Amino acids in muscle and kidney of potassium-deficient rats

1960 ◽  
Vol 199 (1) ◽  
pp. 39-42 ◽  
Author(s):  
Ira K. Brandt ◽  
Victor A. Matalka ◽  
Jerome T. Combs

Muscle and kidney taken from rats with potassium-deficiency alkalosis contained a higher concentration of lysine, histidine and arginine than tissue taken from pair-fed control animals. The concentration of anserine, carnosine and alpha-amino nitrogen did not differ in the two groups. Although the concentration of virtually all of the above substances varied with the length of time that the animal had been receiving the experimental diet, the relationship between the data obtained from potassium-deficient animals and from the pair-fed controls remained constant. The results suggest that a mechanism other than replacement of lost potassium as cation may bring about the increase in the basic amino acids during potassium-deficiency alkalosis and that starvation is associated with a predictable variation in some of the amino acid constituents of the tissues.

1973 ◽  
Vol 248 (7) ◽  
pp. 2387-2391 ◽  
Author(s):  
Gladys E. Deibler ◽  
Russell E. Martenson

2007 ◽  
Vol 31 (11) ◽  
pp. 1878 ◽  
Author(s):  
Yuanyuan Liu ◽  
Meigong Fan ◽  
Shuxiao Zhang ◽  
Xiaohai Sheng ◽  
Jiannian Yao

2021 ◽  
Author(s):  
Irina Gaivoronskaya ◽  
Valenitna Kolpakova

The aim of the work was to optimize the process of obtaining multicomponent protein compositions with high biological value and higher functional properties than the original vegetable protein products. Was realized studies to obtain biocomposites on the base of pea protein-oat protein and pea protein-rice protein. Developed composites were enriched with all limited amino acids. For each of the essential amino acids, the amino acid score was 100% and higher. Protein products used in these compositions are not in major allergen list, which allows to use these compositions in allergen-free products and specialized nutrition. To determine biosynthesis parameters for compositions from pea protein and various protein concentrates with the use of transglutaminase enzyme, was studied effect of concentration and exposition time on the amount of amino nitrogen released during the reaction. Decreasing of amino nitrogen in the medium indicated the occurrence of a protein synthesis reaction with the formation of new covalent bonds. Were determined optimal parameters of reaction: the hydromodule, the exposure time, the concentration of EP of the preparation, were obtained mathematical models. Studies on the functional properties of composites, the physicochemical properties of the proteins that make up their composition, and structural features will make it possible to determine the uses in the manufacture of food products based on their ability to bind fat, water, form foam, gels, and etc.


RSC Advances ◽  
2016 ◽  
Vol 6 (89) ◽  
pp. 86269-86275 ◽  
Author(s):  
Márton Bojtár ◽  
Adrien Paudics ◽  
Dóra Hessz ◽  
Miklós Kubinyi ◽  
István Bitter

Three naphthalimide derivatives were synthesized with different anchoring groups to adjust the supramolecular interactions with carboxylato-pillar[5]arene. The complexes were used as indicator displacement assays for basic amino acids and diamines.


Soft Matter ◽  
2021 ◽  
Author(s):  
Xue Wang ◽  
Xiaohuan Liu ◽  
Zhiyuan Ma ◽  
Chuanling Mu ◽  
Wen Li

A new kind of supramolecular hydrogels have been designed and synthesized via the co-assembly of basic amino acids (AAs) and heteropoly acids (HPAs) under acidic condition. The formation of gel-like...


2016 ◽  
Vol 3 (12) ◽  
pp. 1699-1704 ◽  
Author(s):  
Nicola Zanna ◽  
Andrea Merlettini ◽  
Claudia Tomasini

Nine amino acids with different chemical properties have been chosen to promote the formation of hydrogels based on the bolamphiphilic gelator A: three basic amino acids (arginine, histidine and lysine), one acidic amino acid (aspartic acid), two neutral aliphatic amino acids (alanine and serine) and three neutral aromatic amino acids (phenylalanine, tyrosine and tryptophan).


