scholarly journals NutriQuébec: a unique web-based prospective cohort study to monitor the population’s eating and other lifestyle behaviours in the province of Québec

BMJ Open ◽  
2020 ◽  
Vol 10 (10) ◽  
pp. e039889
Author(s):  
Annie Lapointe ◽  
Catherine Laramée ◽  
Ariane Belanger-Gravel ◽  
David L Buckeridge ◽  
Sophie Desroches ◽  
...  
Keyword(s):  
Cohort Study ◽  
Health Status ◽  
Social Inequalities ◽  
Temporal Trends ◽  
Influence Factors ◽  
Personal Characteristics ◽  
Population Level ◽  
Prevention Policy ◽  
Web Based ◽  
Lifestyle Behaviours

IntroductionThe epidemic of non-communicable diseases including cardiovascular diseases and type 2 diabetes is attributable in large part to unhealthy eating and physical inactivity. In the fall of 2016, the Québec government launched its first-ever Government Health Prevention Policy (Politique gouvernementale de prévention en santé (PGPS)) to influence factors that lead to improved health status and quality of life as well as reduced social inequalities in health in the population of Québec. NutriQuébec is a web-based prospective open cohort study whose primary aim is to provide essential data for the evaluation of the PGPS on the Québec population’s eating and other lifestyle behaviours over time.Methods and analysisOver a first phase of 3 years, NutriQuébec will enrol 20 000 adults living in the province of Québec in Canada through a multimedia campaign designed to reach different segments of the population, including subgroups with lower socioeconomic status. Participants will be invited to complete on a web platform nine core questionnaires on a yearly basis. Questionnaires will assess several dimensions related to lifestyle, including eating and physical activity behaviours, as well as a large number of personal characteristics and global health status. Temporal trends in eating and lifestyle behaviours will be analysed in relation to the implementation of the PGPS to provide essential data for its evaluation at a population level. Data analyses will use sociodemographic weights to adjust responses of participants to achieve, so far as is possible, representativeness of the adult Québec population.Ethics and disseminationUniversité Laval Research Ethics Board approved the NutriQuébec project. Data analysis, presentations in conferences and publication of manuscripts are scheduled to start in 2020.Trial registration numberNCT04140071.

Abstract 15: Temporal Trends of Drug Eluting Stent Use After Myocardial Infarction: Does More Selective Utilization Impact Health Status Outcomes?

2011 ◽  
Vol 4 (suppl_1) ◽  
Author(s):  
Joshua M Stolker ◽  
Harshal Patil ◽  
Adnan K Chhatriwalla ◽  
Lakshmi Venkitachalam ◽  
Kevin F Kennedy ◽  
...  
Keyword(s):  
Health Status ◽  
Temporal Trends ◽  
Population Level ◽  
Drug Eluting Stent ◽  
Complete Health ◽  
Angina Frequency ◽  
Acute Mi ◽  
Drug Eluting ◽  
The Mean ◽  
Selection Of

BACKGROUND Despite widespread acceptance of drug eluting stents (DES), concerns about cost and safety contributed to lower DES use by late 2006, particularly in off-label scenarios such as acute MI. The population-level impact of this trend on health status is unknown. METHODS We evaluated Seattle Angina Questionnaire (SAQ) scores among patients (pts) undergoing in-hospital PCI in TRIUMPH, a 24-center registry of acute MI. For each 3-month period of enrollment, we calculated the frequency of DES use and the mean 6-month Angina Frequency (SAQ-AF) score for pts treated that quarter. We then constructed a linear regression model to evaluate whether DES use, or time periods of high vs. low DES use, were independently associated with 6-month SAQ-AF scores. RESULTS Among 1744 MI pts undergoing PCI with complete health status assessments, 1033 were treated with DES (59%). DES use decreased significantly in late 2006, but overall 6-month angina burden remained stable ( Figure ). After adjusting for multiple clinical factors, SAQ-AF scores exhibited a borderline association with DES use (ß-coefficient 1.86 ± 1.0, p=0.06). When dichotomizing pts into years with high (2005-06) and low (2007-08) DES use, there was no relationship between high vs. low DES use on SAQ-AF in the multivariable model (ß=0.01 ± 1.0, p=0.99). CONCLUSION More selective use of DES after 2006 has not impacted population-level angina control at 6 months among MI pts treated with PCI. This suggests that clinicians were able to reduce DES use through better selection of those pts most likely to benefit from DES therapy, but further research is needed to better understand the processes of care associated with these findings.

scholarly journals Characteristics and health status of patients with and without confirmed HFpEF

