CHANGES OF BLOOD PLASMA ELEMENT CONTENTS IN X-RAY IRRADIATED MICE BY PIXE ANALYSIS

1995 ◽  
Vol 05 (02n03) ◽  
pp. 85-95 ◽  
Author(s):  
ITSURO TAMANOI ◽  
AKEMI NAKAMURA ◽  
KIYOFUSA HOSHIKAWA ◽  
MUTSUMI KACHI ◽  
BUNSHIRO GOTO ◽  
...  
Keyword(s):  
Trace Elements ◽  
Blood Plasma ◽  
Whole Body ◽  
Pixe Analysis ◽  
X Ray ◽  
Dead Mouse ◽  
Small Rise ◽  
Quantitative Changes ◽  
Pixe Method ◽  
In Blood Plasma

The quantitative changes of elements in blood plasma were observed with the passage of time after X-ray whole body irradiation with 12 Gy on C57BL/6J mice by PIXE method. From 4 days after irradiation, dead mouse was found and all mice died by 8 days. Hematocrit (Ht) values indicated a decrease from the 1st day, but on days 3 and 4 there was a small rise. Finally the values became 64 % of that of non-irradiated control on day 7, it was just before death. By analysis with PIXE method, 15 elements were observable in blood plasma of control mice. The elements such as P, S, Cl, K, Ca and Cr were abundant and Fe and Br followed. As trace elements, the peaks of Zn, Cu and Ni were clearly observed. After irradiation, K and Ca decreased on day 1st, afterwards increased gradually. On the contrary, the elements, S, Cl, were rather stable. While Fe decreased from 1st day, Cu increased from the day 2. Zn and Ni showed intensely down and rise in amount, and decreased on day 7. The results of possible measurement of the changes in amount of these elements of blood plasma suggest PIXE method is an easy and useful way for diagnosis.

PIXE ANALYSIS OF TRACE ELEMENTS IN CLAM SHELLS MARKED WITH IRON RUSTING

1996 ◽  
Vol 06 (03n04) ◽  
pp. 517-522 ◽  
Author(s):  
YOSHINORI KOSHIKAWA ◽  
NOBUAKI ARAI ◽  
WATARU SAKAMOTO ◽  
KOJI YOSHIDA
Keyword(s):  
Trace Elements ◽  
Trace Element ◽  
Intensity Ratio ◽  
Ruditapes Philippinarum ◽  
Pixe Analysis ◽  
X Ray ◽  
Elemental Concentrations ◽  
Element Concentrations ◽  
Pixe Method

Trace element concentrations in short necked clam Ruditapes philippinarum marked shells with iron rusting were determined by particle induced X-ray emission (PIXE) method. Element such as Ca, Mn, Fe, Zn, Sr, and Br were detected in the shells. The Fe/Ca X-ray intensity ratio decreased exponentially on the day after marking. It was concluded that the higher Fe concentration on marked clams was caused by attached iron rusting. The concentrations of Fe, Br, and Sr differed among the 3 stations (Kamaya, Shigaki, and Iwatani), suggesting that elemental concentrations may be related to the growth of clams.

TRACE ELEMENT ANALYSIS IN ANTS COLLECTED IN JAPAN, FINLAND AND SWEDEN

1992 ◽  
Vol 02 (03) ◽  
pp. 405-411 ◽  
Author(s):  
K. KITAO
Keyword(s):  
Trace Elements ◽  
Trace Element ◽  
Trace Element Analysis ◽  
Reasonable Accuracy ◽  
Element Analysis ◽  
Pixe Analysis ◽  
X Ray ◽  
Minor Elements ◽  
Analytical Results ◽  
Pixe Method

Particle induced x-ray emission has been used to determine the concentration of trace elements in ants (Formicidae). Scanning PIXE analysis was also used to determine the distribution of these elements. Samples of ants were collected from gardens, buildings or from the roadway in Japan, Finland and Sweden. The only pre-treatments were dusting and washing. In each run of experiments we used only one individual ant and have obtained the analytical results of a reasonable accuracy. We have detected chemical minor elements, i.e., Mn, Fe, Cu, Zn, Rb, Br and Sr. The PIXE, and scanning PIXE method proved to be useful and sensitive enough to measure trace elements in such small insects as ants.

