scholarly journals Stability Analysis of a Vector-Borne Disease with Variable Human Population

2013 ◽  
Vol 2013 ◽  
pp. 1-12 ◽  
Author(s):  
Muhammad Ozair ◽  
Abid Ali Lashari ◽  
Il Hyo Jung ◽  
Young Il Seo ◽  
Byul Nim Kim
Keyword(s):  
Mathematical Model ◽  
Human Population ◽  
Feasible Region ◽  
Asymptotically Stable ◽  
Globally Asymptotically Stable ◽  
Vector Borne Disease ◽  
Vector Borne ◽  
Theoretical Results ◽  
Disease Free ◽  
Varying Population

A mathematical model of a vector-borne disease involving variable human population is analyzed. The varying population size includes a term for disease-related deaths. Equilibria and stability are determined for the system of ordinary differential equations. IfR0≤1, the disease-“free” equilibrium is globally asymptotically stable and the disease always dies out. IfR0>1, a unique “endemic” equilibrium is globally asymptotically stable in the interior of feasible region and the disease persists at the “endemic” level. Our theoretical results are sustained by numerical simulations.

scholarly journals Dynamics of Rabies Epidemics in Vampire Bats

Complexity ◽  
2020 ◽  
Vol 2020 ◽  
pp. 1-11
Author(s):  
Liang Tian ◽  
Juping Zhang
Keyword(s):  
Numerical Simulation ◽  
Mathematical Model ◽  
Theoretical Basis ◽  
Asymptotically Stable ◽  
Globally Asymptotically Stable ◽  
Vampire Bats ◽  
Bat Rabies ◽  
Vampire Bat ◽  
Theoretical Results ◽  
Disease Free

In order to study the transmission of rabies epidemics in vampire bats, we propose a mathematical model for vampire bat rabies virus. A threshold R0 is identified which determines the outcome of the disease. If R0<1, the disease-free equilibrium is globally asymptotically stable, and if R0>1, the endemic equilibrium is globally asymptotically stable with certain conditions. Through the numerical simulation, the correctness of the theoretical results is verified. We carry out the sensitivity analysis of the parameters which provide a theoretical basis for preventing and controlling the transmission of bat rabies.

scholarly journals A Delay Differential Equation Model of HIV Infection, with Therapy and CTL Response

2014 ◽  
Vol 9 ◽  
pp. 53-68 ◽  
Author(s):  
B. El Boukari ◽  
N. Yousfi
Keyword(s):  
Reproduction Number ◽  
Equation Model ◽  
Asymptotically Stable ◽  
Differential Equation Model ◽  
Globally Asymptotically Stable ◽  
Intracellular Delay ◽  
Immunodeficiency Virus ◽  
Delay Differential ◽  
Theoretical Results ◽  
Disease Free

In this work we investigate a new mathematical model that describes the interactions betweenCD4+ T cells, human immunodeficiency virus (HIV), immune response and therapy with two drugs.Also an intracellular delay is incorporated into the model to express the lag between the time thevirus contacts a target cell and the time the cell becomes actively infected. The model dynamicsis completely defined by the basic reproduction number R0. If R0 ≤ 1 the disease-free equilibriumis globally asymptotically stable, and if R0 > 1, two endemic steady states exist, and their localstability depends on value of R0. We show that the intracellular delay affects on value of R0 becausea larger intracellular delay can reduce the value of R0 to below one. Finally, numerical simulationsare presented to illustrate our theoretical results.

A mathematical analysis of a tuberculosis epidemic model with two treatments and exogenous re-infection

2020 ◽  
pp. 2050082
Author(s):  
Mehdi Lotfi ◽  
Azizeh Jabbari ◽  
Hossein Kheiri
Keyword(s):  
Mathematical Model ◽  
Asymptotic Stability ◽  
Stable Disease ◽  
Reproduction Number ◽  
Geometric Approach ◽  
Backward Bifurcation ◽  
Asymptotically Stable ◽  
Globally Asymptotically Stable ◽  
Bifurcation Phenomenon ◽  
Disease Free