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
C Deaton ◽  
F Forsyth ◽  
J Mant ◽  
D Edwards ◽  
R Hobbs ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Primary Care ◽  
Cohort Study ◽  
Health Status ◽  
Functional Impairment ◽  
Funding Source ◽  
Walk Distance ◽  
Minute Walk Distance ◽  
Minute Walk

Abstract Aims Patients with heart failure with preserved ejection fraction (HFpEF) are usually older and multi-morbid and diagnosis can be challenging. The aims of this cohort study were to confirm diagnosis of HFpEF in patients with possible HFpEF recruited from primary care, to compare characteristics and health status between those with and without HFpEF, and to determine factors associated with health status in patients with HFpEF. Methods Patients with presumed HFpEF were recruited from primary care practices and underwent clinical assessment and diagnostic evaluation as part of a longitudinal cohort study. Health status was measured by Montreal Cognitive Assessment (MOCA), 6-minute walk test, symptoms, and the Kansas City Cardiomyopathy Questionnaire (KCCQ), and quality of life (QoL) by EQ-5D-5L visual analogue scale (VAS). Results 151 patients (mean age 78.5±8.6 years, 40% women, mean EF 56% + 9.4) were recruited and 93 (61.6%) were confirmed HFpEF (those without HFpEF had other HF and cardiac diagnoses). Patients with and without HFpEF did not differ by age, MOCA, blood pressure, heart rate, NYHA class, proportion with atrial fibrillation, Charlson Comorbidity Index, or NT-ProBNP levels. Patients with HFpEF were more likely to be women, overweight or obese, frail, and to be more functionally impaired by 6 minute walk distance and gait speed than those without. Although not statistically significant, patients with HFpEF had clinically significant differences (>5 points) on the physical limitations, symptom burden and clinical summary subscales of the KCCQ, but did not differ by other subscales or by EQ-5D-5L VAS (70±17 vs 73±19, p=0.385). More patients with HFpEF reported daytime dyspnoea (63% vs 46%, p=0.035) and fatigue (81% vs 61%, p=0.008), but not other symptoms compared to those without HFpEF. For both groups BMI was moderately negatively correlated with KCCQ subscale scores, and 6 minute walk distance was positively correlated with KCCQ subscales. Conclusions Nearly 40% were not confirmed as HFpEF indicating the challenges of diagnosis. Patients with confirmed HFpEF differed by sex, overweight/obesity, frailty, functional impairment, and symptoms but not by age or comorbidities from those without HFpEF. These differences were reflected in some subscale scores of the KCCQ, but not how patients reported their quality of life on the KCCQ QoL subscale and EQ-5D-5L VAS. Older patients with HFpEF reported relatively high QoL despite poor health status by functional impairment, frailty and symptoms. Funding Acknowledgement Type of funding source: Public grant(s) – National budget only. Main funding source(s): National Institute of Health Research School of Primary Care Research

Social inequalities in the associations between urban green spaces, self-perceived health and mortality in Brussels: Results from a census-based cohort study

2021 ◽  
Vol 70 ◽  
pp. 102603
Author(s):  
Lucía Rodriguez-Loureiro ◽  
Lidia Casas ◽  
Mariska Bauwelinck ◽  
Wouter Lefebvre ◽  
Charlotte Vanpoucke ◽  
...  
Keyword(s):  
Cohort Study ◽  
Social Inequalities ◽  
Perceived Health ◽  
Green Spaces ◽  
Urban Green ◽  
Urban Green Spaces ◽  
Health And Mortality

scholarly journals Prospective association between adherence to the Mediterranean diet and hepatic steatosis: the Swiss CoLaus cohort study

BMJ Open ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. e040959
Author(s):  
Saman Khalatbari-Soltani ◽  
Pedro Marques-Vidal ◽  
Fumiaki Imamura ◽  
Nita G. Forouhi
Keyword(s):  
Cohort Study ◽  
Fatty Liver ◽  
Hepatic Steatosis ◽  
Mediterranean Diet ◽  
Population Level ◽  
Inverse Association ◽  
Alcoholic Fatty Liver ◽  
The Mediterranean ◽  
Prospective Association

