Blunted Heart Rate Recovery to Spontaneous Nocturnal Arousals in Short Sleeping Adults

2021 ◽  
Author(s):  
Jeremy A. Bigalke ◽  
Ian M. Greenlund ◽  
Jennifer R. Nicevski ◽  
Carl A. Smoot ◽  
Benjamin Oosterhoff ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Recovery ◽  
Recovery Period ◽  
Sleep Time ◽  
Cardiovascular Complications ◽  
Female Age ◽  
Cardiac Reactivity ◽  
Electrocardiogram Ecg ◽  
The Relationship ◽  
At Home

Chronic insufficient sleep is a common occurrence around the world, and results in numerous physiological detriments and consequences, including cardiovascular complications. The purpose of the present study was to assess the relationship between habitual total sleep time (TST) measured objectively via at-home actigraphy and heart rate (HR) reactivity to nocturnal cortical arousals. We hypothesized that short habitual TST would be associated with exaggerated cardiac reactivity to nocturnal cortical arousals. Participants included in 35 healthy individuals (20 male, 15 female, age: 24 ± 1, BMI: 27 ± 1 kg/m2), and were split using a median analysis into short (SS; n = 17) and normal sleeping (NS; n = 18) adults based on a minimum of 7 days of at-home actigraphy testing. All participants underwent a full overnight laboratory polysomnography (PSG) testing session, including continuous HR (electrocardiogram, ECG) sampling. HR reactivities to all spontaneous cortical arousals were assessed for 20 cardiac cycles following the onset of the arousal in all participants. Baseline HR was not significantly different between groups (P > .05). Spontaneous nocturnal arousal elicited an augmented HR response in the SS group, specifically during the recovery period [F (4.192, 134.134) = 3.413, p = .01]. There were no significant differences in HR reactivity between sexes [F (4.006, 128.189) = .429, p > .05]. These findings offer evidence of nocturnal cardiovascular dysregulation in habitual short sleepers, independent from any diagnosed sleep disorders.

scholarly journals The Relationship Between Heart Rate Recovery and Heart Rate Variability in Coronary Artery Disease

2006 ◽  
Vol 11 (2) ◽  
pp. 154-162 ◽  
Author(s):  
Harun Evrengul ◽  
Halil Tanriverdi ◽  
Sedat Kose ◽  
Basri Amasyali ◽  
Ayhan Kilic ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Coronary Artery ◽  
Heart Rate Recovery ◽  
Artery Disease ◽  
The Relationship

scholarly journals Estimation of the workload in horses during an eventing competition

2013 ◽  
Vol 9 (2) ◽  
pp. 93-101 ◽  
Author(s):  
E. Valle ◽  
R. Odore ◽  
P.R. Zanatta ◽  
P. Badino ◽  
C. Girardi ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Recovery ◽  
Training Session ◽  
Warm Up ◽  
Curve Estimation ◽  
Energy Demands ◽  
Cross Country ◽  
Low Intensity Exercise ◽  
Show Jumping ◽  
The Relationship

The aim of this study was to evaluate workload using suitable parameters related to the physical effort exerted by horses involved in eventing competitions in order to describe the workload intensity and energy demands placed upon such horses. Heart rate (HR), running speed (S), distance covered (Dist), performance duration (D) and blood lactate (Lact) concentrations were measured in horses competing at either the intermediate level (IL) or advanced level (AL) in order to identify workload differences between experience classes. Ten warmblood horses were monitored during an official two-day eventing competition; mean HR (HRmean, bpm), maximum HR (HRmax, bpm), mean S (Smean, m/min), max S (Smax, m/min), D (min) and Dist (m) were assessed during the warm-up and competition phases of each eventing test (dressage, show jumping, cross country). To calculate heart rate recovery (HRR), HR data were collected within the first 3 minutes following the completion of each of the 3 competition phases. Energy expenditure (EE) was estimated using the HR/VO2 relationship. Differences between the groups (AL vs. IL) in HRmean, HRmax, %HRmean, %HRpeak (HR expressed as a percentage of the maximum HR peak obtained during a fast gallop training session), S, D, and Dist were assessed using one-tailed unpaired t-tests for both warmup and competition phases; also differences for EE were evaluated. The relationship between HR and S was also determined for warm-up and competition phases using one-tailed Person's correlations. The relationship between HR decrease during the first 3 min following competition phase completion and recovery time was investigated by multiple nonlinear curve estimation procedures. The results reveal the cross country test to be the most demanding of the eventing competition, requiring significantly greater levels of muscular and energetic effort, in terms of Lact production and EE, with higher values recorded in the AL horses compared to IL horses. The data also show that riders need to optimise warm-up duration and quality in accordance with their competition category. The calculation of HRR is also shown to be an appropriate approach for gauging workload after high-intensity exercise, but not after low-intensity exercise since HRR may be influenced by external factors, like how excited a horse is.

