scholarly journals The Effect of Knowledge, Behaviors, and Attitudes Towards Dietary Fatty Acids on Blood Lipid Levels

2019 ◽  
Vol 4 ◽  
Author(s):  
Amber Deckard
Keyword(s):  
Fatty Acids ◽  
Blood Lipid ◽  
Strong Relationship ◽  
Dietary Fatty Acids ◽  
Blood Cholesterol ◽  
Food Sources ◽  
Lipid Levels ◽  
Animal Fat ◽  
Lipid Panel ◽  
Blood Lipid Levels

Research has shown a strong relationship between dietary fatty acids (FAs) and their impact on blood cholesterol. Few studies have examined knowledge, behaviors and attitudes (KBA) towards dietary FAs impact blood lipid levels. The objective of this project was to determine: 1) KBA of FAs using the modified General Nutrition Knowledge Questionnaire (GNKQ); and 2) correlations between anthropometric data, GNKQ responses, and blood lipid levels. This study utilized across-sectional research design in which 104 women ages 18-40 consented and completed the modified GNKQ via Qualtrics®. The GNKQ consisted of 70 questions. Additionally, a subset of nine women also were instructed to fast for 12-15 hours prior to testing at the Obesity Prevention Laboratory at TCU. Height (cm), weight (kg), BMI (kg/m2), waist-to-hip ratio were recorded. Next, a fasting blood sample (5mL) was obtained. The blood samples were sent to AnyLabTestNow® (Fort Worth, Texas) for a lipid panel. Results were then analyzed via IBM SPSS® (Statistics Version 25.0. Armonk, NY). Significance was set at p<0.05.More than 80% of participants were aware of saturated, monounsaturated, and polyunsaturated FAs, but only 33.3% were able to identify their proper food sources. Of the 34 knowledge-based questions, approximately 1.9% demonstrated poor knowledge (answered 0-11 questions correctly), 54.3% moderate knowledge (12-23 questions correctly), and 43.8% strong knowledge (24-34 questions correctly). For the subset, there was a significant negative correlation between LDL and participants who self-reported consuming less or maintaining current consumption of animal fat (r= -0.725, p=0.027). There were no other significant correlations between KBA and lipid panel results.  Despite self-reported awareness, participants lack knowledge of dietary FAs. The subset results showed strong correlation between LDL and consumption of animal fat representing the relationship between diet and lipid levels. Overall, more research should is needed with a larger sample.

scholarly journals Nutrigenetic Contributions to Dyslipidemia: A Focus on Physiologically Relevant Pathways of Lipid and Lipoprotein Metabolism

Nutrients ◽  
2018 ◽  
Vol 10 (10) ◽  
pp. 1404 ◽  
Author(s):  
Bridget Hannon ◽  
Naiman Khan ◽  
Margarita Teran-Garcia
Keyword(s):  
Lipoprotein Metabolism ◽  
Blood Lipid ◽  
Dietary Fatty Acids ◽  
Lipid Levels ◽  
Negative Effects ◽  
Major Predictor ◽  
Genetic And Environmental Factors ◽  
Elevated Lipid ◽  
Cvd Mortality ◽  
Blood Lipid Levels

Cardiovascular disease (CVD) remains the number one cause of death worldwide, and dyslipidemia is a major predictor of CVD mortality. Elevated lipid concentrations are the result of multiple genetic and environmental factors. Over 150 genetic loci have been associated with blood lipid levels. However, not all variants are present in pathways relevant to the pathophysiology of dyslipidemia. The study of these physiologically relevant variants can provide mechanistic understanding of dyslipidemia and identify potential novel therapeutic targets. Additionally, dietary fatty acids have been evidenced to exert both positive and negative effects on lipid profiles. The metabolism of both dietary and endogenously synthesized lipids can be affected by individual genetic variation to produce elevated lipid concentrations. This review will explore the genetic, dietary, and nutrigenetic contributions to dyslipidemia.

Effects of diet on serum lipids of fetal, neonatal, and pregnant rabbits

1961 ◽  
Vol 201 (4) ◽  
pp. 611-616 ◽  
Author(s):  
Meyer Friedman ◽  
Sanford O. Byers
Keyword(s):  
Serum Lipids ◽  
Blood Lipid ◽  
Maternal Blood ◽  
Blood Cholesterol ◽  
Lipid Levels ◽  
Serum Phospholipid ◽  
Fetal Serum ◽  
Natural Milk ◽  
Suckling Rabbit ◽  
Blood Lipid Levels

The serum phospholipid, cholesterol, and triglyceride values of the fetal rabbit were determined and found to be significantly higher than similar values in the maternal host. Moreover, these fetal serum values could not be changed by altering the maternal blood lipid levels. The rise in serum cholesterol and phospholipid usually observed in the suckling rabbit could be prevented by omission of both triglyceride and cholesterol from its diet. The omission of cholesterol appeared to be most responsible for this phenomenon, because the omission solely of cholesterol from the diet of slightly older rabbits appeared capable of reducing their blood cholesterol from a level which had been elevated previously by their ingestion of cholesterol rich natural milk from lactating dams.

scholarly journals Lipid-Associated Variants near ANGPTL3 and LPL Show Parent-of-Origin Specific Effects on Blood Lipid Levels and Obesity

Genes ◽  
2021 ◽  
Vol 13 (1) ◽  
pp. 91
Author(s):  
Anna Lessmark ◽  
Gad Hatem ◽  
Györgyi Kovacs ◽  
Marta Vitai ◽  
Emma Ahlqvist ◽  
...  
Keyword(s):  
Complex Traits ◽  
Plasma Lipid ◽  
Blood Lipid ◽  
Strong Relationship ◽  
Parental Origin ◽  
Parental Effects ◽  
Lipid Levels ◽  
Specific Effects ◽  
Parent Of Origin ◽  
Blood Lipid Levels

Parent-of-origin effects (POE) and sex-specific parental effects have been reported for plasma lipid levels, and a strong relationship exists between dyslipidemia and obesity. We aim to explore whether genetic variants previously reported to have an association to lipid traits also show POE on blood lipid levels and obesity. Families from the Botnia cohort and the Hungarian Transdanubian Biobank (HTB) were genotyped for 12 SNPs, parental origin of alleles were inferred, and generalized estimating equations were modeled to assess parental-specific associations with lipid traits and obesity. POE were observed for the variants at the TMEM57, DOCK7/ANGPTL3, LPL, and APOA on lipid traits, the latter replicated in HTB. Sex-specific parental effects were also observed; variants at ANGPTL3/DOCK7 showed POE on lipid traits and obesity in daughters only, while those at LPL and TMEM57 showed POE on lipid traits in sons. Variants at LPL and DOCK7/ANGPTL3 showed POE on obesity-related traits in Botnia and HTB, and POE effects on obesity were seen to a higher degree in daughters. This highlights the need to include analysis of POEs in genetic studies of complex traits.

Blood Lipid Levels in a Rural Male Population

2001 ◽  
Vol 8 (3) ◽  
pp. 165-174 ◽  
Author(s):  
A. Thelin ◽  
E.-L. Stiernstrom ◽  
S. Holmberg
Keyword(s):  
Blood Lipid ◽  
Lipid Levels ◽  
Male Population ◽  
Blood Lipid Levels
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