scholarly journals Role of Carbamazepine in the Symptomatic Treatment of Subacute Sclerosing Panencephalitis: A Case Report and Review of the Literature

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Sandhya Ravikumar ◽  
John Ross Crawford

We describe the clinical presentation and clinical course of subacute sclerosing panencephalitis in a 13-year-old previously healthy boy who recently immigrated to the United States from Iraq. He presented with macular retinopathy, followed by progressive myoclonus and encephalopathy. After extensive workup, a diagnosis of subacute sclerosing panencephalitis was suspected by the presence of period epileptiform discharges on electroencephalogram and confirmed by elevated measles titers in the cerebrospinal fluid. Combination immunomodulatory therapy with isoprinosine, ribavirin, and intra-Ommaya interferon alpha did not result in clinical improvement. Within days following the administration of carbamazepine, there was remarkable improvement in the myoclonus and he was able to ambulate independently for a period of 4 months at which time he unfortunately progressed to a vegetative state. This case highlights the importance of carbamazepine as a potential first line symptomatic treatment of subacute sclerosing panencephalitis and provides a review of the literature on the subject.

2018 ◽  
Vol 23 (3) ◽  
pp. 233-249 ◽  
Author(s):  
Eric Bonetto ◽  
Fabien Girandola ◽  
Grégory Lo Monaco

Abstract. This contribution consists of a critical review of the literature about the articulation of two traditionally separated theoretical fields: social representations and commitment. Besides consulting various works and communications, a bibliographic search was carried out (between February and December, 2016) on various databases using the keywords “commitment” and “social representation,” in the singular and in the plural, in French and in English. Articles published in English or in French, that explicitly made reference to both terms, were included. The relations between commitment and social representations are approached according to two approaches or complementary lines. The first line follows the role of commitment in the representational dynamics: how can commitment transform the representations? This articulation gathers most of the work on the topic. The second line envisages the social representations as determinants of commitment procedures: how can these representations influence the effects of commitment procedures? This literature review will identify unexploited tracks, as well as research perspectives for both areas of research.


Author(s):  
Arthur L. Frank

This chapter considers the role and value of the study of the humanities in medical education. Most authors on this subject believe the study of the humanities results in a better physician. However, few papers document this almost universally accepted idea. This chapter cites the available literature on the subject and also considers how the study of the humanities has become more common in countries beyond the United States. The study of the humanities is thought to improve physician communication and to influence ethical behaviors, ultimately improving patient care.


2018 ◽  
Vol 35 (02) ◽  
pp. 116-121 ◽  
Author(s):  
Tamir Friedman ◽  
Keith Quencer ◽  
David Madoff ◽  
Ronald Winokur

AbstractPulmonary embolism (PE) is currently the third leading cause of death and moreover is likely underdiagnosed. PE remains the most common preventable cause of hospital deaths in the United States, which may be attributable to its diagnostic challenges. Although difficult to diagnose, patient mortality rates are time-dependent, and thus, the suspicion and diagnosis of PE in a timely manner is imperative. Diagnosis based on several criteria which may dictate imaging workup as well as laboratory tests and clinical parameters are discussed. The evolution of treatment guidelines via various clinical trials and recommendations is outlined, setting the stage for the use of fibrinolytics, whether systemic or catheter directed. Treatment, including fibrinolytics, is predicated on patient triage into three large categories—massive, submassive, or low-risk PE. Additionally, a relatively new concept of a multidisciplinary team composed of several subspecialty experts known as the PE response team (PERT) is discussed. PERT's timely and unified recommendations have been shown to optimize care and decrease mortality while tailoring treatment to each individual afflicted by PE.


Author(s):  
John Charlot

That the Mexican mural renaissance is understudied is clear from the fact than not one of its artists has been the subject of a scholarly biography. Moreover, the movement as a whole has usually been viewed through nationalist prejudices and partisan interpretations. A current reevaluation uses the wedge of several hitherto marginalized artists who figure more prominently in documents and chronology than in popular history. Among them, Jean Charlot can be placed securely at the beginning of several major developments, which were continuations of his work in France. At the open air art school of Coyoacán, he helped the young teachers move from impressionism to a geometry-based postimpressionism more appropriate for mural composition. He introduced woodcut, which he had practiced in France and which became the print medium of choice for generations of Mexican artists. His first mural, The Massacre in the Main Temple, was important for its successful use of fresco—immediately adopted as the preferred medium by other muralists—and its dynamic geometric composition, an alternative to Diego Rivera’s static classicism in Creation. Charlot further broadened the thematic and stylistic options of the movement in a series of small oils and in the first studies of the indigenous nude. He continued to nourish his colleagues with the results of his work as an archeological draughtsman at the Chichen Itza expedition of the Carnegie Institution of Washington, DC. Charlot also participated in the notable collaboration between artists and writers in 1920s Mexico. Along with Manuel Maples Arce, he was on the two-man Direction Committee of the estridentista movement, illustrating books of poetry and joining group exhibitions. His writings are among the earliest discussions of contemporary Mexican art—publicizing the movement in Europe and the United States—and continue to influence interpretation today. His collections of documents and interviews, as well as his personal experience, became the invaluable basis of books like his The Mexican Mural Renaissance, 1920–1925 and numerous articles in several languages. His latest bibliography is 173 pages long. Charlot fulfilled the unique role of insider-outsider, participant-observer, in the Mexican mural renaissance.


Author(s):  
Charles O. Jones

The creative work involved in writing the Constitution of the United States in Philadelphia in 1787 has been interpreted and analysed in political and policy debate ever since. ‘Inventing the Presidency’ considers how the Founders of the United States tried to create unity in a separated system. Why was the title of president selected? What was the role of president going to look like? How long should the single executive serve? Should the person be term-limited? Providing a legislative or law-making role for the president was the subject of considerable debate at the beginning. Inventors solve problems: they tinker until they have a workable device. The creation of the presidency was a process of trial and error.