scholarly journals The Relationship Between the Heart Rate Performance Curve Deflection and the Heart Rate Recovery

2004 ◽  
Vol 36 (Supplement) ◽  
pp. S332
Author(s):  
Melanie Luger ◽  
Rochus Pokan ◽  
Peter Hofmann ◽  
Serge P. von Duvillard
Keyword(s):  
Heart Rate ◽  
Heart Rate Recovery ◽  
Performance Curve ◽  
Rate Performance ◽  
The Relationship

scholarly journals Decreased heart rate recovery may predict a high SYNTAX score in patients with stable coronary artery disease

2019 ◽  
Vol 19 (1) ◽  
pp. 109-115
Author(s):  
Sadık Volkan Emren ◽  
Rahman Bilal Gediz ◽  
Oktay Şenöz ◽  
Uğur Karagöz ◽  
Ersin Çağrı Şimşek ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Heart Rate ◽  
Coronary Artery ◽  
Heart Rate Recovery ◽  
Stable Coronary Artery Disease ◽  
Recovery Period ◽  
Multivariate Logistic Regression Analysis ◽  
Syntax Score ◽  
Increased Risk ◽  
Artery Disease

An impaired heart rate recovery (HRR) has been associated with increased risk of cardiovascular events, cardiovascular, and all‐cause mortality. However, the diagnostic ability of HRR for the presence and severity of coronary artery disease (CAD) has not been clearly elucidated. Our aim was to investigate the relationship between HRR and the SYNTAX (SYNergy between percutaneous coronary intervention with TAXus and cardiac surgery) score in patients with stable CAD (SCAD). A total of 406 patients with an abnormal treadmill exercise test and ≥50% coronary stenosis on coronary angiography were included. The HRR was calculated by subtracting the HR in the first minute of the recovery period from the maximum HR during exercise. The SYNTAX score ≥23 was accepted as high. Correlation of HRR with SYNTAX score and independent predictors of high SYNTAX score were determined. A high SYNTAX score was present in 172 (42%) patients. Mean HRR was lower in patients with a high SYNTAX score (9.8 ± 4.5 vs. 21.3 ± 9, p < 0.001). The SYNTAX score was negatively correlated with HRR (r: -0.580, p < 0.001). In multivariate logistic regression analysis, peripheral arterial disease (OR: 13.3; 95% CI: 3.120–34.520; p < 0.001), decreased HRR (OR: 0.780; 95% CI: 0.674–0.902; p = 0.001), peak systolic blood pressure (OR: 1.054; 95% CI: 1.023–1.087; p = 0.001), and peak HR (OR: 0.950; 95% CI: 0.923–0.977; p < 0.001) were found to be independent predictors of a high SYNTAX score. Our results showed that HRR is significantly correlated with the SYNTAX score, and a decreased HRR is an independent predictor of a high SYNTAX score in patients with SCAD.

scholarly journals Associations of Blood Pressure and Heart Rate and Their Contribution to the Development of Cardiovascular Complications and All-Cause Mortality in the Russian Population of 25-64 Years

2020 ◽  
Vol 16 (5) ◽  
pp. 759-769
Author(s):  
S. A. Shalnova ◽  
V. A. Kutsenko ◽  
A. V. Kapustina ◽  
E. B. Yarovaya ◽  
Yu. A. Balanova ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Cardiovascular Complications ◽  
Adverse Outcomes ◽  
Average Value ◽  
Risk Of Mortality ◽  
The Right ◽  
Relationship Of ◽  
The Relationship

