scholarly journals Assessing oral medication adherence among patients with type 2 diabetes mellitus treated with polytherapy in a developed Asian community: a cross-sectional study

BMJ Open ◽  
2017 ◽  
Vol 7 (9) ◽  
pp. e016317 ◽  
Author(s):  
Cia Sin Lee ◽  
Jane Hwee Mian Tan ◽  
Usha Sankari ◽  
Yi Ling Eileen Koh ◽  
Ngiap Chuan Tan
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Medication Adherence ◽  
Glycaemic Control ◽  
Univariate Analysis ◽  
Vascular Complications ◽  
Cross Sectional ◽  
Chinese Ethnicity

ObjectivesThe disease burden of type 2 diabetes mellitus (T2DM) is rising due to suboptimal glycaemic control leading to vascular complications. Medication adherence (MA) directly influences glycaemic control and clinical consequences. This study aimed to assess the MA of patients with T2DM and identify associated factors.DesignAnalysis of data from a cross-sectional survey and electronic medical records.SettingPrimary care outpatient clinic in Singapore.ParticipantsAdult patients with T2DM.Main outcome measuresMA to each prescribed oral hypoglycaemic agent (OHA) was measured using the five-question Medication Adherence Report Scale (MARS-5). Low MA is defined as a MARS-R score of <25. Demographic data, clinical characteristics and investigation results were collected to identify factors that are associated with low MA.ResultsThe study population comprised 382 patients with a slight female predominance (53.4%) and a mean±SD age of 62.0±10.4 years. 57.1% of the patients had low MA to at least one OHA. Univariate analysis showed that patients who were younger, of Chinese ethnicity, married or widowed, self-administering their medications or taking fewer (four or less) daily medications tended to have low MA to OHA. Logistic regression revealed that younger age (OR 0.97; 95% CI 0.95 to0.99), Chinese ethnicity (OR 2.80; 95% CI 1.53 to5.15) and poorer glycaemic control (HbA1c level) (OR 1.27; 95% CI 1.06 to1.51) were associated with low MA to OHA.ConclusionsYounger patients with T2DM and of Chinese ethnicity were susceptible to low MA to OHA, which was associated with poorer glycaemic control. Polytherapy was not associated with low MA.

scholarly journals Medication Adherence Analysis of Type 2 Diabetes Mellitus Patients

2019 ◽  
Vol 1 (3) ◽  
pp. 107
Author(s):  
Sulistyo Andarmoyo ◽  
Harmy Bin Mohamed Yusoff ◽  
Berhanudin Bin Abdullah ◽  
Yuzana Binti Mohd Yusop
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Medication Adherence ◽  
Sex Education ◽  
Service Management ◽  
Health Care Facilities ◽  
Improve Medication Adherence ◽  
Cross Sectional

Adherence has an important role in therapy management in patients with type 2 Diabetes Mellitus. This research is to identify and analyze factors related to medication adherence. The design used in this study was a descriptive-analytic design with a cross-sectional approach. The population is type 2 Diabetes Mellitus sufferers of Prolanis Group in Primary Health Care Facilities in the Ponorogo Regency. A sample of 180 respondents was taken by purposive sampling technique. Variable X includes age, gender, education, occupation, income, and length of suffering. Variable Y was medication compliance with type 2 Diabetes Mellitus patients. Data collection used a Morisky Medication Adherence (MMAS-8) questionnaire and was analyzed using the Chi-Square test with a significant level of α <0.05. From the results of the study, it was found that the factors of age, sex, education, employment, income and duration of suffering had a significant relationship with medication adherence for patients with type 2 diabetes mellitus. It is expected that health services develop family and community-based service management. Researchers are further advised to develop programs to improve medication adherence.

scholarly journals Oral antidiabetic medication adherence and glycaemic control among patients with type 2 diabetes mellitus: a cross-sectional retrospective study in a tertiary hospital in Saudi Arabia

BMJ Open ◽  
2019 ◽  
Vol 9 (7) ◽  
pp. e029280 ◽  
Author(s):  
Bander Balkhi ◽  
Monira Alwhaibi ◽  
Nasser Alqahtani ◽  
Tariq Alhawassi ◽  
Thamir M Alshammari ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Saudi Arabia ◽  
Glycaemic Control ◽  
Tertiary Hospital ◽  
Good Adherence ◽  
Cross Sectional ◽  
Oral Antidiabetic

ObjectivesThe purpose of this study is to measure the adherence rates of oral antidiabetic drugs (OADs) in patients with type 2 diabetes mellitus (T2DM) and assess the relationship of glycaemic control and adherence to OADs after controlling for other associated factors.DesignCross-sectional retrospective study.SettingLarge tertiary hospital in the central region of Saudi Arabia.Participants5457patients aged 18 years and older diagnosed with T2DM during the period from 1 January 2016 to 31 December 2016.Primary and secondary outcome measuresThe modified medication possession ratio (mMPR) was calculated as a proxy measure for adherence of OADs. The factors associated with OADs non-adherence and medication oversupply were assessed using multinomial logistic regression models. The secondary outcomes were to measure the association between OADs adherence and glycaemic control.ResultsMajority of patients with T2DM were females (n=3400, 62.3%). The average glycated haemoglobin was 8.2±1.67. Among the study population, 48.6% had good adherence (mMPR >0.8) and 8.6% had a medication oversupply (mMPR >1.2). Good adherence was highest among those using repaglinide (71.0%) followed by pioglitazone (65.0%) and sitagliptin (59.0%). In the multivariate analysis, women with T2DM were more likely to have poor adherence (adjusted OR (AOR)=0.76, 95% CI=0.67, 0.86) compared with men. Also, medication oversupply was more likely among patients with hyperpolypharmacy (AOR=1.88, 95% CI=1.36, 2.63), comorbid osteoarthritis (AOR=1.72, 95% CI=1.20, 02.45) and non-Saudi patients (AOR=1.53, 95% CI=1.16, 2.01). However, no association was found between glycaemic control and adherence to OADs.ConclusionThe study findings support the growing concern of non-adherence to OADs among patients with T2DM in Saudi Arabia. Decision makers have to invest in behavioural interventions that will boost medication adherence rates. This is particularly important in patients with polypharmacy and high burden of comorbid conditions.

