scholarly journals Correlation of sarcopenia and depressive mood in older community dwellers: a cross-sectional observational study in China

BMJ Open ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. e038089
Author(s):  
Lei Chen ◽  
Yunlu Sheng ◽  
Hanmei Qi ◽  
Tingting Tang ◽  
Jing Yu ◽  
...  

ObjectiveWhether sarcopenia is detrimental to depression is still controversial, which may be due to the three components of the sarcopenia. Our objective was to define the correlation between depression and sarcopenia in older Chinese community dwellers.DesignThe study has a cross-sectional design.SettingThe study was conducted in Jiangsu, China.ParticipantsA total of 101 men and 149 women aged 60 years or older were recruited.Outcome measuresLean tissue mass was measured by dual-energy X-ray absorptiometry. Muscle strength in the upper and lower limbs was measured by a handheld dynamometer and a chair stand test, respectively. Physical performance was assessed by gait speed and standing balance tests. Depressive mood was assessed using the Geriatric Depression Scale-30 (range 0–30).ResultsParticipants in the sarcopenia group had a higher mean depression score than the normal group (p=0.002). Pearson’s correlation analysis showed that depression was negatively associated with muscle strength (handgrip strength: R=−0.170, p=0.028 for women, R=−0.196, p=0.048 for men; chair stand test performance: R=0.252, p=0.002 for women, R=0.311, p=0.001 for men) and physical performance (gait speed: R=−0.200, p=0.009, standing balance test performance: R=−0.224, p=0.006, Short Physical Performance Battery (SPPB): R=−0.218, p=0.007 for women; SPPB: R=−0.252, p=0.01 for men). Multiple linear regression models revealed that depressive mood was inversely associated with chair stand test (β=0.325, p<0.001), gait speed (β=−0.009, p=0.041) and standing balance test (β=−0.24, p=0.016) after adjusting for confounding factors, while no significant correlation was observed between depressive mood and muscle mass.ConclusionThe diagnostic components of sarcopenia—strength of the leg muscles (chair stand test) and physical performance (gait speed and standing balance test)—were associated with depressive mood.

2019 ◽  
Vol 48 (Supplement_4) ◽  
pp. iv28-iv33
Author(s):  
Heewon Jung ◽  
Jae-Young Lim ◽  
Jihong Park

Abstract Background Short physical performance battery (SPPB) is a well-accepted clinical test to assess vulnerability in older adults. We aimed to develop and validate a multi-sensor based kiosk (e-SPPB kiosk) which can perform automated measurement for SPPB. Methods The e-SPPB kiosk was developed to measure 3 components of SPPB of standing balance, gait speed, and chair stand test with embedded sensors and algorithms. Feasibility and reliability of the e-SPPB kiosk was assessed with the manually measured SPPB (m-SPPB) by a physical therapist in participants aged 65 or older recruited from the outpatient rehabilitation clinic of the Seoul National University Bundang Hospital, Seongnam, Korea, from November 2018 to April 2019. Results In 34 participants with mean age of 73.6 (standard deviation [SD] 5.4), mean of e-SPPB total score was 10.1 (SD 2.2) and mean of m-SPPB total score was 10.2 (SD 2.3). Concordance between e-SPPB and m-SPPB total score was 0.94 (P&lt;0.001) and agreement by Kappa was 0.65 (P&lt;0.001). Agreements for components of e-SPPB and m-SPPB were 0.68 (P&lt;0.001), 0.73 (P&lt;0.001), 0.92 (P&lt;0.001) for standing balance, gait speed and chair stand test, respectively. Conclusion In older adults, physical performance measured by the e-SPPB kiosk correlated to m-SPPB measured by a single physical therapist. In multicenter studies for older people with physical performance as an outcome or selection criterion, e-SPPB kiosk can be used to reduce possible inter-rater variabilities of SPPB.


2021 ◽  
Vol 11 (8) ◽  
pp. 61-66
Author(s):  
Shagun S. Kamble ◽  
Gaurav C. Mhaske

Background - Falls are one of the measure concerns in geriatric population resulting in unintentional coming to rest on the ground. Majority of falls are multifactorial which commonly results in morbidity and mortality in rare cases. The aim of our study was to estimate the prevalence of high risk of falls in elderly in old age homes. Method -An observational study involving 140 participants in old age homes of Aurangabad, Maharashtra, India were selected by convenient sampling and prevalence was assessed by using TUG test, 30 second chair stand test, 4-stage balance test. Result – prevalence of high fall risk which impacted the physical capabilities and quality of life of elderly were 52.85%, 47.85%,55.71% according to TUG test, 30 second chair stand test, and 4 stage balance Test. Conclusion – Falls are major concern among elderly living in old age homes of Aurangabad. Our findings may assist the geriatric healthcare system to take early measures for elderly to prevent falls and spread awareness. Key words: Prevalence, Risk of fall, elderly, old age homes, TUG, 30 sec chair stand test, 4 stage balance Test, Aurangabad.


