AN ANALYTICAL FRAMEWORK FOR MODELING EVOKED AND EVENT-RELATED POTENTIALS

2004 ◽  
Vol 14 (02) ◽  
pp. 653-666 ◽  
Author(s):  
AXEL HUTT
Keyword(s):  
Auditory Evoked Potentials ◽  
Event Related Potentials ◽  
Analytical Framework ◽  
Multidimensional Data ◽  
Dimensional System ◽  
Segmentation Method ◽  
Neuronal Dynamics ◽  
Related Potentials ◽  
Low Dimensional ◽  
Number Of Segments

The present work reviews briefly a segmentation method and a modeling approach for multivariate quasi-stationary data. The combination of both parts allows the extraction of low-dimensional models from multidimensional data. The segmentation method is applied to event-related potentials and fields and early auditory evoked potentials and extracts ERP- and ERF-components and early auditory waves objectively and independent from the number of segments. Additionally, the early auditory wave Pa is modeled by a two-dimensional system of ordinary differential equations. We find a common topology of wave Pa, which lets us conjecture intrinsic low-dimensional underlying attractors in the corresponding neuronal dynamics.

Low-dimensional versus high-dimensional chaos in brain function – is it an and/or issue?

2001 ◽  
Vol 24 (5) ◽  
pp. 823-824 ◽  
Author(s):  
Márk Molnár
Keyword(s):  
Brain Function ◽  
Sensory Information ◽  
Event Related Potentials ◽  
Cognitive Effort ◽  
Neural Systems ◽  
Sensory Information Processing ◽  
Related Potentials ◽  
Dimensional Complexity ◽  
Low Dimensional ◽  
The Brain

We discuss whether low-dimensional chaos and even nonlinear processes can be traced in the electrical activity of the brain. Experimental data show that the dimensional complexity of the EEG decreases during event-related potentials associated with cognitive effort. This probably represents increased nonlinear cooperation between different neural systems during sensory information processing.

scholarly journals Effects of intensity, attention and medication on auditory-evoked potentials in patients with fibromyalgia

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
N. Samartin-Veiga ◽  
A. J. González-Villar ◽  
Y. Triñanes ◽  
C. Gómez-Perretta ◽  
M. T. Carrillo-de-la-Peña
Keyword(s):  
Auditory Processing ◽  
Auditory Evoked Potentials ◽  
Event Related Potentials ◽  
Pathophysiological Mechanism ◽  
Auditory Event ◽  
Significant Relationships ◽  
Sensory Modalities ◽  
Related Potentials ◽  
Auditory Event Related Potentials

AbstractFibromyalgia (FM) has been associated to an increased processing of somatosensory stimuli, but its generalization to other sensory modalities is under discussion. To clarify this, we studied auditory event-related potentials (AEPs) to stimuli of different intensity in patients with FM and healthy controls (HCs), considering the effects of attention mechanisms and medication. We performed two experiments: In study 1 (n = 50 FM, 60 HCs), the stimuli were presented randomly within the sequence; in study 2 (n = 28 FM, 30 HCs), they were presented in blocks of the same intensity. We analyzed intensity and group effects on N1-P2 amplitude and, only for the FM group, the effect of medication and the correlation between AEPs and clinical variables. Contrary to the expectation, the patients showed a trend of reduced AEPs to the loudest tones (study 1) or no significant differences with the HCs (study 2). Medication with central effects significantly reduced AEPs, while no significant relationships between the N1-P2 amplitude/intensity function and patients’ symptoms were observed. The findings do not provide evidence of augmented auditory processing in FM. Nevertheless, given the observed effect of medication, the role of sensory amplification as an underlying pathophysiological mechanism in fibromyalgia cannot be discarded.

Evoked Potentials

2016 ◽  
Author(s):  
Marc R. Nuwer
Keyword(s):  
Evoked Potentials ◽  
Auditory Evoked Potentials ◽  
Motor Evoked Potentials ◽  
Clinical Care ◽  
Event Related Potentials ◽  
Clinical Tests ◽  
Therapeutic Trials ◽  
Complementary Role ◽  
Related Potentials ◽  
Vestibular Evoked Potentials

Visual evoked potentials, brainstem auditory evoked potentials, and somatosensory evoked potentials are established clinical tests that are useful for the diagnosis of multiple sclerosis. Motor evoked potentials, cognitive event-related potentials, and vestibular evoked potentials also are used clinically to test additional pathways and functions. These objective, reproducible tools can identify clinically silent lesions, predict clinical deterioration risk, and localize levels of impairment. They differ from magnetic resonance imaging in that they assess function rather than anatomy and thereby fill a complementary role in clinical care. They also are useful in therapeutic trials because they can predict outcomes in parallel with, or earlier than, clinical examinations.

