Carotid Artery ◽  
Common Carotid Artery ◽  
Left Subclavian Artery ◽  
Left Common Carotid Artery ◽  
Brachiocephalic Vein ◽  
Brachiocephalic Artery ◽  
Cross Sectional ◽  
Left Brachiocephalic Vein ◽  
The Cross

Objectives This study aimed to clarify the positional relationship between the left brachiocephalic vein and its surrounding vessels and to analyse the association between this positional relationship and ageing. Method Chest contrast-enhanced computed tomography was performed for 100 adults. The contact number between left brachiocephalic vein and surrounding vessels (aorta, brachiocephalic artery, left common carotid artery and left subclavian artery) was determined. The correlations of ageing with the cross-sectional areas of left brachiocephalic vein crossing brachiocephalic artery and left common carotid artery and peripheral end of left brachiocephalic vein were analysed. Results LBV was in contact with aorta in 19, brachiocephalic artery in 97, left common carotid artery in 90 and left subclavian artery in 21 patients. There were significant negative correlations of ageing with the cross-sectional areas of left brachiocephalic vein crossing brachiocephalic artery and left common carotid artery and peripheral end of left brachiocephalic vein. Conclusions Brachiocephalic artery and left common carotid artery have easy contact with left brachiocephalic vein. There was a negative relationship between the cross-sectional area of left brachiocephalic vein and age.

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