2019 ◽  
Vol 26 (11) ◽  
pp. 1-12 ◽  
Author(s):  
Carine Lumi ◽  
Fabrício Edler Macagnan ◽  
Adriana Kessler ◽  
Priscila De Toni ◽  
Adriana Maisonnave Raffone

Background/Aims The negative impact caused by haematopoietic stem cell transplantation still requires further investigation. This study aims to investigate the effects of this procedure on skeletal muscle strength, functional performance and fatigue sensation in the hospitalisation phase. Methods This prospective cohort study aimed to assess physical performance by measuring ventilatory muscle strength, peripheral muscle strength and fatigue in patients who underwent haematopoietic stem cell transplantation. Results The sample consisted of 30 patients of both sexes (63% men) with a mean age of 48.6 ± 13.2 years. Maximal inspiratory pressure and expiratory pressure decreased by 19% and 16%, respectively (P<0.001). There was a 16% reduction in handgrip strength in the second assessment (P<0.001), as well as a reduction of 30.6% in the 30-Second Chair Stand Test (P<0.001). The fatigue test score increased exponentially (60%) (P<0.001). Individuals with worse results in the 30-Second Chair Stand Test remained hospitalised for a longer period than those with better results (P=0.024). Conclusions This study concluded that after the transplantation of haematopoietic stem cells there was a relevant reduction in the results of the applied tests, as well as an increase in fatigue.


2018 ◽  
pp. 1-6
Author(s):  
S.M.L.M. Looijaard ◽  
S.J. Oudbier ◽  
E.M. Reijnierse ◽  
G.J. Blauw ◽  
C.G.M. Meskers ◽  
...  

Background: Sarcopenia is highly prevalent in the older population and is associated with several adverse health outcomes. Equipment to measure muscle mass and muscle strength to diagnose sarcopenia is often unavailable in clinical practice due to the related expenses while an easy physical performance measure to identify individuals who could potentially have sarcopenia is lacking. Objectives: This study aimed to assess the association between physical performance measures and definitions of sarcopenia in a clinically relevant population of geriatric outpatients. Design, setting and participants: A cross-sectional study was conducted, consisting of 140 community-dwelling older adults that were referred to a geriatric outpatient clinic. No exclusion criteria were applied. Measurements: Physical performance measures included balance tests (side-by-side, semi-tandem and tandem test with eyes open and -closed), four-meter walk test, timed up and go test, chair stand test, handgrip strength and two subjective questions on mobility. Direct segmental multi-frequency bioelectrical impedance analysis was used to measure muscle mass. Five commonly used definitions of sarcopenia were applied. Diagnostic accuracy was determined by sensitivity, specificity and area under the curve.Results: Physical performance measures, i.e. side-by-side test, tandem test, chair stand test and handgrip strength, were associated with at least one definition of sarcopenia. Diagnostic accuracy of these physical performance measures was poor. Conclusions: Single physical performance measures could not identify older individuals with sarcopenia, according to five different definitions of sarcopenia.


Healthcare ◽  
2021 ◽  
Vol 9 (9) ◽  
pp. 1205
Author(s):  
Alexandre D. Martins ◽  
João Paulo Brito ◽  
Rafael Oliveira ◽  
Tiago Costa ◽  
Fátima Ramalho ◽  
...  

Background: Breast cancer is the most common malignancy among women worldwide. The treatments may also cause neuromuscular and skeletal disorders; therefore, the aim of this study was to verify the existence of a relationship between heart rate variability and different functional fitness parameters in women survivors of breast cancer. Methods: This cross-sectional study included 25 women survivors of breast cancer, with a mean ± SD age, height, and body mass of 50.8 ± 8.8 years, 1.6 ± 0.7 m, and 67.1 ± 12.3 kg, respectively. Patients underwent measurements of heart rate variability with time and frequency domain analyses, as well as a “30 s chair-stand test”, “6 min walking test”, “timed up and go test”, and “ball throwing test”. Results: A multiple linear regression analysis showed that from the heart rate variability frequency domain, high frequency explained 21% (R2 = 0.21) of the “30 s chair-stand test” performance. Conclusion: The findings of this study highlight high frequency as a predictor of “30 s chair-stand test” performance, regardless of age and time after diagnosis, suggesting its usefulness as a clinical indicator of functionality in breast cancer survivors. This study presents a straightforward and non-invasive methodology predicting functional fitness in women breast cancer survivors potentially applicable to clinical practice.


