Women’s well-being and functioning after evidence-based antenatal care: a protocol for a systematic review of intervention studies

IntroductionThe 2016 WHO antenatal guidelines propose evidence-based recommendations to improve maternal outcomes. We aim to complement these recommendations by describing and estimating the effects of the interventions recommended by WHO on maternal well-being or functioning.Methods and analysisWe will conduct a systematic review of experimental and quasi-experimental studies evaluating women’s well-being or functioning following the implementation of evidence-based antenatal interventions, published in peer-reviewed journals through a 15-year interval (2005–2020). The lead reviewer will screen all records identified at MEDLINE, EMBASE, CINAHL Plus, LILACS and SciELO. Two other reviewers will control screening strategy quality. Quality and risk of bias will be assessed using a specially designed instrument. Data synthesis will consider the instruments applied, how often they were used, conditions/interventions for positive or negative effects documented, statistical measures used to document effectiveness and how results were presented. A random-effects meta-analysis comparing frequently used instruments may be conducted.Ethics and disseminationThe study will be a systematic review with no human beings’ involvement, therefore not requiring ethical approval. Findings will be disseminated through peer-reviewed publication and scientific events.PROSPERO registration numberCRD42019143436.

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The Effectiveness of Digital Interventions for Psychological Well-Being in the Workplace: A Systematic Review Protocol

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph17010255 ◽

2019 ◽

Vol 17 (1) ◽

pp. 255 ◽

Cited By ~ 1

Author(s):

Maria Armaou ◽

Stathis Konstantinidis ◽

Holly Blake

Keyword(s):

Systematic Review ◽

Meta Analysis ◽

Experimental Studies ◽

Well Being ◽

Psychological Well Being ◽

Scientific Databases ◽

Digital Interventions ◽

Quasi Experimental ◽

Review Protocol ◽

Mental Well Being

Objective: Psychological well-being has been associated with desirable individual and organisational outcomes. This systematic review aims to assess the effectiveness of digital interventions for the improvement of psychological well-being and/or the prevention/management of poor mental well-being in the workplace. Methods: This review protocol is registered in PROSPERO (CRD42019142428). Scientific databases including MEDLINE, Web of Science, CINAHL, PsycINFO, Cochrane Register of Controlled Trials (CENTRAL) and EMBASE will be searched for relevant studies published between January 1990 and July 2019. Studies will be included if they report specific primary and secondary outcomes of digital interventions delivered to adults in the workplace for the improvement of their psychological wellbeing and/or the prevention/management of poor mental well-being and were published in English. Following screening of titles and abstracts, full texts of potentially eligible papers will be screened in duplicate to identify studies that assess the effectiveness of those digital interventions. Discrepancies will be resolved through consensus or by consulting a third reviewer. An integrated narrative synthesis will assess included studies’ findings, and a meta-analysis will be performed if included studies appear to be homogeneous. The “Cochrane Collaboration’s Risk of Bias” tool and the JBI (Joanna Briggs Institute) Critical Appraisal Checklist for Quasi-Experimental Studies will be used to appraise included studies. Conclusion: The results of this work will provide recommendations on the use of digital interventions for the promotion of psychological well-being at work. It will also guide the development of future workplace digital interventions and subsequent primary research in this field.

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Effectiveness of Nutritional Education for Obese Older Adults With Frailty: A Systematic Review and Meta-Analysis

Innovation in Aging ◽

10.1093/geroni/igaa057.1291 ◽

2020 ◽

Vol 4 (Supplement_1) ◽

pp. 401-401

Author(s):

Yue-Heng Yin ◽

Liu Yat Justina

Keyword(s):

Systematic Review ◽

Physical Function ◽

Meta Analysis ◽

Experimental Studies ◽

Well Being ◽

Risk Of Bias ◽

Cochrane Library ◽

Nutritional Education ◽

Hand Search ◽

Education Interventions

Abstract Obesity has been shown to intensify the decline of physical function and lead to frailty. Nutrition is an important method in managing obesity and frailty, while seldom reviews have ever explored the effects of nutritional education interventions. We conducted a systematic review (PROSPERO: CRD42019142403) to explore the effectiveness of nutritional education interventions in managing body composition and physio-psychosocial parameters related to frailty. Randomized controlled trials and quasi-experimental studies were searched in CINAHL, Cochrane Library, EMBASE, MEDLINE, PsycINFO, PubMed and Scopus from 2001 to 2019. Hand search for the reference lists of included papers was conducted as well. We assessed the quality of included studies by Cochrane risk of bias tool. Meta-analyses and narrative synthesis were used to analyse the data. Two studies with low risk of bias were screened from 180 articles, which involved 177 older people with an average age of 69.69±4.08 years old. The results showed that nutritional education was significantly effective in reducing body weight and fat mass than exercises, and it was beneficial to enhancing physical function and psychosocial well-being. But the effects of nutritional education in increasing muscle strength were not better than exercises. The combined effects of nutritional education and exercises were superior than either exercises or nutritional education interventions solely in preventing the loss of lean mass and bone marrow density, and in improving physical function. Due to limited numbers of relevant studies, the strong evidence of effectiveness of nutritional education interventions on reversing frailty is still lacking.

