LABEL-FREE DETECTION OF Pb2+ USING SPECIFIC DNAZYME AND UNMODIFIED Au NANOPARTICLE PROBE

2018 ◽  
Vol 25 (03) ◽  
pp. 1850073
Author(s):  
CHENGYONG LI ◽  
ZIKE ZHAO ◽  
YAOQIAN LIU ◽  
LULU LV ◽  
BING QI ◽  
...  
Keyword(s):  
Food Safety ◽  
Detection Limit ◽  
Environmental Monitoring ◽  
Rapid Detection ◽  
Au Nanoparticles ◽  
Color Variation ◽  
Au Nanoparticle ◽  
Measurement Tool ◽  
Label Free ◽  
Label Free Detection

A simple and sensitive Pb[Formula: see text] sensor is developed based on label-free 17E DNAzyme and unmodified Au nanoparticles. On this basis, Pb[Formula: see text] concentration can be judged according to the color variation of Au nanoparticles. The detection limit is 100[Formula: see text]nM and linear range is 100[Formula: see text]nM–16[Formula: see text][Formula: see text]M. It can serve as a measurement tool for Pb[Formula: see text] rapid detection, which provides reference for the development of sensors in environmental monitoring and food safety.

scholarly journals Paper-based fluorogenic RNA aptamer sensors for label-free detection of small molecules

2020 ◽  
Vol 12 (21) ◽  
pp. 2674-2681
Author(s):  
Fatemeh Shafiei ◽  
Kathleen McAuliffe ◽  
Yousef Bagheri ◽  
Zhining Sun ◽  
Qikun Yu ◽  
...  
Keyword(s):  
Small Molecules ◽  
Rapid Detection ◽  
Rna Aptamer ◽  
Label Free ◽  
Target Analytes ◽  
Label Free Detection

A paper-based portable fluorogenic RNA sensor for the selective, sensitive, and rapid detection of target analytes.

A nanofluidic device for ultrasensitive and label-free detection of tetracycline in association with γ-cyclodextrin and GO

2021 ◽  
Vol 13 (15) ◽  
pp. 1832-1838
Author(s):  
Jiaxi Cheng ◽  
Fenghua Jiang ◽  
Siqi Zhang
Keyword(s):  
Detection Limit ◽  
Water Samples ◽  
Recovery Rate ◽  
Label Free ◽  
Detection Range ◽  
Low Detection Limit ◽  
Sensing Platform ◽  
Label Free Detection ◽  
Nanofluidic Device

We develop a label-free, sensitive and selective nanochannel sensing platform for detection of TC. The nanosensor provided a low detection limit, a wide detection range and excellent recovery rate in different water samples.

scholarly journals A gold nanopopcorn attached single-walled carbon nanotube hybrid for rapid detection and killing of bacteria

2014 ◽  
Vol 2 (43) ◽  
pp. 7534-7543 ◽  
Author(s):  
Thomas J. Ondera ◽  
Ashton T. Hamme II
Keyword(s):  
Carbon Nanotube ◽  
Rapid Detection ◽  
Label Free ◽  
Hybrid Nanomaterials ◽  
Single Walled Carbon Nanotube ◽  
Single Walled Carbon ◽  
Label Free Detection ◽  
Selective Label

Antibody conjugated gold nanopopcorn attached SWCNT hybrid nanomaterials possess great potential for selective label-free detection and photothermal killing of bacteria.

scholarly journals New Ultrasensitive Sandwich-Type Immunoassay of Dendritic Tri-Fan Blade-like PdAuCu Nanoparticles/Amine-Functionalized Graphene Oxide for Label-Free Detection of Carcinoembryonic Antigen

Micromachines ◽  
2021 ◽  
Vol 12 (10) ◽  
pp. 1256
Author(s):  
Pingping Xu ◽  
Wenpo Feng ◽  
Mei Wang ◽  
Ling Zhang ◽  
Gaofeng Liang ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Carcinoembryonic Antigen ◽  
Au Nanoparticle ◽  
Functionalized Graphene ◽  
Label Free ◽  
Functionalized Graphene Oxide ◽  
Amine Functionalized ◽  
Label Free Detection ◽  
Sandwich Type ◽  
Fan Blade

The early detection of tumor markers has an effective role in the treatment of cancer. Here, a new sandwich-type electrochemical immunosensor for early label-free detection of the cancer biomarker carcinoembryonic antigen (CEA) was developed. Dendritic tri-fan blade-like PdAuCu nanoparticles (PdAuCu NPs)/amine functionalized graphene oxide (NH2-GO) were the label of secondary antibodies (Ab2), and Au nanoparticle-decorated polydopamines (Au/PDA) were immobilized on a screen-printed carbon electrode (SPCE) as the substrate materials. Dendritic tri-fan blade-like PdAuCu NPs/NH2-GO was synthesized according to a simple hydrothermal procedure and used to immobilize antibodies (Ab2) with large surfaces areas, increased catalytic properties and good adsorption to amplify the current signals. Subsequently, Ab2/PdAuCu NPs/NH2-GO catalyzed the reduction of H2O2 in the sandwich-type immunoreactions. Under optimal conditions, the immunosensor exhibited a satisfactory response to CEA with a limit detection of 0.07 pg mL−1 and a linear detection range from 0.1 pg mL−1 to 200 ng mL−1. The proposed immunosensor could be suitable enough for a real sample analysis of CEA, and has clinical value in the early diagnosis of cancer.

Label-free fluorescence assay for rapid detection of RNase H activity based on Tb3+-induced G-quadruplex conjugates

2017 ◽  
Vol 9 (20) ◽  
pp. 3055-3060 ◽  
Author(s):  
Kefeng Wu ◽  
Changbei Ma ◽  
Haisheng Liu ◽  
Hailun He ◽  
Weimin Zeng ◽  
...  
Keyword(s):  
Rapid Detection ◽  
Rnase H ◽  
Fluorescence Assay ◽  
Label Free ◽  
Label Free Detection ◽  
G Quadruplex

A simple fluorescence based biosensor for label-free detection of RNase H activity based on Tb3+-induced G-quadruplex conjugates is reported.

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