Aim. To study the relationship of blood pressure (BP) and heart rate (HR) in a sample of men and women 25-64 years old and their predictive value for the development of fatal and non-fatal cardiovascular diseases (CVD) and mortality from all causes.Material and methods. Prospective observation was for cohorts of the population aged 25-64 years from 11 regions of the Russian Federation. 18,251 people were included in the analysis. Each participant gave written informed consent. All surveyed persons were interviewed with a standard questionnaire. BP was measured on the right hand with an automatic tonometer. BP and HR were measured twice with an interval of 2-3 min with the calculation of the average value. The patients were divided into 4 groups: the first group with BP<140/90 ><140/90 mm Hg and HR≤80 beats/min; the second group – BP<140/><140/90 mm Hg and HR>80; the third group – BP≥140/90 mm Hg and HR≤80; the fourth group – BP≥140/90 mm Hg and HR>80 beats/min. Risk factors and cardiovascular history were analyzed as well. Deaths over 6 years of follow-up occurred in 393 people (141 – from CVD). Statistical analysis was performed using the open source R3.6.1 system.Results. A HR>80 beats/min was found in 26.3% of people with BP≥140/90 mm Hg, regardless of medication. Analysis of the associations between HR and BP showed that for every increase in HR by 10 beats/min, systolic BP increases by 3 mm Hg. (p<0.0001). The group with HR>80 beats/min and BP≥140/90 mm Hg had the shortest life expectancy (p<0.001). Adding an increased HR to BP≥140/90 mm Hg significantly><0.001). Adding an increased HR to BP≥140/90 mm Hg significantly worsened the prognosis of patients. Similar results were obtained in the analysis of cardiovascular survival. Elevated BP and elevated HR had the same effect on outcomes, except for the combined endpoint, where the contribution of elevated BP was predominant. However, their combined effect was the largest and highly significant for the development of the studied outcomes, even after adjusting for other predictors. With an increase in HR by every 10 beats/min, the risk of mortality increased statistically significantly by 22%.Conclusion. The prevalence of HR>80 beats/min in people with BP≥140 mm Hg amounted to 26.34%. Every 10 beats/min significantly increases the risk of mortality by 22%. Increased HR with elevated BP leads to increased adverse outcomes.

The Relationship Between the Heart Rate Performance Curve Deflection and the Heart Rate Recovery

2004 ◽  
Vol 36 (Supplement) ◽  
pp. S332
Author(s):  
Melanie Luger ◽  
Rochus Pokan ◽  
Peter Hofmann ◽  
Serge P. von Duvillard
Keyword(s):  
Heart Rate ◽  
Heart Rate Recovery ◽  
Performance Curve ◽  
Rate Performance ◽  
The Relationship

500 Late-Breaking: Heart Rate During Exercise Is Positively Correlated with State IV Mitochondrial Respiration in the Equine Skeletal Muscle

2021 ◽  
Vol 99 (Supplement_3) ◽  
pp. 105-106
Author(s):  
Mia Y Kawaida ◽  
Oh-Sung Kwon ◽  
Ahram Anh ◽  
Amanda S Reiter ◽  
Nicole M Tillquist ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Heart Rate ◽  
Oxidative Phosphorylation ◽  
Mitochondrial Respiration ◽  
Recovery Period ◽  
Proton Leak ◽  
Semitendinosus Muscle ◽  
Exercise Tests ◽  
Cardiac Responses ◽  
The Relationship

Abstract Mitochondria are critical for oxidative phosphorylation in skeletal muscle, especially in athletic species such as the horse. Mitochondrial respiration increases with physical exercise, but the relationship between mitochondrial respiration and cardiovascular functions are not well described in the horse. The objective of this study was to determine if there is a relationship between heart rate (HR) during and after submaximal exercise tests (SETs) and skeletal muscle mitochondrial respiration in polo ponies. We hypothesized that horses with greater maximum HR and average HR during the exercise tests would have greater mitochondrial respiration in skeletal muscle. Twelve fit polo ponies (14.8 ± 1.7 years old, 10 mares and 2 geldings) were equipped with Polar equine heart rate monitors (Polar Electro Inc., Lake Success, NY) and underwent 26-minute SETs designed to mimic a polo chukker followed by a 30-minute recovery period. Muscle biopsy samples from the semitendinosus muscle were taken 2 weeks prior to the SET to determine mitochondrial oxygen consumption using the Oroboros O2k high-resolution respirometer (Oroboros Instruments, Innsbruck, Austria). Data were analyzed using the PROC CORR procedure (SAS Inst. Inc., Cary, NC). Correlations were considered strong at r &gt; 0.6 and significant at P &lt; 0.05. Maximum HR during SET and state IV respiration were positively correlated (P = 0.02, r = 0.68). Average HR during SET and state IV respiration were also positively correlated (P = 0.01, r = 0.72). However, correlations between maximum and average HR and state III respiration were not as strong (P ≥ 0.05, r &lt; 0.6). These data suggest that state IV mitochondrial respiration (proton leak) in equine skeletal muscle may impact cardiac responses to high-intensity exercise. Horses with higher HR during exercise may have less efficient oxidative phosphorylation, resulting in earlier fatigue and/or greater formation of reactive oxygen species resulting from proton leak.