1995 ◽  
Vol 7 (6) ◽  
pp. 1491
Author(s):  
RB Krishna ◽  
J Dancis ◽  
M Levitz

Human placental chorionic villi were incubated for 30 min with [3H]lysine or [3H]arginine and the distribution ratios (intracellular:extracellular concentrations) were determined. The ratios remained unchanged when Na+ in Earle's buffered salt solution was replaced with Li+. When Na+ was replaced with choline there was a significant increase is distribution ratios (lysine 1.34 +/- 0.33 v. 3.99 +/- 0.15, arginine 1.95 +/- 0.37 v. 5.05 +/- 1.16). Leucine, a neutral amino acid with a Na(+)-independent transport system, was unaffected by choline substitution. The distribution ratio for alanine, which is Na(+)-dependent, was reduced (2.50 +/- 0.41 v. 1.45 +/- 0.20). Two other quarternary amines, acetyl-beta-methylcholine and tetraethylammonium chloride (TEA) caused similar increases in the distribution ratios of the basic amino acids. Hordenine, a tertiary amine, was less effective and there was little or no effect with ephedrine, a secondary amine. The choline effect was first observable at concentrations of 105 mM. With TEA, there was a progressive increase in distribution ratios beginning at 29 mM. Lysine efflux was measured after incubation of villi with lysine in Earle's buffer or choline buffer. Lysine was rapidly released to the fresh medium with 25% more retained in choline-exposed villi. The amines may cause alterations in the kinetics of basic amino-acid transporters or may modify other aspects of placental physiology permitting an increase retention of the basic amino acids.


1971 ◽  
Vol 17 (4) ◽  
pp. 245-266 ◽  
Author(s):  
John Atherton Young ◽  
Benedict Sol Freedman

Abstract Cushny in 1917 first remarked on the extensive amino acid reabsorption which occurs in the nephron. Although many workers since then have studied the nature and localization of the reabsorptive mechanism, progress has been slow because of the technical difficulties of micropuncture work. The bulk of filtered amino nitrogen is reabsorbed in the proximal tubule although the possibility of there being more distal reabsorptive (or secretory) sites cannot be excluded. It is also uncertain whether all segments of the proximal tubule contribute equally to the reabsorptive process. Amino acid reabsorption is an active process involving numerous illdefined steps, the first of which is binding to the brush borders. Renal amino acid transport mechanisms are of two kinds: the high-capacity low-specificity systems transport whole groups of amino acids—the acidic, basic, neutral, and imino-glycine groups—while the other, the low-capacity high-specificity systems, transport single or perhaps pairs of amino acids only.


Molecules ◽  
2019 ◽  
Vol 24 (18) ◽  
pp. 3252 ◽  
Author(s):  
Paula Ossowicz ◽  
Joanna Klebeko ◽  
Barbara Roman ◽  
Ewa Janus ◽  
Zbigniew Rozwadowski

Ionic liquids based on different l-amino acids (glycine, l-valine, l-leucine, l-isoleucine, l-histidine, l-methionine, l-tyrosine, l-tryptophan, l-arginine, and l-threonine) and different cations (tetrabutylammonium (TBA), tributylmethylammonium (tBMA), didecyldimethylammonium (DDA), (2-hydroxyethyl)trimethylammonium (choline) (Chol), alkyl(C12-C14) dimethylbenzylammonium (benzalkonium) (BA), dodecyltrimethylammonium (DDTMA), hexadecyltrimethylammonium (HDTMA), octadecyltrimethylammonium (ODTMA) and 1-ethyl-3-methylimidazolium (EMIM)) have been synthesized and characterized by NMR and FTIR. Viscosity, specific rotation, surface activity, thermal stability (TG), and phase transformations (DSC) have been determined and compared with available data. Furthermore, benzalkonium, didecyldimethylammonium, dodecyltrimethylammonium, hexadecyltrimethylammonium, and octadecyltrimethylammonium amino acid ionic liquids have been shown to exhibit surface activity. The dissolution of cellulose in amino acid ionic liquids (AAILs) composed of various cations was also investigated. Cellulose was only dissolved in EMIM salts of amino acids. In particular, the influence of the cation type on selected physicochemical and spectroscopic properties were discussed. The article is a mini review on amino acid ionic liquids.


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