Effects of diet on serum lipids of fetal, neonatal, and pregnant rabbits

The serum phospholipid, cholesterol, and triglyceride values of the fetal rabbit were determined and found to be significantly higher than similar values in the maternal host. Moreover, these fetal serum values could not be changed by altering the maternal blood lipid levels. The rise in serum cholesterol and phospholipid usually observed in the suckling rabbit could be prevented by omission of both triglyceride and cholesterol from its diet. The omission of cholesterol appeared to be most responsible for this phenomenon, because the omission solely of cholesterol from the diet of slightly older rabbits appeared capable of reducing their blood cholesterol from a level which had been elevated previously by their ingestion of cholesterol rich natural milk from lactating dams.

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A Study on Blood Lipid Levels, Nutrient Intakes, and Oxidation and Inflammation Markers of Overweight and Obese Adults according to Blood Cholesterol Levels in Korea

The Korean Journal of Food And Nutrition ◽

10.9799/ksfan.2011.24.1.001 ◽

2011 ◽

Vol 24 (1) ◽

pp. 1-11 ◽

Cited By ~ 6

Author(s):

Jee-Young Yeon ◽

Mi-Hyun Kim

Keyword(s):

Blood Lipid ◽

Blood Cholesterol ◽

Lipid Levels ◽

Inflammation Markers ◽

Nutrient Intakes ◽

Obese Adults ◽

Cholesterol Levels ◽

Blood Lipid Levels

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Characteristics and clinical significance of lipid metabolism in patients with gastrointestinal stromal tumor

Lipids in Health and Disease ◽

10.1186/s12944-021-01613-7 ◽

2022 ◽

Vol 21 (1) ◽

Author(s):

Xiaoling Liu ◽

Jun Hu ◽

Bende Liu

Keyword(s):

Clinical Significance ◽

Serum Lipids ◽

Blood Lipids ◽

High Specificity ◽

Blood Lipid ◽

Lipid Levels ◽

Specificity And Sensitivity ◽

Union Hospital ◽

S 100 ◽

Blood Lipid Levels

Abstract Background To investigate the characteristics and clinical significance of serum lipids in patients with gastrointestinal stromal tumors (GISTs). Methods The clinical and pathological data of 694 GIST patients in Liyuan hospital and Union hospital from 2012 to 2016 were retrospectively analyzed. Blood lipid levels in patients with varying degrees of risk were compared. Results The findings showed that LDL-C, HDL-C, and CHOL increased significantly in women, and CD34 positive. In patients with tumors size less than 5 cm in diameter, TG, HDL-C, and CHOL were significantly higher. TG levels were significantly higher in DOG-1 (a marker and has a high specificity and sensitivity in the diagnosis of GIST) positive patients than in DOG-1 negative patients (P < 0.05). S-100 positive patients had lower HDL-C levels than S-100 negative patients (P < 0.05). Lipids indexes were found to be correlated with GIST risk stratification and tumor site (P < 0.05). TG/HDL-C was were significantly different among patients with GIST in different locations (P < 0.05). Conclusion The clinical and pathological characteristics of the patients with GIST are closely related to the level of blood lipids. To a certain extent, information about level of blood lipids can be helpful for distinguishing benign and malignant GIST.

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Association between maternal serum lipids during late pregnancy and adverse birth outcomes

10.21203/rs.3.rs-52160/v1 ◽

2020 ◽

Author(s):

Meng-Yi Dai ◽

Lu-Lin Wang ◽

Yun-Tao Wu ◽

Huan Li ◽

Jian-Hong Xia ◽

...

Keyword(s):