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The effectiveness of hope-fostering interventions in palliative care: A systematic review and meta-analysis

Palliative Medicine ◽

10.1177/0269216321994728 ◽

2021 ◽

pp. 026921632199472

Author(s):

Natalia Salamanca-Balen ◽

Thomas V Merluzzi ◽

Man Chen

Keyword(s):

Quality Of Life ◽

Systematic Review ◽

Palliative Care ◽

Meta Analysis ◽

Symptom Burden ◽

Well Being ◽

Medium Effect ◽

Spiritual Well Being ◽

Quasi Experimental

Background: The concept of hope is an important theme in chronic illness and palliative care and has been associated with increased psycho-spiritual well-being and quality of life. Psycho-spiritual interventions have been described in this population, but no systematic review of hope-enhancing interventions or hopelessness-reducing interventions has been conducted for persons with palliative care diseases. Aim: To describe and assess the effectiveness of interventions in palliative care that measure hope and/or hopelessness as an outcome. Design: This systematic review and meta-analysis was pre-registered (Prospero ID: CRD42019119956). Data sources: Electronic databases, journals, and references were searched. We used the Cochrane criteria to assess the risk of bias within studies. Results: Thirty-five studies (24 randomized controlled trials, 5 quasi-experimental, 6 pre-post studies) involving a total of 3296 palliative care patients were included. Compared with usual/standard cancer care alone, interventions significantly increased hope levels at a medium effect size ( g = 0.61, 95% confidence interval (CI) = 0.28–0.93) but did not significantly reduce hopelessness ( g = −0.08, 95% CI = −0.18 to 0.02). It was found that interventions significantly increase spirituality ( g = 0.70, 95% CI = 0.02–1.37) and decrease depression ( g = −0.29, 95% CI = −0.51 to −0.07), but had no significant effect over anxiety, quality of life, and symptom burden. Overall, quality of evidence across the included studies was rated as low. Conclusions: Evidence suggests that interventions can be effective in increasing hope in palliative care patients.

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The State of Interventions for Sibling Conflict and Aggression: A Systematic Review

Trauma Violence & Abuse ◽

10.1177/1524838015622438 ◽

2015 ◽

Vol 18 (4) ◽

pp. 396-406 ◽

Cited By ~ 14

Author(s):

Corinna Jenkins Tucker ◽

David Finkelhor

Keyword(s):

Systematic Review ◽

Social Skills ◽

Meta Analysis ◽

Well Being ◽

Sibling Relationship ◽

Control Group ◽

Sibling Conflict ◽

Negative Effects ◽

Online Databases ◽

Children's Social Skills

Sibling conflict and aggression is often a pervasive part of family life that parents want help managing and can have negative effects on children’s well-being. The purpose of this systematic review is to evaluate current research regarding programs to reduce sibling conflict and aggression and promote positive sibling relationships. Online databases, reference lists, and Google Scholar were searched using key words and inclusion/exclusion criteria were applied. The search located five unique studies of programs focused on school-aged children. Heterogeneity of the studies precluded meta-analysis, but characteristics of the studies were systematically described. Three interventions were aimed at directly improving children’s social skills and two interventions trained parents on mediation techniques to use during sibling conflicts. Overall, of the four studies that included assessment of children’s social skills, the results were positive. Two of the three studies that evaluated sibling relationship quality demonstrated improved sibling interactions compared with the control group. With further research and evidentiary support, these programs have promise to modify sibling behaviors as part of current parenting education programs or as a stand-alone program to address sibling conflict and aggression.

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Effectiveness of Marital Couple Interventions on Marital Conflict: a Systematic Review and Meta-analysis of Experimental Studies

10.21203/rs.3.rs-207900/v1 ◽

2021 ◽

Author(s):

Likawunt Samuel Samuel ◽

Getu Degu Alene

Keyword(s):

