scholarly journals Neurotropic Melanoma: The Management of Localised Disease

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Jeremy Croker ◽  
Bryan Burmeister ◽  
Matthew Foote
Keyword(s):  
Current Practice ◽  
Diagnostic Delay ◽  
Neck Region ◽  
Distant Metastases ◽  
Late Presentation ◽  
Salvage Treatment ◽  
Diagnostic Dilemma ◽  
Head And Neck Region ◽  
Disseminated Disease ◽  
The Brain

Neurotropic melanoma is a rare subtype of cutaneous malignant melanoma. Compared with conventional melanoma, it is more locally aggressive with an increased tendency for local recurrence but less likely for nodal or distant metastases. These tumours can be a diagnostic dilemma with a variety of morphological, histopathological, and immunophenotypical expressions. The often amelanotic, benign appearance may lead to treatment issues such as late presentation, diagnostic delay, misdiagnosis, insufficient surgical margins, and recurrence with resulting poor outcome. The neurotropic nature of the disease and prevalence in the head and neck region can result in perineural and neural invasion along named large nerves into the brain with resulting neuropathies. Wide local excision with adjuvant radiotherapy where indicated remains the current practice for treatment with chemotherapy predominately being reserved as a salvage treatment for patients with disseminated disease.

Periosteal Chondrosarcoma of the Maxilla

1995 ◽  
Vol 9 (1) ◽  
pp. 37-42
Author(s):  
Marc M. Kerner ◽  
Marilene B. Wang ◽  
Frank DiGregorio ◽  
Marilyn Zimmerman
Keyword(s):  
Head And Neck ◽  
Treatment Options ◽  
Neck Region ◽  
Long Bones ◽  
Diagnostic Dilemma ◽  
Head And Neck Region ◽  
Unusual Lesion

Primary chondrosarcomas of the head and neck region are exceedingly rare neoplasms. These lesions have clinical and histologic characteristics that make them difficult to discern from benign chondromas. Additionally, they may arise from the periosteum, making it even more difficult to distinguish them from osteosarcomas. We present a patient with a periosteal chondrosarcoma of the maxilla. Characteristic radiologic and histologic findings associated with this lesion are described. This is the first reported case of such a lesion in the maxilla, as previous reports of periosteal chondrosarcomas have involved long bones. The diagnostic dilemma posed by this extremely unusual lesion is discussed, as well as treatment options.

Adenoid cystic carcinoma of the salivary glands: Clinicopathological survey of 51 patients

1989 ◽  
Vol 103 (7) ◽  
pp. 675-679 ◽  
Author(s):  
V. N. Koka ◽  
R. M. Tiwari ◽  
I. van der Waal ◽  
G. B. Snow ◽  
J. Nauta ◽  
...  
Keyword(s):  
Adenoid Cystic Carcinoma ◽  
Radical Surgery ◽  
Neck Region ◽  
Distant Metastases ◽  
Head And Neck Region ◽  
Histological Features ◽  
Adenoid Cystic ◽  
Small Series ◽  
Clinicopathological Study

AbstractA clinicopathological study of 51 cases of adenoid cystic carcinoma in the head and neck region seen over a period of 20 years is presented. The correlation between various histological features and their impact on the results is attempted. Longterm results with respect to loco-regional recurrences, distant metastases and survival with various modalities of therapy are presented. Although this is a small series, radical surgery in keeping with the aim of avoiding undue mutilation, thus preserving the quality of life, followed by a full course of radiotherapy has been the mainstay of treatment and the results here presented justify this approach.

scholarly journals Solitary Plasmacytoma of The Jaws: Therapeutically Considerations and Prognosis: A Case Report

2021 ◽  
Vol 1 (1) ◽  
Author(s):  
Mohamed Hamdy Helal ◽  
Ahmed Mohamed Bader ◽  
Mohamed A. Fouad ◽  
Malak Yousef Mohamed shoukheba
Keyword(s):  
Soft Tissues ◽  
Plasma Cells ◽  
Malignant Neoplasm ◽  
Neck Region ◽  
Extramedullary Plasmacytoma ◽  
Solitary Plasmacytoma ◽  
Upper Respiratory Tract ◽  
Head And Neck Region ◽  
Plasma Cell Neoplasm ◽  
Disseminated Disease

