Value in Interventional Radiology: Achieving High Quality Outcomes at a Lower Cost

Radiology ◽  
2020 ◽  
Vol 297 (2) ◽  
pp. 482-483
Author(s):  
Sarah B. White
Author(s):  
T.J. Fraser ◽  
T.L. Knight ◽  
I.M. Knowles ◽  
M.G. Hyslop

Recent developments in cereal breeding for forage production have given the potential to greatly increase annual forage dry matter (DM) production. This paper reports on the findings from two cereal forage production trials on irrigated Canterbury land. Trial 1 studied the potential of a range of single and multi-grazed cereal forages over a 9 month period to produce high yields and quality from both grazing and whole-crop silage forage. Trial 2 studied the suitability of different cereal/ legume combinations for green-chop silage grown over a three month summer period. These two cereal forage systems, when combined in a 12 month period, produced in excess of 25 tonnes of high quality forage per hectare, almost double the DM production achieved using current perennial pasture based systems. Trial 1 showed no significant difference in the total DM produced by either single or multi-graze treatments. In Trial 2 pea/cereal combinations produced over 6 t DM/ha. Due to an earlier final harvest the multi-graze system is more easily combined with the summer crop and more likely to produce a lower cost and more sustainable forage system. Animal performance on forage produced in Trial 1 showed that dairy calves can grow well on cereal forages during winter. Keywords: cereal, feed supplements, forage, forage yield, legume, silage


2016 ◽  
Vol 54 (4) ◽  
pp. 794-823 ◽  
Author(s):  
Ariel White ◽  
Kris-Stella Trump

Local governments operate 311 service request lines across the United States, and the publicly available data from these lines provide a continuously measured, geographically fine-grained, and non-self-reported measure of citizens’ interactions with government. It seems a promising measure of neighborhood political participation. However, these data are empirically and theoretically different from many common citizen-level participation measures. We compare geographically aggregated 311 call data with three other measures of political and civic participation: voter turnout, political donations, and census return rates. We show that rates of 311 calls are negatively related to lower cost activities (voter turnout and census return rates), but positively related to the high-cost activity of campaign donation. We caution against interpreting 311 data as a generic measure of political engagement or participation, at least in the absence of high-quality controls for neighborhood condition. However, we argue that these data are still potentially useful for researchers, because they are by definition a measure of the service demands that neighborhoods place on city governments.


2021 ◽  
Author(s):  
Magaly Martinez ◽  
Phuong-Vi Nguyen ◽  
Maxwell Su ◽  
Fatima Cardozo ◽  
Adriana Valenzuela ◽  
...  

Objectives The objective of the current study was to develop a lower-cost and scalable protocol to identify and monitor SARS-CoV-2 variants in Paraguay by pairing real-time RT-PCR detection of spike mutations with amplicon Sanger sequencing and whole-genome Nanopore sequencing. Methods 201 acute-phase nasopharyngeal samples from SARS-CoV-2-positive individuals were tested with two rRT-PCRs: 1) N2RP assay to confirm SARS-CoV-2 RNA detection (CDC N2 target), and 2) the Spike SNP assay to detect mutations in the spike receptor binding domain. The assay was performed with probes to identify mutations associated with the following variants: alpha (501Y), beta/gamma (417variant/484K/501Y), delta (452R/478K), and lambda (452Q/490S). Results All samples were positive for SARS-CoV-2 in the N2RP assay (mean Ct, 20.8; SD 5.6); 198/201 (98.5%) tested positive in the Spike SNP assay. The most common genotype was 417variant/484K/501Y, detected in 102/198 samples (51.5%) and most consistent with P.1 lineage (gamma variant) in Paraguay. No mutations (K417 only) were found in 64/198 (32.3%); and K417/484K was identified in 22/198 (11.1%), consistent with P.2 (zeta). Seven samples (3.5%) tested positive for 452R without 478K, and one sample with genotype K417/501Y was confirmed as B.1.1.7 (alpha). Results were confirmed by Sanger sequencing in 181/181 samples (100%) with high-quality amplicon sequences, and variant calls were consistent with Nanopore sequencing in 29/29 samples. Conclusions The Spike SNP assay provides accurate detection of mutations associated with SARS-CoV-2 variants. This can be implemented in laboratories performing rRT-PCR to improve population-level surveillance for these mutations and inform the judicious use of scarce sequencing resources.


