Melatonin secretion occurs at a constant rate in both young and older men and women

The magnitude and duration of melatonin (MLT) secretion were measured over a period of 25 h with pharmacokinetic studies employing administration of D7MLT at midday and at midnight in two separate studies and two groups of subjects, 12 young and 11 older men and women. Plasma levels of endogenous MLT and D7MLT were quantified separately by use of a specific and sensitive method (gas chromatography-mass spectrometry) previously developed in our laboratory, enabling us to measure endogenous and exogenous MLT levels down to 0.5 pg/ml in plasma. In the two groups of subjects, MLT secretion occurred only at night: onset time of secretion was from 1915 to 2205 (Greenwich mean time), and offset was from 0305 to 0545. No MLT peak was observed in individual nocturnal MLT profiles that were similar to curves obtained for a rate-constant infusion. Modelization demonstrated the superimposition of observed data and simulated curves. MLT concentrations decreasing from the offset of secretion might correspond to the elimination of MLT present in the body at the end of nocturnal secretion. By use of the MLT clearance given by pharmacokinetics, the amount of secreted MLT was found to be 35.7 and 21.6 μg for men and women, respectively, and the rate of secretion was 4.6 and 2.8 μg/h, respectively. No significant gender difference was observed for these two parameters when normalized to body weight. No significant gender difference was observed for onset times of secretion or duration of secretion (7.6–8.6 h) within the two groups, or between young and older subjects.

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Anxiety and the risk of death in older men and women

The British Journal of Psychiatry ◽

10.1192/bjp.185.5.399 ◽

2004 ◽

Vol 185 (5) ◽

pp. 399-404 ◽

Cited By ~ 84

Author(s):

Hein P. J. van Hout ◽

Aartjan T. F. Beekman ◽

Edwin De Beurs ◽

Hannie Comijs ◽

Harm Van Marwijk ◽

...

Keyword(s):

Gender Difference ◽

Anxiety Disorders ◽

Mortality Risk ◽

Older Men ◽

Community Based ◽

Men And Women ◽

Risk Of Death ◽

Screening Design ◽

Older Men And Women

BackgroundThere are inconsistent reports as to whether people with anxiety disorders have a higher mortality risk.AimsTo determine whether anxiety disorders predict mortality in older men and women in the community Method Longitudinal data were used from a large, community-based random sample (n=3107) of older men and women (55–85 years) in The Netherlands, with a follow-up period of 7.5 years. Anxiety disorders were assessed according to DSM–III criteria in a two-stage screening design.ResultsIn men, the adjusted mortality risk was 1.78 (95% Cl 1.01–3.13) in cases with diagnosed anxiety disorders at baseline. In women, no significant association was found with mortality.ConclusionsThe study revealed a gender difference in the association between anxiety and mortality. For men, but not for women, an increased mortality risk was found for anxiety disorders.

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Differential effect of resistance training on the body composition and liporotein-lipid profile in older men and women

Metabolism ◽

10.1016/s0026-0495(99)90162-2 ◽

1999 ◽

Vol 48 (11) ◽

pp. 1474-1480 ◽

Cited By ~ 42

Author(s):

Lyndon J.O. Joseph ◽

Stephanie L. Davey ◽

William J. Evans ◽

Wayne W. Campbell

Keyword(s):

Body Composition ◽

Resistance Training ◽

Lipid Profile ◽

Differential Effect ◽

Older Men ◽

The Body ◽

Men And Women ◽

Older Men And Women

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The Case of Thematic Tests Adapted to Older Adults

Rorschachiana Journal of the International Society for the Rorschach ◽

10.1027/1192-5604/a000015 ◽

2011 ◽

Vol 32 (1) ◽

pp. 46-71 ◽

Cited By ~ 6

Author(s):

Benoît Verdon

Keyword(s):

Older Adults ◽

Older Persons ◽

Older Men ◽

Elderly Persons ◽

Mental Processes ◽

Men And Women ◽

Projective Tests ◽

New Material ◽

Older Men And Women ◽

Latent Content

Since the 1950s, the growing interest of clinicians in using projective tests to study normal or pathological aging processes has led to the creation of several thematic tests for older adults. This development reflects their authors’ belief that the TAT is not suitable to the concerns and anxieties of elderly persons. The new material thus refers explicitly to situations related to age; it aims to enable older persons to express needs they cannot verbalize during consultations. The psychodynamic approach to thematic testing is based on the differentiation between the pictures’ manifest and latent content, eliciting responses linked to mental processes and issues the respondent is unaware of. The cards do not necessarily have to show aging characters to elicit identification: The situations shown in the pictures are linked to loss, rivalry, helplessness, and renunciation, all issues elderly respondents can identify with and that lead them to express their mental fragilities and resources. The article first explains the principles underlying four of these thematic tests, then develops several examples of stories told for card 3BM of the TAT, thus showing the effectiveness of this tool for the understanding and differentiation of loss-related issues facing older men and women.

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Clyde Warrior, 1939–1968

Kalfou A Journal of Comparative and Relational Ethnic Studies ◽

10.15367/kf.v2i1.63 ◽

2015 ◽

Vol 2 (1) ◽

Author(s):

Tiffany Hale

Keyword(s):

Native Americans ◽

Older Men ◽

The United States ◽

Men And Women ◽

Student Nonviolent Coordinating Committee ◽

Political Struggles ◽

Poor People's Campaign ◽

Organizational Leader ◽

Martin Luther King ◽

Older Men And Women

To identify Clyde Warrior as an intellectual subverts prevailing notions of intellectualism. We often think of intellectuals as older men and women whose major contributions are revealed late in life, once the passions of youth have been tempered by experience. Warrior was not this. People frequently imagine intellectuals as existing in isolation, insulated from the demands of regular folk. Warrior was not this either. He was a Ponca, born on the reservation and raised with the influence of his grandparents and community. He was also a renowned singer and powwow fancy dancer, as well as a college student, an organizational leader, a husband, and father of two daughters. Warrior’s political consciousness grew out of the deep connections he maintained to his rural Ponca roots, but he took care to educate himself about the problems affecting Native Americans across the United States as well as colonized peoples globally. As an Oklahoman, he was attuned to race relations in the South and empathized with the struggles of Africans and African Americans. His approach to indigenous political struggles was shaped and informed, for example, by his early and active participation with the Student Nonviolent Coordinating Committee (SNCC) and Martin Luther King Jr.’s Poor People’s Campaign.

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