Hematological changes in deer mice acclimated at different ambient temperatures

1960 ◽  
Vol 198 (1) ◽  
pp. 195-199 ◽  
Author(s):  
John A. Sealander
Keyword(s):  
Hemoglobin Concentration ◽  
Deer Mice ◽  
Mean Corpuscular Hemoglobin ◽  
Mean Corpuscular Hemoglobin Concentration ◽  
Corpuscular Hemoglobin ◽  
Ambient Temperatures ◽  
Significant Difference ◽  
Similar Temperature ◽  
The Mean ◽  
Hematological Changes

Deer mice ( Peromyscus maniculatus and Peromyscus leucopus) were acclimated at temperatures of 5° ±0.5°C and 30°±0.5°C for various intervals with periods at 20°±0.5°C preceding the cold and warm acclimation periods. Hemoglobin concentrations, hematocrits and erythrocyte diameters were measured on a group of nonsplenectomized mice and on another group of splenectomized mice which were subjected to similar temperature conditions. It was found that there were significant increases in hemoglobin and hematocrit values with acclimation at 5°C, which were more marked in the splenectomized mice. Differences in hemoglobin concentrations and hematocrits were significant between 5° and 30°C, but differences were not as apparent between mice at 30°C and those exposed at 20°C. There were no significant changes in erythrocyte diameters, although the mean corpuscular hemoglobin concentration was significantly lower in all of the splenectomized mice as opposed to the nonsplenectomized ones. It is suggested that splenectomy in some way enhances erythopoiesis in response to low temperature since there was no significant difference in hematocrits of nonsplenectomized and splenectomized mice exposed at 20°C prior to cold acclimation.

scholarly journals HEMATOLOGICAL CHARACTERIZATION OF BETA-THALASSEMIA IN SUDANESE PATIENTS

2020 ◽  
pp. 5-7
Author(s):  
RABAB HASSAN ELSHAIKH ◽  
SANAA ELFATIH HUSSEIN
Keyword(s):  
Iron Deficiency ◽  
Hemoglobin Concentration ◽  
Mean Value ◽  
Beta Thalassemia ◽  
Mean Corpuscular Hemoglobin ◽  
Corpuscular Hemoglobin ◽  
Significant Difference ◽  
Hematological Analysis ◽  
The Mean

Thalassemia is common inherited disorder among humans, and they represent a major public health problem in many areas of the world. The study aimed to the measurement of hematological characterization of beta-thalassemia in Sudanese patients. Blood samples from 61 beta-thalassemic patients were collected after written consent form obtained from all participants. The frequency of adults (>18 years) was 45 (73.8%) and children’s (<18 years) was 16 (26.2%); the frequency of male was 27 (44.3%) and 34 were female (55.7%). Hemoglobin estimation and red cell indices were carried out using the automatic blood cell counter Sysmex K × 21N. The results showed that Hb and RBCs indices were varied between mild to moderate and severe decreasing, hemoglobin concentration (Hb) with the mean value of 9.6 g/dL, with minimum value of 6.1 g/dl and maximum of 11.9 g/dl, while RBCs were increased in all patients, mean value 5.2 c/l, mean corpuscular volume mean was 58.9 fl, hematocrit was 30.4, mean corpuscular hemoglobin (MCH) 18.8 pg, mean corpuscular hemoglobin concentration (MCHC) was 31.7pg, and RDW was 18.8%. The method used for hemoglobin electrophoresis was capillary electrophoresis, Hb pattern shows increased HbA2 and HbF, the mean of HbA is 78.3%, HbF is 2.3%, and HbA2 is 6.5% with the min. value of 3.6% and max. of 12.2%. While the mean of serum iron was 82.75 μg/dl, 7 patients showed low level, 19 high level, and 35 were normal level. Comparison of hematological analysis (HbA2) in thalassemic patients coexisted with iron deficiency and without result was insignificant difference (p=0.645), this result disagrees with references that say iron deficiency masking HbA2. Nevertheless, the association between HbA2 and HbF revealed a statistically significant difference (p<0.013) and HbA2 with Hb was insignificant (p=0.260).

scholarly journals Blood Donation in Nigeria: Standard of the Donated Blood

2012 ◽  
Vol 4 (02) ◽  
pp. 094-097 ◽  
Author(s):  
Nwogoh Benedict ◽  
Awodu Omolade Augustina ◽  
Bazuaye Godwin Nosakhare
Keyword(s):  
Blood Donation ◽  
Hematological Parameters ◽  
Hemoglobin Concentration ◽  
Mean Corpuscular Hemoglobin ◽  
Corpuscular Hemoglobin ◽  
Mean Cell Volume ◽  
Benin City ◽  
Cell Counts ◽  
Significant Difference ◽  
The Mean

