scholarly journals Associations of health literacy with risk factors for diabetic foot disease: a cross-sectional analysis of the Southern Tasmanian Health Literacy and Foot Ulcer Development in Diabetes Mellitus Study

BMJ Open ◽  
2019 ◽  
Vol 9 (7) ◽  
pp. e025349 ◽  
Author(s):  
Pamela Chen ◽  
Michele Callisaya ◽  
Karen Wills ◽  
Tim Greenaway ◽  
Tania Winzenberg
Keyword(s):  
Risk Factors ◽  
Health Literacy ◽  
Diabetic Foot ◽  
Short Form ◽  
Functional Health ◽  
Cross Sectional ◽  
Cross Sectional Analysis ◽  
Diabetic Foot Disease ◽  
Foot Disease ◽  
Sectional Analysis

ObjectivesPoor health literacy (HL) is associated with poorer health outcomes in diabetes but little is known about its effects on foot disease. This study was aimed to determine the associations between HL and diabetic foot disease.DesignThis is a cross-sectional analysis of baseline data from a prospective study of foot disease.SettingAttendees of the Royal Hobart Hospital’s Diabetes outpatient clinics.Participants222 people with type 1 or type 2 diabetes aged >40 years and without a history of foot disease, psychotic disorders or dementia.MeasuresOutcomes were peripheral neuropathy, peripheral arterial disease and foot deformity according to published guidelines. The exposure, HL, was measured using the short form Test of Functional Health Literacy in Adults (S-TOFHLA) and the Health Literacy Questionnaire (HLQ). Covariates included demographic characteristics, medical history, psychological measures and foot care behaviour.ResultsOf 222 participants, 204 had adequate HL. (Mean (SD) S-TOFHLA scores were 31.9 (6.7)), mean(SD) HLQ scores were 134.4 (18.4)). In univariable but not multivariable analyses, higher S-TOFHLA scores were associated with lower overall risk for foot disease (OR 0.96, 95% CI 0.93 to 0.99) and loss of protective sensation (OR 0.95, 95% CI 0.91 to 0.995).ConclusionsThese data provide little support for clinically important impacts of HL on risk factors for diabetic foot disease. However, in the absence of longitudinal data, such effects cannot be ruled out. Longitudinal studies measuring incident foot disease are needed to properly judge the potential for interventions improving HL to reduce the incidence of diabetic foot disease.

scholarly journals Prevalence and Risk Factors Associated With Hypertension in Hemophilia: Cross-Sectional Analysis of a National Discharge Register

2016 ◽  
Vol 23 (7) ◽  
pp. 871-875 ◽  
Author(s):  
Craig D. Seaman ◽  
Mariya Apostolova ◽  
Jonathan Yabes ◽  
Diane M. Comer ◽  
Margaret V. Ragni
Keyword(s):  
Risk Factors ◽  
Cross Sectional ◽  
Factors Associated ◽  
Cross Sectional Analysis ◽  
Sectional Analysis

Clinical and Microbiological Profile of Diabetic Foot Ulcers Infected With Staphylococcus aureus in a Regional General Hospital in Bahia, Brazil

2021 ◽  
pp. 153473462110507
Author(s):  
Luciano Dias Nascimento ◽  
Arthur César Pacheco Lopes ◽  
Mariana Morais Teixeira ◽  
Jade Magalhães Alves da Silva ◽  
Letícia Oliveira Silva ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Low Income ◽  
Diabetic Foot ◽  
Short Form ◽  
Type I ◽  
Life Questionnaire ◽  
Cross Sectional ◽  
Resistance Profile ◽  
Systemic Involvement ◽  
Foot Disease