Systematic Review ◽

Marital Conflict ◽

Couple Therapy ◽

Marital Therapy ◽

Meta Analysis ◽

Intervention Group ◽

Experimental Studies ◽

Married Couples ◽

Well Being ◽

Risk Of Bias

Abstract Background: Marital life is an important social institution that greatly influences the health and well-being of individuals and the entire society. Inherently, marriage is a complex phenomenon that the risks for marital instability are ubiquitous including social upheavals, stay home order due to Coronavirus Disease 2019 (COVID 19). Several studies have been proposed different interventions to optimize the quality of marital life. However, problems related to marital conflict are getting worse and there are uncertainties about the effectiveness of the interventions. Thus, the current systematic review was aimed at examining the effectiveness of interventions in reducing a variety of aspects of marital conflict among the cohort of married couples.Methods: Randomized controlled trial (RCT) and Qazi experimental studies describing the effectiveness of marital couple interventions published over the last 10 years were retrieved from six electronic databases using different search terms, Medical subject heading (MeSH) terms “Marital therapy”, “Couple therapy”, or “Marital couple therapy” included in this study. The risk of bias in individual studies assessed based on the Cochrane Risk of Bias Tool. The effectiveness of the interventions was examined by comparing the intervention group with those who did not receive the intervention. Results: A total of 14, 536 records are searched from 6 databases, and eleven of these studies are included in the final systematic review and meta-analysis. Overall, the included studies were identified to have a low risk of bias and a substantial level of heterogeneity (I2 =96%). The meta-analysis confirmed that marital couple’s interventions significantly improved marital conflict among distressed couples (Pooled effect size, -1.71, [-2.93, -0.49])Conclusions: This finding indicated that marital couples’ interventions effectively reduce marital conflict among a cohort of married couples. Thus, marital counselors and educators are strongly suggested to compile and use the interventions outline in this study. Funding: There is no source of funding, that, the authors have no competing interests to declare. Systematic review registration: This study is registered as PROSPERO: CRD42020218280

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Testosterone Administration Alters Hepatic Blood Flow Across Age: Systematic Review of Animal Experimental Studies

Journal of Morphological Sciences ◽

10.1055/s-0038-1669470 ◽

2018 ◽

Vol 35 (02) ◽

pp. 096-101

Author(s):

Ricardo Nucci ◽

Valéria Tanasov ◽

Walter Krause Neto ◽

Romeu de Souza ◽

Eliane Gama

Keyword(s):

Systematic Review ◽

Molecular Mechanisms ◽

Meta Analysis ◽

Experimental Studies ◽

Hepatic Metabolism ◽

Negative Effects ◽

Hepatic Congestion ◽

Testosterone Administration ◽

And Function ◽

Hepatic Injuries

AbstractTestosterone levels decline gradually with advancing age. At this point, testosterone administration as a therapy has been largely used to improve different outcomes. However, testosterone induces dose-dependent negative effects on the structure and function of the liver across age. Therefore, the present study aimed to carry out a systematic review of the effects of testosterone administration on the hepatic structure of adult and aged animals. We have searched the PubMed, Google Scholar, Science Direct, Scielo and Lilacs databases for animal experimental studies on the effects of testosterone administration on the hepatic structure across age. After applying the inclusion and exclusion criteria, we included two articles in a systematic review and meta-analysis (regarding adult/aged rats). We have shown through a systematic review with meta-analysis that testosterone may cause chronic hepatic congestion. However, the present review had a small number of studies, which was considered a limitation. At this point, we encourage the development of more studies to elucidate the cellular and molecular mechanisms involved in hepatic injuries, as well as the hepatic metabolism of exogenous testosterone across age.

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Impact of improved cookstoves on women’s and child health in low and middle income countries: a systematic review and meta-analysis

Thorax ◽

10.1136/thoraxjnl-2017-210952 ◽

2018 ◽

Vol 73 (11) ◽

pp. 1026-1040 ◽

Cited By ~ 17

Author(s):

Megha Thakur ◽

Paulien A W Nuyts ◽

Esther A Boudewijns ◽

Javier Flores Kim ◽

Timor Faber ◽

...

Keyword(s):