In this paper, we propose a mathematical model of tuberculosis with two treatments and exogenous re-infection, in which the treatment is effective for a number of infectious individuals and it fails for some other infectious individuals who are being treated. We show that the model exhibits the phenomenon of backward bifurcation, where a stable disease-free equilibrium coexists with a stable endemic equilibria when the related basic reproduction number is less than unity. Also, it is shown that under certain conditions the model cannot exhibit backward bifurcation. Furthermore, it is shown in the absence of re-infection, the backward bifurcation phenomenon does not exist, in which the disease-free equilibrium of the model is globally asymptotically stable when the associated reproduction number is less than unity. The global asymptotic stability of the endemic equilibrium, when the associated reproduction number is greater than unity, is established using the geometric approach. Numerical simulations are presented to illustrate our main results.

scholarly journals A MODEL FOR CONTROL OF HIV/AIDS WITH PARENTAL CARE

2013 ◽  
Vol 06 (02) ◽  
pp. 1350006 ◽  
Author(s):  
GBENGA JACOB ABIODUN ◽  
NIZAR MARCUS ◽  
KAZEEM OARE OKOSUN ◽  
PETER JOSEPH WITBOOI
Keyword(s):  
Mathematical Model ◽  
Parental Care ◽  
Optimal Strategies ◽  
Asymptotically Stable ◽  
Globally Asymptotically Stable ◽  
Qualitative And Quantitative ◽  
Aids Epidemic ◽  
Quantitative Analyses ◽  
Disease Free ◽  
Hiv Aids

In this study we investigate the HIV/AIDS epidemic in a population which experiences a significant flow of immigrants. We derive and analyze a mathematical model that describes the dynamics of HIV infection among the immigrant youths and how parental care can minimize or prevent the spread of the disease in the population. We analyze the model with both screening control and parental care, then investigate its stability and sensitivity behavior. We also conduct both qualitative and quantitative analyses. It is observed that in the absence of infected youths, disease-free equilibrium is achievable and is globally asymptotically stable. We establish optimal strategies for the control of the disease with screening and parental care, and provide numerical simulations to illustrate the analytic results.

scholarly journals On the Global Dynamics of a Vector-Borne Disease Model with Age of Vaccination

2018 ◽  
Vol 2018 ◽  
pp. 1-11 ◽  
Author(s):  
Stanislas Ouaro ◽  
Ali Traoré
Keyword(s):  
Basic Reproduction Number ◽  
Reproduction Number ◽  
Mass Action ◽  
Global Dynamics ◽  
Asymptotically Stable ◽  
Globally Asymptotically Stable ◽  
Vector Borne Disease ◽  
Special Cases ◽  
Vector Borne ◽  
The Basic Reproduction Number

We study a vector-borne disease with age of vaccination. A nonlinear incidence rate including mass action and saturating incidence as special cases is considered. The global dynamics of the equilibria are investigated and we show that if the basic reproduction number is less than 1, then the disease-free equilibrium is globally asymptotically stable; that is, the disease dies out, while if the basic reproduction number is larger than 1, then the endemic equilibrium is globally asymptotically stable, which means that the disease persists in the population. Using the basic reproduction number, we derive a vaccination coverage rate that is required for disease control and elimination.

scholarly journals Modeling Transmission of Tuberculosis with MDR and Undetected Cases

2011 ◽  
Vol 2011 ◽  
pp. 1-12 ◽  
Author(s):  
Yongqi Liu ◽  
Zhendong Sun ◽  
Guiquan Sun ◽  
Qiu Zhong ◽  
Li Jiang ◽  
...  
Keyword(s):  
Mathematical Model ◽  
Theoretical Analysis ◽  
Control Strategies ◽  
Multidrug Resistant ◽  
Vital Role ◽  
Endemic Equilibrium ◽  
Asymptotically Stable ◽  
Globally Asymptotically Stable ◽  
Tb Control ◽  
Disease Free

This paper presents a novel mathematical model with multidrug-resistant (MDR) and undetected TB cases. The theoretical analysis indicates that the disease-free equilibrium is globally asymptotically stable ifR0<1; otherwise, the system may exist a locally asymptotically stable endemic equilibrium. The model is also used to simulate and predict TB epidemic in Guangdong. The results imply that our model is in agreement with actual data and the undetected rate plays vital role in the TB trend. Our model also implies that TB cannot be eradicated from population if it continues to implement current TB control strategies.

scholarly journals A Mathematical Model of COVID-19 Pandemic: A Case Study of Bangkok, Thailand