Trace Element Status (Zinc, Copper, Selenium, Iron, Manganese) in Patients with Long-Term Home Parenteral Nutrition

2016 ◽  
Vol 69 (2) ◽  
pp. 120-124 ◽  
Author(s):  
Milan Dastych Jr. ◽  
Michal Šenkyřík ◽  
Milan Dastych ◽  
František Novák ◽  
Petr Wohl ◽  
...  
Keyword(s):  
Trace Elements ◽  
Parenteral Nutrition ◽  
Blood Plasma ◽  
Whole Blood ◽  
Statistical Significance ◽  
Home Parenteral Nutrition ◽  
Control Group ◽  
The Status ◽  
In Blood Plasma

Background: The objective of the present study was to determine concentrations of zinc (Zn), copper (Cu), iron (Fe), selenium (Se) in blood plasma and manganese (Mn) in the whole blood in patients with long-term home parenteral nutrition (HPN) in comparison to the control group. Patients and Methods: We examined 68 patients (16 men and 52 women) aged from 28 to 68 years on a long-term HPN lasting from 4 to 96 months. The short bowel syndrome was an indication for HPN. The daily doses of Zn, Cu, Fe, Se and Mn in the last 3 months were determined. Results: No significant differences in blood plasma were found for Zn, Cu and Fe in patients with HPN and in the control group (p > 0.05). The concentration of Mn in whole blood was significantly increased in HPN patients (p < 0.0001), while Se concentration in these patients was significantly decreased (p < 0.005). The concentration of Mn in the whole blood of 16 patients with cholestasis was significantly increased compared to the patients without cholestasis (p < 0.001). The Cu concentration was increased with no statistical significance. Conclusion: In long-term HPN, the status of trace elements in the patients has to be continually monitored and the daily substitution doses of these elements have to be flexibly adjusted. Dosing schedule needs to be adjusted especially in cases of cholestatic hepatopathy. A discussion about the optimal daily dose of Mn in patients on HPN is appropriate. For clinical practice, the availability of a substitution mixture of trace elements lacking Mn would be advantageous.

DETERMINATION OF TRACE ELEMENTS IN HUMAN SALIVA BY PIXE TECHNIQUE

1996 ◽  
Vol 06 (01n02) ◽  
pp. 273-276 ◽  
Author(s):  
P. HATAMI ◽  
H. PEYROVAN ◽  
H. AFARIDEH ◽  
S. SHOJAEI
Keyword(s):  
Trace Elements ◽  
Healthy Volunteers ◽  
Trace Element ◽  
Element Concentration ◽  
Trace Element Concentration ◽  
Human Saliva ◽  
Normal Range ◽  
Pixe Analysis ◽  
X Ray

Mineral trace element concentration of human saliva from healthy volunteers, were investigated by Proton-Induced X-ray Emission (PIXE) analysis. The specimens were bombarded with Proton beams of 2 MeV from a Van de Graaff accelerator at NRC . The object of this measurement was to find a normal range of trace element concentration for Iranian people.

ELEMENTAL ANALYSIS OF MOUSE HAIR BY PIXE METHOD

1994 ◽  
Vol 04 (01) ◽  
pp. 19-28 ◽  
Author(s):  
ITSURO TAMANOI ◽  
KUNIO OOHASHI ◽  
SHINJI MATSUMOTO ◽  
ZENJI MURAKOSHI ◽  
TUNEYA MATSUMOTO
Keyword(s):  
Elemental Analysis ◽  
Mus Musculus ◽  
Strain Difference ◽  
Pixe Analysis ◽  
X Ray ◽  
Head Hair ◽  
Elemental Contents ◽  
Pixe Method

