Two weeks of high-intensity interval training improves novel but not traditional cardiovascular disease risk factors in adolescents

2015 ◽  
Vol 309 (6) ◽  
pp. H1039-H1047 ◽  
Author(s):  
Bert Bond ◽  
Emma J. Cockcroft ◽  
Craig A. Williams ◽  
Sam Harris ◽  
Phillip E. Gates ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
Aerobic Fitness ◽  
High Intensity ◽  
Interval Training ◽  
High Intensity Interval Training ◽  
Cvd Risk Factors ◽  
Cvd Risk ◽  
Postprandial State ◽  
High Intensity Interval

High-intensity interval training (HIIT) improves traditional cardiovascular disease (CVD) risk factors in adolescents, but no study has identified the influence of HIIT on endothelial and autonomic function in this group. Thirteen 13- to 14-yr-old adolescents (6 girls) completed six HIIT sessions over 2 wk. Each training session consisted of eight to ten 1-min repetitions of cycling at 90% peak power interspersed with 75 s of unloaded cycling. Traditional (triglycerides, cholesterol, glucose, insulin, and blood pressure) and novel [flow-mediated dilation (FMD), heart rate variability (HRV)] CVD risk factors were assessed in a fasted and postprandial state before (PRE), 1 day after (POST-1D), and 3 days after (POST-3D) training. Aerobic fitness was determined PRE and POST-3D. Two weeks of HIIT had no effect on aerobic fitness or traditional CVD risk factors determined in the fasted or postprandial state ( P > 0.15). Compared with PRE, fasted FMD was improved POST-1D [ P = 0.003, effect size (ES) = 0.70] but not POST-3D ( P = 0.32, ES = 0.22). Fasted FMD was greater POST-1D compared with POST-3D ( P = 0.04, ES = 0.48). Compared with PRE, postprandial FMD was greater POST-1D ( P < 0.001, ES = 1.01) and POST-3D ( P = 0.01, ES = 0.60). Fasted HRV was greater POST-1D ( P = 0.001, ES = 0.71) and POST-3D ( P = 0.02, ES = 0.44). The test meal lowered HRV in all laboratory visits ( P < 0.001, ES = 0.59), but there were no differences in postprandial HRV between visits ( P > 0.32 for all). Two weeks of HIIT enhanced endothelial function and HRV without improvements in traditional CVD risk factors. However, most of this favorable adaptation was lost POST-3D, suggesting that regularly performing high-intensity exercise is needed to maintain these benefits.

scholarly journals Effect of high-intensity interval training on cardiovascular disease risk factors and body composition in psoriatic arthritis: a randomised controlled trial

RMD Open ◽  
2018 ◽  
Vol 4 (2) ◽  
pp. e000729
Author(s):  
Ruth Stoklund Thomsen ◽  
Tom Ivar Lund Nilsen ◽  
Glenn Haugeberg ◽  
Anja Bye ◽  
Arthur Kavanaugh ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
Psoriatic Arthritis ◽  
Interval Training ◽  
Control Group ◽  
High Intensity Interval Training ◽  
Cvd Risk Factors ◽  
Fat Percentage ◽  
Cvd Risk ◽  
High Intensity Interval

BackgroundPsoriatic arthritis (PsA) is associated with an accumulation of cardiovascular disease (CVD) risk factors. The aim of this study was to evaluate the effect of high-intensity interval training (HIIT) on CVD risk factors in patients with PsA.MethodsWe randomly assigned 61 patients with PsA (41 women and 20 men) to an intervention group performing HIIT for 11 weeks or a control group who were instructed to not change their physical exercise habits. Outcomes were assessed at 3 and 9  months with measures on maximal oxygen uptake (VO2max), fat percentage and Body Mass Index (BMI). We used linear mixed models to calculate mean difference with 95% CI between the groups according to the intention-to-treat principle.ResultsAt 3  months, the HIIT group had a 3.72  mL/kg/min (95%  CI 2.38 to 5.06) higher VO2max and a 1.28 (95% CI −2.51 to −0.05) lower truncal fat percentage than controls. There was also some evidence that the HIIT group had lower total fat percentage (−0.80; 95%  CI −1.71 to 0.10) and slightly lower BMI (−0.31; 95%  CI −0.78 to 0.17) than the control group. At 9  months, the HIIT group had still a higher VO2max (3.08; 95%  CI 1.63 to 4.53) than the control group, whereas the difference in other factors were small.ConclusionIn patients with PsA, 3  months with HIIT was associated with a substantial increase in VO2max and a reduction in truncal fat percentage compared with controls. The beneficial effect on VO2max was also sustained through 9  months.Trial registration numberNCT02995460.

scholarly journals Low-volume high-intensity interval training for children with obesity: a commentary

2020 ◽  
Vol 26 ◽  
pp. 7-15
Author(s):  
Jaak Jürimäe
Keyword(s):  
Risk Factors ◽  
Body Mass ◽  
High Intensity ◽  
Interval Training ◽  
High Intensity Interval Training ◽  
Cvd Risk ◽  
Common Chronic Disease ◽  
Low Volume ◽  
High Intensity Interval ◽  
Associated Risk Factors

Obesity is the most common chronic disease in childhood, and is a risk factor for cardiovascular diseases (CVD) later in life. Being obese is inversely associated with physical activity and cardiorespiratory fitness (CRF) in children. Increased CRF may negate the detrimental effects of obesity-associated risk factors for CVD, while poor CRF has been associated with increased arterial stiffness and higher levels of blood inflammatory markers. The use of time efficient high-intensity interval training (HIIT) to reduce CVD risk factors and body mass, improve CRF and other health parameters has become popular during the last years in adults with obesity. However, a relatively few studies have investigated the effect of HIIT on body composition, CRF and cardiometabolic biomarkers in children with obesity. It is expected that low-volume HIIT programs are feasable for community-based body mass reduction and health promotion in children with obesity.

