Variation of PI-RADS Interpretations between Experts: A Significant                    Limitation

Jakobi, J. M., and E. Cafarelli. Neuromuscular drive and force production are not altered during bilateral contractions. J. Appl. Physiol. 84(1): 200–206, 1998.—Several investigators have studied the deficit in maximal voluntary force that is said to occur when bilateral muscle groups contract simultaneously. A true bilateral deficit (BLD) would suggest a significant limitation of neuromuscular control; however, some of the data from studies in the literature are equivocal. Our purpose was to determine whether there is a BLD in the knee extensors of untrained young male subjects during isometric contractions and whether this deficit is associated with a decreased activation of the quadriceps, increased activation of the antagonist muscle, or an alteration in motor unit firing rates. Twenty subjects performed unilateral (UL) and bilateral (BL) isometric knee extensions at 25, 50, 75, and 100% maximal voluntary contraction. Total UL and BL force (Δ3%) and maximal rate of force generation (Δ2.5%) were not significantly different. Total UL and BL maximal vastus lateralis electromyographic activity (EMG; 2.7 ± 0.28 vs. 2.6 ± 0.24 mV) and coactivation (0.17 ± 0.02 vs. 0.20 ± 0.02 mV) were also not different. Similarly, the ratio of force to EMG during submaximal UL and BL contractions was not different. Analysis of force production by each leg in UL and BL conditions showed no differences in force, rate of force generation, EMG, motor unit firing rates, and coactivation. Finally, assessment of quadriceps activity with the twitch interpolation technique indicated no differences in the degree of voluntary muscle activation (UL: 93.6 ± 2.51 Hz, BL: 90.1 ± 2.43 Hz). These results provide no evidence of a significant limitation in neuromuscular control between BL and UL isometric contractions of the knee extensor muscles in young male subjects.

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“Optimo humanista et greco”

Erasmus Studies ◽

10.1163/18749275-03502004 ◽

2015 ◽

Vol 35 (2) ◽

pp. 181-209

Author(s):

Brian Richardson

Keyword(s):

Sixteenth Century ◽

Early Career ◽

Significant Limitation ◽

Compare And Contrast

On the death of Aldus Manutius in February 1515, the Venetian diarist Marin Sanudo recorded his evaluation of the man’s achievements, praising him as a teacher and scholar and highlighting the correctness of his Latin and Greek editions and their distinctive prefaces. This article considers the rationale for the esteem shown by Sanudo, and by contemporaries such as Erasmus, for Aldus as an outstanding scholar-printer in the classical languages, examining Sanudo’s suggestions about the means by which Aldus established his business and his reputation in Venice, and the extent to which he made use of collaborations. Sanudo’s assessment has a significant limitation, however, since it omits any mention of printing in Italian. The essay goes on to compare and contrast the production of Aldus’s last year, 1514–1515, which includes vernacular texts as well as editions in Latin and Greek, with that of his early career as a printer in the 1490s, when he concentrated on editions of Greek texts. His vernacular editions had an impact no less important than that of his classical ones in the first half of the sixteenth century, and they made a major contribution to the rise of Italian vernacular scholarship.

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The Benefits and Limitations of Telemedicine During COVID-19

10.4018/978-1-7998-7685-4.ch012 ◽

2022 ◽

pp. 160-167

Author(s):

Bharathi Depuru ◽

Shanthi Sree Kolaru Subramanyam ◽

Suvarna Latha Anchapakala ◽

Lakshmi Padmavathi Pydipati

Keyword(s):

Present Situation ◽

Hospital Staff ◽

The Internet ◽

Significant Limitation ◽

Corona Virus ◽

Chronic Disorders ◽

At Home

Telehealth is effective in preventing, treating, and taking precautions to avoid spreading of coronavirus. Telehealth allows people with symptoms to stay at home by helping them to communicate with doctors through the internet. This decreases the spreading of corona virus to large number of people and hospital staff. But when it comes to treatment of patients, telemedicine does have some limitations. Medicines given through telemedicine may not be consistent to patients who have chronic disorders and makes the patients' conditions serious, which leads them to hospitalization. The most significant limitation of telemedicine is that some hospitals do not have equipment to deliver care in this manner. In the present situation of COVID-19, the existing telemedicine has to be modified for helping quick testing and to diagnose the infection to take care of the patients. Hence, some of the benefits and limitations of telemedicine have been summarized.