It is necessary to know the resistance profile of Staphylococcus aureus to better control diabetic foot ulcer infections, to establish rational antibiotic therapy, and to avoid the development of resistant strains. This cross-sectional study evaluated the clinical parameters, virulence, and antimicrobial resistance profiles of S aureus in patients with diabetic foot disease admitted to a public hospital. S aureus strains were identified in patients with diabetes with amputation indication. Infected tissue samples were collected, microbes were isolated and identified. The microbial resistance profile was determined. Samples were also analyzed for biofilm formation and other virulence markers. The 34 individuals examined were mostly men, black, aged 60 years on average, and generally had a low income and education level. Most individuals had type 2 diabetes, and the mean time since diagnosis was 13.9 years. On an SF-36 (the Medical Outcomes Study 36-item short-form health survey) quality-of-life questionnaire, 75% of individuals obtained a score equal to 0 for physical impairment. S aureus specimens from 17 patients were isolated, corresponding to 50% of samples. Five isolates were classified as methicillin-resistant S aureus (MRSA). Molecular typing revealed that 20% of MRSA strains were SCC mec type V and 80% were type I. All isolates were sensitive to doxycycline; 61.5% were resistant to erythromycin, 38.5% to cefoxitin, 30.7% to clindamycin and ciprofloxacin, 23% to meropenem, 15.3% to gentamicin, 38.5% to oxacillin, and 7.7% (one strain) to vancomycin. Regarding biofilm production, 53% of samples were able to produce biofilms, and 84.6% had icaA and/or icaD genes . Additionally, the following enterotoxin genes were identified in the isolates: seb, sec, seg, and sei (5.9%, 5.9%, 11.8%, and 23.9%, respectively) and agr types 1 (5.9%) and 2 (11.8%). Genotypic evaluation made it possible to understand the pathogenicity of S aureus strains isolated from the diabetic foot; laboratory tests can assist in the monitoring of patients with systemic involvement.

scholarly journals Short screening for diabetic foot disease in an omani population at Al-Dahira, Sultanate of Oman: A cross-sectional study

2021 ◽  
Vol 9 (1) ◽  
pp. 16
Author(s):  
SabriaA L Marshoudi ◽  
Fatma Ahmed ◽  
SyedWali Peeran ◽  
Amru AlBurji ◽  
Khalid Al-Kalbani ◽  
...  
Keyword(s):  
Diabetic Foot ◽  
Cross Sectional Study ◽  
Sultanate Of Oman ◽  
Sectional Study ◽  
Cross Sectional ◽  
Diabetic Foot Disease ◽  
Foot Disease

Omentin-1 and diabetic foot

2022 ◽  
pp. 153473462110698
Author(s):  
Tsvetan Gatev ◽  
Viktoriya Byalkova ◽  
Ivan Poromanski ◽  
Tsvetelina Velikova ◽  
Dobrin Vassilev ◽  
...  
Keyword(s):  
Diabetic Foot ◽  
Metabolic Disorders ◽  
Bioelectrical Impedance ◽  
Cross Sectional Study ◽  
Limited Data ◽  
Elisa Method ◽  
Cross Sectional ◽  
Diabetic Foot Disease ◽  
Foot Disease

Introduction: Diabetic foot disease is an advanced complication of diabetes mellitus, which is associated with severe invalidization and high mortality rate among affected people. Many factors are involved in its pathogenesis but not all of them are fully elucidated. Objectives: Adipose tissue and its hormones – adipokines, are related to diabetic complications and metabolic disorders. Until now, there are limited data on their role in diabetic foot. The aim of this cross-sectional study is to determine the levels of the adipokine omentin-1 in people with and without diabetic foot disease and to look for its potential involvement in this complication. Methods: Eighty patients with type 2 diabetes and mean age of 60.8±10.5 years were included in this study. They were divided into two groups: with (n=36) and without (n=44) diabetic foot disease. Standard antrometric, clinical and laboratory tests were made. Body composition was analyzed by bioelectrical impedance based device. Serum omentin-1 was measured using ELISA method. Results: Levels of omentin-1 were significantly higher among people with diabetic foot disease (700.2±345.1 ng/ml), compared to the other group (560.2±176.7 ng/ml). This difference remained significant even after adjusting for potential confounders. In a regression model omentin-1 proved its predictive value for development of diabetic foot. Conclusion: Adipokines, and particularly omentin-1, might be included in the pathogenesis of diabetic foot disease.

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