scholarly journals Ethanol metabolism by alcohol dehydrogenase or cytochrome P4502E1 differentially impairs hepatic protein trafficking and growth hormone signaling

2017 ◽  
Vol 313 (6) ◽  
pp. G558-G569 ◽  
Author(s):  
Erin E. Doody ◽  
Jennifer L. Groebner ◽  
Jetta R. Walker ◽  
Brittnee M. Frizol ◽  
Dean J. Tuma ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Alcohol Dehydrogenase ◽  
Protein Trafficking ◽  
Ethanol Metabolism ◽  
Hormone Signaling ◽  
Differential Effects ◽  
Cytochrome P4502e1

Impaired growth hormone-mediated signaling is observed in ethanol-exposed hepatocytes and is explained by differential effects of alcohol dehydrogenase (ADH)- and cytochrome P4502E1 (CYP2E1)-mediated ethanol metabolism on the Jak2/STAT5B pathway.

Growth hormone signaling and action in obese versus lean human subjects: evidence of increased hepatic GH sensitivity in obesity

2017 ◽  
Author(s):  
Morten Hogild Pedersen ◽  
Ann Mosegaard Bak ◽  
Steen Bonlokke Pedersen ◽  
Niels Jessen ◽  
Niels Moller ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Human Subjects ◽  
Hormone Signaling

1559-P: Differential Effects of Type 1 (T1D) and Type 2 Diabetes (T2D) on the Growth Hormone (GH)-Insulin-Like Growth Factor (IGF) Axis in Youth

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 1559-P
Author(s):  
JANET K. SNELL-BERGEON ◽  
JANE E.B. REUSCH ◽  
AMY D. BAUMGARTNER ◽  
MELANIE CREE-GREEN ◽  
KRISTEN J. NADEAU
Keyword(s):  
Type 2 Diabetes ◽  
Growth Hormone ◽  
Growth Factor ◽  
Insulin Like Growth Factor ◽  
Differential Effects

scholarly journals Dehydrogenase-dependent Ethanol Metabolism in Deer Mice (Peromyscus maniculatus) Lacking Cytosolic Alcohol Dehydrogenase

1989 ◽  
Vol 264 (10) ◽  
pp. 5593-5597
Author(s):  
C Norsten ◽  
T Cronholm ◽  
G Ekström ◽  
J A Handler ◽  
R G Thurman ◽  
...  
Keyword(s):  
Alcohol Dehydrogenase ◽  
Peromyscus Maniculatus ◽  
Ethanol Metabolism ◽  
Deer Mice

scholarly journals Obesity and its impact on COVID-19

2021 ◽  
Author(s):  
Angélica J. M. de Leeuw ◽  
Maureen A. M. Oude Luttikhuis ◽  
Annemarijn C. Wellen ◽  
Christine Müller ◽  
Cornelis F. Calkhoven
Keyword(s):  
Risk Factors ◽  
Growth Hormone ◽  
Healthcare Systems ◽  
Review Literature ◽  
Overweight And Obesity ◽  
Hormone Signaling ◽  
Global Spread ◽  
Number Of Publications ◽  
The Impact ◽  
Sheer Number

AbstractThe severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) pandemic has proven a challenge to healthcare systems since its first appearance in late 2019. The global spread and devastating effects of coronavirus disease 2019 (COVID-19) on patients have resulted in countless studies on risk factors and disease progression. Overweight and obesity emerged as one of the major risk factors for developing severe COVID-19. Here we review the biology of coronavirus infections in relation to obesity. In particular, we review literature about the impact of adiposity-related systemic inflammation on the COVID-19 disease severity, involving cytokine, chemokine, leptin, and growth hormone signaling, and we discuss the involvement of hyperactivation of the renin-angiotensin-aldosterone system (RAAS). Due to the sheer number of publications on COVID-19, we cannot be completed, and therefore, we apologize for all the publications that we do not cite.

scholarly journals Differential Effects of Raloxifene and Estrogen on Body Composition in Growth Hormone-Replaced Hypopituitary Women

2012 ◽  
Vol 97 (3) ◽  
pp. 1005-1012 ◽  
Author(s):  
Vita Birzniece ◽  
Udo J. Meinhardt ◽  
James Gibney ◽  
Gudmundur Johannsson ◽  
Nicola Armstrong ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Body Composition ◽  
Differential Effects
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