ABSTRACT Objective: The objective was to determine the basic hematological parameters of remunerated blood donors in Benin City and to compare them with those of voluntary donors. Materials and Methods: This is a prospective study conducted in a tertiary health facility in Benin City. Pretransfusion samples were obtained from blood bags after gentle mixing and analyzed for hematological parameters. Samples were analyzed using the hematology autoanalyzer MODEL SYSMEX KN21. Result: A total of 215 samples were obtained comprising 160 remunerated (paid) and 55 voluntary donor samples. In the paid donors, the mean hemoglobin concentration (Hb) and hematocrit (HCT) 7.7±2.9 and 28.8±8.5 respectively. This was significantly lower than those of voluntary donors who had 13.9±1.2 and 42.2±3.3 with P < 0.001. The mean values of the red cell counts (RBC), white cell counts (WBC), mean cell volume (MCV), mean corpuscular hemoglobin (MCH), and mean corpuscular hemoglobin concentration (MCHC) were significantly lower in paid donors as P-values were <0.001. MCV was significantly low but not compared to the other parameters as P=0.04. There was no significant difference in the platelet count. Conclusion: Paid donors in Benin City have significantly lower hematological parameters than controls.

scholarly journals Profile of Haematology and Biochemistry of Aceh Polled and Horned Cow

2020 ◽  
Vol 151 ◽  
pp. 01056
Author(s):  
Yudha Fahrimal ◽  
Nuzul Asmilia ◽  
Siti Aisyah ◽  
Fitri R. Yanti ◽  
Erina Erina ◽  
...  
Keyword(s):  
Hemoglobin Concentration ◽  
Blood Biochemistry ◽  
Mean Corpuscular Hemoglobin ◽  
Mean Corpuscular Hemoglobin Concentration ◽  
Corpuscular Hemoglobin ◽  
Blood Profile ◽  
Significant Difference ◽  
Total Glucose ◽  
Harsh Conditions ◽  
Better Than

As one of the Local wisdom in Aceh, farmer prefers raising polled cow than horned cow for breeding purposes. They believe pole cow is more resilient in harsh conditions and reproductively better than the horned cow. The aim of this study was to evaluate blood profile and blood biochemistry of the aceh polled and horned cow. The blood profile examined includes erythrocyte value, erythrocyte indices MCV (Mean Corpuscular Volume), MCH (Mean Corpuscular Hemoglobin), MCHC (Mean Corpuscular Hemoglobin Concentration), thrombocyte, leukocyte, hematocrit, and hemoglobin, while blood biochemistry includes protein total, glucose, cholesterol, and ureum. Blood was collected from 15 aceh horned and 15 pole cow raised at Research Institute of Improved Livestock and Livestock Fodder (BPTU HPT) Indrapuri, Aceh Besar regency, province of Aceh, Indonesia. The cows were clinically healthy and aged 1,5-2,5 years old. Blood profile was measured using a hematology analyzer and blood biochemistry was measured using a Yuesen Med and Spectrophotometer. Based on the statistic analysis, blood profile and blood biochemistry of the aceh horned and polled cow on all parameters showed no significant difference (p>0,05). It is therefore concluded that there are no different value of blood profile and blood biochemistry between polled and horned cow.

Copper and Copper Nanoparticles Induced Hematological Changes in a Freshwater Fish Labeo rohita – A Comparative Study

2016 ◽  
pp. 352-375
Author(s):  
Kaliappan Krishnapriya ◽  
Mathan Ramesh
Keyword(s):  
Blood Cells ◽  
Mean Corpuscular Volume ◽  
Labeo Rohita ◽  
White Blood Cells ◽  
Hemoglobin Concentration ◽  
Mean Corpuscular Hemoglobin ◽  
Mean Corpuscular Hemoglobin Concentration ◽  
Corpuscular Hemoglobin ◽  
Treated Fish ◽  
Hematological Changes

In the present study, fish Labeo rohita were exposed to 20, 50 and 100 µg/L of both Cu NPs and copper sulphate (CuSO4, bulk copper) for 24 h and hematological profiles were estimated. A significant (P< 0.01) change in the hemoglobin (Hb), hematocrit (Hct), white blood cells (WBC) and Mean Corpuscular Volume (MCV) levels were observed in all the three concentrations of both bulk and Cu NPs treated fish when compared to control groups. However a non significant change in red blood cells (RBC) (20 and 50 µg/L Cu NPs) and mean corpuscular hemoglobin (MCH) (20 and 50 µg/L bulk Cu) were observed. The alteration in Mean Corpuscular Hemoglobin Concentration (MCHC) value was found to be non significant both in bulk and Cu NPs treated fish. The alterations of these parameters can be used as a potential indicator to examine the health of fish in aquatic ecosystem contaminated with metal and metal based nanoparticles.

