Impact of Diffusion, Ultrafiltration, and Posture on Total Body Electrical Resistance in Patients on Hemodialysis

Author(s):  
Jantine Schotman ◽  
Marcel van Borren ◽  
Jack Wetzels ◽  
Heinrich Kloke ◽  
Louis Reichert ◽  
...  

Background Monitoring of hydration in patients on hemodialysis (HD) by currently available bioelectrical impedance analysis (BIA) methods is hampered by limited accuracy. This may be caused by changes in total body electrical resistance (TBER) that are induced by processes other than ultrafiltration (UF). To identify these sources of error we examined the impact of UF, diffusion, and postural change (PC), separately. Methods Extracellular TBER (TBERe) was measured by bioimpedance spectroscopy every 30 min in 23 patients on HD, for 2 hours during diffusion-only (DO), followed by 2 hours UF-only (UFO). The impact of PC from upright to semi-recumbent position was assessed by a 2-hour TBERe measurement on the day after HD. Results TBERe increased by 23.5 ± 12.4 Ω (P < 0.001) during DO and by 40.0 ± 16.2 Ω (P < 0.001) during UFO. PC, evaluated on a separate day, was associated with an increase in TBERe of 27.6 ± 26.0 Ω (P < 0.001). TBERe changes during DO were mainly attributed to PC and to a lesser extent to electrolyte exchange. Extrapolation of the data to a conventional 4-hour HD session indicates that about 32% of the total increase in TBERe is not related to UF. Conclusions A significant part of the increase in TBER during HD is not related to UF but can be attributed to other processes such as the effects of PC and diffusion-related electrolyte exchange. These factors have to be taken into account when TBER-guided UF is considered.

2000 ◽  
Vol 23 (3) ◽  
pp. 168-172 ◽  
Author(s):  
B. Oe ◽  
C.W.H. De Fijter ◽  
A.B.M. Geers ◽  
P.F. Vos ◽  
A.J.M. Donker ◽  
...  

Several equations are available to derive lean body mass (LBM) from bioelectrical impedance analysis (BIA). The purpose of this study was to investigate in dialysis patients the impact of the equation used on the outcome of LBM assessment. To avoid dyshydration as a confounder, vena cava diameter measurement was used to assess normohydration in the 21 patients studied. Five equations were compared. In a previously published study to assess total body water using antipyrine as a gold standard, Deurenberg's formula was advocated to be used in the estimation of LBM by BIA. Therefore, this formula was used as a basis for comparison with the other four equations. One equation gave results comparable to those obtained by Deurenberg's formula. Despite high correlations and agreement according to Bland and Altman analysis, the other three equations showed a significant difference with Deurenberg-derived LBM. Thus, the equation used has a major impact on the outcome of LBM estimations. (Int J Artif Organs 2000; 23: 168–72)


2020 ◽  
pp. 1-6
Author(s):  
Gabriela Salazar ◽  
Barbara Leyton ◽  
Carolina Aguirre ◽  
Alyerina Anziani ◽  
Gerardo Weisstaub ◽  
...  

Abstract Assessing children’s growth adequately is important due to the necessary prevention of adequate body composition, especially at pre-pubertal age. Simpler measurements such as anthropometry or bioimpedance, using equations validated in Caucasian children, have been demonstrated to overestimate or underestimate fat mass percentage (FM%) or fat-free mass (FFM) in Chilean children. In a sample of 424 children (198 boys and 226 girls) of 7–9 years old, the three component (3C) model was assessed, where total body water was determined by 2H dilution and body volume by air displacement plethysmography, in order to design and validate anthropometry and bioimpedance equations. The FM (%) equation specific for Chilean children was validated as (1·743 × BMI z-score) + (0·727 × triceps skinfold) + (0·385 × biceps skinfold) + 15·985, against the 3C model (R2 0·79). The new FFM equation (kg) generated was (log FFM = (0·018 × age) + (0·047 × sex) + (0·006 × weight) + (0·027 × resistance) + 2·071), with an R2 0·93 (female = 1 and male = 2). The Bland–Altman analysis shows a mean difference of 0·27 (sd 3·5) for the FM% in the whole group as well as 0·004 (sd 0·9) kg is the mean difference for the bioelectrical impedance analysis (BIA) FFM (kg) equation. The new equations for FM (%) and FFM (kg) in Chilean children will provide a simple and valid tool for the assessment of body composition in cohort studies or to assess the impact of nutritional programmes or public policies.


2016 ◽  
Vol 2016 ◽  
pp. 1-9 ◽  
Author(s):  
Dong Guo ◽  
Jianfeng Gong ◽  
Lei Cao ◽  
Yao Wei ◽  
Zhen Guo ◽  
...  