The plasma cell neoplasm is a rare malignant neoplasm of plasma cells that may present as Extramedullary Plasmacytoma (EMP) in soft tissues especially in the upper respiratory tract, in the bone as a Solitary Plasmacytoma of bone (SPB), or as a part of the multifocal disseminated disease as Multiple Myeloma (MM). The majority of 80% occurs in the head and neck region. In our case, a 23-year-old female patient presented with a non-tender swelling of the gingiva in the upper and lower jaws with the mobility of all teeth. The radiological examination showed severe destruction of bone around all teeth.

scholarly journals Metastases of renal cell carcinoma to the larynx and thyroid: Two case reports on metastasis developing years after nephrectomy

2012 ◽  
Vol 6 (5) ◽  
Author(s):  
Lutfiye Demir ◽  
Cigdem Erten ◽  
Isil Somali ◽  
Alper Can ◽  
Ahmet Dirican ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Renal Cell ◽  
Case Reports ◽  
Neck Region ◽  
Metastatic Potential ◽  
Head And Neck Region ◽  
Neck Metastases ◽  
The Brain

Renal cell carcinoma (RCC) has a high metastatic potential due to its hematogen and vascular features. It metastasizes frequently to the lungs, the bones, the liver, the lymph nodes and the brain. Metastasis of RCC to the head and neck region is quite rare. In this case report, two RCC patients with head and neck metastases are presented: one occurring after 5 years and the other occurring 17 years after diagnosis.

scholarly journals Cytodiagnosis of extra-nasal rhinosporidiosis: A study of 16 cases from endemic area

2014 ◽  
Vol 6 (02) ◽  
pp. 080-083
Author(s):  
Subrata Pal ◽  
Srabani Chakrabarti ◽  
Biplab Kr Biswas ◽  
Rajani Sinha ◽  
Arindam Rakshit ◽  
...  
Keyword(s):  
Head And Neck ◽  
Fine Needle Aspiration ◽  
Preoperative Diagnosis ◽  
False Negative ◽  
Neck Region ◽  
Needle Aspiration ◽  
Diagnostic Dilemma ◽  
Head And Neck Region ◽  
Fine Needle ◽  
Negative Case

ABSTRACT Context: Extra-nasal rhinosporidiosis is not uncommon in endemic region like India. Clinical presentations of extra-nasal rhinosporidiosis lesion often lead to diagnostic dilemma. Cytology can help in the preoperative diagnosis of such lesions. Aims: The aims of our study were to find the clinico-pathological presentation of extra-nasal rhinosporidiosis and to evaluate the role of cytology in diagnosing these lesions preoperatively. Settings and Design: Fine-needle aspiration cytology is often used for preoperative diagnosis of sub-cutaneous lesions of the head and neck region. This retrospective study was designed to include the cytologically diagnosed cases of rhinosporidiosis and to compare with final histopathology of the lesions. Materials and Methods: A total of 21 cases of extra-nasal rhinosporidiosis were diagnosed in our study period of 18 months. Cytology was approached in 17 cases and 16 cases were diagnosed as rhinosporidiosis, which were included in the study group. Twelve cases were sampled by fine-needle aspiration and four cases by scrap technique. Histopathological confirmation was possible in all cytologically diagnosed cases. Results: Head and neck region were involved in 15 cases and only one case was on the skin of right upper arm. Orbital region was the most common extra-nasal site of involvement. Most of the cases (13 cases, 81.25%) belonged to the age group of 11-30 years. All cytologicaly diagnosed cases of rhinosporidiosis were concordant with histopathology. Only one false-negative case was cytologically diagnosed as suppurative inflammatory lesion. Sensitivity and specificity of cytology in diagnosis of extra-nasal rhinosporidiosis were 94.11% and 100% respectively. Conclusions: Extra-nasal rhinosporidiosis is an important differential diagnosis of nodular, polypoid mass of head-neck-face region. Cytology can be used as an important tool in preoperative diagnosis of extra-nasal rhinosporidiosis.

