scholarly journals Reference Values of Pulmonary Function Tests for Canadian Caucasians

2004 ◽  
Vol 11 (6) ◽  
pp. 414-424 ◽  
Author(s):  
Carlos Gutierrez ◽  
R Heberto Ghezzo ◽  
Raja T Abboud ◽  
Manuel G Cosio ◽  
John R Dill ◽  
...  
Keyword(s):  
Pulmonary Function ◽  
Pulmonary Function Tests ◽  
Cross Sectional Study ◽  
National Standard ◽  
Test Results ◽  
Cross Sectional ◽  
Pooled Data ◽  
Function Tests ◽  
Function Test ◽  
Good Agreement

A multicentre, cross-sectional study was carried out in six centres across Canada to establish a national standard for pulmonary function tests using healthy, lifetime nonsmokers, with each centre aiming to test 10 men and 10 women from each decade from 20 to 80 years of age. Data from each centre were used to derive prediction equations for each centre, and pooled data from all centres (total: 327 women and 300 men) were used to derive Canadian predicted equations. The predictive models were compared with three widely used published models for selected tests. It was found that, in general, the equations modelled for each centre could be replaced by the models obtained when pooling all data (Canadian model). Comparisons with the published references showed good agreement and similar slopes for most tests. The results suggest that pulmonary function test results obtained from different centres in Canada were comparable and that standards currently used remain valid for Canadian Caucasians.

scholarly journals A Cross-Sectional Study of Nemaline Myopathy

Neurology ◽  
2021 ◽  
pp. 10.1212/WNL.0000000000011458
Author(s):  
Kimberly Amburgey ◽  
Meryl Acker ◽  
Samia Saeed ◽  
Reshma Amin ◽  
Alan H. Beggs ◽  
...  
Keyword(s):  
Pulmonary Function ◽  
Outcome Measures ◽  
Pulmonary Function Tests ◽  
Severe Disease ◽  
Nemaline Myopathy ◽  
Cross Sectional Study ◽  
Longitudinal Assessment ◽  
Sectional Study ◽  
Cross Sectional ◽  
Function Tests

Objective:Nemaline myopathy (NM) is a rare neuromuscular condition with clinical and genetic heterogeneity. To establish disease natural history, we performed a cross-sectional study of NM, complemented by longitudinal assessment and exploration of pilot outcome measures.Methods:Fifty-seven individuals with NM were recruited at two family workshops, including 16 examined at both time points. Subjects were evaluated by clinical history and physical examination. Functional outcome measures included the Motor Function Measure (MFM), pulmonary function tests (PFTs), myometry, goniometry, and bulbar assessments.Results:The most common clinical classification was “typical congenital” (54%), whereas 42% had more severe presentations. 58% of individuals needed mechanical support, with 26% requiring wheelchair, tracheostomy, and feeding tube. The MFM scale was performed in 44/57 participants and showed reduced scores in most with little floor/ceiling effect. Of the 27 individuals completing PFTs, abnormal values were observed in 65%. Lastly, bulbar function was abnormal in all patients examined, as determined using a novel outcome measure. Genotypes included mutations in ACTA1 (18), NEB (20), and TPM2 (2). Seventeen individuals were genetically unresolved. Patients with pathogenic ACTA1 and NEB variants were largely similar in clinical phenotype. Patients without genetic resolution had more severe disease.Conclusion:In all, we present a comprehensive cross-sectional study of NM. Our data identify significant disabilities and support a relatively stable disease course. We identify a need for further diagnostic investigation for the genetically unresolved group. Lastly, MFM, pulmonary function tests, and the slurp test were identified as promising outcome measures for future clinical trials.

scholarly journals Pulmonary Function Tests and Their Associated Factors in HIV-infected Patients at Jimma Medical Center; Ethiopia: A Comparative Cross-Sectional Study

2021 ◽  
Author(s):  
Muluken Teshome ◽  
Teshome Gobena ◽  
Misganaw Asmamaw ◽  
Elias Mulat
Keyword(s):  
Pulmonary Function ◽  
Medical Center ◽  
Pulmonary Function Tests ◽  
Cross Sectional Study ◽  
Hiv Positive ◽  
Duration Of Treatment ◽  
Cross Sectional ◽  
Retroviral Infection ◽  
Function Test ◽  
History Of

