MULTICENTRIC RETROPERITONEAL LEIOMYOSARCOMA WITH SATELLITE LESIONS NOT FOUND ON PET-CT: A CASE REPORT AND LITERATURE REVIEW

2014 ◽  
Vol 17 (03) ◽  
pp. 1472004
Author(s):  
Chin-Chiang Hsieh ◽  
Rong-Sen Yang ◽  
Yih-Jyh Lin ◽  
Kuo-Yuan Huang
Keyword(s):  
Clinical Presentation ◽  
Left Kidney ◽  
Resonance Imaging ◽  
Iliac Arteries ◽  
Large Size ◽  
Bony Destruction ◽  
Positron Emission ◽  
Pet Ct ◽  
Magnetic Resonance Imaging Mri ◽  
Operative Findings

Most retroperitoneal leiomyosarcomas are clinically silent and are usually detected late, so a large size main tumor accompanied by satellite lesions might be presented. We report a case of a large multicentric retroperitoneal leiomyosarcoma with satellite lesions in the left iliac region, mimicking an abscess, was found on pre-operative pelvic computed tomography (CT). Positron emission tomography (PET-CT) was performed, but revealed only focal bony destruction of the left ilium and no discernable lesions in the abdomen. After resection of the iliacus satellite lesion, CT and magnetic resonance imaging (MRI) of the abdomen revealed another huge retroperitoneal leiomyosarcoma with invasion of the left kidney and ureter, descending colon and left iliac arteries. The patient was then treated with a multidisciplinary extensive excision operation. The clinical presentation, operative findings and imaging findings were reported and related articles were reviewed.

scholarly journals Localization of Insulinoma Using 68Ga-DOTATATE PET/CT Scan

2016 ◽  
Vol 102 (1) ◽  
pp. 195-199 ◽  
Author(s):  
Pavel Nockel ◽  
Bruna Babic ◽  
Corina Millo ◽  
Peter Herscovitch ◽  
Dhaval Patel ◽  
...  
Keyword(s):  
Intraoperative Ultrasound ◽  
Imaging Study ◽  
Imaging Studies ◽  
Minimally Invasive Surgical ◽  
Positron Emission ◽  
Pet Ct ◽  
Manual Palpation ◽  
Invasive Surgical Approach ◽  
Magnetic Resonance Imaging Mri ◽  
Operative Findings

Abstract Context: Reliable localization of insulinoma is critical for successful treatment. Objective: This study compared the accuracy of 68Gallium DOTA-(Tyr3)-octreotate (Ga-DOTATATE) positron emission tomography (PET)/computed tomography (CT) to anatomic imaging modalities, selective arterial secretagogue injection (SASI), and intraoperative ultrasound (IO ultrasound) and palpation for localizing insulinoma in patients who were biochemically cured. Design, Setting, and Patients: We conducted a retrospective analysis of 31 patients who had an insulinoma. The results of CT, magnetic resonance imaging (MRI), ultrasound, IO ultrasound, 68Ga-DOTATATE PET/CT, SASI, and operative findings were analyzed. Intervention, Main Outcome Measures, and Results: The insulinomas were correctly localized in 17 out of 31 (55%) patients by CT, in 17 out of 28 (61%) by MRI, in 6 out of 28 (21%) by ultrasound, and in 9 out of 10 (90%) by 68Ga-DOTATATE. In 29 of 31 patients (93.5%) who had IO ultrasound, an insulinoma was successfully localized. Thirty patients underwent SASI, and the insulinoma was regionalized in 28 out of 30 patients (93%). In 19 out of 23 patients (83%), manual palpation identified insulinoma. In patients who had all 4 noninvasive imaging studies, CT was concordant with 68Ga-DOTATATE in 6 out of 9 patients (67%), MRI in 8 out of 9 (78%), ultrasound in 0 out of 9; the lesion was only seen by 68Ga-DOTATATE in 1 out of 9 (11%). Conclusions 68Ga-DOTATATE PET/CT identifies most insulinomas and may be considered as an adjunct imaging study when all imaging studies are negative and when a minimally invasive surgical approach is planned.

scholarly journals Possibilities of small-size glioblastoma visualization by PET-CT with 11C-choline (experimental study)

