Texture Analysis and Genetic Algorithms for Osteoporosis Diagnosis
Early diagnosis of osteoporosis can efficiently predict fracture risk. There is a great demand to prevent this disease. The goal of this study was to distinguish osteoporotic cases from healthy controls on 2D bone radiograph images, using texture analysis and genetic algorithms (GAs). Gray Level Co-occurrence Matrix (GLCM), Run length Matrix (RLM) and Binarized Statistical Image Features (BSIF) were used for texture analysis. Features are numerous and parameter-dependent. The related experts can pick out the useful input features for the classifier. It however remains a difficult task and may be inefficient or even harmful as the data pattern is not clear. In this paper, GAs were used to optimize the two parameters of the co-occurrence matrix (distance parameter or pixel separation, orientation or direction) and the number of gray levels used in the preprocessing quantification step. GAs were also used to select the best combination of features extracted from GLCM and RLM matrices. Experiments were conducted on two populations composed of Osteoporotic Patients and Control Subjects. Results show that GAs combined with GLCM and BSIF features can improve the classification rates (ACC = 87.50%) obtained using GLCM (ACC = 77.8%) alone.