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The background of regulating non-bank loan institutions in Poland

Annales Universitatis Mariae Curie-Skłodowska sectio H Oeconomia ◽

10.17951/h.2019.53.2.55-65 ◽

2019 ◽

Vol 53 (2) ◽

pp. 55

Author(s):

Estera Pindel ◽

Czesław Bartłomiej Martysz

Keyword(s):

Consumer Credit ◽

Financial Sector ◽

Bank Loans ◽

Bank Loan ◽

Significant Limitation ◽

Financial Exclusion ◽

Bank Levy ◽

The Law

<p>Non-bank loan institutions in Poland often face a bad reputation or a lack of trust, are compared to "parabanks" and frequently recognised as companies operating at the borders of the law. Despite their membership in the financial sector, until recently, public supervision had little control over loan companies and had little knowledge about the scale of their operations. The greater restrictiveness of the new regulations caused a slowdown in the development of loan companies. Changes such as the introduction of bank levy and the amendment to the Consumer Credit Act of 2016 had a significant impact on the financial results and the structure of products offered by loan companies. Along with the new regulations, however, there is doubt regarding whether these changes, which are intended to organise the market for non-bank loans, will actually lead to an exodus of loan institutions from the market and to significant limitation and financial exclusion on the part of Polish consumers.</p>

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Psychotherapeutic characteristics of schizoid personality

Psychological Counseling and Psychotherapy ◽

10.26565/2410-1249-2018-10-03 ◽

2018 ◽

Keyword(s):

Close Relationships ◽

Subjective Experience ◽

The Body ◽

Internal Conflict ◽

Emotional Experiences ◽

Schizoid Personality ◽

Significant Limitation ◽

Sense Of Security

The article describes the features of psychotherapeutic work with schizoid topic. An understanding of the schizoid psyche in the practical phenomenological direction is considered exclusively under the psychological norm. The main internal conflict of schizoid is described.It shows the strong need for close relationships and the inability to feel comfortably in this proximity. The characteristics of emotional, behavioral, and rational spheres of schizoid individuals are briefly examined. Attention is drawn to features and strategies of psychotherapeutic work with such clients. The first strategy of psychotherapy for a schizoid personality is to create the necessary atmosphere of trust and support, a sense of security in contact with a psychotherapist. The next strategy is to satisfy the demand of a schizoid client to be unconditionally accepted with his unique subjective experience. It is investigated the need for openness and congruence on the part of a therapist. A client in trustful contact with a psychotherapist can recognize his emotional experiences that are unconscious and discarded. Confirmation and reflection of personal feelings in contact with a psychotherapist is sanogenic for a schizoid client. A body-oriented strategy of schizoid-type psychotherapy is considered. The features of the schizoid bodily organization are to block the energy impulses in the muscles. Emotional experiences are disabled due to muscle expression, significant limitation of vital energy in the body. The task of a therapist is to maximally ecologically and fundamentally expand the consciousness of the client to accept personal emotions, needs, experiences and impulses of the body. Client must be ready for a therapist to apply body-oriented techniques. The variants of psychotherapeutic mistakes in work with schizoid dynamics are noted.

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Final Remarks

Implied Licences in Copyright Law ◽

10.1093/oso/9780198858195.003.0014 ◽

2021 ◽

pp. 289-298

Author(s):

Poorna Mysoor

Keyword(s):

Significant Role ◽

Case Law ◽

Copyright Law ◽

Copyright Owner ◽

Significant Limitation ◽

Growing Body ◽

Implied Licence

This concluding chapter explores the advantages of implied licences not only in the offline, but especially in the online world. It sums up the justifications for the conception of ‘implied’ and ‘licence’ adopted in this monograph. It also explains how when faced with the facts and circumstances of a case, how one may ascertain which basis for implying a copyright licence might apply. While acknowledging that express words can override implied licences, it explains why it is not a significant limitation on the usefulness of implied licence, arguing that implied licence can and will continue to play a significant role in copyright law. The growing body of case law on implying a term into a contract is a testament to the fact that there are never going to be complete or comprehensive contracts. There will always be the need to fill in gaps, by way of implying licences based on the conduct of the copyright owner or to give effect to a custom or a policy. The chapter then looks at how implied licences have the potential to play a greater role after the Exit Day.

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Constitutional Law: Supreme Court Indicates Significant Limitation upon Review of State Criminal Procedures

Duke Law Journal ◽

10.2307/1371653 ◽

1967 ◽

Vol 1967 (4) ◽

pp. 857

Keyword(s):

Supreme Court ◽

Constitutional Law ◽

Significant Limitation

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Competing hypotheses and abductive inference

Annals of Mathematics and Artificial Intelligence ◽

10.1007/s10472-019-09630-0 ◽

2019 ◽

Vol 89 (1-2) ◽

pp. 161-178 ◽

Cited By ~ 2

Author(s):

David H. Glass

Keyword(s):

Experimental Results ◽

Abductive Inference ◽

Positive Degree ◽

Significant Limitation ◽

Competing Hypotheses ◽

Exclusive Or

AbstractThis paper explores the nature of competition between hypotheses and the effect of failing to model this relationship correctly when performing abductive inference. In terms of the nature of competition, the importance of the interplay between direct and indirect pathways, where the latter depends on the evidence under consideration, is investigated. Experimental results show that models which treat hypotheses as mutually exclusive or independent perform well in an abduction problem that requires identifying the most probable hypothesis, provided there is at least some positive degree of competition between the hypotheses. However, even in such cases a significant limitation of these models is their inability to identify a second hypothesis that may well also be true.

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