2021 ◽  
Vol 11 (4) ◽  
pp. 30-36
Author(s):  
N. A. Kostenikov ◽  
V. F. Dubrovskaya ◽  
E. G. Kovan'ko ◽  
O. Yu. Mirolyubova ◽  
Yu. R. Ilyushchenko ◽  
...  
Keyword(s):  
Brain Tumors ◽  
Treatment Effectiveness ◽  
Minimum Size ◽  
Resonance Imaging ◽  
Malignant Brain Tumors ◽  
Glioma C6 ◽  
Positron Emission ◽  
Pet Ct ◽  
Magnetic Resonance Imaging Mri ◽  
Intracerebral Tumor

Introduction. The minimum size of malignant brain tumors detected by positron emission and computed tomography (PET-CT) exceeds 6-7 mm. One of the ways to increase the sensitivity of PET-CT in detecting of malignant brain tumors is to increase the administered activity of the radiopharmaceutical 11C-choline.Purpose & tasks. The aim of the study was to experimentally study the possibility of obtaining a small-size glioblastoma (GB) images (up to 4 mm) by PET-CT with the 11C-choline.Materials and methods. The study was performed on 24 rats with implanted intracerebral tumor «Glioma C6» (glioblastoma). Animals underwent magnetic resonance imaging (MRI) with contrast enhancement (CE) and PET-CT with 11C-choline for 21 days after tumor transplantation.Results. It was shown that using two methods: MRI with CE and PET-CT with 11C-choline, a glioblastoma up to 4 mm can be convincingly visualized.Conclusion. The data obtained can be crucial for early detection of glioblastoma, justification of treatment tactics, evaluation of the treatment effectiveness and prediction the outcome of the disease.

scholarly journals MRI and PET-CT Failed to Differentiate Between Hepatic Malignancy and Brucelloma

2018 ◽  
Vol 5 (4) ◽  
Author(s):  
Peter W Schreiber ◽  
Adrian Schmid ◽  
Stefania Fagagnini ◽  
Arne Kröger ◽  
Bart Vrugt ◽  
...  
Keyword(s):  
Clinical Presentation ◽  
Positron Emission Tomography Imaging ◽  
Resonance Imaging ◽  
Hepatic Malignancy ◽  
Local Complication ◽  
Tomography Imaging ◽  
Positron Emission ◽  
Resected Liver ◽  
Pet Ct ◽  
Polymerase Chain

Abstract Brucellosis is a common, worldwide zoonosis. Clinical presentation is protean and often goes unrecognized. Hepatic brucelloma is a rare local complication of chronic brucellosis. We report a case in which magnetic resonance imaging and positron emission tomography imaging prompted suspicion of a hepatic malignancy. Diagnosis was ultimately made by serology and polymerase chain reaction of resected liver tissue.

scholarly journals Adapting Imaging Protocols for PET-CT and PET-MRI for Immunotherapy Monitoring

Cancers ◽  
2021 ◽  
Vol 13 (23) ◽  
pp. 6019
Author(s):  
Bettina Beuthien-Baumann ◽  
Christos Sachpekidis ◽  
Regula Gnirs ◽  
Oliver Sedlaczek
Keyword(s):  
Hybrid Imaging ◽  
Resonance Imaging ◽  
Mri Scan ◽  
Imaging Protocols ◽  
Diagnostic Potential ◽  
Positron Emission ◽  
Pet Ct ◽  
Tissue Contrast ◽  
Magnetic Resonance Imaging Mri ◽  
Clinical Scanner

Hybrid imaging with positron emission tomography (PET) in combination with computer tomography (CT) is a well-established diagnostic tool in oncological staging and restaging. The combination of PET with magnetic resonance imaging (MRI) as a clinical scanner was introduced approximately 10 years ago. Although MRI provides superb soft tissue contrast and functional information without the radiation exposure of CT, PET-MRI is not as widely introduced in oncologic imaging as PET-CT. One reason for this hesitancy lies in the relatively long acquisition times for a PET-MRI scan, if the full diagnostic potential of MRI is exploited. In this review, we discuss the possible advantages of combined imaging protocols of PET-CT and PET-MRI, within the context of staging and restaging of patients under immunotherapy, in order to achieve “multi-hybrid imaging” in one single patient visit.

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