Aim. The study aimed to investigate the impact of laparoscopic surgery and open surgery on postoperative edema in Crohn’s disease.Methods. Patients who required enterectomy were divided into open group (Group O) and laparoscopic group (Group L). Edema was measured using bioelectrical impedance analysis preoperatively (PRE) and on postoperative day 3 (POD3) and postoperative day 5 (POD5). The postoperative edema was divided intoslight edemaandedemaby an edema index, defined as the ratio of total extracellular water to total body water.Results. Patients who underwent laparoscopic surgery had better clinical outcomes and lower levels of inflammatory and stress markers. A total of 31 patients (26.05%) developedslight edemaand 53 patients (44.54%) developededemaon POD3. More patients developed postoperative edema in Group O than in Group L on POD3 (p=0.006). The value of the edema index of Group O was higher than that of Group L on POD3 and POD5 (0.402±0.010versus0.397±0.008,p=0.001;0.401±0.009versus0.395±0.007,p=0.039, resp.).Conclusions. Compared with open surgery, laparoscopic surgery can reduce postoperative edema, which may contribute to the better outcomes of laparoscopic surgery over open surgery.


Author(s):  
Carly Welch ◽  
Zeinab Majid ◽  
Isabelle Andrews ◽  
Zaki Hassan-Smith ◽  
Vicky Kamwa ◽  
...  

Abstract Background Ultrasonography is an emerging non-invasive bedside tool for muscle quantity/quality assessment; Bioelectrical Impedance Analysis (BIA) is an alternative non-invasive bedside measure of body composition, recommended for evaluation of sarcopenia in clinical practice. We set out to assess impact of position and exercise upon measures towards protocol standardisation. Methods Healthy volunteers aged 18–35 were recruited. Bilateral Anterior Thigh Thickness (BATT; rectus femoris and vastus intermedius), BATT: Subcutaneous Ratio (BATT:SCR), and rectus femoris echogenicity were measured using ultrasound and BIA was performed; 1) lying with upper body at 45° (Reclined), 2) lying fully supine at 180o (Supine), 3) sat in a chair with upper body at 90o (Sitting), and 4) after exercise Reclined. Variability of Skeletal Muscle Mass (SMM) by two different equations from BIA (SMM-Janssen, SMM-Sergi), phase angle, fat percentage, and total body (TBW), extracellular (ECW), and intracellular water (ICW) were assessed. Results Forty-four participants (52% female; mean 25.7 years-old (SD 5.0)) were recruited. BATT increased from Reclined to Sitting (+ 1.45 cm, 1.27–1.63), and after exercise (+ 0.51, 0.29–0.73). Echogenicity reduced from Reclined to Sitting (− 2.1, − 3.9 – -0.26). SMM-Sergi declined from Reclined to Supine (− 0.65 kg, − 1.08 – − 0.23) and after exercise (− 0.70 kg, − 1.27 – -0.14). ECW increased from Reclined to Sitting (+ 1.19 L, 0.04–2.35). There were no other statistically significant changes. Conclusion Standardisation of protocols is especially important for assessment of muscle quantity by ultrasonography; BIA measurements may also vary dependent on the equations used. Where possible, participants should be rested prior to muscle ultrasonography and BIA, and flexion of the knees should be avoided.


1997 ◽  
Vol 20 (7) ◽  
pp. 371-374 ◽  
Author(s):  
B. Oe ◽  
W.M. De Fijter ◽  
C.W.H. De Fijter ◽  
B. Straver ◽  
P.L. Oe ◽  
...  

The purpose of the present study was to investigate whether total body bioelectrical impedance analysis (BIA) could be appropriate to assess normohydration (i.e. dry weight) in hemodialysis patients. This study is warranted, because the simultaneous assessment of both hydration and nutritional status by BIA requires the presence of a situation of normohydration in order to guarantee valid conclusions about the nutritional analysis. Segmental bioelectrical impedance was performed to classify patients according to their hydration status. BIA measurements revealed significant differences in TBW, ECW and ICW/ECW between three hydration subgroups (under-, normo-, and overhydration), whereas ICW was similar. Therefore, TBW, ECW and ICW/ECW appear appropriate variables to assess hydration status in patients on hemodialysis. Hemodialysis diminished ECW significantly, whereas ICW did not change, suggesting that a decrease of ECW explains the fluid loss during hemodialysis.


Medicina ◽  
2012 ◽  
Vol 48 (4) ◽  
pp. 29 ◽  
Author(s):  
Sermin Sengun ◽  
Atilla Uslu ◽  
Salih Aydin

Background and Objective. The level of dehydration has been known to be a predisposing factor for the development of decompression sickness in divers. The aim of this study was to determine the level of dehydration in divers who dove with heliox and to determine whether the source of this dehydration was intracellular and/or extracellular by means of multifrequency bioelectrical impedance analysis (MF-BIA). Material and Methods. Eleven male professional divers were enrolled in the study. In order to determine the level of dehydration, MF-BIA was carried out (at 5, 50, and 100 kHz) and capillary hematocrit (Hct) was measured two times: one before diving and the other after leaving the pressure room. Results. When prediving and postdiving parameters were compared, significant increases in the resistance at 5 kHz (P<0.001), 50 kHz, (P<0.001), and 100 kHz (P<0.01) and Hct (P<0.01) were observed after the diving. Similarly, a statistically significant fluid shift was found: total body water, –1.30 L (P<0.001), extracellular water, –0.85 L (P<0.001); and intracellular water, –0.45 L (P=0.011). Conclusions. Our results showed that mild dehydration occurred both in the intracellular and extracellular compartments in divers after deep diving. This study also indicates that MF-BIA could be a reliable new method for determining the dehydration status in divers.


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