scholarly journals Test-Retest Reliability of fMRI During Nonverbal Semantic Decisions in Moderate-Severe Nonfluent Aphasia Patients

2004 ◽  
Vol 15 (3-4) ◽  
pp. 87-97 ◽  
Author(s):  
Jacquie Kurland ◽  
Margaret A. Naeser ◽  
Errol H. Baker ◽  
Karl Doron ◽  
Paula I. Martin ◽  
...  

Cortical reorganization in poststroke aphasia is not well understood. Few studies have investigated neural mechanisms underlying language recovery in severe aphasia patients, who are typically viewed as having a poor prognosis for language recovery. Although test-retest reliability is routinely demonstrated during collection of language data in single-subject aphasia research, this is rarely examined in fMRI studies investigating the underlying neural mechanisms in aphasia recovery.The purpose of this study was to acquire fMRI test-retest data examining semantic decisions both within and between two aphasia patients. Functional MRI was utilized to image individuals with chronic, moderate-severe nonfluent aphasia during nonverbal, yes/no button-box semantic judgments of iconic sentences presented in the Computer-assisted Visual Communication (C-ViC) program. We investigated the critical issue of intra-subject reliability by exploring similarities and differences in regions of activation during participants' performance of identical tasks twice on the same day. Each participant demonstrated high intra-subject reliability, with response decrements typical of task familiarity. Differences between participants included greater left hemisphere perilesional activation in the individual with better response to C-ViC training. This study provides fMRI reliability in chronic nonfluent aphasia, and adds to evidence supporting differences in individual cortical reorganization in aphasia recovery.

Assessment ◽  
2018 ◽  
Vol 27 (6) ◽  
pp. 1335-1348 ◽  
Author(s):  
Sarah McIvor Murray ◽  
Paul Bolton ◽  
Jeremy C. Kane ◽  
Daniel P. Lakin ◽  
Stephanie Skavenski Van Wyk ◽  
...  

There is a paucity of validated mental health measures for assessing psychological well-being among HIV-affected youth. We sought to explore the psychometric properties and validity of the Achenbach Youth Self-Report and Child Posttraumatic Stress Disorder Symptom Scale among orphans and vulnerable children (OVC) living in Lusaka, Zambia. These scales were administered to 210 OVC aged 13 to 17 years via audio computer-assisted self-interview. Confirmatory factor analysis was used to assess scale structure, Cronbach’s alpha for internal consistency, and correlations between scales related to mental or psychosocial health for construct validity. A known-groups validation was conducted using local identifications of youth with and without significant psychosocial problems, and test–retest reliability was assessed. Scales exhibited good internal reliability (α > .80), adequate criterion validity (area under the curve > .70), and moderate test–retest reliability (.62-.68). Findings support the utility of these symptom scales for identifying OVC experiencing significant psychosocial problems in Zambia.


NeuroImage ◽  
2013 ◽  
Vol 69 ◽  
pp. 231-243 ◽  
Author(s):  
Krzysztof J. Gorgolewski ◽  
Amos J. Storkey ◽  
Mark E. Bastin ◽  
Ian Whittle ◽  
Cyril Pernet

2018 ◽  
Vol 29 (02) ◽  
pp. 164-174 ◽  
Author(s):  
Gavin M. Bidelman ◽  
Monique Pousson ◽  
Calli Dugas ◽  
Amy Fehrenbach

AbstractAuditory-evoked potentials have proven useful in the objective evaluation of sound encoding at different stages of the auditory pathway (brainstem and cortex). Yet, their utility for use in clinical assessment and empirical research relies critically on the precision and test–retest repeatability of the measure.To determine how subcortical/cortical classes of auditory neural responses directly compare in terms of their internal consistency and test–retest reliability within and between listeners.A descriptive cohort study describing the dispersion of electrophysiological measures.Eight young, normal-hearing female listeners.We recorded auditory brainstem responses (ABRs), brainstem frequency-following responses (FFRs), and cortical (P1-N1-P2) auditory-evoked potentials elicited by speech sounds in the same set of listeners. We reassessed responses within each of four different test sessions over a period of 1 mo, allowing us to detect possible changes in latency/amplitude characteristics with finer detail than in previous studies.Our findings show that brainstem and cortical amplitude/latency measures are remarkably stable; with the exception of slight prolongation of the P1 wave, we found no significant variation in any response measure. Intraclass correlation analysis revealed that the speech-evoked FFR amplitude and latency measures achieved superior repeatability (intraclass correlation coefficient >0.85) among the more widely used obligatory brainstem (ABR) and cortical (P1-N1-P2) auditory-evoked potentials. Contrasting these intersubject effects, intrasubject variability (i.e., within-subject coefficient of variation) revealed that while latencies were more stable than amplitudes, brainstem and cortical responses did not differ in their variability at the single subject level.We conclude that (1) the variability of auditory neural responses increases with ascending level along the auditory neuroaxis (cortex > brainstem) between subjects but remains highly stable within subjects and (2) speech-FFRs might provide a more stable measure of auditory function than other conventional responses (e.g., click-ABR), given their lower inter- and intrasubject variability.


2014 ◽  
Vol 11 (6) ◽  
pp. 1111-1119 ◽  
Author(s):  
MeLisa Creamer ◽  
Heather R. Bowles ◽  
Belinda von Hofe ◽  
Kelley Pettee Gabriel ◽  
Harold W. Kohl ◽  
...  

Background:Computer-assisted techniques may be a useful way to enhance physical activity surveillance and increase accuracy of reported behaviors.Purpose:Evaluate the reliability and validity of a physical activity (PA) self-report instrument administered by telephone and internet.Methods:The telephone-administered Active Australia Survey was adapted into 2 forms for internet self-administration: survey questions only (internet-text) and with videos demonstrating intensity (internet-video). Data were collected from 158 adults (20–69 years, 61% female) assigned to telephone (telephone-interview) (n = 56), internet-text (n = 51), or internet-video (n = 51). Participants wore an accelerometer and completed a logbook for 7 days. Test-retest reliability was assessed using intraclass correlation coefficients (ICC). Convergent validity was assessed using Spearman correlations.Results:Strong test-retest reliability was observed for PA variables in the internet-text (ICC = 0.69 to 0.88), internet-video (ICC = 0.66 to 0.79), and telephone-interview (ICC = 0.69 to 0.92) groups (P-values < 0.001). For total PA, correlations (ρ) between the survey and Actigraph+logbook were ρ = 0.47 for the internet-text group, ρ = 0.57 for the internet-video group, and ρ = 0.65 for the telephone-interview group. For vigorous-intensity activity, the correlations between the survey and Actigraph+logbook were 0.52 for internet-text, 0.57 for internet-video, and 0.65 for telephone-interview (P < .05).Conclusions:Internet-video of the survey had similar test-retest reliability and convergent validity when compared with the telephone-interview, and should continue to be developed.


2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Jana Hoyer ◽  
Catharina Voss ◽  
Jens Strehle ◽  
John Venz ◽  
Lars Pieper ◽  
...  

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Jana Hoyer ◽  
Catharina Voss ◽  
Jens Strehle ◽  
John Venz ◽  
Lars Pieper ◽  
...  

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