Mean corpuscular hemoglobin concentration in anoxic lung disease

1961 ◽  
Vol 16 (5) ◽  
pp. 847-850 ◽  
Author(s):  
D. Verel ◽  
D. F. Kerridge
Keyword(s):  
Lung Disease ◽  
Hemoglobin Concentration ◽  
Mean Corpuscular Hemoglobin ◽  
Mean Corpuscular Hemoglobin Concentration ◽  
Corpuscular Hemoglobin ◽  
Significant Relation ◽  
Discriminate Analysis ◽  
Corpuscular Hemoglobin Concentration ◽  
Polycythemia Rubra Vera ◽  
The Mean

An analysis of patients suffering from polycythemia rubra vera, congenital heart disease, and anoxic lung disease is presented. The effect on the mean corpuscular hemoglobin concentration (MCHC) of anoxia and increased erythropoesis is compared. The results suggest that in chronic anoxic lung disease both desaturation and increased erythropoesis may play a part in lowering the MCHC. A statistically significant relation exists between the low MCHC and increased pCO2x in addition. A discriminate analysis suggests that additional factors also play a part. Submitted on December 22, 1960

scholarly journals Red blood cell counts in sows during lactation

2010 ◽  
Vol 64 (5-6) ◽  
pp. 359-365 ◽  
Author(s):  
Mirjana Joksimovic-Todorovic ◽  
Vesna Davidovic ◽  
Ljiljana Bokan
Keyword(s):  
Haemoglobin Concentration ◽  
Hemoglobin Concentration ◽  
Mean Corpuscular Hemoglobin ◽  
Lactation Period ◽  
Mean Corpuscular Hemoglobin Concentration ◽  
Corpuscular Hemoglobin ◽  
The Third ◽  
Cell Counts ◽  
Erythrocyte Sedimentation ◽  
Hematological Changes

In the course of parturition and lactation, sows are susceptible to stress and make an effort to adapt to the newly-formed situation through different endocrine and metabolic mechanisms. In addition to endocrine, biochemical changes, hematological changes also occur in the sow organism. Having these facts in mind, the objective of this work was to examine the changes in the number of erythrocytes, hemoglobin concentration, hematocrit value, hematological indexes: mean corpuscular erythrocyte volume (MCV), mean corpuscular hemoglobin (MCH) in erythrocyte and mean corpuscular hemoglobin concentration (MCHC) in erythrocytes, as well as sedimentation values during the period of lactation in sows. The experiment was performed on ten sows of the Swedish Landrace breed, from which blood was taken on the first day postpartum (1-6 h), and during the third and fourth weeks of lactation. The obtained results of hematological analyses indicated a reduced number of erythrocytes, haemoglobin concentration and hematocrit value during the lactation period. The number of erythrocytes was significantly lower at the end of lactation in comparison with the number established on the first day postpartum. The hemoglobin concentration and hematocrit value were very significantly lower at the end of lactation against the first day postpartum. The values of the hematological indexes MCV, MCH and MCHC did not differ significantly in any of the examined periods. The rate of erythrocyte sedimentation was determined 1 h and 2 h postpartum.

scholarly journals Hematological Changes Associated with Pregnancy in Domestic Sows (Suis domesticus)

2021 ◽  
Author(s):  
Simeon C. Okafor ◽  
Chinwe U. Chukwudi ◽  
Kevin C. Okanya ◽  
John I. Ihedioha
Keyword(s):  
Blood Cell ◽  
Hemoglobin Concentration ◽  
Absolute Lymphocyte Count ◽  
Mean Corpuscular Hemoglobin ◽  
Monocyte Count ◽  
Corpuscular Hemoglobin ◽  
Blood Samples ◽  
The Mean ◽  
The Absolute ◽  
Hematological Changes

Background: Pregnancy involves complex biological interaction and communication between the developing conceptus and maternal uterus, which may alter the blood cellular elements. The present investigation evaluated the hematological changes associated with pregnancy in domestic sows. Methods: Blood samples were collected by auricular venipuncture from twenty sexually mature domestic sows from four pig farms. Hematological analyses were carried out on the blood samples following standard procedures. Result: The mean packed cell volume (PCV), the red blood cell (RBC) count, hemoglobin (Hb) concentration, mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC) and absolute lymphocyte count were higher during pregnancy and lower following parturition, whereas, the mean corpuscular volume (MCV) was lower during pregnancy and declined further following parturition. The mean total white blood cell (TWBC) count and the absolute neutrophil count were higher during pregnancy and further elevated postpartum while the absolute monocyte count was lower during pregnancy and elevated postpartum. The absolute eosinophil count was significantly (p less than 0.05) lower in the pregnant sows (0.35 ± 0.13) and postpartum sows (0.21 ± 0.15) than in the non-pregnant sows (1.06 ± 0.27). These hematological alterations could assist in monitoring the physiological and health status of the dam, fetuses and pregnancy diagnosis.