Abstract BackgroundHIV-infected persons have a greater risk of developing respiratory disorders. Poor socio-economic status, High viral load, low CD4 counts, and anti-retroviral therapy are linked with the problems. Despite its high prevalence the association between retroviral infection and pulmonary function status as well as their associated factors has not yet well established in resource-scarce countries in general and study setting in particularMethodsA comparative cross-sectional study was conducted from September 24 to October 15 of 2020 at Jimma Medical Center among HIV-positive patients and matched control group. Data were collected using a pretested structured questionnaire administered via face-to-face interview. The collected data included Socio-demographic, respiratory, retroviral infection, and substance use related. Pulmonary function tests were also conducted using SP10 spirometer. Collected data were entered and analyzed using SPSS version 26. Independent t-test and multiple linear regressions were carried out to identify factors independently associated with the pulmonary function status of the study participants while controlling for potential confounders.ResultsOne hundred ninety two HIV-positive patients and matched control individuals participated in the study. A mean pulmonary function test parameters among HIV-infected participants were FVC (l) (2.957±0.792, p0.006), FEV (l) (2.289±0.593, p<0.001), and PEFR (l) (4.258±2.039, p<0.001) with a significant declined in the group. Respiratory symptom, history of pulmonary TB, duration of living with RVI, duration of treatment, and current CD4 cell count were significant predictors of pulmonary function test indices(p<0.05) in HIV infected respondents.ConclusionA significant reduction in mean pulmonary function parameters were observed among HIV-positive participants in comparison to non-RVI participants. A strong association was observed between pulmonary function status of HIV-infected patients and current CD4 count, duration of living with RVI, duration of treatment, and history of PTB. Therefore, due consideration in screening, diagnosing, and managing noninfectious lung diseases should be given by health professionals while treating HIV-infected patients.

scholarly journals Pulmonary Densitovolumetry Using Computed Tomography in Patients with Nontuberculous Mycobacteria: Correlation with Pulmonary Function Tests

2019 ◽  
Vol 2019 ◽  
pp. 1-9
Author(s):  
Patricia Gomes Cytrangulo De Marca ◽  
Telma Goldenberg ◽  
Fernanda Carvalho Queiroz Mello ◽  
Alysson Roncally Silva Carvalho ◽  
Alan Ranieri Medeiros Guimarães ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Pulmonary Function ◽  
Pulmonary Function Tests ◽  
Lung Parenchyma ◽  
Cross Sectional Study ◽  
Detailed Knowledge ◽  
Lung Mass ◽  
Cross Sectional ◽  
Total Lung Volume ◽  
Function Tests

Background. Since nontuberculous mycobacterial pulmonary disease (NTM-PD) is a condition with increasing morbidity, a more detailed knowledge of radiological aspects and pulmonary function plays a relevant role in the diagnosis and appropriate therapeutic management of these patients. Objectives. The purpose of this study was to evaluate changes in lung parenchyma through computed tomography (CT) densitometry and, secondarily, to analyze its correlation with pulmonary function testing (PFT) in patients with NTM-PD. Methods. This is a cross-sectional study in which 31 patients with NTM-PD and 27 controls matched by sex, age, and body mass index underwent CT pulmonary densitovolumetry and pulmonary function tests including spirometry and body plethysmograph. Results. Based on the total lung volume (TLV) and total lung mass (TLM) measurements, the cumulative mass ratios were calculated for 3% (M3), 15% (M15), 85% (M85), and 97% (M97) of the TLV. We also calculated the complement, which is represented by TLM (100%) minus the mass of 15% (C85) or 3% (C97) of the TLV. Patients with NTM-PD presented lower values ​​of M3 and M15 than controls, with greater significant differences in the apical third and middle third measurements. Compared to controls, patients with NTM-PD showed higher values ​​of C85 and C97, although significant differences were observed only in the basal third measurements. There were negative correlations of total lung capacity with M3 and M15 in the middle third and apical third measurements. There were positive correlations of residual volume and airway resistance with M3 at the apical third measurement. Conclusions. Patients with NTM-PD show reduced lung mass and increased lung mass in the apical and basal regions of the lungs, respectively. Furthermore, there is a relationship between lung mass measurements and pulmonary function parameters.