Constitutional elements of head hair of mouse (Mus musculus) were investigated by Particle-Induced X-ray Emission (PIXE) analysis. The high peaks of S, K and Ca, and the low peaks of several other elements were observed in PIXE spectra of all the specimens from the used strains. The result clearly indicates that the ratios of these elemental contents are different among the coat colors of mice. Further, we observed strain difference even in the same color.

scholarly journals On PIXE Analysis of Medical Samples: Thalassemia & Wilson

2017 ◽  
pp. 5105-5110
Author(s):  
Amir Pishkoo
Keyword(s):  
Wilson’S Disease ◽  
Wilson's Disease ◽  
Pixe Analysis ◽  
X Ray ◽  
Six Elements ◽  
Pixe Method

The contents of six elements (Cl, K, Ca, Fe, Cu, Zn) for medical samples of 30 patients (15 with wilson's disease and 15 with Thalassemia's disease) were determined by proton induced X-ray emission (PIXE) method. In analysis of these samples, abnormal contents of Cu for wilson's disease and of Fe for Thalassemia's disease were observed which shows that for these cases the situation of patient's illness is very serious.

Particle-Induced X-ray Emission (PIXE) Analysis of Minor and Trace Elements in Gallstones of Nigerian Patients

2009 ◽  
Vol 134 (1) ◽  
pp. 13-24 ◽  
Author(s):  
Olusegun I. Alatise ◽  
Eusebius I. Obiajunwa ◽  
Oladejo O. Lawal ◽  
Abdulrasheed R. K. Adesunkanmi
Keyword(s):  
Trace Elements ◽  
Pixe Analysis ◽  
Minor And Trace Elements ◽  
X Ray

Study of Trace Elements in Blood of Cancer Patients by Proton-Induced X-Ray Emission (PIXE) Analysis

1994 ◽  
pp. 351-355
Author(s):  
M. A. Durosinmi ◽  
J. O. Ojo ◽  
A. F. Oluwole ◽  
O. A. Akanle ◽  
N. M. Spyrou
Keyword(s):  
Trace Elements ◽  
Cancer Patients ◽  
Pixe Analysis ◽  
X Ray

PIXE STUDIES ON POTASSIUM AND CALCIUM IN MOUSE BLOOD PLASMA AFTER TRANSPLANTATION OF EL-4 TUMOR CELLS

1995 ◽  
Vol 05 (04) ◽  
pp. 255-264 ◽  
Author(s):  
ITSURO TAMANOI ◽  
AKEMI NAKAMURA ◽  
KIYOFUSA HOSHIKAWA ◽  
MUTSUMI KACHI ◽  
KUNIO OOHASHI ◽  
...  
Keyword(s):  
Blood Plasma ◽  
Tumor Cells ◽  
Time Course ◽  
The Other ◽  
Histocompatibility Antigens ◽  
Mouse Blood ◽  
Major Histocompatibility Antigens ◽  
The Difference ◽  
Quantitative Changes ◽  
Pixe Method

The quantitative changes in the elements, amounts of Cl, K, Ca, in blood plasma were measured by PIXE method. The samples were obtained at appropriate intervals after transplantation of EL-4 tumor cells in three strains of mice, C57BL/6J (H-2b), C57BL/10J (abbreviation: B10; H-2b) and A/J (H-2a). Transplanted EL-4 tumor cells proliferated in both strains of C57BL/6J and B10. In A/J mice, transplanted EL-4 cells proliferated about 10 days and then were rejected completely by the immunological reaction according to the difference of major histocompatibility antigens. The amounts of Cl in plasma remained at similar level in the time course in any strains, but K fluctuated in C57BL/6J and B10, and less in A/J. On the other hand, Ca showed always higher values in C57BL/6J than other two strains of mice. In B10 mice, Ca increased just before death, but in A/J it decreased at the time of healing by rejection. These changes of Ca in the three strains of mice were related quantitatively 10 the hematocrit values of these strains of mice after transplantation of EL-4 cells.

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