2019 ◽  
Vol 27 (5) ◽  
pp. 663-669 ◽  
Author(s):  
Cody L. Sipe ◽  
Kevin D. Ramey ◽  
Phil P. Plisky ◽  
James D. Taylor

Testing balance and fall risk with older adults of varying abilities is of increasing importance. The primary aim of this study was to evaluate the validity of the lower quarter Y-balance test (YBT-LQ) in older adults. A secondary aim was to provide estimates of reliability with this population. A total of 30 male (n = 15) and female (n = 15) subjects (66.8 ± 6.5 years) performed the YBT-LQ, 30-s chair stand test, 8-foot up and go test, timed up and go test, single-leg stance, and Activities-Specific Balance Confidence Scale questionnaire. The YBT-LQ was performed on two separate occasions by two investigators in random order. YBT-LQ was significantly correlated with age (p < .01), timed up and go test (p = .003), 8-foot up and go test (p < .001), 30-s chair stand test (p < .001), Activities-Specific Balance Confidence Scale (p = .002), and single-leg stance (p = .005) performance. The intraclass correlation coefficient(3,1) score for the reliability of the YBT-LQ was .95 (95% confidence interval [.89, .97]). The YBT-LQ appears to be a valid and reliable assessment to use with older adults.


2017 ◽  
Vol 5 (10) ◽  
pp. e166 ◽  
Author(s):  
Gautam Adusumilli ◽  
Solomon Eben Joseph ◽  
Michael A Samaan ◽  
Brooke Schultz ◽  
Tijana Popovic ◽  
...  

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Kenichi Kono ◽  
Yoshifumi Moriyama ◽  
Hiroki Yabe ◽  
Ayaka Hara ◽  
Takeki Ishida ◽  
...  

Abstract Background The first objective of this study was to determine the relationship between muscle strength or physical performance and mortality, and the second objective was to show the relationship of Geriatric Nutritional Risk Index (GNRI) to muscle strength and physical performance decline. Methods We examined handgrip, the 5-times chair stand test, and GNRI in 635 maintenance hemodialysis patients and followed up for 72 months. Predictors for all-cause death were examined using Kaplan-Meier analysis and Cox proportional analysis. The relationship between possible sarcopenia and nutritional disorder (GNRI) was constructed receiver operating characteristic (ROC) curve. We used the Youden index to determine the optimal cutoff points for GNRI. Results The multivariate Cox proportional hazard analysis revealed that the GNRI did not show any significance, although handgrip (HR 3.61, 95% CI 1.70–7.68, p < 0.001) and the 5-times chair stand test (HR 1.71 95% CI 1.01–2.90, p = 0.045) were significant predictors for mortality. On the evaluation of possible sarcopenia by handgrip strength, the area under curve (AUC) on ROC curve analysis were 0.68 (95% CI 0.64–0.72), and 5-chair stand, the AUC on ROC were 0.55 (95% CI 0.51–0.60). The cut-off value for the GNRI discriminating those at possible sarcopenia by handgrip strength based on the Youden index was 91.5. Conclusions Our study suggests that the handgrip strength test of the AWGS 2019 sarcopenia consensus was a simple and useful tool to predict mortality in chronic hemodialysis patients. Furthermore, GNRI assessment can be a useful tool for screening before assessing possible sarcopenia when it is difficult to perform SARC-F to all patients.


2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
Henrik Ekström ◽  
Sölve Elmståhl ◽  
Lena Sandin Wranker

Introduction/Aim of the Study. One way of investigating health trends at the population level is to study the physical performance and functional ability in different birth cohorts. The information obtained can be used to predict illness, disability, and future needs for care. However, contradictory findings have been reported when comparing the physical performance of older adult birth cohorts. The aim of this study was to investigate whether the birth cohort is associated with the level of physical performance in 81-year-old men and women born twelve years apart. Materials and Methods. Birth cohorts of both sexes drawn from the Swedish study “Good Aging in Skåne” for the years 1920–22 and 1932–34 were compared. Walking, the step test, the chair stand test, and the handgrip strength test were used as proxies for the physical performance. The results were adjusted for lifestyle habits and common chronic geriatric diseases. Results. Both men and women in the later-born cohort walked more quickly and completed the chair stand test faster, and women were also quicker in the step test. No significant differences were found in the grip test, in either the male or female cohorts. Discussion. Normative reference values for physical tests of subjects of different ages can be misleading unless cohort effects are considered. Furthermore, age-related trajectories can also be misinterpreted if cohort effects are neglected which, in the longer perspective, could affect health care planning. Conclusion. Birth cohort effects should be considered when comparing walking speed, number of steps, chair stands, and the step test, in men and women of older age.


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