scholarly journals Pulmonary function tests of mongoloid and non mongoloid group of Dharan

2019 ◽  
Vol 9 (1) ◽  
pp. 32-35
Author(s):  
Nisha Ghimire ◽  
Kopila Agrawal ◽  
Santosh Deo ◽  
Lok Bandhu Chaudhary ◽  
Bishnu Hari Paudel
Keyword(s):  
Pulmonary Function ◽  
Surface Area ◽  
Pulmonary Function Tests ◽  
Sampling Technique ◽  
Cross Sectional Study ◽  
Prediction Equations ◽  
European Respiratory Society ◽  
Cross Sectional ◽  
Normal Reference ◽  
Function Tests

Background: Ethnicity is seen to effect normal reference values and pre­diction equations of pulmonary function tests (PFTs). The normal refer­ence of PFTs among mongoloid and non mongoloid group of Dharan is not available. The aim of the study was to find out the normal reference val­ues of two groups in Dharan and also to find out the correlation of height, weight and body surface area with different PFT parameters. Methods: This cross-sectional study was conducted among 250 (125 mongoloids and 125 non mongoloids) healthy male subjects. Convenient sampling technique was done. Every 5th patient attendant who was per­manent resident of Dharan coming to clinical Physiology lab was selected as subject in each group. Portable PFT machine (CHESTOGRAPH, HI-101 Spirometry system) was used for measurement of our test. The test was conducted according to European Respiratory Society (ERS)/American Thoracic Society (ATS criteria. Results: Independent sample t-test was used to compare means be­tween two groups. There was significantly more height (165.30±8.21 vs 161.43±7.35), p <.05], weight [(59.29±11.64 vs 55.32±10.75), p<.05andbody surface area [(1.64±.172Vs1.57±.149), p<.05], in the non-mongoloid group compared to mongoloid group. PFT param­eters were also higher in non-mongoloid group VC [(3.3982±.70725 Vs3.0982±.78832) p<.05], FVC [(3.2798±.74312 Vs 2.988±.81970), p <.05], and FEV1 [(3.0668±.72044 Vs 2.7861±.83061) p<.05]. The prediction equations were also calculated for both groups. Conclusions: There was difference in PFT parameters between two groups. Prediction equations were also different in both groups.

“A COMPARATIVE STUDY OF LUNG FUNCTION TESTS IN SWIMMERS AND NORMAL INDIVIDUALS”

2021 ◽  
pp. 31-33
Author(s):  
Shaik Auliya Parveen ◽  
P. Nanda Kumar ◽  
B.V.K. Vijayalakshmi
Keyword(s):  
Pulmonary Function ◽  
Pulmonary Function Tests ◽  
Total Sample ◽  
Cross Sectional Study ◽  
The Body ◽  
Swimming Pool ◽  
Upper Body ◽  
Cross Sectional ◽  
Function Tests ◽  
Disease Hospital

Introduction: Our human body is an amazing machine, in which perfectly coordinated events will occur simultaneously. Swimming is a sport which is suitable for people of many different ages, and tness levels. Regular swimming produces many changes in the body. It benets the upper body, torso and legs together and it will improve general strength, lung capacity, stamina and cardiovascular tness. Swimming is an aerobic exercise and it has a signicant effect on respiratory functions that helps the lungs to use oxygen efciently. Aim and objectives:Aim of the present study is to compare the Pulmonary Function Tests of swimmers and non-swimmers and to know whether swimming brings any changes in the pulmonary function tests .Materials and Methods: The present study is a cross sectional study .The total sample size is 100. Swimmers (subjects) are 50 and non-swimmers (controls) are 50 in number. Swimmers are selected from N.T.R.Stadium Swimming Pool, Guntur and Guntur Club Swimming pool, Guntur. Hundred subjects were screened for the study and 50 were selected as subjects. The Pulmonary Function Tests was conducted in the Infectious Disease Hospital, Guntur. Summary and Conclusion: In our study, there is a signicant increase in pulmonary function tests in swimmers compared to non – swimmers.

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