Mechanism of failure of recovery from hypoxic apnea by gasping in 17- to 23-day-old mice

1991 ◽  
Vol 71 (3) ◽  
pp. 1098-1105 ◽  
Author(s):  
M. S. Jacobi ◽  
W. M. Gershan ◽  
B. T. Thach
Keyword(s):  
Heart Failure ◽  
Heart Rate ◽  
Survival Rate ◽  
Heart Rate Recovery ◽  
Severe Heart Failure ◽  
High O2 ◽  
Respiratory Centers ◽  
Mechanism Of Failure ◽  
Electrocardiogram Ecg ◽  
Old Mice

The mechanism of failure of autoresuscitation from hypoxic apnea in 17- to 23-day-old (weanling) Swiss Webster related/J mice was investigated by recording electrocardiogram (ECG) and ventilation in adult, weanling, and 11-day-old mice. Hypoxic apnea was induced with 97% N2–3% CO2. O2 (21% or 50% O2) or 97% N2–3% CO2 was given at the onset of apnea. The ECG showed no arrhythmias predictive of failure of autoresuscitation. The first indication of failure was a progressive fall in gasp volume (“run down”). This pattern also occurred in animals given continuous 97% N2–3% CO2 and was significantly different from that in mice that survived. Gasping duration in 97% N2 was longer in weanlings than adults but shorter than in 11 day olds. Respiratory and heart rate recovery were more rapid in adults than in weanlings. Although recovery in high O2 was more rapid, the survival rate was not increased. The lack of effect of high O2 on survival and the virtually identical pattern of gasping in mice dying in 97% N2 and air leads us to conclude that in mice that fail to autoresuscitate little or no O2 reaches the medullary respiratory centers. We speculate that this may be due to increased vulnerability of cardiac muscle to anoxia in 17- to 23-day-old mice, resulting in early and severe heart failure.

scholarly journals Deterioration of heart rate recovery index in patients after carotid artery stenting

2017 ◽  
Vol 23 (6) ◽  
pp. 578-582
Author(s):  
Emrah Aytac ◽  
Murat Gonen ◽  
Orhan Dogdu ◽  
Mehmet Balin
Keyword(s):  
Heart Rate ◽  
Carotid Artery ◽  
Exercise Testing ◽  
Carotid Artery Stenting ◽  
Heart Rate Recovery ◽  
Recovery Period ◽  
Exercise Stress ◽  
Peak Exercise ◽  
Maximal Heart Rate ◽  
Metabolic Equivalents

Objective Although carotid artery stenting (CAS) is an effective treatment for severe carotid stenosis, it has been associated with alterations in autonomic functions long term after the procedure. Patients with CAS have been reported to have autonomic nervous system (ANS) dysfunction. This study aimed to evaluate heart rate recovery (HRR) indices and exercise test parameters after CAS. Methods Patients (10 male, 11 female) suitable for CAS, without a history of hypertension, diabetes mellitus, severe coronary artery or valvular heart disease, were enrolled in our study. Basal electrocardiography, echocardiography, and treadmill exercise testing were performed in all patients pre- and post-procedure. The HRR index was defined as the reduction in the heart rate from the rate at peak exercise to the rate first minute (HRR1), second minute (HRR2), third minute (HRR3) and fifth minute (HRR5) after the cessation of exercise stress testing. Results The exercise time, maximal heart rate, maximal blood pressure and maximal metabolic equivalents values were significantly decreased after the procedure. The first- and second-minute HRR indices of patients before procedure were significantly lower than after procedure (23.5 ± 6.6 vs 25.8 ± 8.3; p < 0.001 and 41.8 ± 12.3 vs 50.2 ± 16.3; p < 0.001, respectively). Similarly, HRR indices after the third and fifth minutes of the recovery period were significantly lower in patients before procedure, when compared with those indices after procedure (52.9 ± 13.1 vs 60.7 ± 14.4; p < 0.001 and 62.4 ± 12.8 vs 71.9 ± 14.1; p < 0.001). Conclusion We have demonstrated that HRR indices increased in the first, second, third and fifth minutes of the recovery period after maximal exercise testing in patients after the CAS procedure, which may be a reflection of parasympathetic dominance after CAS.

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