scholarly journals Inaccuracy in automated measurement of hematocrit and corpuscular indices in the presence of severe hyperglycemia

Blood ◽  
1981 ◽  
Vol 57 (6) ◽  
pp. 1065-1067 ◽  
Author(s):  
JA Strauchen ◽  
W Alston ◽  
J Anderson ◽  
Z Gustafson ◽  
LF Fajardo
Keyword(s):  
Blood Glucose ◽  
Mean Corpuscular Volume ◽  
Hemoglobin Concentration ◽  
Mean Corpuscular Hemoglobin ◽  
Corpuscular Volume ◽  
Automated Measurement ◽  
Mean Corpuscular Hemoglobin Concentration ◽  
Corpuscular Hemoglobin ◽  
Hyperosmolar Glucose

Abstract Because we recently observed two patients with severe diabetic hyperglycemia and spuriously elevated electronically determined hematocrit and mean corpuscular volume (MCV), we investigated the effect of hyperglycemia on two popular automated hematology systems, the Coulter S and Ortho ELT-8. Marked hyperglycemia (blood glucose 800-- 2000 mg/dl) caused consistent overestimation of the electronically determined MCV compared to that derived from a simultaneous spun microhematocrit. The resultant overestimation and underestimation, respectively, of the derived values for hematocrit and mean corpuscular hemoglobin concentration may be clinically misleading. The mechanism of MCV elevation in hyperglycemia appears to be swelling of hyperosmolar glucose “loaded” erythrocytes when diluted into “isotonic” counting medium. This effect is readily circumvented by determination of a spun microhematocrit.

scholarly journals Impacts of Mycoplasma loads and lung lesions on immune and hematological statuses of pigs in an eight-breed cross heterogeneous population

2020 ◽  
Vol 98 (8) ◽  
Author(s):  
Qing Zhang ◽  
Jing Li ◽  
Tao Huang ◽  
Yifeng Zhang ◽  
Wenwu Xu ◽  
...  
Keyword(s):  
Blood Cell ◽  
Neutrophil Count ◽  
Lymphocyte Count ◽  
Hemoglobin Concentration ◽  
Mean Corpuscular Hemoglobin ◽  
Volume Distribution ◽  
Mean Corpuscular Hemoglobin Concentration ◽  
Corpuscular Hemoglobin ◽  
Distribution Width ◽  
Lung Lesions

Abstract Developments of pulmonary diseases, often accompanied by infections of bacteria, severely affect the meat production and welfare of pigs. This study investigated 307 pigs at age of 240 d from an eight-breed cross reared under standardized housing conditions for associations among the extent of lung lesions, bacteria load inferred from 16S rRNA sequencing of bronchoalveolar lavage fluid, as well as 57 immune cells and 25 hematological traits. We showed that the pigs under study suffered substantial and varied lung lesions, and the Mycoplasma is the most associated bacteria genera. At a false discovery rate of 0.05 (FDR &lt; 0.05), the severity of lung lesions were significantly associated with greater CD8+ to CD3+ cell ratio, neutrophil-to-lymphocyte ratio (NLR), and standard deviation of red blood cell volume distribution width (RDW-SD), and lower CD4−CD8−/CD3+, CD3+CD4−CD8−/PBMCs (peripheral blood mononuclear cells) and CD14−CD16−/PBMCs cell ratios, mean corpuscular hemoglobin concentration, lymphocyte count, and lymphocyte count percentage, reflecting an status of inflammation, immune suppression, and hypoxia of the pigs accompanying the progression of the lung lesions. The Mycoplasma abundance showed positive correlations with neutrophil count, neutrophil count percentage, NLR, monocyte count, coefficient of variation in red blood cell volume distribution width , and RDW-SD, and negative correlations with mean corpuscular hemoglobin concentration, lymphocyte count, and lymphocyte count percentage; these correlations are largely consistent with those of lung lesions, supporting the comorbidity of lung lesions and Mycoplasma infection. We also observed nonlinear associations that sharp increases in neutrophil count and neutrophil count percentage occurred only when Mycoplasma abundance raised above the population-average level. The results provide helpful insights into the changes of host immune status in response to Mycoplasma relevant lung diseases in pigs.

Sign in / Sign up

Export Citation Format

Share Document