Malignant Fibrous Xanthoma of The Lip

1980 ◽  
Vol 88 (2) ◽  
pp. 154-156 ◽  
Author(s):  
James H. Brandenburg ◽  
Terrence W. Frank
Keyword(s):  
Head And Neck ◽  
Neck Region ◽  
Distant Metastases ◽  
Lower Lip ◽  
Head And Neck Region ◽  
Local Recurrences ◽  
Atypical Fibroxanthoma

Malignant fibroxanthoma is a most unusual tumor, especially when arising in the head and neck region. A patient with such a tumor arising in the lower lip is presented. This case was characterized by local recurrences, as well as regional and distant metastases. The differentiation between atypical fibroxanthoma and malignant fibroxanthoma is discussed.

scholarly journals Sarcomatoid Lesions of Head and Neck Region: A Diagnostic Dilemma

2021 ◽  
pp. 283-293
Author(s):  
Dipankar Samaddar ◽  
Ananjan Chatterjee ◽  
. Abhinandan ◽  
Deepak Kumar ◽  
. Akriti
Keyword(s):  
Differential Diagnosis ◽  
Head And Neck ◽  
Spindle Cell ◽  
Neck Region ◽  
Spindle Cell Carcinoma ◽  
Diagnostic Challenge ◽  
Diagnostic Dilemma ◽  
Fracture Callus ◽  
Head And Neck Region ◽  
The Way

One challenging feature of head and neck pathology is that a dizzying array of sarcomatoid lesions occurs here ranging all the way from reactive to malignant and very aggressive. This makes accurate diagnosis critical. These lesions are quite diverse with great clinical and biological heterogeneity. Some are malignant while many others are benign or simply reactive in nature. For example; at mucosal sites, a well known lesion is spindle cell carcinoma (SpCC), which are overtly malignant, and the differential diagnosis then includes a number of different malignant spindle cell lesions. However, there are several benign or even non-neoplastic lesions that can sometimes be difficult to discern from SpCC, e.g. Nodular fasciitis, Proliferative myositis, Cellular schwannoma, Benign fibrous histiocytoma, Carcino sarcoma, Sarcomatoid melanoma. Fracture callus, etc. Aim of Study: There is a diagnostic challenge to the oral pathologists to differentiate dizzying array of sarcoma like lesions from other similar microscopic simulates ranging all the way from reactive to malignant and very aggressive. This article aims to review the sarcomatoid lesions of the head and neck region with emphasis on differential diagnosis histologically and immunohistochemicaly.

Submandibular neurilemmoma; a diagnostic dilemma

2004 ◽  
Vol 118 (2) ◽  
pp. 156-158 ◽  
Author(s):  
Robert Almeyda ◽  
Prasad Kothari ◽  
Ha Chau ◽  
Vincent Cumberworth
Keyword(s):  
Head And Neck ◽  
Neck Region ◽  
Signs And Symptoms ◽  
Benign Neoplasms ◽  
Diagnostic Dilemma ◽  
Head And Neck Region ◽  
Neurological Signs ◽  
Nerve Sheath ◽  
Diagnostic Difficulties ◽  
Slow Growing

Neurilemmomas are slow growing, benign neoplasms of neural crest Schwann cell origin. They arise from any peripheral, spinal or cranial nerve except the olfactory and optic. Presentation is usually asymptomatic but focal neurological signs and symptoms may be associated with nerve compression. With approximately one third of all documented cases presenting in the head and neck region, we report a case of a submandibular neurilemmoma misdiagnosed pre-operatively. The diagnostic difficulties are discussed and the current literature reviewed. Thiscase highlights the importance of inclusion of nerve sheath tumours in differential diagnoses of soft tissue lesions in the head and neck.

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