scholarly journals PL-001 Home-Based High-Intensity Interval Training Improves Muscle Capillarisation and eNOS/NAD(P)Hoxidase Protein Ratio in Obese Individuals with Elevated Cardiovascular Disease Risk

2018 ◽  
Vol 1 (1) ◽  
Author(s):  
Sam Scott ◽  
Sam Shepherd ◽  
Jay Wright ◽  
Robert Copper ◽  
Anton Wagenmakers ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
High Intensity ◽  
Disease Risk ◽  
Interval Training ◽  
Whole Body ◽  
Moderate Intensity ◽  
High Intensity Interval Training ◽  
Cvd Risk ◽  
Home Based ◽  
High Intensity Interval

Objective Obesity and inactivity lead to structural and functional muscle microvascular impairments associated with development of chronic disease. This study is the first to investigate the effect of a novel home-based high-intensity interval training (HIT) (Home-HT) intervention in obese individuals with elevated cardiovascular disease (CVD) risk on capillarisation and muscle microvascular eNOS/NAD(P)Hoxidase ratio. Comparisons were made with home-based moderate-intensity continuous training (Home-MICT) and supervised laboratory-based low-volume HIT (Lab-HIT) as control groups. Methods Thirty-two sedentary obese adults (age 36±2 years; BMI 34.3±0.8 kg∙m-2; O2peak24.6±1.0 ml∙kg-1∙min-1) were allocated to 12 weeks of Home-HIT (n=9), Home-MICT (n=13) or Lab-HIT (n=10). Muscle biopsies were taken pre- and post-training to assess specifically in the endothelial layer of muscle arterioles and capillaries the protein content of eNOS, serine1177phosphorylated eNOS, NOX2 and p47phox, and various capillarisation measures using quantitative immunofluorescence microscopy. Results All interventions induced comparable increases in total eNOS content in terminal arterioles and capillaries (P<0.001). There was no change in ser1177phosphorylated eNOS (arterioles P=0.802; capillaries P=0.311), but eNOS ser1177/eNOS ratio significantly decreased following training in arterioles and capillaries (P<0.001). Training decreased NOX2 content (arterioles P<0.001; capillaries P<0.001), but there was no change in p47phoxcontent (arterioles P=0.101; capillaries P=0.345). All measures of capillarisation increased (P<0.05). These adaptations occurred alongside increased O2peak(P<0.001) and whole-body insulin sensitivity (P=0.033). There were no significant differences between training programmes. Conclusions The training effects of Home-HIT on skeletal muscle microvascular adaptations are comparable to those of traditional training methods, with the advantage that Home-HIT reduces barriers to exercise in obese individuals with elevated CVD risk.

High-Intensity Interval Training and Cardiometabolic Risk Factors in Children: A Meta-analysis

PEDIATRICS ◽  
2021 ◽  
Vol 148 (4) ◽  
pp. e2021050810
Author(s):  
Monserrat Solera-Martínez ◽  
Ángel Herraiz-Adillo ◽  
Ismael Manzanares-Domínguez ◽  
Lidia Lucas De La Cruz ◽  
Vicente Martínez-Vizcaíno ◽  
...  
Keyword(s):  
Risk Factors ◽  
High Intensity ◽  
Cardiometabolic Risk ◽  
Meta Analysis ◽  
Interval Training ◽  
Cardiometabolic Risk Factors ◽  
High Intensity Interval Training ◽  
High Intensity Interval

scholarly journals Light-intensity and high-intensity interval training improve cardiometabolic health in rats

2016 ◽  
Vol 41 (9) ◽  
pp. 945-952 ◽  
Author(s):  
Romeo B. Batacan ◽  
Mitch J. Duncan ◽  
Vincent J. Dalbo ◽  
Kylie J. Connolly ◽  
Andrew S. Fenning
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Light Intensity ◽  
High Intensity ◽  
Cardiometabolic Risk ◽  
Interval Training ◽  
Cardiometabolic Risk Factors ◽  
Cardiac Conduction ◽  
High Intensity Interval Training ◽  
High Intensity Interval

Physical activity has the potential to reduce cardiometabolic risk factors but evaluation of different intensities of physical activity and the mechanisms behind their health effects still need to be fully established. This study examined the effects of sedentary behaviour, light-intensity training, and high-intensity interval training on biometric indices, glucose and lipid metabolism, inflammatory and oxidative stress markers, and vascular and cardiac function in adult rats. Rats (12 weeks old) were randomly assigned to 1 of 4 groups: control (CTL; no exercise), sedentary (SED; no exercise and housed in small cages to reduce activity), light-intensity trained (LIT; four 30-min exercise bouts/day at 8 m/min separated by 2-h rest period, 5 days/week), and high-intensity interval trained (HIIT, four 2.5-min work bouts/day at 50 m/min separated by 3-min rest periods, 5 days/week). After 12 weeks of intervention, SED had greater visceral fat accumulation (p < 0.01) and slower cardiac conduction (p = 0.04) compared with the CTL group. LIT and HIIT demonstrated beneficial changes in body weight, visceral and epididymal fat weight, glucose regulation, low-density lipoprotein cholesterol, total cholesterol, and mesenteric vessel contractile response compared with the CTL group (p < 0.05). LIT had significant improvements in insulin sensitivity and cardiac conduction compared with the CTL and SED groups whilst HIIT had significant improvements in systolic blood pressure and endothelium-independent vasodilation to aorta and mesenteric artery compared with the CTL group (p < 0.05). LIT and HIIT induce health benefits by improving traditional cardiometabolic risk factors. LIT improves cardiac health while HIIT promotes improvements in vascular health.

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