Auditory evoked potentials in young patients with Down syndrome. Event-related potentials (P3) and histaminergic system

1997 ◽  
Vol 5 (4) ◽  
pp. 301-309 ◽  
Author(s):  
Rainer Seidl ◽  
Erwin Hauser ◽  
Günther Bernert ◽  
Manfred Marx ◽  
Michael Freilinger ◽  
...  
Keyword(s):  
Down Syndrome ◽  
Evoked Potentials ◽  
Auditory Evoked Potentials ◽  
Young Patients ◽  
Event Related Potentials ◽  
Histaminergic System ◽  
Related Potentials

scholarly journals Head Injury Exposure in Veterans Presenting to Memory Disorders Clinic: An Observational Study of Clinical Characteristics and Relationship of Event-Related Potentials and Imaging Markers

2021 ◽  
Vol 12 ◽  
Author(s):  
Katherine W. Turk ◽  
Anna Marin ◽  
Kylie A. Schiloski ◽  
Ana L. Vives-Rodriguez ◽  
Prayerna Uppal ◽  
...  
Keyword(s):  
Head Injury ◽  
Auditory Evoked Potentials ◽  
Event Related Potentials ◽  
Event Related Potential ◽  
Self Report ◽  
Memory Disorders ◽  
Amyloid Pet ◽  
Injury Group ◽  
Related Potentials ◽  
Imaging Markers

Objective: Traumatic brain injury (TBI) and repetitive head impacts (RHI) related to blasts or contact sports are commonly reported among military service members. However, the clinical implications of remote TBI and RHI in veterans remains a challenge when evaluating older veterans at risk of neurodegenerative conditions including Alzheimer's disease (AD) and Chronic Traumatic Encephalopathy (CTE). This study aimed to test the hypothesis that veterans in a memory disorders clinic with remote head injury would be more likely to have neurodegenerative clinical diagnoses, increased rates of amyloid PET positivity, higher prevalence of cavum septum pellucidi/vergae, and alterations in event-related potential (ERP) middle latency auditory evoked potentials (MLAEPs) and long latency ERP responses compared to those without head injuries.Methods: Older veterans aged 50–100 were recruited from a memory disorders clinic at VA Boston Healthcare system with a history of head injury (n = 72) and without head injury history (n = 52). Patients were classified as reporting prior head injury including TBI and/or RHI exposure based on self-report and chart review. Participants underwent MRI to determine presence/absence of cavum and an ERP auditory oddball protocol.Results: The head injury group was equally likely to have a positive amyloid PET compared to the non-head injury group. Additionally, the head injury group were less likely to have a diagnosis of a neurodegenerative condition than those without head injury. P200 target amplitude and MLAEP amplitudes for standard and target tones were decreased in the head injury group compared to the non-head injury group while P3b amplitude did not differ.Conclusions: Veterans with reported remote head injury evaluated in a memory disorders clinic were not more likely to have a neurodegenerative diagnosis or imaging markers of neurodegeneration than those without head injury. Decreased P200 target and MLAEP target and standard tone amplitudes in the head injury group may be relevant as potential diagnostic markers of remote head injury.

scholarly journals Revealing the Physiological Origin of Event-Related Potentials using Electrocorticography in Humans

2021 ◽  
Author(s):  
Hohyun Cho ◽  
Gerwin Schalk ◽  
Markus Adamek ◽  
Ladan Moheimanian ◽  
William G. Coon ◽  
...  
Keyword(s):  
Evoked Potentials ◽  
Auditory Evoked Potentials ◽  
Event Related Potentials ◽  
Oscillatory Activity ◽  
Phase Reset ◽  
Phase Resetting ◽  
Clinical Value ◽  
Related Potentials

AbstractThe scientific and clinical value of event-related potentials (ERPs) depends on understanding the contributions to them of three possible mechanisms: (1) additivity of time-locked voltage changes; (2) phase resetting of ongoing oscillations; (3) asymmetrical oscillatory activity. Their relative contributions are currently uncertain. This study uses analysis of human electrocorticographic activity to quantify the origins of movement-related potentials (MRPs) and auditory evoked potentials (AEPs). The results show that MRPs are generated primarily by endogenous additivity (88%). In contrast, P1 and N1 components of AEPs are generated almost entirely by exogenous phase reset (93%). Oscillatory asymmetry contributes very little. By clarifying ERP mechanisms, these results enable creation of ERP models; and they enhance the value of ERPs for understanding the genesis of normal and abnormal auditory or sensorimotor behaviors.

On the value of P300 Event-Related Potentials in the Differential Diagnosis of Dementia

1984 ◽  
Vol 145 (6) ◽  
pp. 652-656 ◽  
Author(s):  
J. P. J. Slaets ◽  
C. Fortgens
Keyword(s):  
Differential Diagnosis ◽  
Elderly Patients ◽  
Auditory Evoked Potentials ◽  
Event Related Potentials ◽  
P300 Latency ◽  
Age Related ◽  
Significant Difference ◽  
Diagnosis Of Dementia ◽  
Related Potentials ◽  
Differential Diagnosis Of Dementia

SummaryThe possible value of event-related potentials (ERPs) in the differential diagnosis of dementia was investigated in a group of 42 demented elderly patients, 29 non-demented elderly patients, and 10 healthy young controls. The auditory evoked potentials were elicited by using target and non-target auditory stimuli. There was no significant difference in N100 and P200 latency between these groups. Our results indicate an age-related increase of P300 latency of 0.3 msec/year in the non-demented subjects. There was no significant difference in P300 latency between demented and non-demented patients, and the latencies vary widely within the groups of elderly patients.

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