Systematic Review ◽

Preterm Birth ◽

Child Health ◽

Meta Analysis ◽

Experimental Studies ◽

Middle Income ◽

Middle Income Countries ◽

Quasi Experimental ◽

Women And Children ◽

Low And Middle Income

ObjectivesImproved biomass cookstoves may help reduce the substantial global burden of morbidity and mortality due to household air pollution (HAP) that disproportionately affects women and children in low and middle income countries (LMICs).DesignSystematic review and meta-analysis of (quasi-)experimental studies identified from 13 electronic databases (last update: 6 April 2018), reference and citation searches and via expert consultation.SettingLMICsParticipantsWomen and childrenInterventionsImproved biomass cookstovesMain outcome measuresLow birth weight (LBW), preterm birth, perinatal mortality, paediatric acute respiratory infections (ARIs) and COPD among women.ResultsWe identified 53 eligible studies, including 24 that met prespecified design criteria. Improved cookstoves had no demonstrable impact on paediatric lower ARIs (three studies; 11 560 children; incidence rate ratio (IRR)=1.02 (95% CI 0.84 to 1.24)), severe pneumonia (two studies; 11 061 children; IRR=0.88 (95% CI 0.39 to 2.01)), LBW (one study; 174 babies; OR=0.74 (95% CI 0.33 to 1.66)) or miscarriages, stillbirths and infant mortality (one study; 1176 babies; risk ratio (RR) change=15% (95% CI –13 to 43)). No (quasi-)experimental studies assessed preterm birth or COPD. In observational studies, improved cookstoves were associated with a significant reduction in COPD among women: two studies, 9757 participants; RR=0.74 (95% CI 0.61 to 0.90). Reductions in cough (four studies, 1779 participants; RR=0.72 (95% CI 0.60 to 0.87)), phlegm (four studies, 1779 participants; RR=0.65 (95% CI 0.52 to 0.80)), wheezing/breathing difficulty (four studies; 1779 participants; RR=0.41 (95% CI 0.29 to 0.59)) and conjunctivitis (three studies, 892 participants; RR=0.58 (95% CI 0.43 to 0.78)) were observed among women.ConclusionImproved cookstoves provide respiratory and ocular symptom reduction and may reduce COPD risk among women, but had no demonstrable child health impact.RegistrationPROSPERO: CRD42016033075

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Utilising Digital Health Technology to Support Patient-Healthcare Provider Communication in Fragility Fracture Recovery: Systematic Review and Meta-Analysis

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph16204047 ◽

2019 ◽

Vol 16 (20) ◽

pp. 4047 ◽

Cited By ~ 3

Author(s):

Lalit Yadav ◽

Ayantika Haldar ◽

Unyime Jasper ◽

Anita Taylor ◽

Renuka Visvanathan ◽

...

Keyword(s):

Systematic Review ◽

Fragility Fracture ◽

Digital Health ◽

Meta Analysis ◽

Population Sample ◽

Experimental Studies ◽

Fragility Fractures ◽

Medical Subject Headings ◽

Intention To Treat ◽

Quasi Experimental

The objective of this review is to evaluate the effectiveness of digital health supported targeted patient communication versus usual provision of health information, on the recovery of fragility fractures. The review considered studies including older people, aged 50 and above, with a fragility fracture. The primary outcome was prevention of secondary fractures by diagnosis and treatment of osteoporosis, and its adherence. This review considered both experimental and quasi-experimental study designs. A comprehensive search strategy was built to identify key terms including Medical subject headings (MeSH) and applied to the multiple electronic databases. An intention to treat analysis was applied to those studies included in the meta-analysis and odds ratio was calculated with random effects. Altogether, 15 studies were considered in the final stage for this systematic review. Out of these, 10 studies were Randomised controlled trials (RCT) and five were quasi experimental studies, published between the years 2003 and 2016 with a total of 5037 participants. Five Randomised control trails were included in the meta-analysis suggesting that digital health supported interventions were overall, twice as effective when compared with the usual standard care (OR 2.13, 95% CI 1.30–3.48), despite the population sample not being homogeneous. Findings from the remaining studies were narratively interpreted.

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Mindfulness-Based Interventions for Youth With Anxiety: A Systematic Review and Meta-Analysis

Research on Social Work Practice ◽

10.1177/1049731516684961 ◽

2017 ◽

Vol 29 (2) ◽

pp. 195-205 ◽

Cited By ~ 22

Author(s):

Debra S. Borquist-Conlon ◽

Brandy R. Maynard ◽

Kristen Esposito Brendel ◽

Anne S. J. Farina

Keyword(s):

Systematic Review ◽

Anxiety Disorder ◽

Confidence Interval ◽

Anxiety Disorders ◽

Meta Analysis ◽

Experimental Studies ◽

Risk Of Bias ◽

Quasi Experimental ◽

Disorder Risk

Purpose: To examine the effects on anxiety of mindfulness-based interventions (MBIs) among youth with anxiety disorders. Method: Systematic review and meta-analytic procedures were employed to synthesize experimental and quasi-experimental studies authored between 1980 and 2015. Results: The search yielded five studies from five countries reporting results for a total of 188 youth between the ages of 5 and 18 (mean age 13.26) who met criteria for an anxiety disorder. Risk of bias varied across studies. Meta-analytic results suggest a moderate and significant effect ( g = .62; 95% confidence interval = [0.20, 1.04], p = .004). Heterogeneity was moderate ( I2 = 47.22) and not statistically significant ( Q = 7.58, df = 4, p = .11), thus moderator analyses were not warranted. Discussion: The findings of this review suggest that MBIs for the treatment of anxiety in youth with anxiety disorders are effective.

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