Research News

2002 ◽  
Vol 06 (13) ◽  
pp. 476-485
Keyword(s):  
Rheumatoid Arthritis ◽  
Multiple Sclerosis ◽  
Esophageal Cancer ◽  
Laparoscopic Cholecystectomy ◽  
Cancer Risk ◽  
Neural Mechanisms ◽  
Fish Sauce ◽  
Rotavirus Vaccine ◽  
Human Trial ◽  
Cot Death

University of Melbourne Offers Hope for Diabetic Blindness. Gene Silencing Technology Unveiled. Multiple Sclerosis and Rheumatoid Arthritis Drug Ready for Human Testing. Vaccinating against CMV. Chinese Fish Sauce May Increase Esophageal Cancer Risk. India to Help in Safer Rotavirus Vaccine. Bio-fertiliser Bacteria Developed. Biodegradable Plastic for Computer Housing. Researchers Find Neural Mechanisms of Motivation and Reward. Scientist Hopes to Recreate LUCA Gene. Probiotics Study in Combating Eczema. Sensitive DNA Technique for Solving Old Crime Cases. Study on Link between Cot-death and Teen Fatalities. Singapore Researcher Ups IVF Success Rate. Robotic System Investigated for Laparoscopic Cholecystectomy. Method against Diabetes-related Blindness Ready for Human Trial.

Research and development round-up: November 2007

2007 ◽  
Vol 5 (11) ◽  
pp. 512-515
Author(s):  
Nicola O'Connell
Keyword(s):  
Breast Cancer ◽  
Rheumatoid Arthritis ◽  
Multiple Sclerosis ◽  
Heart Failure ◽  
Premature Infants ◽  
Haemorrhagic Stroke ◽  
Pressure Control ◽  
Rotavirus Vaccine ◽  
Treatment And Prevention ◽  
Reduce Risk

In brief Combination therapy plus antibiotics for multiple sclerosis Rheumatoid arthritis patients achieve clinical remission with tocilizumab Cholesterol-lowering drugs and haemorrhagic stroke ACEIs and ARBs provide equal blood pressure control NSAIDs may reduce risk of Parkinson's disease Tezosentan does not appear to improve outcomes for acute heart failure Rotavirus vaccine demonstrates efficacy in premature infants Oseltamivir effective for treatment and prevention of influenza in children Common treatments for sinus infections may not be effective Marijuana compound shows promise in fighting breast cancer

Cell-based Tolerogenic Therapy, Experience from Animal Models of Multiple Sclerosis, Type 1 Diabetes and Rheumatoid Arthritis

2017 ◽  
Vol 23 (18) ◽  
Author(s):  
Ivana Stojanovic ◽  
Mirjana Dimitrijevic ◽  
Marta Vives-Pi ◽  
Maria Jose Mansilla ◽  
Irma Pujol-Autonell ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Multiple Sclerosis ◽  
Type 1 Diabetes ◽  
Animal Models

scholarly journals Solar Radiation and Vitamin D: Mitigating Environmental Factors in Autoimmune Disease

2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
Gerry K. Schwalfenberg
Keyword(s):  
Rheumatoid Arthritis ◽  
Multiple Sclerosis ◽  
Inflammatory Bowel Disease ◽  
Vitamin D ◽  
Type 1 Diabetes ◽  
Autoimmune Disease ◽  
Solar Radiation ◽  
Inflammatory Bowel

This paper looks at the environmental role of vitamin D and solar radiation as risk reduction factors in autoimmune disease. Five diseases are considered: multiple sclerosis, type 1 diabetes, rheumatoid arthritis, autoimmune disease of the thyroid, and inflammatory bowel disease. Clinical relevant studies and factors that may indicate evidence that autoimmune disease is a vitamin D-sensitive disease are presented. Studies that have resulted in prevention or amelioration of some autoimmune disease are discussed. An example of the utility of supplementing vitamin D in an unusual autoimmune disease, idiopathic thrombocytic purpura, is presented.

Rheumatoid arthritis and cancer risk

1996 ◽  
Vol 32 (10) ◽  
pp. 1753-1757 ◽  
Author(s):  
L. Mellemkjær ◽  
M.S. Linet ◽  
G. Gridley ◽  
M. Frisch ◽  
H. Møller ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Cancer Risk

The Molecular basis of Lactose Intolerance

2005 ◽  
Vol 88 (3) ◽  
pp. 157-202 ◽  
Author(s):  
Anthony K. Campbell ◽  
Jonathan P. Waud ◽  
Stephanie B. Matthews
Keyword(s):  
Rheumatoid Arthritis ◽  
Multiple Sclerosis ◽  
Molecular Basis ◽  
Charles Darwin ◽  
Lactose Intolerance ◽  
Anaerobic Bacteria ◽  
Bacterial Toxins ◽  
Systemic Symptoms ◽  
Lactase Gene ◽  
Over 40 Years

A staggering 4000 million people cannot digest lactose, the sugar in milk, properly. All mammals, apart from white Northern Europeans and few tribes in Africa and Asia, lose most of their lactase, the enzyme that cleaves lactose into galactose and glucose, after weaning. Lactose intolerance causes gut and a range of systemic symptoms, though the threshold to lactose varies considerably between ethnic groups and individuals within a group. The molecular basis of inherited hypolactasia has yet to be identified, though two polymorphisms in the introns of a helicase upstream from the lactase gene correlate closely with hypolactasia, and thus lactose intolerance. The symptoms of lactose intolerance are caused by gases and toxins produced by anaerobic bacteria in the large intestine. Bacterial toxins may play a key role in several other diseases, such as diabetes, rheumatoid arthritis, multiple sclerosis and some cancers. The problem of lactose intolerance has been exacerbated because of the addition of products containing lactose to various foods and drinks without being on the label. Lactose intolerance fits exactly the illness that Charles Darwin suffered from for over 40 years, and yet was never diagnosed. Darwin missed something else – the key to our own evolution – the Rubicon some 300 million years ago that produced lactose and lactase in sufficient amounts to be susceptible to natural selection.

Su1843 High Enzyme Activity UGT1A1 or Low Activity Ugt1a8 and Ugt2b4 Genotypes Increase Esophageal Cancer Risk

2012 ◽  
Vol 142 (5) ◽  
pp. S-517
Author(s):  
Polat Dura ◽  
Jody Salomon ◽  
Rene te Morsche ◽  
Hennie Roelofs ◽  
Jon Kristinsson ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Enzyme Activity ◽  
Cancer Risk ◽  
High Enzyme ◽  
Low Activity ◽  
High Enzyme Activity
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