2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
Pakwan Riyapan ◽  
Sherif Eneye Shuaib ◽  
Arthit Intarasit
Keyword(s):  
Mathematical Model ◽  
Reproduction Number ◽  
Transmission Dynamics ◽  
Asymptotically Stable ◽  
Globally Asymptotically Stable ◽  
Proposed Model ◽  
Next Generation Matrix ◽  
Disease Free ◽  
The Basic Reproduction Number

In this study, we propose a new mathematical model and analyze it to understand the transmission dynamics of the COVID-19 pandemic in Bangkok, Thailand. It is divided into seven compartmental classes, namely, susceptible S , exposed E , symptomatically infected I s , asymptomatically infected I a , quarantined Q , recovered R , and death D , respectively. The next-generation matrix approach was used to compute the basic reproduction number denoted as R cvd 19 of the proposed model. The results show that the disease-free equilibrium is globally asymptotically stable if R cvd 19 < 1 . On the other hand, the global asymptotic stability of the endemic equilibrium occurs if R cvd 19 > 1 . The mathematical analysis of the model is supported using numerical simulations. Moreover, the model’s analysis and numerical results prove that the consistent use of face masks would go on a long way in reducing the COVID-19 pandemic.

scholarly journals Stability of a Mathematical Model of Malaria Transmission with Relapse

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Hai-Feng Huo ◽  
Guang-Ming Qiu
Keyword(s):  
Mathematical Model ◽  
Basic Reproduction Number ◽  
Recovery Rate ◽  
Reproduction Number ◽  
Asymptotically Stable ◽  
Globally Asymptotically Stable ◽  
Next Generation Matrix ◽  
The Government ◽  
Disease Free ◽  
The Basic Reproduction Number

A more realistic mathematical model of malaria is introduced, in which we not only consider the recovered humans return to the susceptible class, but also consider the recovered humans return to the infectious class. The basic reproduction numberR0is calculated by next generation matrix method. It is shown that the disease-free equilibrium is globally asymptotically stable ifR0≤1, and the system is uniformly persistence ifR0>1. Some numerical simulations are also given to explain our analytical results. Our results show that to control and eradicate the malaria, it is very necessary for the government to decrease the relapse rate and increase the recovery rate.

scholarly journals Global Dynamics of a Discrete-Time MERS-Cov Model

Mathematics ◽  
2021 ◽  
Vol 9 (5) ◽  
pp. 563
Author(s):  
Mahmoud H. DarAssi ◽  
Mohammad A. Safi ◽  
Morad Ahmad
Keyword(s):  
Discrete Time ◽  
Global Attractivity ◽  
Endemic Equilibrium ◽  
Global Dynamics ◽  
Asymptotically Stable ◽  
Globally Asymptotically Stable ◽  
Proposed Model ◽  
Threshold Conditions ◽  
Theoretical Results ◽  
Disease Free

In this paper, we have investigated the global dynamics of a discrete-time middle east respiratory syndrome (MERS-Cov) model. The proposed discrete model was analyzed and the threshold conditions for the global attractivity of the disease-free equilibrium (DFE) and the endemic equilibrium are established. We proved that the DFE is globally asymptotically stable when R0≤1. Whenever R˜0>1, the proposed model has a unique endemic equilibrium that is globally asymptotically stable. The theoretical results are illustrated by a numerical simulation.

scholarly journals Dynamics of Fractional-Order Epidemic Models with General Nonlinear Incidence Rate and Time-Delay

Mathematics ◽  
2021 ◽  
Vol 9 (15) ◽  
pp. 1829
Author(s):  
Ardak Kashkynbayev ◽  
Fathalla A. Rihan
Keyword(s):  
Steady State ◽  
Time Delay ◽  
Incidence Rate ◽  
Fractional Order ◽  
Asymptotically Stable ◽  
Nonlinear Incidence Rate ◽  
Globally Asymptotically Stable ◽  
Nonlinear Incidence ◽  
Theoretical Results ◽  
Disease Free

In this paper, we study the dynamics of a fractional-order epidemic model with general nonlinear incidence rate functionals and time-delay. We investigate the local and global stability of the steady-states. We deduce the basic reproductive threshold parameter, so that if R0<1, the disease-free steady-state is locally and globally asymptotically stable. However, for R0>1, there exists a positive (endemic) steady-state which is locally and globally asymptotically stable. A Holling type III response function is considered in the numerical simulations to illustrate the effectiveness of the theoretical results.

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