2019 ◽  
Vol 7 ◽  
pp. 2050313X1982643
Author(s):  
Julia N Mayba ◽  
C Nicole Hawkins

We present a case of Sneddon-Wilkinson disease in a 52-year-old female at her first presentation to dermatology. Outlined in the case are various investigations undertaken at this initial presentation, including rheumatologic and hematologic malignancy markers, which identified immunoglobulin A gammopathy. The systemic and topical therapies used to treat the patient’s condition are described, as well as her response to these treatments. In this discussion, we explain the epidemiology, pathophysiology, and clinical presentation of Sneddon-Wilkinson disease. Various medical conditions having known association with Sneddon-Wilkinson disease are discussed, including immunoglobulin A or immunoglobulin G monoclonal gammopathies and lymphoproliferative disorders. A comprehensive differential diagnosis for Sneddon-Wilkinson disease is provided, including immunoglobulin A pemphigus, acute generalized exanthematous pustulosis and pustular psoriasis, among others. We describe the systemic and topical therapy options for the treatment of Sneddon-Wilkinson disease, of which first line treatment is systemic dapsone. This patient serves as an excellent case of Sneddon-Wilkinson disease with unexpected immunoglobulin A gammopathy.


1978 ◽  
Vol 6 (1) ◽  
pp. 15-25
Author(s):  
Terry Calvani

The attempt by the United States government to preserve competition and its benefits has produced a succession of legislation, popularly known as the antitrust laws, which began with the Sherman Antitrust Act of 1890. This law prohibits combinations in restraint of trade and monopolization of trade. The Federal Trade Commission Act of 1914 established a federal agency to enforce antitrust and outlawed “unfair” competition. The Clayton Act, passed in the same year and amended by the Robinson–Patman Act in 1936, forbids price discrimination, mergers, and other actions when judged destructive of competition.These statutes have generated an enormous quantity of litigation and have stimulated a plethora of literature. The following article, written by an expert who teaches and writes in the. field of antitrust, describes the more important works on the subject which, taken together, could constitute a basic collection of antitrust literature for law libraries inside and outside the United Slates.


1985 ◽  
Vol 57 (2) ◽  
pp. 367-382 ◽  
Author(s):  
D. H. Dickson ◽  
I. W. Kelly

This review summarizes to date the research on the Barnum effect, the tendency for people to accept vague, ambiguous, and general statements as descriptive of their unique personalities. Studies examined address interpretation variables of the Barnum profiles in regard to generality and supposed relevance of the interpretation, favorability of interpretation, type of assessment procedure, and origin and format of interpretation. Also the role of personal factors such as characteristics of the subject and test administrator are examined. It is concluded that the level of acceptance of Barnum profiles depends on the relevance and favorability of the profile and to some extent on the type of assessment utilized. Directions for research on the Barnum effect are provided.


1950 ◽  
Vol 3 (1) ◽  
pp. 72-87
Author(s):  
Janet Besse ◽  
Harold D. Lasswell

Opinion differs about the role of syndicated columnists in the forming of national opinion and in the decision-making process in the United States. Our columnists have been the subject of pioneering studies, but we have a long way to go before the picture can be called historically complete, scientifically precise, or fully satisfactory for policy-making purposes. What the columnists say is an important chapter in the history of the American public, and history is most useful for critical purposes when written close to the event. The general theory of communication and politics can be refined as the details of the opinion process are more fully known.


Author(s):  
Lilia Ana Sandoval Pineda ◽  
Jorge Enrique Quevedo Reyes

El artículo tiene como objetivo presentar la actualidad de la evaluación formativa en el tema de diseño bases de datos para entornos virtuales, en donde se mencionan las plataformas virtuales con sus estrategias de evaluación convencional para áreas afines con la ingeniería. Entre los principales aspectos en que se centra la revisión de la literatura esta la taxonomía de Bloom, entornos virtuales, plataformas y evaluación formativa. Desde el punto de vista teórico se centra en el tema de diseño de las bases de datos, las metodologías de evaluación y las diferentes alternativas para ambientes virtuales, enfatizando en los recursos y formas como se afrontan en la actualidad. También se tiene en cuenta el papel del estudiante y del docente en el proceso de evaluación y realimentación del aprendizaje. Luego de experimentar y evaluar desde el punto de vista evaluación formativa, tanto las plataformas estándar, como también los proyectos desarrollados por institutos y universidades, se concluye que las plataformas ni siquiera tienen en cuenta este tipo de evaluación y los resultados obtenidos por proyectos particulares no son suficientes para cubrir un proceso real y completo de este tipo de evaluación.Palabras Clave: Entorno Virtual, Evaluación formativa, Diseño de base datos.This article aims to present the current of formative assessment for the subject of database design for virtual environments where virtual platforms mentioned with conventional assessment strategies for areas related to engineering. Among the main issues focused review of the literature is Bloom's taxonomy, virtual environments, platforms, and educational assessment. From the theoretical point of view focuses on the design theme of the databases, assessment methodologies and the different alternatives for virtual environments, emphasizing resources and forms as encountered today. It also takes into account the role of the student and the teacher in the process of assessment and feedback of learning. After experimenting and evaluating from the point of view formative assessment, both standard platforms, as the projects developed by colleges and universities, it is concluded that the platforms do not even take into account this type of assessment and the results obtained for particular projects, not sufficient to cover actual and complete a process of this type of assessment.Keywords: Virtual Environment, formative evaluation, Designed data base


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