Birth Outcomes ◽

Linear Trend ◽

Late Pregnancy ◽

Blood Lipid ◽

Maternal Blood ◽

Adverse Birth Outcomes ◽

Lipid Levels ◽

Increased Risk ◽

Unit Increase ◽

Blood Lipid Levels

Abstract Background: Adverse birth outcomes have short- and long-term impacts on maternal and child health. Maternal dyslipidemia during late pregnancy has been found to be associated with increased risk of adverse birth outcomes. However, similar evidence on association between maternal blood lipid levels and adverse birth outcomes is limited in China.Methods: The data were extracted from Guangdong Women and Children Hospital Information System from September 2014 to March 2018. A total of 3951 mother-newborn pairs were included in our study. Logistic regression model and linear trend analysis were conducted to analyze the correlation between maternal blood lipid levels and adverse birth outcomes after controlling potential confounders including gestational age, pre-pregnancy body mass index, fetal sex, and parity. Results: Among the 3951 subjects, the rates of macrosomia, large-for-gestational age (LGA), low birth weight infants (LBW), and preterm birth were 3.9% (154/3951), 8.5% (334/3951), 9.5% (377/3951), and 9.8% (388/3951), respectively. LDL was a risk factor for preterm birth (OR: 1.20; 95% CI: 1.08-1.34) while HDL was a protective factor (OR: 0.73; 95% CI: 0.55-0.96) after adjusting for covariates. As every unit increase in TG, the risk of macrosomia and LGA increased by 25% (adjusted OR: 1.25; 95% CI: 1.12-1.38) and 16% (adjusted OR: 1.16; 95% CI: 1.07-1.26), respectively. However, every unit increase in HDL concentration was associated with decreased risk for LGA (adjusted OR: 0.60; 95% CI: 0.44-0.81) and macrosomia (adjusted OR: 0.64; 95% CI: 0.41-0.99). High LDL concentrations were associated with a decreased risk of macrosomia (adjusted OR: 0.82; 95% CI: 0.68-0.99) and LGA (adjusted OR: 0.86; 95% CI: 0.76-0.98) but an increased risk of LBW (adjusted OR: 1.16; 95% CI: 1.04-1.30). The results of linear trend analysis were similar to those of logistic regression model.Conclusions: Maternal dyslipidemia during the third trimester is closely related to adverse birth outcomes. Monitoring and managing maternal blood lipid levels in an appropriate range may help to reduce the burden of adverse birth outcomes.

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High maternal blood lipid levels during early pregnancy are associated with increased risk of congenital heart disease in offspring

Acta Obstetricia Et Gynecologica Scandinavica ◽

10.1111/aogs.14225 ◽

2021 ◽

Author(s):

Li Cao ◽

Yan Du ◽

Mo Zhang ◽

Feng Wang ◽

Jian‐Yuan Zhao ◽

...

Keyword(s):

Congenital Heart Disease ◽

Heart Disease ◽

Early Pregnancy ◽

Congenital Heart ◽

Blood Lipid ◽

Maternal Blood ◽

Lipid Levels ◽

Increased Risk ◽

Blood Lipid Levels

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The Effect of Knowledge, Behaviors, and Attitudes Towards Dietary Fatty Acids on Blood Lipid Levels

The Boller Review ◽

10.18776/tcu/br/4/110 ◽

2019 ◽

Vol 4 ◽

Author(s):

Amber Deckard

Keyword(s):

Fatty Acids ◽

Blood Lipid ◽

Strong Relationship ◽

Dietary Fatty Acids ◽

Blood Cholesterol ◽

Food Sources ◽

Lipid Levels ◽

Animal Fat ◽

Lipid Panel ◽

Blood Lipid Levels

Research has shown a strong relationship between dietary fatty acids (FAs) and their impact on blood cholesterol. Few studies have examined knowledge, behaviors and attitudes (KBA) towards dietary FAs impact blood lipid levels. The objective of this project was to determine: 1) KBA of FAs using the modified General Nutrition Knowledge Questionnaire (GNKQ); and 2) correlations between anthropometric data, GNKQ responses, and blood lipid levels. This study utilized across-sectional research design in which 104 women ages 18-40 consented and completed the modified GNKQ via Qualtrics®. The GNKQ consisted of 70 questions. Additionally, a subset of nine women also were instructed to fast for 12-15 hours prior to testing at the Obesity Prevention Laboratory at TCU. Height (cm), weight (kg), BMI (kg/m2), waist-to-hip ratio were recorded. Next, a fasting blood sample (5mL) was obtained. The blood samples were sent to AnyLabTestNow® (Fort Worth, Texas) for a lipid panel. Results were then analyzed via IBM SPSS® (Statistics Version 25.0. Armonk, NY). Significance was set at p<0.05.More than 80% of participants were aware of saturated, monounsaturated, and polyunsaturated FAs, but only 33.3% were able to identify their proper food sources. Of the 34 knowledge-based questions, approximately 1.9% demonstrated poor knowledge (answered 0-11 questions correctly), 54.3% moderate knowledge (12-23 questions correctly), and 43.8% strong knowledge (24-34 questions correctly). For the subset, there was a significant negative correlation between LDL and participants who self-reported consuming less or maintaining current consumption of animal fat (r= -0.725, p=0.027). There were no other significant correlations between KBA and lipid panel results. Despite self-reported awareness, participants lack knowledge of dietary FAs. The subset results showed strong correlation between LDL and consumption of animal fat representing the relationship between diet and lipid levels. Overall, more research should is needed with a larger sample.

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