scholarly journals Overview of glomerulus filtration in type 2 of diabetes mellitus at Sanjiwani Gianyar hospital year of 2018-2019

2021 ◽  
Vol 4 (1) ◽  
pp. 50-55
Author(s):  
Putu Ayu Indah Saraswati ◽  
I Made Kasmadi Gunawan ◽  
Dewa Gde Agung Budiyasa
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Univariate Analysis ◽  
Secondary Data ◽  
Cross Sectional ◽  
Descriptive Research ◽  
Grade 5 ◽  
Grade 3

This study used a descriptive research design with a cross-sectional approach. This research was conducted at RSUD Sanjiwani Gianyar which was conducted from July to November 2019. The sample taken in this study must meet the inclusion criteria. This study uses secondary data in the form of patient medical records at Sanjiwani Gianyar Regional Hospital in 2018-2019. The research variables consisted of independent variables in the form of glomerular filtration rate and dependent variables in the form of type 2 diabetes mellitus patients. Data processing and analysis were carried out using computerized techniques with computer devices. Data analysis was carried out using univariate analysis used to analyze descriptively by calculating the frequency distribution of each research variable. The results of the research of 50 people with type 2 diabetes mellitus, the majority of respondents of LFG grade were grade 3 with a total of 18 people (36.0%) and grade 1 as many as 15 people (30.0%), while the lowest was grade 4 with a total of 2 (4.0%) and grade 5 as many as 3 people (6.0%).

scholarly journals ASSOCIATION OF HYPOTHYROIDISM WITH MICROVASCULAR COMPLICATIONS AMONG PATIENTS OF TYPE-2 DIABETES MELLITUS

2021 ◽  
Vol 5 (12) ◽  
Author(s):  
Krishan Kumar Meena ◽  
Praveen Sharma ◽  
Swati Srivastava ◽  
Uma Kumari Meena
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Microvascular Complications ◽  
Vascular Complications ◽  
Vascular Complication ◽  
Cross Sectional ◽  
Type 2 Dm ◽  
Hypothyroid Patients

Introduction: Diabetes mellitus (DM) is common metabolic disorder leading to various complications including micro-vascular complication. Diabetes and thyroid dysfunction can result in abnormalities of one another, as both are strongly implicated in cellular metabolism.  Aim of study was to establish any association between hypothyroidism and micro-vascular complications in patients of type 2 DM. Material and Methods: This Hospital based Cross sectional analytical Study was included 80 Euthyroid and 80 hypothyroid patients of type 2 DM. These patients were subjected to fundus examination (for retinopathy), urine for spot albumin and creatinine ratio and routine microscopy (for nephropathy), clinical examination and NCV (for neuropathy). Results: Age of patients ranged from 30 – 80 years. Most patients had duration of Diabetes > 5 years. Diabetic retinopathy was found in 15% Euthyroid and 37.5% Hypothyroid diabetics (p=0.002). Neuropathy was more in Hypothyroid (35%) as compared to Euthyroid (12.5%) patients (p=0.003). Prevalence of Nephropathy was also significantly more (p=0.011) in Hypothyroids (60%) as compared to Euthyroid (38.75%). Conclusion: Significant association was found between hypothyroidism and micro vascular complications in type 2 Diabetes mellitus. Screening of diabetics for thyroid functions is essential to reduce morbidity. Keywords: Diabetes, thyroid, retinopathy, neuropathy, nephropathy

scholarly journals Health literacy and adherence to drug treatment of type 2 diabetes mellitus

2019 ◽  
Vol 23 (2) ◽  
Author(s):  
Mariana Rodrigues da Rocha ◽  
Sinderlândia Domingas dos Santos ◽  
Karine Rafaela de Moura ◽  
Lesliane de Sousa Carvalho ◽  
Ionara Holanda de Moura ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Medication Adherence ◽  
Health Literacy ◽  
Drug Treatment ◽  
Functional Health ◽  
Cross Sectional ◽  
Sociodemographic Variables

ABSTRACT Objective: To analyze the relationship between health literacy and medication adherence of patients with Type 2 Diabetes Mellitus. Method: Quantitative cross-sectional study developed in five Family Health Strategies in the city of Picos, Piauí. Participants comprised 78 users of health services. The “Short Test of Functional Health Literacy in Adults” and the “Treatment Adherence Measurement Test” forms were applied to obtain sociodemographic variables. Descriptive and inferential statistical analysis. Results: Regarding health literacy, 51.3% of the participants were considered inadequate, and 87.2% were adherent to the drug treatment. The average of health literacy varied according to the level of medication adherence and sociodemographic variables. Conclusion: Most patients reported to adhere to the medication. Implications for practice: This study identified the health literacy and medication adherence profile of the patients, thus subsidizing the planning of nursing interventions in the attention of diabetes mellitus.

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