ObjectiveThe Mediterranean diet has been promoted as a healthy dietary pattern, but whether the Mediterranean diet may help to prevent hepatic steatosis is not clear. This study aimed to evaluate the prospective association between adherence to the Mediterranean diet and risk of hepatic steatosis.DesignPopulation-based prospective cohort study.SettingThe Swiss CoLaus Study.ParticipantsWe evaluated 2288 adults (65.4% women, aged 55.8±10.0 years) without hepatic steatosis at first follow-up in 2009–2012. Adherence to the Mediterranean diet was scaled as the Mediterranean diet score (MDS) based on the Mediterranean diet pyramid ascertained with responses to Food Frequency Questionnaires.Outcome measuresNew onset of hepatic steatosis was ascertained by two indices separately: the Fatty Liver Index (FLI, ≥60 points) and the non-alcoholic fatty liver disease (NAFLD) score (≥−0.640 points). Prospective associations between adherence to the Mediterranean diet and risk of hepatic steatosis were quantified using Poisson regression.ResultsDuring a mean 5.3 years of follow-up, hepatic steatosis was ascertained in 153 (6.7%) participants by FLI criteria and in 208 (9.1%) by NAFLD score. After multivariable adjustment, higher adherence to MDS was associated with lower risk of hepatic steatosis based on FLI: risk ratio 0.84 (95% CI 0.73 to 0.96) per 1 SD of MDS; 0.85 (0.73 to 0.99) adjusted for BMI; and 0.85 (0.71 to 1.02) adjusted for both BMI and waist circumference. When using NAFLD score, no significant association was found between MDS and risk of hepatic steatosis (0.95 (0.83 to 1.09)).ConclusionA potential role of the Mediterranean diet in the prevention of hepatic steatosis is suggested by the inverse association observed between adherence to the Mediterranean diet and incidence of hepatic steatosis based on the FLI. The inconsistency of this association when hepatic steatosis was assessed by NAFLD score points to the need for accurate population-level assessment of fatty liver and its physiological markers.

Temporal Trends in Undervaccination: A Population-Based Cohort Study

2021 ◽  
Author(s):  
Matthew F. Daley ◽  
Liza M. Reifler ◽  
Jo Ann Shoup ◽  
Komal J. Narwaney ◽  
Elyse O. Kharbanda ◽  
...  
Keyword(s):  
Cohort Study ◽  
Temporal Trends ◽  
Population Based

scholarly journals Temporal trends in severe COVID-19 outcomes in patients with rheumatic disease: a cohort study

2020 ◽  
Author(s):  
April Jorge ◽  
Kristin M D'Silva ◽  
Andrew Cohen ◽  
Zachary S Wallace ◽  
Natalie McCormick ◽  
...  
Keyword(s):  
Cohort Study ◽  
Rheumatic Disease ◽  
Temporal Trends

A population-based analysis in 375,233 cases of heart failure stages A, B and C. Real world epidemiology of prevalence and temporal trends in South-European populations

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
S Jimenez ◽  
M Cainzos-Achirica ◽  
D Monterde ◽  
L Garcia-Eroles ◽  
C Enjuanes ◽  
...  
Keyword(s):  
Heart Failure ◽  
Chronic Conditions ◽  
Temporal Trends ◽  
Population Level ◽  
Population Based ◽  
Relative Increase ◽  
Funding Source ◽  
Private Company ◽  
Healthcare Database ◽  
Evolutionary Changes

Abstract Background Prevalence of congestive heart failure (CHF) and predisposing conditions has described previously. Most of these studies evaluated centre-European or north-American populations. However, the prevalence and evolutionary changes of Heart Failure stages A, B and C has not been fully elucidated in Mediterranean cohorts. Purpose To estimate the prevalence of CHF (HF Stage C) and four additional key chronic cardiovascular, metabolic and renal conditions predisposing to the development of CHF (HF Stages A and B) at a population level in a south-European healthcare area. We analysed the evolutionary changes in the prevalence in these five conditions. Methods In a healthcare area of 1,3Millions inhabitants, we extracted health related information of all individuals ≥55 years old. We analysed data of 375,233 individuals included in the population-based healthcare database of a public Institute of Health between 2015 and 2017. The conditions of interest were CHF, chronic kidney disease (CKD), diabetes mellitus (DM), ischemic heart disease (IHD) and hypertension (HTN). Results The prevalence of chronic conditions was high, particularly of HTN (48.2–48.9%) and DM individuals (14.6–14.8%). The other conditions were less frequent, with prevalence around 2–4% for IHD, 5–9% for CKD and 2–4% for CHF (Table). However, the less frequent conditions had a striking upward trend with over 1,500 new prevalent cases per year between 2015 and 2017 for CHF (45% relative increase), more than 2,500 new prevalent cases for IHD (67% relative increase) and more than 4,000 new prevalent cases per year for CKD (44% relative increase). Conclusion In this south European cohort, there were a high prevalence of HTN and DM as risk factors and a significant trend of increasing prevalence in high cost chronic conditions such as CHF, IHD and CKD. Funding Acknowledgement Type of funding source: Private company. Main funding source(s): The present study was funded by an unrestricted research grant from Vifor Pharma.

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