2015 ◽  
Vol 156 (17) ◽  
pp. 687-695
Author(s):  
Balázs Nemes ◽  
Attila Doros

Interventional radiology provides fast, straightforward and tolerable solutions for many medical problems including acute and subacute situations. Aspiration and drainage of fluid collections, biliary and endourologic interventions and gastrointestinal interventions are parts of non-vascular interventions. In addition, the authors discuss in detail interventional radiological treatment options in patients with hemoptysis. In acute cases interventions must be performed within 12–24 hours. For background, an everyday 24 hours service should be provided with well-trained personnel, high quality equipment and devices, and a reasonable financial reimbursement should be included, too. Multidisciplinary teamwork, consultations, consensus in indications and structured education should make these centers function most effectively. Orv. Hetil., 2015, 156(17), 687–695.


2015 ◽  
Vol 20 (3) ◽  
pp. 159-166 ◽  
Author(s):  
Elizabeth Natividad ◽  
Todd Rowe

Abstract Central venous catheters and peripherally inserted central catheters are fundamental in the delivery of pharmacologic and nutrition therapies to patient populations, including individuals with cancer. Malposition and migration of these catheters outside of the superior or inferior vena cava can contribute to delays in therapy as individuals await repositioning, and in some cases replacement of the catheter. Traditional repositioning using overwire or interventional radiology techniques can be costly and may delay care. The placement and management of these catheters has increasingly become the domain of specially trained vascular access nurses. A team of specially trained vascular access nurses, in collaboration with interventional radiologists at a National Cancer Institute-designated comprehensive cancer center developed a procedure for catheter repositioning using a simultaneous rapid saline flush technique (SRSFT). We present this procedure, along with implications for cost and clinical outcomes. Clinical outcomes suggest that 68% of catheters have been successfully repositioned using this technique with no adverse events associated with the procedure noted to date. In addition, the use of the SRSFT represents a cost savings of up to 90% compared with traditional repositioning procedures. The SRSFT is identified as safe, timely, cost-conscious, and therapeutically effective, although further research is needed to formally evaluate the efficacy of repositioning using this technique compared with overwire and interventional-radiology-guided repositioning, including complications and quality outcomes.


2011 ◽  
Vol 47 (1) ◽  
pp. 99-107 ◽  
Author(s):  
Hanna Lampela ◽  
Annukka Ritvanen ◽  
Silja Kosola ◽  
Antti Koivusalo ◽  
Risto Rintala ◽  
...  

2013 ◽  
Vol 740-742 ◽  
pp. 85-90 ◽  
Author(s):  
Heikki I. Helava ◽  
Evgeny N. Mokhov ◽  
Oleg A. Avdeev ◽  
Mark G. Ramm ◽  
Dmitri P. Litvin ◽  
...  

Recently the wide bandgap semiconductors, silicon carbide (SiC) and aluminum nitride (AlN), have acquired increased importance due to the unique properties that make them applicable to a variety of rapidly-emerging, diverse technologies. In order to meet the challenges posed by these applications the materials need to be manufactured with the highest possible quality, both structural and chemical, at increasingly lower cost. This requirement places rather extreme constraints on the crystal growth as the simultaneous goals of high quality and low cost are generally incompatible. Refractory metal carbide technology, particularly, tantalum carbide (TaC), was originally developed for application in highly corrosive and reactive environments. The SiC group of Prof Yuri A Vodakov (for example, [1]) at Karmon Ltd in St Petersburg, Russia was the first to study and utilize the properties of refractory metal carbides, first for the growth of SiC and later for the growth of AlN. We discuss how the refractory metal carbides can answer many of the problems of growing SiC and AlN in a relatively simple and low cost manner.


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